Chronic liver disease in an ageing population

Age and Ageing

Volumn 38, Issue 1, 2009, Pages 11-18

  Frith, James ^a   Jones, David ^a   Newton, Julia L ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Chronic; Elderly; Liver disease

Indexed keywords

ADEFOVIR; ANTIVIRUS AGENT; AZATHIOPRINE; BENZODIAZEPINE DERIVATIVE; ENTECAVIR; INTERFERON; LACTULOSE; LAMIVUDINE; MINERALOCORTICOID ANTAGONIST; PEGINTERFERON; PREDNISOLONE; RECOMBINANT INTERFERON; RIBAVIRIN; TELBIVUDINE; URSODEOXYCHOLIC ACID;

AGED; AGING; ALCOHOL LIVER DISEASE; ALCOHOL WITHDRAWAL; ALPHA 1 ANTITRYPSIN DEFICIENCY; ASCITES; ATAXIA; AUTOIMMUNE HEPATITIS; CHRONIC LIVER DISEASE; CLINICAL FEATURE; COMBINATION CHEMOTHERAPY; CONFUSION; DROWSINESS; DRUG HALF LIFE; EARLY DIAGNOSIS; EARLY INTERVENTION; ELDERLY CARE; FALLING; FATIGUE; FLUID THERAPY; HEMOCHROMATOSIS; HEPATIC ENCEPHALOPATHY; HEPATITIS B; HEPATITIS C; HUMAN; INCONTINENCE; LABORATORY TEST; LIVER BIOPSY; LIVER CELL CARCINOMA; LIVER FUNCTION TEST; LIVER TRANSPLANTATION; MONOTHERAPY; MORBIDITY; MORTALITY; NONALCOHOLIC FATTY LIVER; PARACENTESIS; PATIENT REFERRAL; PATIENT SAFETY; PHLEBOTOMY; PRIMARY BILIARY CIRRHOSIS; PRIMARY SCLEROSING CHOLANGITIS; PRIORITY JOURNAL; PROGNOSIS; REVIEW; SEDATION; SIDE EFFECT; TRANSJUGULAR INTRAHEPATIC PORTOSYSTEMIC SHUNT; UNSPECIFIED SIDE EFFECT; WEIGHT CONTROL; WILSON DISEASE;

AGE FACTORS; AGED; AGED, 80 AND OVER; BIOPSY; CHRONIC DISEASE; FEMALE; GERIATRIC ASSESSMENT; HUMANS; LIVER; LIVER DISEASES; LIVER FUNCTION TESTS; MALE; MIDDLE AGED; PREVALENCE;

EID: 58849146199     PISSN: 00020729     EISSN: 14682834     Source Type: Journal    
DOI: 10.1093/ageing/afn242     Document Type: Review

References (30)

