E177-E186 TANK-binding kinase 1 (TBK1) controls cell survival through PAI-2/serpinB2 and transglutaminase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 4, 2012, Pages

  Delhase, Mireille ^a,b,c,d   Kim, Soo Youl ^e   Lee, Ho ^f   Naiki Ito, Aya ^d   Chen, Yi ^c,g   Ahn, Eu Ree ^e   Murata, Kazuhiro ^d   Kim, Se Jin ^e   Lautsch, Norman ^a,h   Kobayashi, Koichi S ^a,b   Shirai, Tomoyuki ^d   Karin, Michael ^c   Nakanishi, Makoto ^d  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^e National Cancer Center   (South Korea)

^f National Cancer Center   (South Korea)

^g Shanghai Kanda Biotechnology   (China)

^h JOSLIN DIABETES CENTER   (United States)

Author keywords

Apoptosis; Posttranslational protein modification; Transcriptional regulation; Tumor necrosis factor signaling

Indexed keywords

BINDING PROTEIN; CASPASE 3; CASPASE 8; PLASMINOGEN ACTIVATOR INHIBITOR 2; PROCASPASE 3; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE 2; SYNAPTOTAGMIN I; TANK BINDING KINASE 1; UNCLASSIFIED DRUG; COMPLEMENTARY DNA; GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; PROTEIN SERINE THREONINE KINASE; RELA PROTEIN, MOUSE; SMALL INTERFERING RNA; TBK1 PROTEIN, MOUSE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; GENE EXPRESSION; LIVER CELL; LIVER INJURY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; ANIMAL; AUTORADIOGRAPHY; CHROMATIN IMMUNOPRECIPITATION; FLUORESCENT ANTIBODY TECHNIQUE; GENE SILENCING; GENETIC TRANSDUCTION; GENETICS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; METABOLISM; MICROARRAY ANALYSIS; MOUSE MUTANT; NICK END LABELING; PHOSPHORYLATION; PHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; REAL TIME POLYMERASE CHAIN REACTION; SITE DIRECTED MUTAGENESIS;

MUS;

ANIMALS; APOPTOSIS; AUTORADIOGRAPHY; CASPASE 3; CELL SURVIVAL; CHROMATIN IMMUNOPRECIPITATION; DNA, COMPLEMENTARY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FLUORESCENT ANTIBODY TECHNIQUE; GENE SILENCING; GTP-BINDING PROTEINS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; IN SITU NICK-END LABELING; MICE; MICE, KNOCKOUT; MICROARRAY ANALYSIS; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; PLASMINOGEN ACTIVATOR INHIBITOR 2; PROTEIN-SERINE-THREONINE KINASES; REAL-TIME POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; TRANSCRIPTION FACTOR RELA; TRANSDUCTION, GENETIC; TRANSGLUTAMINASES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84856387483     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1119296109     Document Type: Article

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