Basal activity of kupffer cells increases with old age

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 62, Issue 9, 2007, Pages 973-978

  Hilmer, Sarah N ^a,b   Cogger, Victoria C ^a   Le Couteur, David G ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b ROYAL NORTH SHORE HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

MICROSPHERE; POLYSTYRENE;

AGE; AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ACTIVITY; CONTROLLED STUDY; IMMUNE RESPONSE; ISOLATED LIVER; KUPFFER CELL; LIVER FUNCTION; LIVER SINUSOID; MICROSCOPY; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; RAT;

RATTUS;

EID: 34948873571     PISSN: 10795006     EISSN: None     Source Type: Journal    
DOI: 10.1093/gerona/62.9.973     Document Type: Article

References (40)

1. Wynne HA, Cope LH, Mutch E, Rawlins MD, Woodhouse KW, James OF. The effect of age upon liver volume and apparent liver blood flow in healthy man. Hepatology. 1989;9:297-301.
2. Le Couteur DG, Cogger VC, Markus AM, et al. Pseudocapillarization and associated energy limitation in the aged rat liver. Hepatology. 2001;33:537-543.
3. Yang MC, McLean AJ, Le Couteur DG. Age-related alteration in hepatic disposition of the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and pesticides. Pharmacol Toxicol. 2002;90:203-207.
4. Hilmer SN, Cogger VC, Fraser R, McLean AJ, Sullivan D, Le Couteur DG. Age-related changes in the hepatic sinusoidal endothelium impede lipoprotein transfer in the rat. Hepatology. 2005;42:1349-1354.
5. Le Couteur DG, Fraser R, Hilmer SN, Rivory LP, McLean AJ. The hepatic sinusoid in aging and cirrhosis: effects on hepatic substrate disposition and drug clearance. Clin Pharmacokinet. 2005;44:187-200.
6. Schmucker DL. Liver function and phase I drug metabolism in the elderly: a paradox. Drugs Aging. 2001;18:837-851.
7. Widmann JJ, Cotran RS, Fahimi HD. Mononuclear phagocytes (Kupffer cells) and endothelial cells. Identification of two functional cell types in rat liver sinusoids by endogenous peroxidase activity. J Cell Biol. 1972;52:159-170.
8. Dan C, Wake K. Modes of endocytosis of latex particles in sinusoidal endothelial and Kupffer cells of normal and perfused rat liver. Exp Cell Res. 1985;158:75-85.
9. Smedsrod B, Johansson S, Pertoft H. Studies in vivo and in vitro on the uptake and degradation of soluble collagen alpha 1(I) chains in rat liver endothelial and Kupffer cells. Biochem J. 1985;228:415-424.
10. Nedredal GI, Elvevold KH, Ytrebo LM, Olsen R, Revhaug A, Smedsrod B. Liver sinusoidal endothelial cells represent an important blood clearance system in pigs. Comp Hepatol. 2003;2:1.
11. Smedsrod B. Clearance function of scavenger endothelial cells. Comp Hepatol. 2004;3 Suppl 1:S22.
12. Ito Y, Bethea NW, McCuskey MK, Sorensen K, Smedsrod B, McCuskey RS. Age-related hepatic microvascular dysfunction in mice. Hepatology. 2005;42:446A.
13. Wisse E. An ultrastructural characterization of the endothelial cell in the rat liver sinusoid under normal and various experimental conditions, as a contribution to the distinction between endothelial and Kupffer cells. J Ultrastruct Res. 1972;38:528-562.
14. Wisse E, Braet F, Luo DZ, et al. Structure and function of sinusoidal lining cells in the liver [review]. Toxicol Pathol. 1996;24:100-111.
15. Naito M, Hasegawa G, Ebe Y, Yamamoto T. Differentiation and function of Kupffer cells. Med Electron Microsc. 2004;37:16-28.
16. Biozzi G, Benacerraf B, Halpern BN. Quantitative study of the granulopectic activity of the reticulo-endothelial system. II. A study of the kinetics of the R. E. S. in relation to the dose of carbon injected; relationship between the weight of the organs and their activity. Br J Exp Pathol. 1953;34:441-457.
17. Ludwig J, Baggenstoss AH. Cirrhosis of the aged and senile cirrhosis - are there two conditions? J Gerontol. 1970;25:244-248.
18. Findor J, Perez V, Igartua EB, Giovanetti M, Fioravantti N. Structure and ultrastructure of the liver in aged persons. Acta Hepato-Gastroenterol. 1973;20:200-204.