1. Gilmore I, Burroughs A, Murray-Lyon I et al. Indications, methods and outcomes of percutaneous liver biopsy in England and Wales: An audit by the British Society of Gastroenterology and the Royal College of Physicians of London. Gut 1995; 36: 437-41.
2. Gines P, Arroyo V, Quintero E et al. Comparison of paracentesis and diuretics in the treatment of cirrhotics with tense ascites. Results of a randomized study. Gastroenterology 1987; 93: 234-41.
3. Deschenes M, Dufresne MP, Bui B et al. Predictors of clinical response to transjugular intrahepatic portosystemic shunt (TIPS) in cirrhotic patients with refractory ascites. Am J Gastroenterol 1999; 94: 1361-5.
4. Collins B, Pirsch J, Becker Y et al. Long-term results of liver transplantation in patients 60 years of age and older. Transplantation 2000; 70: 780-3.
5. Woodhouse K, James O. Alcoholic liver disease in the elderly: presentation and outcome. Age Ageing 1985; 14: 113-8.
6. Potter J, James O. Clinical features and prognosis of alcoholic liver disease in respect of advancing age. Gerontology 1987; 33: 380-7.
7. Kruse WH. Problems and pitfalls in the use of benzodiazepines in the elderly. Drug Saf 1990; 5: 328-44.
8. Harrison SA, Day CP. Benefits of lifestyle modification in NAFLD. Gut 2007; 56: 1760-9.
9. Angulo P, Keach J, Batts K et al. Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis. Hepatology 1999; 30: 1356-62.
10. Miyaaki H, Ichikawa T, Nakao K et al. Clinicopathological study of nonalcoholic fatty liver disease in Japan: The risk factors for fibrosis. Liver Int 2008; 28: 519-24.
11. Newton J, Burt A, Park J et al. Autoimmune hepatitis in older patients. Age Ageing 1997; 26: 441-4.
12. Schramm C, Kanzler S, Meyer zum Buschenfelde K et al. Autoimmune hepatitis in the elderly. Am J Gastroenterol 2001; 96: 1587-91.
13. Al-Chalabi T, Boccato S, Portmann B et al. Autoimmune hepatitis (AIH) in the elderly: A systematic retrospective analysis of a large group of consecutive patients with definite AIH followed at a tertiary referral centre. J Hepatol 2006; 45: 575-83.
14. Verslype C, George C, Buchel E et al. Diagnosis and treatment of autoimmune hepatitis at age 65 and older. Aliment Pharmacol Ther 2005; 21: 695-9.
15. Newton J, Jones D, Metcalf J et al. Presentation and mortality of primary biliary cirrhosis in older patients. Age Ageing 2000; 29: 305-9.
16. Tischdorf J, Hecker H, Kruger M et al. Characterization, outcome, and prognosis in 273 patients with primary sclerosing cholangitis: A single center study. Am J Gastroenterol 2007; 102: 107-14.
17. Papatheodoridis GV, Manolakopoulos S, Dusheiko G et al. Therapeutic strategies in the management of patients with chronic hepatitis B virus infection. Lancet Infect Dis 2008; 8: 167-78.
18. Kawaoka T, Suzuki F, Akuta N et al. Efficacy of lamivudine therapy in elderly patients with chronic hepatitis B infection. J Gastroenterol 2007; 42: 395-401.
19. Brind A, Watson J, James O et al. Hepatitis C virus infection in the elderly. Q J Med 1996; 89: 291-6.
20. Bresci G, Del Corso L, Romanelli A et al. The use of recombinant interferon alfa-2b in elderly patients with anti-HCV-positive chronic active hepatitis. J Am Geriatr Soc 1993; 41: 857-62.
21. Honda T, Katano Y, Urano F et al. Efficacy of ribavirin plus interferon-alpha in patients aged ≥ 60 years with chronic hepatitis C. Hepatology 2007; 22: 989-95.
22. Monica F, Liruss iF, Pregun I et al. Hepatitis C virus infection in a resident elderly population: A 10-year follow-up study. Dig Liver Dis 2006; 38: 336-40.
23. Collier J, Curless R, Bassendine M et al. Clinical features and prognosis of hepatocellular carcinoma in Britain in relation to age. Age Ageing 1994; 23: 22-7.
24. El-Serag H, Siegel A, Davila J et al. Treatment and outcomes of treating of hepatocellular carcinoma among Medicare recipients in the United States: A population based study. J Hepatol 2006; 44: 158-66.
25. Niederau C, Fischer R, Purschel A et al. Long-term survival in patients with hereditary hemochromatosis [see comment]. Gastroenterology 1996; 110: 1107-19.
26. Roggli VL, Hausner RJ, Askew JB, Jr Alpha-1-antitrypsin globules in hepatocytes of elderly persons with liver disease. Am J Clin Pathol 1981; 75: 538-42.
27. Ross ME, Jacobson IM, Dienstag JL et al. Late-onset Wilson's disease with neurological involvement in the absence of Kayser-Fleischer rings. Ann Neurol 1985; 17: 411-3.
28. Danks DM, Metz G, Sewell R et al. Wilson's disease in adults with cirrhosis but no neurological abnormalities. BMJ 1990; 301: 331-2.
29. Hefter H, Weiss P, Wesch H et al. Late diagnosis of Wilson's disease in a case without onset of symptoms [see comment]. Acta Neurol Scand 1995; 91: 302-5.
30. Kumagi T, Horiike N, Michitaka K et al. Recent clinical features of Wilson's disease with hepatic presentation. J Gastroenterol 2004; 39: 1165-9.