-
1
-
-
0035823595
-
The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature
-
Silverman, G. A., Bird, P. I., Carrell, R. W., Church, F. C., Coughlin, P. B., Gettins, P. G., Irving, J. A., Lomas, D. A., Luke, C. J., Moyer, R. W., Pemberton, P. A., Remold-O'Donnell, E., Salvesen, G. S., Travis, J. and Whisstock, J. C. (2001) The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature. J. Biol. Chem. 276, 33293-33296.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 33293-33296
-
-
Silverman, G.A.1
Bird, P.I.2
Carrell, R.W.3
Church, F.C.4
Coughlin, P.B.5
Gettins, P.G.6
Irving, J.A.7
Lomas, D.A.8
Luke, C.J.9
Moyer, R.W.10
Pemberton, P.A.11
Remold-O'Donnell, E.12
Salvesen, G.S.13
Travis, J.14
Whisstock, J.C.15
-
2
-
-
0036882395
-
Serpin structure, mechanism, and function
-
Gettins, P. G. (2002) Serpin structure, mechanism, and function. Chem. Rev. 102, 4751-4804.
-
(2002)
Chem. Rev
, vol.102
, pp. 4751-4804
-
-
Gettins, P.G.1
-
3
-
-
1242298756
-
Human clade B serpins (ov-serpins) belong to a cohort of evolutionarily dispersed intracellular proteinase inhibitor clades that protect cells from promiscuous proteolysis
-
Silverman, G. A., Whisstock, J. C., Askew, D. J., Pak, S. C., Luke, C. J., Cataltepe, S., Irving, J. A. and Bird, P. I. (2004) Human clade B serpins (ov-serpins) belong to a cohort of evolutionarily dispersed intracellular proteinase inhibitor clades that protect cells from promiscuous proteolysis. Cell. Mol. Life. Sci. 61, 301-325.
-
(2004)
Cell. Mol. Life. Sci
, vol.61
, pp. 301-325
-
-
Silverman, G.A.1
Whisstock, J.C.2
Askew, D.J.3
Pak, S.C.4
Luke, C.J.5
Cataltepe, S.6
Irving, J.A.7
Bird, P.I.8
-
4
-
-
0027393310
-
The ovalbumin family of serpin proteins
-
Remold-O'Donnell, E. (1993) The ovalbumin family of serpin proteins. FEBS Lett. 315, 105-108.
-
(1993)
FEBS Lett
, vol.315
, pp. 105-108
-
-
Remold-O'Donnell, E.1
-
5
-
-
2442485932
-
SRP-2 is a cross-class inhibitor that participates in postembryonic development of the nematode Caenorhabditis elegans: Initial characterization of the clade L serpins
-
Pak, S. C., Kumar, V., Tsu, C., Luke, C. J., Askew, Y. S., Askew, D. J., Mills, D. R., Bromme, D. and Silverman, G. A. (2004) SRP-2 is a cross-class inhibitor that participates in postembryonic development of the nematode Caenorhabditis elegans: initial characterization of the clade L serpins. J. Biol. Chem. 279, 15448-15459.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 15448-15459
-
-
Pak, S.C.1
Kumar, V.2
Tsu, C.3
Luke, C.J.4
Askew, Y.S.5
Askew, D.J.6
Mills, D.R.7
Bromme, D.8
Silverman, G.A.9
-
6
-
-
23844473263
-
The ovalbumin serpins revisited: Perspective from the chicken genome of clade B serpin evolution in vertebrates
-
Benarafa, C. and Remold-O'Donnell, E. (2005) The ovalbumin serpins revisited: perspective from the chicken genome of clade B serpin evolution in vertebrates. Proc. Natl. Acad. Sci. USA 102, 11367-11372.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 11367-11372
-
-
Benarafa, C.1
Remold-O'Donnell, E.2
-
7
-
-
0028987729
-
Chromosomal mapping of the human proteinase inhibitor 6 (PI6) gene to 6p25 by fluorescence in situ hybridization
-
Coughlin, P., Nicholl, J., Sun, J., Salem, H., Bird, P. and Sutherland, G. R. (1995) Chromosomal mapping of the human proteinase inhibitor 6 (PI6) gene to 6p25 by fluorescence in situ hybridization. Genomics 26, 431-433.
-
(1995)
Genomics
, vol.26
, pp. 431-433
-
-
Coughlin, P.1
Nicholl, J.2
Sun, J.3
Salem, H.4
Bird, P.5
Sutherland, G.R.6
-
8
-
-
0029164875
-
Characterization and chromosomal localization of ELANH2, the gene encoding human monocyte/neutrophil elastase inhibitor
-
Evans, E., Cooley, J. and Remold-O'Donnell, E. (1995) Characterization and chromosomal localization of ELANH2, the gene encoding human monocyte/neutrophil elastase inhibitor. Genomics 28, 235-240.
-
(1995)
Genomics
, vol.28
, pp. 235-240
-
-
Evans, E.1
Cooley, J.2
Remold-O'Donnell, E.3
-
9
-
-
0030298238
-
Chromosomal mapping of the gene (PI9) encoding the intracellular serpin proteinase inhibitor 9 to 6p25 by fluorescence in situ hybridization
-
Eyre, H. J., Sun, J., Sutherland, G. R. and Bird, P. (1996) Chromosomal mapping of the gene (PI9) encoding the intracellular serpin proteinase inhibitor 9 to 6p25 by fluorescence in situ hybridization. Genomics 37, 406-408.
-
(1996)
Genomics
, vol.37
, pp. 406-408
-
-
Eyre, H.J.1
Sun, J.2
Sutherland, G.R.3
Bird, P.4
-
10
-
-
0035966087
-
SERPINB12 is a novel member of the human ov-serpin family that is widely expressed and inhibits trypsin-like serine proteinases
-
Askew, Y. S., Pak, S. C., Luke, C. J., Askew, D. J., Cataltepe, S., Mills, D. R., Kato, H., Lehoczky, J., Dewar, K., Birren, B. and Silverman, G. A. (2001) SERPINB12 is a novel member of the human ov-serpin family that is widely expressed and inhibits trypsin-like serine proteinases. J. Biol. Chem. 276, 49320-49330.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 49320-49330
-
-
Askew, Y.S.1
Pak, S.C.2
Luke, C.J.3
Askew, D.J.4
Cataltepe, S.5
Mills, D.R.6
Kato, H.7
Lehoczky, J.8
Dewar, K.9
Birren, B.10
Silverman, G.A.11
-
11
-
-
0031214562
-
Cytoplasmic antiproteinase 2 (PI8) and bomapin (PI10) map to the serpin cluster at 18q21.3
-
Bartuski, A. J., Kamachi, Y., Schick, C., Overhauser, J. and Silverman, G. A. (1997) Cytoplasmic antiproteinase 2 (PI8) and bomapin (PI10) map to the serpin cluster at 18q21.3. Genomics 43, 321-328.
-
(1997)
Genomics
, vol.43
, pp. 321-328
-
-
Bartuski, A.J.1
Kamachi, Y.2
Schick, C.3
Overhauser, J.4
Silverman, G.A.5
-
12
-
-
0036200071
-
Comparison of human chromosome 6p25 with mouse chromosome 13 reveals a greatly expanded ov-serpin gene repertoire in the mouse
-
Kaiserman, D., Knaggs, S., Scarff, K. L., Gillard, A., Mirza, G., Cadman, M., McKeone, R., Denny, P., Cooley, J., Benarafa, C., Remold-O'Donnell, E., Ragoussis, J. and Bird, P. I. (2002) Comparison of human chromosome 6p25 with mouse chromosome 13 reveals a greatly expanded ov-serpin gene repertoire in the mouse. Genomics 79, 349-362.
-
(2002)
Genomics
, vol.79
, pp. 349-362
-
-
Kaiserman, D.1
Knaggs, S.2
Scarff, K.L.3
Gillard, A.4
Mirza, G.5
Cadman, M.6
McKeone, R.7
Denny, P.8
Cooley, J.9
Benarafa, C.10
Remold-O'Donnell, E.11
Ragoussis, J.12
Bird, P.I.13
-
13
-
-
0347445722
-
A genomic analysis of rat proteases and protease inhibitors
-
Puente, X. S. and Lopez-Otin, C. (2004) A genomic analysis of rat proteases and protease inhibitors. Genome Res. 14, 609-622.
