Changes in osteoblast, chondrocyte, and adipocyte lineages mediate the bone anabolic actions of PTH and small molecule GSK-3 inhibitor

Journal of Cellular Biochemistry

Volumn 102, Issue 6, 2007, Pages 1504-1518

  Kulkarni, Nalini H ^a   Wei, Tao ^a   Kumar, Amar ^a   Dow, Ernst R ^a   Stewart, Trent R ^a   Shou, Jianyong ^a   N'cho, Mathias ^a   Sterchi, Diane L ^a   Gitter, Bruce D ^a   Higgs, Richard E ^a   Halladay, David L ^a   Engler, Thomas A ^a   Martin, T John ^b   Bryant, Henry U ^a   Ma, Yanfei L ^a   Onyia, Jude E ^a  

^a ELI LILLY AND COMPANY   (United States)

^b ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

Adipogenesis; Chondrogenesis; Gene arrays; GSK 3 inhibitor; Osteogenesis; Ovariectomy; Parathyroid hormone

Indexed keywords

ANABOLIC AGENT; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; LIPID; PARATHYROID HORMONE; RNA;

ADIPOCYTE; ADIPOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BONE DENSITY; BONE DEVELOPMENT; CARTILAGE CELL; CELL DIFFERENTIATION; CELL GROWTH; CELL LINEAGE; CHONDROGENESIS; COLONY FORMING UNIT F; CONTROLLED STUDY; DRUG MECHANISM; EX VIVO STUDY; FEMALE; GENE EXPRESSION; HISTOLOGY; LIPID METABOLISM; METAPHYSIS; MORPHOGENESIS; NONHUMAN; OSTEOBLAST; OSTEOPENIA; OVARIECTOMY; PRIORITY JOURNAL; RAT; TREATMENT DURATION;

ADIPOCYTES; ALKALINE PHOSPHATASE; ANIMALS; BIOLOGICAL MARKERS; BONE MARROW CELLS; CELL LINEAGE; CELLS, CULTURED; CHONDROCYTES; DISEASE MODELS, ANIMAL; DRUG ADMINISTRATION SCHEDULE; ENZYME INHIBITORS; FEMALE; GENE EXPRESSION; GLYCOGEN SYNTHASE KINASE 3; HUMANS; INJECTIONS, SUBCUTANEOUS; MODELS, BIOLOGICAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OSTEOBLASTS; OVARIECTOMY; PARATHYROID HORMONE; PEPTIDE FRAGMENTS; RATS; RATS, SPRAGUE-DAWLEY; STEM CELLS; STROMAL CELLS; TIBIA; TIME FACTORS;

ANIMALIA; RATTUS;

EID: 36849019961     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.21374     Document Type: Article

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