19. Ginaldi L, De Martinis M, D'Ostilio A, Marini L, Loreto MF, Quaglino D. Immunological changes in the elderly. Aging (Milano). 1999;11:281-286.
20. Cossarizza A, Ortolani C, Monti D, Franceschi C. Cytometric analysis of imrnunosenescence. Cytometry. 1997;27:297-313.
21. Franceschi C, Bonafe M, Valensin S, et al. Inflamm-aging. An evolutionary perspective on imrnunosenescence. Ann N Y Acad Sci. 2000;908:244-254.
22. Arii S, Imamura M. Physiological role of sinusoidal endothelial cells and Kupffer cells and their implication in the pathogenesis of liver injury. J Hepatobiliary Pancreat Surg. 2000;7:40-48.
23. Wisse E. An electron microscopic study of the fenestrated endothelial lining of rat liver sinusoids. J Ultrastruct Res. 1970;31:125-150.
24. Fraser R, Bosanquet AG, Day WA. Filtration of chylomicrons by the liver may influence cholesterol metabolism and atherosclerosis. Atherosclerosis. 1978;29:113-123.
25. Fraser R, Day WA, Fernando NS. The liver sinusoidal cells. Their role in disorders of the liver, lipoprotein metabolism and atherogenesis. Pathology. 1986;18:5-11.
26. Poste G, Bucana C, Raz A, Bugelski P, Kirsh R, Fidler IJ. Analysis of the fate of systemically administered liposomes and implications for their use in drug delivery. Cancer Res. 1982;42:1412-1422.
27. Romero EL, Morilla MJ, Regts J, Koning GA, Scherphof GL. On the mechanism of hepatic transendothelial passage of large liposomes. FEBS Lett. 1999;448:193-196.
28. Scherphof GL, Kamps JA. The role of hepatocytes in the clearance of liposomes from the blood circulation. Prog Lipid Res. 2001;40:149-166.
29. Wisse E, Gregoriadis G, Daems WT. Electron microscopic cytochemical localization of intravenously injected liposome-encapsulated horseradish peroxidase in rat liver cells. Adv Exp Med Biol. 1976;73:237-245.
30. Rahman YE, Cerny EA, Patel KR, Lau EH, Wright BJ. Differential uptake of liposomes varying in size and lipid composition by parenchymal and Kupffer cells of mouse liver. Life Sci. 1982;31:2061-2071.
31. Cherkasov AN. Selective ultrafiltration. J Membr Sci. 1990;50:109.
32. Watanabe T, Shimada H, Tanaka Y. Human hepatocytes and aging: a cytophotometrical analysis in 35 sudden-death cases. Virchows Arch B Cell Pathol. 1978;27:307-316.
33. Martin G, Sewell RB, Yeomans ND, Smallwood RA. Ageing has no effect on the volume density of hepatocytes, reticulo-endothelial cells or the extracellular space in livers of female Sprague-Dawley rats. Clin Exp Pharmacol Physiol. 1992;19:537-539.
34. Ogawara K, Yoshida M, Higaki K, et al. Hepatic uptake of polystyrene microspheres in rats: effect of particle size on intrahepatic distribution. J Control Release. 1999;59:15-22.
35. Franceschi C, Valensin S, Fagnoni F, Barbi C, Bonafe M. Biomarkers of immunosenescence within an evolutionary perspective: the challenge of heterogeneity and the role of antigenic load. Exp Gerontol. 1999;34:911-921.
36. Videla LA, Tapia G, Fernandez V. Influence of aging on Kupffer cell respiratory activity in relation to particle phagocytosis and oxidative stress parameters in mouse liver. Redox Rep. 2001;6:155-159.
37. Vomel T, Platt D, Schnorr B. Phagocytosis activity of the isolated perfused liver in rats of different ages. Biochemical and ultrastructural examination after perfusion with colloidal ink. [in German] Fortschr Med. 1981;99:1511-1515.
38. Yamano T, DeCicco LA, Rikans LE: Attenuation of cadmium-induced liver injury in senescent male Fischer 344 rats: role of Kupffer cells and inflammatory cytokines. Toxicol Appl Pharmacol. 2000;162:68-75.
39. Fujita H, Kawamata S, Yamashita K. Electron microscopic studies on multinucleate foreign body giant cells derived from Kupffer cells in mice given Indian ink intravenously. Virchows Arch B Cell Pathol Incl Mol Pathol. 1983;42:33-42.
40. Gomez CR, Acuna-Castillo C, Nishimura S, et al. Serum from aged F344 rats conditions the activation of young macrophages. Mech Ageing Dev. 2006;127:257-263.