-
(2004)
Genome Res
, vol.14
, pp. 609-622
-
-
Puente, X.S.1
Lopez-Otin, C.2
-
14
-
-
2942625830
-
Comparative genomic analysis of the clade B serpin cluster at human chromosome 18q21: Amplification within the mouse squamous cell carcinoma antigen gene locus
-
Askew, D. J., Askew, Y. S., Kato, Y., Turner, R. F., Dewar, K., Lehoczky, J. and Silverman, G. A. (2004) Comparative genomic analysis of the clade B serpin cluster at human chromosome 18q21: amplification within the mouse squamous cell carcinoma antigen gene locus. Genomics 84, 176-184.
-
(2004)
Genomics
, vol.84
, pp. 176-184
-
-
Askew, D.J.1
Askew, Y.S.2
Kato, Y.3
Turner, R.F.4
Dewar, K.5
Lehoczky, J.6
Silverman, G.A.7
-
15
-
-
28544440426
-
Analysis of vertebrate genomes suggests a new model for clade B serpin evolution
-
Kaiserman, D. and Bird, P. I. (2005) Analysis of vertebrate genomes suggests a new model for clade B serpin evolution. BMC Genomics 6, 167.
-
(2005)
BMC Genomics
, vol.6
, pp. 167
-
-
Kaiserman, D.1
Bird, P.I.2
-
16
-
-
0024430428
-
Ovalbumin and angiotensinogen lack serpin S-R conformational change
-
Stein, P. E., Tewkesbury, D. A. and Carrell, R. W. (1989) Ovalbumin and angiotensinogen lack serpin S-R conformational change. Biochem. J. 262, 103-107.
-
(1989)
Biochem. J
, vol.262
, pp. 103-107
-
-
Stein, P.E.1
Tewkesbury, D.A.2
Carrell, R.W.3
-
17
-
-
0028803776
-
Pigment epithelium-derived factor behaves like a noninhibitory serpin. Neurotrophic activity does not require the serpin reactive loop
-
Becerra, S. P., Sagasti, A., Spinella, P. and Notario, V. (1995) Pigment epithelium-derived factor behaves like a noninhibitory serpin. Neurotrophic activity does not require the serpin reactive loop. J. Biol. Chem. 270, 25992-25999.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 25992-25999
-
-
Becerra, S.P.1
Sagasti, A.2
Spinella, P.3
Notario, V.4
-
18
-
-
0028090118
-
Function of maspin
-
Hopkins, P. C. and Whisstock, J. (1994) Function of maspin. Science 265, 1893-1894.
-
(1994)
Science
, vol.265
, pp. 1893-1894
-
-
Hopkins, P.C.1
Whisstock, J.2
-
19
-
-
34548349300
-
SERPINB11 is a new noninhibitory intracellular serpin. Common single nucleotide polymorphisms in the scaffold impair conformational change
-
Askew, D. J., Cataltepe, S., Kumar, V., Edwards, C., Pace, S. M., Howarth, R. N., Pak, S. C., Askew, Y. S., Bromme, D., Luke, C. J., Whisstock, J. C. and Silverman, G. A. (2007) SERPINB11 is a new noninhibitory intracellular serpin. Common single nucleotide polymorphisms in the scaffold impair conformational change. J. Biol. Chem. 282, 24948-24960.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 24948-24960
-
-
Askew, D.J.1
Cataltepe, S.2
Kumar, V.3
Edwards, C.4
Pace, S.M.5
Howarth, R.N.6
Pak, S.C.7
Askew, Y.S.8
Bromme, D.9
Luke, C.J.10
Whisstock, J.C.11
Silverman, G.A.12
-
20
-
-
0029058971
-
The tumor suppressor maspin does not undergo the stressed to relaxed transition or inhibit trypsin-like serine proteases. Evidence that maspin is not a protease inhibitory serpin
-
Pemberton, P. A., Wong, D. T., Gibson, H. L., Kiefer, M. C., Fitzpatrick, P. A., Sager, R. and Barr, P. J. (1995) The tumor suppressor maspin does not undergo the stressed to relaxed transition or inhibit trypsin-like serine proteases. Evidence that maspin is not a protease inhibitory serpin. J. Biol. Chem. 270, 15832-15837.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 15832-15837
-
-
Pemberton, P.A.1
Wong, D.T.2
Gibson, H.L.3
Kiefer, M.C.4
Fitzpatrick, P.A.5
Sager, R.6
Barr, P.J.7
-
21
-
-
11244315121
-
Crystal structure of human maspin, a serpin with antitumor properties: Reactive center loop of maspin is exposed but constrained
-
Al-Ayyoubi, M., Gettins, P. G. and Volz, K. (2004) Crystal structure of human maspin, a serpin with antitumor properties: reactive center loop of maspin is exposed but constrained. J. Biol. Chem. 279, 55540-55544.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 55540-55544
-
-
Al-Ayyoubi, M.1
Gettins, P.G.2
Volz, K.3
-
22
-
-
20444488806
-
The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix
-
Law, R. H., Irving, J. A., Buckle, A. M., Ruzyla, K., Buzza, M., Bashtannyk-Puhalovich, T. A., Beddoe, T. C., Nguyen, K., Worrall, D. M., Bottomley, S. P., Bird, P. I., Rossjohn, J. and Whisstock, J. C. (2005) The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix. J. Biol. Chem. 280, 22356-22364.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 22356-22364
-
-
Law, R.H.1
Irving, J.A.2
Buckle, A.M.3
Ruzyla, K.4
Buzza, M.5
Bashtannyk-Puhalovich, T.A.6
Beddoe, T.C.7
Nguyen, K.8
Worrall, D.M.9
Bottomley, S.P.10
Bird, P.I.11
Rossjohn, J.12
Whisstock, J.C.13
-
23
-
-
0025003236
-
Crystal structure of ovalbumin as a model for the reactive centre of serpins
-
Stein, P. E., Leslie, A. G., Finch, J. T., Turnell, W. G., McLaughlin, P. J. and Carrell, R. W. (1990) Crystal structure of ovalbumin as a model for the reactive centre of serpins. Nature 347, 99-102.
-
(1990)
Nature
, vol.347
, pp. 99-102
-
-
Stein, P.E.1
Leslie, A.G.2
Finch, J.T.3
Turnell, W.G.4
McLaughlin, P.J.5
Carrell, R.W.6
-
24
-
-
0035949561
-
Crystal structure of human PEDF, a potent anti-angiogenic and neurite growth-promoting factor
-
Simonovic, M., Gettins, P. G. and Volz, K. (2001) Crystal structure of human PEDF, a potent anti-angiogenic and neurite growth-promoting factor. Proc. Natl. Acad. Sci. USA 98, 11131-11135.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 11131-11135
-
-
Simonovic, M.1
Gettins, P.G.2
Volz, K.3
-
25
-
-
0028168514
-
Inhibition of interleukin-1β converting enzyme by the cowpox virus serpin CrmA. An example of cross-class inhibition
-
Komiyama, T., Ray, C. A., Pickup, D. J., Howard, A. D., Thornberry, N. A., Peterson, E. P. and Salvesen, G. (1994) Inhibition of interleukin-1β converting enzyme by the cowpox virus serpin CrmA. An example of cross-class inhibition. J. Biol. Chem. 269, 19331-19337.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 19331-19337
-
-
Komiyama, T.1
Ray, C.A.2
Pickup, D.J.3
Howard, A.D.4
Thornberry, N.A.5
Peterson, E.P.6
Salvesen, G.7
-
26
-
-
0030479333
-
Pepsin-inhibitory activity of the uterine serpins
-
Mathialagan, N. and Hansen, T. R. (1996) Pepsin-inhibitory activity of the uterine serpins. Proc. Natl. Acad. Sci. USA 93, 13653-13658.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 13653-13658
-
-
Mathialagan, N.1
Hansen, T.R.2
-
27
-
-
0030977847
-
Target protease specificity of the viral serpin CrmA. Analysis of five caspases
-
Zhou, Q., Snipas, S., Orth, K., Muzio, M., Dixit, V. M. and Salvesen, G. S. (1997) Target protease specificity of the viral serpin CrmA. Analysis of five caspases. J. Biol. Chem. 272, 7797-7800.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 7797-7800
-
-
Zhou, Q.1
Snipas, S.2
Orth, K.3
Muzio, M.4
Dixit, V.M.5
Salvesen, G.S.6
-
28
-
-
0028955325
-
Granzyme B is inhibited by the cowpox virus serpin cytokine response modifier A
-
Quan, L. T., Caputo, A., Bleackley, R. C., Pickup, D. J. and Salvesen, G. S. (1995) Granzyme B is inhibited by the cowpox virus serpin cytokine response modifier A. J. Biol. Chem. 270, 10377-10379.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 10377-10379
-
-
Quan, L.T.1
Caputo, A.2
Bleackley, R.C.3
Pickup, D.J.4
Salvesen, G.S.5
-
29
-
-
0028814981
-
Squamous cell carcinoma antigen is a potent inhibitor of cysteine proteinase cathepsin L
-
Takeda, A., Yamamoto, T., Nakamura, Y., Takahashi, T. and Hibino, T. (1995) Squamous cell carcinoma antigen is a potent inhibitor of cysteine proteinase cathepsin L. FEBS Lett. 359, 78-80.
-
(1995)
FEBS Lett
, vol.359
, pp. 78-80
-
-
Takeda, A.1
Yamamoto, T.2
Nakamura, Y.3
Takahashi, T.4
Hibino, T.5
-
30
-
-
0032515939
-
Cross-class inhibition of the cysteine proteinases cathepsins K, L, and S by the serpin squamous cell carcinoma antigen 1: A kinetic analysis
-
Schick, C., Pemberton, P. A., Shi, G. P., Kamachi, Y., Cataltepe, S., Bartuski, A. J., Gornstein, E. R., Bromme, D., Chapman, H. A. and Silverman, G. A. (1998) Cross-class inhibition of the cysteine proteinases cathepsins K, L, and S by the serpin squamous cell carcinoma antigen 1: a kinetic analysis. Biochemistry 37, 5258-5266.
-
(1998)
Biochemistry
, vol.37
, pp. 5258-5266
-
-
Schick, C.1
Pemberton, P.A.2
Shi, G.P.3
Kamachi, Y.4
Cataltepe, S.5
Bartuski, A.J.6
Gornstein, E.R.7
Bromme, D.8
Chapman, H.A.9
Silverman, G.A.10
-
31
-
-
0033568456
-
Caspase-1 (interleukin-1β-converting enzyme) is inhibited by the human serpin analogue proteinase inhibitor 9
-
Annand, R. R., Dahlen, J. R., Sprecher, C. A., De Dreu, P., Foster, D. C., Mankovich, J. A., Talanian, R. V., Kisiel, W. and Giegel, D. A. (1999) Caspase-1 (interleukin-1β-converting enzyme) is inhibited by the human serpin analogue proteinase inhibitor 9. Biochem. J. 342, 655-665.
-
(1999)
Biochem. J
, vol.342
, pp. 655-665
-
-
Annand, R.R.1
Dahlen, J.R.2
Sprecher, C.A.3
De Dreu, P.4
Foster, D.C.5
Mankovich, J.A.6
Talanian, R.V.7
Kisiel, W.8
Giegel, D.A.9
-
32
-
-
34447635084
-
Ectopic expression of the serine protease inhibitor PI9 modulates death receptor-mediated apoptosis
-
Kummer, J. A., Micheau, O., Schneider, P., Bovenschen, N., Broekhuizen, R., Quadir, R., Strik, M. C., Hack, C. E. and Tschopp, J. (2007) Ectopic expression of the serine protease inhibitor PI9 modulates death receptor-mediated apoptosis. Cell Death Differ. 14, 1486-1496.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1486-1496
-
-
Kummer, J.A.1
Micheau, O.2
Schneider, P.3
Bovenschen, N.4
Broekhuizen, R.5
Quadir, R.6
Strik, M.C.7
Hack, C.E.8
Tschopp, J.9
-
33
-
-
0029914132
-
A cytosolic granzyme B inhibitor related to the viral apoptotic regulator cytokine response modifier A is present in cytotoxic lymphocytes
-
Sun, J., Bird, C. H., Sutton, V., McDonald, L., Coughlin, P. B., De Jong, T. A., Trapani, J. A. and Bird, P. I. (1996) A cytosolic granzyme B inhibitor related to the viral apoptotic regulator cytokine response modifier A is present in cytotoxic lymphocytes. J. Biol. Chem. 271, 27802-27809.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 27802-27809
-
-
Sun, J.1
Bird, C.H.2
Sutton, V.3
McDonald, L.4
Coughlin, P.B.5
De Jong, T.A.6
Trapani, J.A.7
Bird, P.I.8
-
34
-
-
0038408712
-
Hurpin is a selective inhibitor of lysosomal cathepsin L and protects keratinocytes from ultraviolet-induced apoptosis
-
Welss, T., Sun, J., Irving, J. A., Blum, R., Smith, A. I., Whisstock, J. C., Pike, R. N., von Mikecz, A., Ruzicka, T., Bird, P. I. and Abts, H. F. (2003) Hurpin is a selective inhibitor of lysosomal cathepsin L and protects keratinocytes from ultraviolet-induced apoptosis. Biochemistry 42, 7381-7389.
-
(2003)
Biochemistry
, vol.42
, pp. 7381-7389
-
-
Welss, T.1
Sun, J.2
Irving, J.A.3
Blum, R.4
Smith, A.I.5
Whisstock, J.C.6
Pike, R.N.7
von Mikecz, A.8
Ruzicka, T.9
Bird, P.I.10
Abts, H.F.11
-
35
-
-
0037440423
-
Inhibition of the cysteine proteinases cathepsins K and L by the serpin headpin (SERPINB13): A kinetic analysis
-
Jayakumar, A., Kang, Y., Frederick, M. J., Pak, S. C., Henderson, Y., Holton, P. R., Mitsudo, K., Silverman, G. A., EL-Naggar, A. K., Brömme, D. and Clayman, G. L. (2003) Inhibition of the cysteine proteinases cathepsins K and L by the serpin headpin (SERPINB13): a kinetic analysis. Arch. Biochem. Biophys. 409, 367-374.
-
(2003)
Arch. Biochem. Biophys
, vol.409
, pp. 367-374
-
-
Jayakumar, A.1
Kang, Y.2
Frederick, M.J.3
Pak, S.C.4
Henderson, Y.5
Holton, P.R.6
Mitsudo, K.7
Silverman, G.A.8
EL-Naggar, A.K.9
Brömme, D.10
Clayman, G.L.11
-
36
-
-
10744220160
-
The squamous cell carcinoma antigen 2 inhibits the cysteine proteinase activity of a major mite allergen, Der p 1
-
Sakata, Y., Arima, K., Takai, T., Sakurai, W., Masumoto, K., Yuyama, N., Suminami, Y., Kishi, F., Yamashita, T., Kato, T., Ogawa, H., Fujimoto, K., Matsuo, Y., Sugita, Y. and Izuhara, K. (2004) The squamous cell carcinoma antigen 2 inhibits the cysteine proteinase activity of a major mite allergen, Der p 1. J. Biol. Chem. 279, 5081-5087.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 5081-5087
-
-
Sakata, Y.1
Arima, K.2
Takai, T.3
Sakurai, W.4
Masumoto, K.5
Yuyama, N.6
Suminami, Y.7
Kishi, F.8
Yamashita, T.9
Kato, T.10
Ogawa, H.11
Fujimoto, K.12
Matsuo, Y.13
Sugita, Y.14
Izuhara, K.15
-
37
-
-
0035692792
-
Serpins and other covalent protease inhibitors
-
Ye, S. and Goldsmith, E. J. (2001) Serpins and other covalent protease inhibitors. Curr. Opin. Struct. Biol. 11, 740-745.
-
(2001)
Curr. Opin. Struct. Biol
, vol.11
, pp. 740-745
-
-
Ye, S.1
Goldsmith, E.J.2
-
38
-
-
0034687422
-
Structure of a serpin-protease complex shows inhibition by deformation
-
Huntington, J. A., Read, R. J. and Carrell, R. W. (2000) Structure of a serpin-protease complex shows inhibition by deformation. Nature 407, 923-926.
-
(2000)
Nature
, vol.407
, pp. 923-926
-
-
Huntington, J.A.1
Read, R.J.2
Carrell, R.W.3
-
39
-
-
0242580990
-
Inhibitory mechanism of a cross-class serpin, the squamous cell carcinoma antigen 1
-
Masumoto, K., Sakata, Y., Arima, K., Nakao, I. and Izuhara, K. (2003) Inhibitory mechanism of a cross-class serpin, the squamous cell carcinoma antigen 1. J. Biol. Chem. 278, 45296-45304.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 45296-45304
-
-
Masumoto, K.1
Sakata, Y.2
Arima, K.3
Nakao, I.4
Izuhara, K.5
-
40
-
-
0037066736
-
Inhibitory activity of a heterochromatin-associated serpin (MENT) against papain-like cysteine proteinases affects chromatin structure and blocks cell proliferation
-
Irving, J. A., Shushanov, S. S., Pike, R. N., Popova, E. Y., Bromme, D., Coetzer, T. H., Bottomley, S. P., Boulynko, I. A., Grigoryev, S. A. and Whisstock, J. C. (2002) Inhibitory activity of a heterochromatin-associated serpin (MENT) against papain-like cysteine proteinases affects chromatin structure and blocks cell proliferation. J. Biol. Chem. 277, 13192-13201.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 13192-13201
-
-
Irving, J.A.1
Shushanov, S.S.2
Pike, R.N.3
Popova, E.Y.4
Bromme, D.5
Coetzer, T.H.6
Bottomley, S.P.7
Boulynko, I.A.8
Grigoryev, S.A.9
Whisstock, J.C.10
-
41
-
-
0037143531
-
The novel serpin endopin 2 demonstrates cross-class inhibition of papain and elastase: Localization of endopin 2 to regulated secretory vesicles of neuroendocrine chromaffin cells
-
Hwang, S. R., Steineckert, B., Toneff, T., Bundey, R., Logvinova, A. V., Goldsmith, P. and Hook, V. Y. (2002) The novel serpin endopin 2 demonstrates cross-class inhibition of papain and elastase: localization of endopin 2 to regulated secretory vesicles of neuroendocrine chromaffin cells. Biochemistry 41, 10397-10405.
-
(2002)
Biochemistry
, vol.41
, pp. 10397-10405
-
-
Hwang, S.R.1
Steineckert, B.2
Toneff, T.3
Bundey, R.4
Logvinova, A.V.5
Goldsmith, P.6
Hook, V.Y.7
-
42
-
-
19644394871
-
The novel bovine serpin endopin 2C demonstrates selective inhibition of the cysteine protease cathepsin L compared to the serine protease elastase, in cross-class inhibition
-
Hwang, S. R., Stoka, V., Turk, V. and Hook, V. Y. (2005) The novel bovine serpin endopin 2C demonstrates selective inhibition of the cysteine protease cathepsin L compared to the serine protease elastase, in cross-class inhibition. Biochemistry 44, 7757-7767.
-
(2005)
Biochemistry
, vol.44
, pp. 7757-7767
-
-
Hwang, S.R.1
Stoka, V.2
Turk, V.3
Hook, V.Y.4
-
43
-
-
34548153043
-
Squamous cell carcinoma antigen 1 is an inhibitor of parasite-derived cysteine proteases
-
Kanaji, S., Tanaka, Y., Sakata, Y., Takeshita, K., Arima, K., Ohta, S., Hansell, E. J., Caffrey, C., Mottram, J. C., Lowther, J., Donnelly, S., Stack, C., Kadowaki, T., Yamamoto, K., McKerrow, J. H., Dalton, J. P., Coombs, G. H. and Izuhara, K. (2007) Squamous cell carcinoma antigen 1 is an inhibitor of parasite-derived cysteine proteases. FEBS Lett. 581, 4260-4264.
-
(2007)
FEBS Lett
, vol.581
, pp. 4260-4264
-
-
Kanaji, S.1
Tanaka, Y.2
Sakata, Y.3
Takeshita, K.4
Arima, K.5
Ohta, S.6
Hansell, E.J.7
Caffrey, C.8
Mottram, J.C.9
Lowther, J.10
Donnelly, S.11
Stack, C.12
Kadowaki, T.13
Yamamoto, K.14
McKerrow, J.H.15
Dalton, J.P.16
Coombs, G.H.17
Izuhara, K.18
-
44
-
-
0033574684
-
Identification of a nuclear targeting domain in the insertion between helices C and D in protease inhibitor-10
-
Chuang, T. L. and Schleef, R. R. (1999) Identification of a nuclear targeting domain in the insertion between helices C and D in protease inhibitor-10. J. Biol. Chem. 274, 11194-11198.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 11194-11198
-
-
Chuang, T.L.1
Schleef, R.R.2
-
45
-
-
0034932940
-
Nucleocytoplasmic distribution of the ovalbumin serpin PI-9 requires a nonconventional nuclear import pathway and the export factor Crm1
-
Bird, C. H., Blink, E. J., Hirst, C. E., Buzza, M. S., Steele, P. M., Sun, J., Jans, D. A. and Bird, P. I. (2001) Nucleocytoplasmic distribution of the ovalbumin serpin PI-9 requires a nonconventional nuclear import pathway and the export factor Crm1. Mol. Cell. Biol. 21, 5396-5407.
-
(2001)
Mol. Cell. Biol
, vol.21
, pp. 5396-5407
-
-
Bird, C.H.1
Blink, E.J.2
Hirst, C.E.3
Buzza, M.S.4
Steele, P.M.5
Sun, J.6
Jans, D.A.7
Bird, P.I.8
-
46
-
-
0036868046
-
Distribution of the human intracellular serpin protease inhibitor 8 in human tissues
-
Strik, M. C., Bladergroen, B. A., Wouters, D., Kisiel, W., Hooijberg, J. H., Verlaan, A. R., Hordijk, P. L., Schneider, P., Hack, C. E. and Kummer, J. A. (2002) Distribution of the human intracellular serpin protease inhibitor 8 in human tissues. J. Histochem. Cytochem. 50, 1443-1454.
-
(2002)
J. Histochem. Cytochem
, vol.50
, pp. 1443-1454
-
-
Strik, M.C.1
Bladergroen, B.A.2
Wouters, D.3
Kisiel, W.4
Hooijberg, J.H.5
Verlaan, A.R.6
Hordijk, P.L.7
Schneider, P.8
Hack, C.E.9
Kummer, J.A.10
-
47
-
-
0014760451
-
Partial purification and properties of urokinase inhibitor from human placenta
-
Kawano, T., Morimoto, K. and Uemura, Y. (1970) Partial purification and properties of urokinase inhibitor from human placenta. J. Biochem. 67, 333-342.
-
(1970)
J. Biochem
, vol.67
, pp. 333-342
-
-
Kawano, T.1
Morimoto, K.2
Uemura, Y.3
-
48
-
-
26244444789
-
The undecided serpin. The ins and outs of plasminogen activator inhibitor type 2
-
Medcalf, R. L. and Stasinopoulos, S. J. (2005) The undecided serpin. The ins and outs of plasminogen activator inhibitor type 2. FEBS J. 272, 4858-4867.
-
(2005)
FEBS J
, vol.272
, pp. 4858-4867
-
-
Medcalf, R.L.1
Stasinopoulos, S.J.2
-
49
-
-
0028787122
-
Biological and clinical aspects of plasminogen activator inhibitor type 2
-
Kruithof, E. K., Baker, M. S. and Bunn, C. L. (1995) Biological and clinical aspects of plasminogen activator inhibitor type 2. Blood 86, 4007-4024.
-
(1995)
Blood
, vol.86
, pp. 4007-4024
-
-
Kruithof, E.K.1
Baker, M.S.2
Bunn, C.L.3
-
50
-
-
0023149587
-
Fibrinolysis in pregnancy: A study of plasminogen activator inhibitors
-
Kruithof, E. K., Tran-Thang, C., Gudinchet, A., Hauert, J., Nicoloso, G., Genton, C., Welti, H. and Bachmann, F. (1987) Fibrinolysis in pregnancy: a study of plasminogen activator inhibitors. Blood 69, 460-466.
-
(1987)
Blood
, vol.69
, pp. 460-466
-
-
Kruithof, E.K.1
Tran-Thang, C.2
Gudinchet, A.3
Hauert, J.4
Nicoloso, G.5
Genton, C.6
Welti, H.7
Bachmann, F.8
-
51
-
-
0032929389
-
Suppression of keratinocyte proliferation by plasminogen activator inhibitor-2
-
Hibino, T., Matsuda, Y., Takahashi, T. and Goetinck, P. F. (1999) Suppression of keratinocyte proliferation by plasminogen activator inhibitor-2. J. Invest. Dermatol. 112, 85-90.
-
(1999)
J. Invest. Dermatol
, vol.112
, pp. 85-90
-
-
Hibino, T.1
Matsuda, Y.2
Takahashi, T.3
Goetinck, P.F.4
-
52
-
-
0023637406
-
Plasminogen activator inhibitor 2: Regulation of gene transcription during phorbol ester-mediated differentiation of U-937 human histiocytic lymphoma cells
-
Schleuning, W. D., Medcalf, R. L., Hession, C., Rothenbuhler, R., Shaw, A. and Kruithof, E. K. (1987) Plasminogen activator inhibitor 2: regulation of gene transcription during phorbol ester-mediated differentiation of U-937 human histiocytic lymphoma cells. Mol. Cell. Biol. 7, 4564-4567.
-
(1987)
Mol. Cell. Biol
, vol.7
, pp. 4564-4567
-
-
Schleuning, W.D.1
Medcalf, R.L.2
Hession, C.3
Rothenbuhler, R.4
Shaw, A.5
Kruithof, E.K.6
-
53
-
-
0032101523
-
The serine proteinase inhibitor (serpin) plasminogen activation inhibitor type 2 protects against viral cytopathic effects by constitutive interferon α/β priming
-
Antalis, T. M., La Linn, M., Donnan, K., Mateo, L., Gardner, J., Dickinson, J. L., Buttigieg, K. and Suhrbier, A. (1998) The serine proteinase inhibitor (serpin) plasminogen activation inhibitor type 2 protects against viral cytopathic effects by constitutive interferon α/β priming. J. Exp. Med. 187, 1799-1811.
-
(1998)
J. Exp. Med
, vol.187
, pp. 1799-1811
-
-
Antalis, T.M.1
La Linn, M.2
Donnan, K.3
Mateo, L.4
Gardner, J.5
Dickinson, J.L.6
Buttigieg, K.7
Suhrbier, A.8
-
54
-
-
0028935381
-
Plasminogen activator inhibitor-2: Prognostic relevance in 1012 patients with primary breast cancer
-
Foekens, J. A., Buessecker, F., Peters, H. A., Krainick, U., van Putten, W. L., Look, M. P., Klijn, J. G. and Kramer, M. D. (1995) Plasminogen activator inhibitor-2: prognostic relevance in 1012 patients with primary breast cancer. Cancer Res. 55, 1423-1427.
-
(1995)
Cancer Res
, vol.55
, pp. 1423-1427
-
-
Foekens, J.A.1
Buessecker, F.2
Peters, H.A.3
Krainick, U.4
van Putten, W.L.5
Look, M.P.6
Klijn, J.G.7
Kramer, M.D.8
-
55
-
-
0031679213
-
Significance of plasminogen activator inhibitor 2 as a prognostic marker in primary lung cancer: Association of decreased plasminogen activator inhibitor 2 with lymph node metastasis
-
Yoshino, H., Endo, Y., Watanabe, Y. and Sasaki, T. (1998) Significance of plasminogen activator inhibitor 2 as a prognostic marker in primary lung cancer: association of decreased plasminogen activator inhibitor 2 with lymph node metastasis. Br. J. Cancer 78, 833-839.
-
(1998)
Br. J. Cancer
, vol.78
, pp. 833-839
-
-
Yoshino, H.1
Endo, Y.2
Watanabe, Y.3
Sasaki, T.4
-
56
-
-
0037311225
-
Plasminogen activator inhibitor-2: A molecular biomarker for head and neck cancer progression
-
Hasina, R., Hulett, K., Bicciato, S., Di Bello, C., Petruzzelli, G. J. and Lingen, M. W. (2003) Plasminogen activator inhibitor-2: a molecular biomarker for head and neck cancer progression. Cancer Res. 63, 555-559.
-
(2003)
Cancer Res
, vol.63
, pp. 555-559
-
-
Hasina, R.1
Hulett, K.2
Bicciato, S.3
Di Bello, C.4
Petruzzelli, G.J.5
Lingen, M.W.6
-
57
-
-
0027263591
-
Type-2 plasminogen-activator inhibitor is a substrate for trophoblast transglutaminase and factor XIIIa. Transglutaminase-catalyzed cross-linking to cellular and extracellular structures
-
Jensen, P. H., Lorand, L., Ebbesen, P. and Gliemann, J. (1993) Type-2 plasminogen-activator inhibitor is a substrate for trophoblast transglutaminase and factor XIIIa. Transglutaminase-catalyzed cross-linking to cellular and extracellular structures. Eur. J. Biochem. 214, 141-146.
-
(1993)
Eur. J. Biochem
, vol.214
, pp. 141-146
-
-
Jensen, P.H.1
Lorand, L.2
Ebbesen, P.3
Gliemann, J.4
-
58
-
-
0028246924
-
Aunique interhelical insertion in plasminogen activator inhibitor-2 contains three glutamines, Gln83, Gln84, Gln86, essential for transglutaminase-mediated cross-linking
-
Jensen, P. H., Schuler, E., Woodrow, G., Richardson, M., Goss, N., Hojrup, P., Petersen, T. E. and Rasmussen, L. K. (1994) Aunique interhelical insertion in plasminogen activator inhibitor-2 contains three glutamines, Gln83, Gln84, Gln86, essential for transglutaminase-mediated cross-linking. J. Biol. Chem. 269, 15394-15398.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 15394-15398
-
-
Jensen, P.H.1
Schuler, E.2
Woodrow, G.3
Richardson, M.4
Goss, N.5
Hojrup, P.6
Petersen, T.E.7
Rasmussen, L.K.8
-
59
-
-
0029861092
-
The exon 3 encoded sequence of the intracellular serine proteinase inhibitor plasminogen activator inhibitor 2 is a protein binding domain
-
Jensen, P. H., Jensen, T. G., Laug, W. E., Hager, H., Gliemann, J. and Pepinsky, B. (1996) The exon 3 encoded sequence of the intracellular serine proteinase inhibitor plasminogen activator inhibitor 2 is a protein binding domain. J. Biol. Chem. 271, 26892-26899.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 26892-26899
-
-
Jensen, P.H.1
Jensen, T.G.2
Laug, W.E.3
Hager, H.4
Gliemann, J.5
Pepinsky, B.6
-
60
-
-
0042691816
-
Inhibition of retinoblastoma protein degradation by interaction with the serpin plasminogen activator inhibitor 2 via a novel consensus motif
-
Darnell, G. A., Antalis, T. M., Johnstone, R. W., Stringer, B. W., Ogbourne, S. M., Harrich, D. and Suhrbier, A. (2003) Inhibition of retinoblastoma protein degradation by interaction with the serpin plasminogen activator inhibitor 2 via a novel consensus motif. Mol. Cell. Biol. 23, 6520-6532.
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 6520-6532
-
-
Darnell, G.A.1
Antalis, T.M.2
Johnstone, R.W.3
Stringer, B.W.4
Ogbourne, S.M.5
Harrich, D.6
Suhrbier, A.7
-
61
-
-
0023932373
-
Mammalian protein secretion without signal peptide removal. Biosynthesis of plasminogen activator inhibitor-2 in U-937 cells
-
Ye, R. D., Wun, T. C. and Sadler, J. E. (1988) Mammalian protein secretion without signal peptide removal. Biosynthesis of plasminogen activator inhibitor-2 in U-937 cells. J. Biol. Chem. 263, 4869-4875.
-
(1988)
J. Biol. Chem
, vol.263
, pp. 4869-4875
-
-
Ye, R.D.1
Wun, T.C.2
Sadler, J.E.3
-
62
-
-
0032145308
-
Secretion of plasminogen activator inhibitor 2 by human peripheral blood monocytes occurs via an endoplasmic reticulum-golgi-independent pathway
-
Ritchie, H. and Booth, N. A. (1998) Secretion of plasminogen activator inhibitor 2 by human peripheral blood monocytes occurs via an endoplasmic reticulum-golgi-independent pathway. Exp. Cell. Res. 242, 439-450.
-
(1998)
Exp. Cell. Res
, vol.242
, pp. 439-450
-
-
Ritchie, H.1
Booth, N.A.2
-
63
-
-
0025868410
-
The efficiency of the uncleaved secretion signal in the plasminogen activator inhibitor type 2 protein can be enhanced by point mutations that increase its hydrophobicity
-
von Heijne, G., Liljestrom, P., Mikus, P., Andersson, H. and Ny, T. (1991) The efficiency of the uncleaved secretion signal in the plasminogen activator inhibitor type 2 protein can be enhanced by point mutations that increase its hydrophobicity. J. Biol. Chem. 266, 15240-15243.
-
(1991)
J. Biol. Chem
, vol.266
, pp. 15240-15243
-
-
von Heijne, G.1
Liljestrom, P.2
Mikus, P.3
Andersson, H.4
Ny, T.5
-
64
-
-
0008558313
-
Ovalbumin: A secreted protein without a transient hydrophobic leader sequence
-
Palmiter, R. D., Gagnon, J. and Walsh, K. A. (1978) Ovalbumin: a secreted protein without a transient hydrophobic leader sequence. Proc. Natl. Acad. Sci. USA 75, 94 -98.
-
(1978)
Proc. Natl. Acad. Sci. USA
, vol.75
, pp. 94-98
-
-
Palmiter, R.D.1
Gagnon, J.2
Walsh, K.A.3
-
65
-
-
33747071796
-
Cytoplasmic and nuclear interaction between Rb family proteins and PAI-2: A physiological crosstalk in human corneal and conjunctival epithelial cells
-
Macaluso, M., Montanari, M., Marshall, C. M., Gambone, A. J., Tosi, G. M., Giordano, A. and Massaro-Giordano, M. (2006) Cytoplasmic and nuclear interaction between Rb family proteins and PAI-2: a physiological crosstalk in human corneal and conjunctival epithelial cells. Cell Death Differ. 13, 1515-1522.
-
(2006)
Cell Death Differ
, vol.13
, pp. 1515-1522
-
-
Macaluso, M.1
Montanari, M.2
Marshall, C.M.3
Gambone, A.J.4
Tosi, G.M.5
Giordano, A.6
Massaro-Giordano, M.7
-
66
-
-
0029875393
-
Intracellular polymerization of the serpin plasminogen activator inhibitor type 2
-
Mikus, P. and Ny, T. (1996) Intracellular polymerization of the serpin plasminogen activator inhibitor type 2. J. Biol. Chem. 271, 10048-10053.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 10048-10053
-
-
Mikus, P.1
Ny, T.2
-
67
-
-
0037446935
-
A redox-sensitive loop regulates plasminogen activator inhibitor type 2 (PAI-2) polymerization
-
Wilczynska, M., Lobov, S., Ohlsson, P. I. and Ny, T. (2003) A redox-sensitive loop regulates plasminogen activator inhibitor type 2 (PAI-2) polymerization. EMBO J. 22, 1753-1761.
-
(2003)
EMBO J
, vol.22
, pp. 1753-1761
-
-
Wilczynska, M.1
Lobov, S.2
Ohlsson, P.I.3
Ny, T.4
-
68
-
-
9344241444
-
Structural bases of the redox-dependent conformational switch in the serpin PAI-2
-
Lobov, S., Wilczynska, M., Bergstrom, F., Johansson, L. B. and Ny, T. (2004) Structural bases of the redox-dependent conformational switch in the serpin PAI-2. J. Mol. Biol. 344, 1359-1368.
-
(2004)
J. Mol. Biol
, vol.344
, pp. 1359-1368
-
-
Lobov, S.1
Wilczynska, M.2
Bergstrom, F.3
Johansson, L.B.4
Ny, T.5
-
69
-
-
0028208912
-
Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells
-
Zou, Z., Anisowicz, A., Hendrix, M. J., Thor, A., Neveu, M., Sheng, S., Rafidi, K., Seftor, E. and Sager, R. (1994) Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells. Science 263, 526-529.
-
(1994)
Science
, vol.263
, pp. 526-529
-
-
Zou, Z.1
Anisowicz, A.2
Hendrix, M.J.3
Thor, A.4
Neveu, M.5
Sheng, S.6
Rafidi, K.7
Seftor, E.8
Sager, R.9
-
70
-
-
33750500906
-
Biological functions of maspin
-
Bailey, C. M., Khalkhali-Ellis, Z., Seftor, E. A. and Hendrix, M. J. (2006) Biological functions of maspin. J. Cell. Physiol. 209, 617-624.
-
(2006)
J. Cell. Physiol
, vol.209
, pp. 617-624
-
-
Bailey, C.M.1
Khalkhali-Ellis, Z.2
Seftor, E.A.3
Hendrix, M.J.4
-
71
-
-
0037071891
-
Maspin sensitizes breast carcinoma cells to induced apoptosis
-
Jiang, N., Meng, Y., Zhang, S., Mensah-Osman, E. and Sheng, S. (2002) Maspin sensitizes breast carcinoma cells to induced apoptosis. Oncogene 21, 4089-4098.
-
(2002)
Oncogene
, vol.21
, pp. 4089-4098
-
-
Jiang, N.1
Meng, Y.2
Zhang, S.3
Mensah-Osman, E.4
Sheng, S.5
-
72
-
-
0033974302
-
Maspin is an angiogenesis inhibitor
-
Zhang, M., Volpert, O., Shi, Y. H. and Bouck, N. (2000) Maspin is an angiogenesis inhibitor. Nat. Med. 6, 196-199.
-
(2000)
Nat. Med
, vol.6
, pp. 196-199
-
-
Zhang, M.1
Volpert, O.2
Shi, Y.H.3
Bouck, N.4
-
73
-
-
0037032993
-
Maspin inhibits cell migration in the absence of protease inhibitory activity
-
Bass, R., Fernandez, A. M. and Ellis, V. (2002) Maspin inhibits cell migration in the absence of protease inhibitory activity. J. Biol. Chem. 277, 46845-46848.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 46845-46848
-
-
Bass, R.1
Fernandez, A.M.2
Ellis, V.3
-
74
-
-
0034096190
-
p53 regulates the expression of the tumor suppressor gene maspin
-
Zou, Z., Gao, C., Nagaich, A. K., Connell, T., Saito, S., Moul, J. W., Seth, P., Appella, E. and Srivastava, S. (2000) p53 regulates the expression of the tumor suppressor gene maspin. J. Biol. Chem. 275, 6051-6054.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 6051-6054
-
-
Zou, Z.1
Gao, C.2
Nagaich, A.K.3
Connell, T.4
Saito, S.5
Moul, J.W.6
Seth, P.7
Appella, E.8
Srivastava, S.9
-
75
-
-
34247274248
-
Nuclear cytokine-activated IKKa controls prostate cancer metastasis by repressing Maspin
-
Luo, J. L., Tan, W., Ricono, J. M., Korchynskyi, O., Zhang, M., Gonias, S. L., Cheresh, D. A. and Karin, M. (2007) Nuclear cytokine-activated IKKa controls prostate cancer metastasis by repressing Maspin. Nature 446, 690-694.
-
(2007)
Nature
, vol.446
, pp. 690-694
-
-
Luo, J.L.1
Tan, W.2
Ricono, J.M.3
Korchynskyi, O.4
Zhang, M.5
Gonias, S.L.6
Cheresh, D.A.7
Karin, M.8
-
76
-
-
0030693825
-
Maspin is an intracellular serpin that partitions into secretory vesicles and is present at the cell surface
-
Pemberton, P. A., Tipton, A. R., Pavloff, N., Smith, J., Erickson, J. R., Mouchabeck, Z. M. and Kiefer, M. C. (1997) Maspin is an intracellular serpin that partitions into secretory vesicles and is present at the cell surface. J. Histochem. Cytochem. 45, 1697-1706.
-
(1997)
J. Histochem. Cytochem
, vol.45
, pp. 1697-1706
-
-
Pemberton, P.A.1
Tipton, A.R.2
Pavloff, N.3
Smith, J.4
Erickson, J.R.5
Mouchabeck, Z.M.6
Kiefer, M.C.7
-
77
-
-
0036715316
-
The paradoxical expression of maspin in ovarian carcinoma
-
Sood, A. K., Fletcher, M. S., Gruman, L. M., Coffin, J. E., Jabbari, S., Khalkhali-Ellis, Z., Arbour, N., Seftor, E. A. and Hendrix, M. J. (2002)The paradoxical expression of maspin in ovarian carcinoma. Clin. Cancer Res. 8, 2924-2932.
-
(2002)
Clin. Cancer Res
, vol.8
, pp. 2924-2932
-
-
Sood, A.K.1
Fletcher, M.S.2
Gruman, L.M.3
Coffin, J.E.4
Jabbari, S.5
Khalkhali-Ellis, Z.6
Arbour, N.7
Seftor, E.A.8
Hendrix, M.J.9
-
78
-
-
30644466498
-
Maspin nuclear localization is linked to favorable morphological features in pulmonary adenocarcinoma
-
Lonardo, F., Li, X., Siddiq, F., Singh, R., Al-Abbadi, M., Pass, H. I. and Sheng, S. (2006) Maspin nuclear localization is linked to favorable morphological features in pulmonary adenocarcinoma. Lung Cancer 51, 31 -39.
-
(2006)
Lung Cancer
, vol.51
, pp. 31-39
-
-
Lonardo, F.1
Li, X.2
Siddiq, F.3
Singh, R.4
Al-Abbadi, M.5
Pass, H.I.6
Sheng, S.7
-
79
-
-
14044269508
-
Maspin mediates increased tumor cell apoptosis upon induction of the mitochondrial permeability transition
-
Latha, K., Zhang, W., Cella, N., Shi, H. Y. and Zhang, M. (2005) Maspin mediates increased tumor cell apoptosis upon induction of the mitochondrial permeability transition. Mol. Cell. Biol. 25, 1737-1748.
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 1737-1748
-
-
Latha, K.1
Zhang, W.2
Cella, N.3
Shi, H.Y.4
Zhang, M.5
-
80
-
-
33845608469
-
Maspin is physically associated with β1 integrin regulating cell adhesion in mammary epithelial cells
-
Cella, N., Contreras, A., Latha, K., Rosen, J. M. and Zhang, M. (2006) Maspin is physically associated with β1 integrin regulating cell adhesion in mammary epithelial cells. FASEB J. 20, 1510-1512.
-
(2006)
FASEB J
, vol.20
, pp. 1510-1512
-
-
Cella, N.1
Contreras, A.2
Latha, K.3
Rosen, J.M.4
Zhang, M.5
-
81
-
-
0037192782
-
Evidence for a direct interaction between the tumor suppressor serpin, maspin, and types I and III collagen
-
Blacque, O. E. and Worrall, D. M. (2002) Evidence for a direct interaction between the tumor suppressor serpin, maspin, and types I and III collagen. J. Biol. Chem. 277, 10783-10788.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 10783-10788
-
-
Blacque, O.E.1
Worrall, D.M.2
-
82
-
-
0041856173
-
Sufficiency of the reactive site loop of maspin for induction of cell-matrix adhesion and inhibition of cell invasion. Conversion of ovalbumin to a maspin-like molecule
-
Ngamkitidechakul, C., Warejcka, D. J., Burke, J. M., O'Brien, W. J. and Twining, S. S. (2003) Sufficiency of the reactive site loop of maspin for induction of cell-matrix adhesion and inhibition of cell invasion. Conversion of ovalbumin to a maspin-like molecule. J. Biol. Chem. 278, 31796-31806.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 31796-31806
-
-
Ngamkitidechakul, C.1
Warejcka, D.J.2
Burke, J.M.3
O'Brien, W.J.4
Twining, S.S.5
-
83
-
-
0032535006
-
maspin suppresses the invasive phenotype of human breast carcinoma
-
Seftor, R. E., Seftor, E. A., Sheng, S., Pemberton, P. A., Sager, R. and Hendrix, M. J. (1998) maspin suppresses the invasive phenotype of human breast carcinoma. Cancer Res. 58, 5681-5685.
-
(1998)
Cancer Res
, vol.58
, pp. 5681-5685
-
-
Seftor, R.E.1
Seftor, E.A.2
Sheng, S.3
Pemberton, P.A.4
Sager, R.5
Hendrix, M.J.6
-
84
-
-
0035893565
-
Pleiotrophic inhibition of pericellular urokinase-type plasminogen activator system by endogenous tumor suppressive maspin
-
Biliran, H., Jr. and Sheng, S. (2001) Pleiotrophic inhibition of pericellular urokinase-type plasminogen activator system by endogenous tumor suppressive maspin. Cancer Res. 61, 8676-8682.
-
(2001)
Cancer Res
, vol.61
, pp. 8676-8682
-
-
Biliran Jr., H.1
Sheng, S.2
-
85
-
-
33646271356
-
Maspin retards cell detachment via a novel interaction with the urokinase-type plasminogen activator/urokinase-type plasminogen activator receptor system
-
Yin, S., Lockett, J., Meng, Y., Biliran, H., Jr., Blouse, G. E., Li, X., Reddy, N., Zhao, Z., Lin, X., Anagli, J., Cher, M. L. and Sheng, S. (2006) Maspin retards cell detachment via a novel interaction with the urokinase-type plasminogen activator/urokinase-type plasminogen activator receptor system. Cancer Res. 66, 4173-4181.
-
(2006)
Cancer Res
, vol.66
, pp. 4173-4181
-
-
Yin, S.1
Lockett, J.2
Meng, Y.3
Biliran Jr., H.4
Blouse, G.E.5
Li, X.6
Reddy, N.7
Zhao, Z.8
Lin, X.9
Anagli, J.10
Cher, M.L.11
Sheng, S.12
-
86
-
-
33750517528
-
A role of novel serpin maspin in tumor progression: The divergence revealed through efforts to converge
-
Sheng, S. (2006) A role of novel serpin maspin in tumor progression: the divergence revealed through efforts to converge. J. Cell. Physiol. 209, 631-635.
-
(2006)
J. Cell. Physiol
, vol.209
, pp. 631-635
-
-
Sheng, S.1
-
87
-
-
34547104854
-
Maspin binds to urokinase-type and tissue-type plasminogen activator through exosite-exosite interactions
-
Al-Ayyoubi, M., Schwartz, B. S. and Gettins, P. G. (2007) Maspin binds to urokinase-type and tissue-type plasminogen activator through exosite-exosite interactions. J. Biol. Chem. 282, 19502-19509.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 19502-19509
-
-
Al-Ayyoubi, M.1
Schwartz, B.S.2
Gettins, P.G.3
-
88
-
-
26944447657
-
Tumor-suppressive maspin regulates cell response to oxidative stress by direct interaction with glutathione S-transferase
-
Yin, S., Li, X., Meng, Y., Finley, R. L., Jr., Sakr, W., Yang, H., Reddy, N. and Sheng, S. (2005) Tumor-suppressive maspin regulates cell response to oxidative stress by direct interaction with glutathione S-transferase. J. Biol. Chem. 280, 34985-34996.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 34985-34996
-
-
Yin, S.1
Li, X.2
Meng, Y.3
Finley Jr., R.L.4
Sakr, W.5
Yang, H.6
Reddy, N.7
Sheng, S.8
-
89
-
-
26644456963
-
Mammary serine protease inhibitor (Maspin) binds directly to interferon regulatory factor 6: Identification of a novel serpin partnership
-
Bailey, C. M., Khalkhali-Ellis, Z., Kondo, S., Margaryan, N. V., Seftor, R. E., Wheaton, W. W., Amir, S., Pins, M. R., Schutte, B. C. and Hendrix, M. J. (2005) Mammary serine protease inhibitor (Maspin) binds directly to interferon regulatory factor 6: identification of a novel serpin partnership. J. Biol. Chem. 280, 34210-34217.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 34210-34217
-
-
Bailey, C.M.1
Khalkhali-Ellis, Z.2
Kondo, S.3
Margaryan, N.V.4
Seftor, R.E.5
Wheaton, W.W.6
Amir, S.7
Pins, M.R.8
Schutte, B.C.9
Hendrix, M.J.10
-
90
-
-
33749489404
-
Endogenous inhibition of histone deacetylase 1 by tumor-suppressive maspin
-
Li, X., Yin, S., Meng, Y., Sakr, W. and Sheng, S. (2006) Endogenous inhibition of histone deacetylase 1 by tumor-suppressive maspin. Cancer Res. 66, 9323-9329.
-
(2006)
Cancer Res
, vol.66
, pp. 9323-9329
-
-
Li, X.1
Yin, S.2
Meng, Y.3
Sakr, W.4
Sheng, S.5
-
91
-
-
0017762441
-
Radioimmunoassay for tumor antigen of human cervical squamous cell carcinoma
-
Kato, H. and Torigoe, T. (1977) Radioimmunoassay for tumor antigen of human cervical squamous cell carcinoma. Cancer 40, 1621-1628.
-
(1977)
Cancer
, vol.40
, pp. 1621-1628
-
-
Kato, H.1
Torigoe, T.2
-
92
-
-
0026326039
-
Squamous cell carcinoma antigen is a new member of the serine protease inhibitors
-
Suminami, Y., Kishi, F., Sekiguchi, K. and Kato, H. (1991) Squamous cell carcinoma antigen is a new member of the serine protease inhibitors. Biochem. Biophys. Res. Commun. 181, 51-58.
-
(1991)
Biochem. Biophys. Res. Commun
, vol.181
, pp. 51-58
-
-
Suminami, Y.1
Kishi, F.2
Sekiguchi, K.3
Kato, H.4
-
93
-
-
0028943628
-
A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene
-
Schneider, S. S., Schick, C., Fish, K. E., Miller, E., Pena, J. C., Treter, S. D., Hui, S. M. and Silverman, G. A. (1995) A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene. Proc. Natl. Acad. Sci. USA 92, 3147-3151.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 3147-3151
-
-
Schneider, S.S.1
Schick, C.2
Fish, K.E.3
Miller, E.4
Pena, J.C.5
Treter, S.D.6
Hui, S.M.7
Silverman, G.A.8
-
94
-
-
0031032401
-
Squamous cell carcinoma antigen 2 is a novel serpin that inhibits the chymotrypsin-like proteinases cathepsin G and mast cell chymase
-
Schick, C., Kamachi, Y., Bartuski, A. J., Cataltepe, S., Schechter, N. M., Pemberton, P. A. and Silverman, G. A. (1997) Squamous cell carcinoma antigen 2 is a novel serpin that inhibits the chymotrypsin-like proteinases cathepsin G and mast cell chymase. J. Biol. Chem. 272, 1849-1855.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 1849-1855
-
-
Schick, C.1
Kamachi, Y.2
Bartuski, A.J.3
Cataltepe, S.4
Schechter, N.M.5
Pemberton, P.A.6
Silverman, G.A.7
-
95
-
-
0034691279
-
Simple modifications of the serpin reactive site loop convert SCCA2 into a cysteine proteinase inhibitor: A critical role for the P3′ proline in facilitating RSL cleavage
-
Luke, C., Schick, C., Tsu, C., Whisstock, J. C., Irving, J. A., Bromme, D., Juliano, L., Shi, G. P., Chapman, H. A. and Silverman, G. A. (2000) Simple modifications of the serpin reactive site loop convert SCCA2 into a cysteine proteinase inhibitor: a critical role for the P3′ proline in facilitating RSL cleavage. Biochemistry 39, 7081-7091.
-
(2000)
Biochemistry
, vol.39
, pp. 7081-7091
-
-
Luke, C.1
Schick, C.2
Tsu, C.3
Whisstock, J.C.4
Irving, J.A.5
Bromme, D.6
Juliano, L.7
Shi, G.P.8
Chapman, H.A.9
Silverman, G.A.10
-
96
-
-
0033977583
-
Co-expression of the squamous cell carcinoma antigens 1 and 2 in normal adult human tissues and squamous cell carcinomas
-
Cataltepe, S., Gornstein, E. R., Schick, C., Kamachi, Y., Chatson, K., Fries, J., Silverman, G. A. and Upton, M. P. (2000) Co-expression of the squamous cell carcinoma antigens 1 and 2 in normal adult human tissues and squamous cell carcinomas. J. Histochem. Cytochem. 48, 113-122.
-
(2000)
J. Histochem. Cytochem
, vol.48
, pp. 113-122
-
-
Cataltepe, S.1
Gornstein, E.R.2
Schick, C.3
Kamachi, Y.4
Chatson, K.5
Fries, J.6
Silverman, G.A.7
Upton, M.P.8
-
97
-
-
0002825780
-
-
S. Sell, ed, pp, Humana Press, Totowa, NJ
-
Kato H. (1992) Squamous cell carcinoma antigen In: Serological Cancer Markers (S. Sell, ed.) pp. 437-451, Humana Press, Totowa, NJ
-
(1992)
Squamous cell carcinoma antigen In: Serological Cancer Markers
, pp. 437-451
-
-
Kato, H.1
-
98
-
-
0034691545
-
Circulating serpin tumor markers SCCA1 and SCCA2 are not actively secreted but reside in the cytosol of squamous carcinoma cells
-
Uemura, Y., Pak, S. C., Luke, C., Cataltepe, S., Tsu, C., Schick, C., Kamachi, Y., Pomeroy, S. L., Perlmutter, D. H. and Silverman, G. A. (2000) Circulating serpin tumor markers SCCA1 and SCCA2 are not actively secreted but reside in the cytosol of squamous carcinoma cells. Int. J. Cancer 89, 368-377.
-
(2000)
Int. J. Cancer
, vol.89
, pp. 368-377
-
-
Uemura, Y.1
Pak, S.C.2
Luke, C.3
Cataltepe, S.4
Tsu, C.5
Schick, C.6
Kamachi, Y.7
Pomeroy, S.L.8
Perlmutter, D.H.9
Silverman, G.A.10
-
99
-
-
50249187220
-
-
in press, Med. Chem
-
Izuhara, K., Kanaji, S., Arima, K., Ohta, S. and Shiraishi, H. (in press) Involvement of cysteine protease inhibitors in the defense mechanism against parasites. Med. Chem.
-
Involvement of cysteine protease inhibitors in the defense mechanism against parasites
-
-
Izuhara, K.1
Kanaji, S.2
Arima, K.3
Ohta, S.4
Shiraishi, H.5
-
100
-
-
18744388830
-
Analysis of novel disease-related genes in bronchial asthma
-
Yuyama, N., Davies, D. E., Akaiwa, M., Matsui, K., Hamasaki, Y., Suminami, Y., Yoshida, N. L., Maeda, M., Pandit, A., Lordan, J. L., Kamogawa, Y., Arima, K., Nagumo, F., Sugimachi, M., Berger, A., Richards, I., Roberds, S. L., Yamashita, T., Kishi, F., Kato, H., Arai, K., Ohshima, K., Tadano, J., Hamasaki, N., Miyatake, S., Sugita, Y., Holgate, S. T. and Izuhara, K. (2002) Analysis of novel disease-related genes in bronchial asthma. Cytokine 19, 287-296.
-
(2002)
Cytokine
, vol.19
, pp. 287-296
-
-
Yuyama, N.1
Davies, D.E.2
Akaiwa, M.3
Matsui, K.4
Hamasaki, Y.5
Suminami, Y.6
Yoshida, N.L.7
Maeda, M.8
Pandit, A.9
Lordan, J.L.10
Kamogawa, Y.11
Arima, K.12
Nagumo, F.13
Sugimachi, M.14
Berger, A.15
Richards, I.16
Roberds, S.L.17
Yamashita, T.18
Kishi, F.19
Kato, H.20
Arai, K.21
Ohshima, K.22
Tadano, J.23
Hamasaki, N.24
Miyatake, S.25
Sugita, Y.26
Holgate, S.T.27
Izuhara, K.28
more..
-
101
-
-
33644837166
-
The squamous cell carcinoma antigens as relevant biomarkers of atopic dermatitis
-
Mitsuishi, K., Nakamura, T., Sakata, Y., Yuyama, N., Arima, K., Sugita, Y., Suto, H., Izuhara, K. and Ogawa, H. (2005) The squamous cell carcinoma antigens as relevant biomarkers of atopic dermatitis. Clin. Exp. Allergy 35, 1327-1333.
-
(2005)
Clin. Exp. Allergy
, vol.35
, pp. 1327-1333
-
-
Mitsuishi, K.1
Nakamura, T.2
Sakata, Y.3
Yuyama, N.4
Arima, K.5
Sugita, Y.6
Suto, H.7
Izuhara, K.8
Ogawa, H.9
-
102
-
-
33645293443
-
Serpin squamous cell carcinoma antigen inhibits UV-induced apoptosis via suppression of c-JUN NH2-terminal kinase
-
Katagiri, C., Nakanishi, J., Kadoya, K. and Hibino, T. (2006) Serpin squamous cell carcinoma antigen inhibits UV-induced apoptosis via suppression of c-JUN NH2-terminal kinase. J. Cell. Biol. 172, 983-990.
-
(2006)
J. Cell. Biol
, vol.172
, pp. 983-990
-
-
Katagiri, C.1
Nakanishi, J.2
Kadoya, K.3
Hibino, T.4
-
103
-
-
37549070361
-
DNA accelerates the inhibition of human cathepsin v by serpins
-
Ong, P. C., McGowan, S., Pearce, M. C., Irving, J. A., Kan, W. T., Grigoryev, S. A., Turk, B., Silverman, G. A., Brix, K., Bottomley, S. P., Whisstock, J. C. and Pike, R. N. (2007) DNA accelerates the inhibition of human cathepsin v by serpins. J. Biol. Chem. 282, 36980-36986.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 36980-36986
-
-
Ong, P.C.1
McGowan, S.2
Pearce, M.C.3
Irving, J.A.4
Kan, W.T.5
Grigoryev, S.A.6
Turk, B.7
Silverman, G.A.8
Brix, K.9
Bottomley, S.P.10
Whisstock, J.C.11
Pike, R.N.12
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