Procyanidins from wild grape (Vitis amurensis) seeds regulate ARE-mediated enzyme expression via Nrf2 coupled with p38 and PI3K/Akt pathway in HepG2 cells

International Journal of Molecular Sciences

Volumn 13, Issue 1, 2012, Pages 801-818

  Bak, Min Ji ^a   Jun, Mira ^b   Jeong, Woo Sik ^a  

^a Inje University   (South Korea)

^b Dong A University   (South Korea)

Author keywords

Antioxidant enzyme; Chemoprevention; MAPKs; Nrf2; Phase ii detoxifying enzyme; Procyanidin; Vitis amurensis; Wild grape seed

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALCOHOL; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BUTANOL; HEME OXYGENASE 1; MITOGEN ACTIVATED PROTEIN KINASE; ORGANIC SOLVENT; PHLOROGLUCINOL; PHOSPHATIDYLINOSITOL 3 KINASE; PROCYANIDIN DERIVATIVE; PROTEIN KINASE B; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SYNAPTOPHYSIN; TRANSCRIPTION FACTOR NRF2; VANILLIN; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; BIFLAVONOID; CATECHIN; CHROMONE DERIVATIVE; FLAVAN-3-OL; FLAVONOID; MITOGEN ACTIVATED PROTEIN KINASE P38; MORPHOLINE DERIVATIVE; NQO1 PROTEIN, HUMAN; PROANTHOCYANIDIN; PROCYANIDIN;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CANCER INHIBITION; CELL STRAIN HEPG2; CONTROLLED STUDY; DEPOLYMERIZATION; DRUG DETERMINATION; FRACTIONATION; GRAPE; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; LIVER CELL CARCINOMA; MASS SPECTROMETRY; PLANT SEED; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION; SIGNAL TRANSDUCTION; WILD TYPE; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG EFFECTS; GENE EXPRESSION; HEPG2 CELL LINE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION AND PURIFICATION; METABOLISM; VITIS;

VITACEAE; VITIS AMURENSIS;

BIFLAVONOIDS; CATECHIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMONES; FLAVONOIDS; GENE EXPRESSION; HEME OXYGENASE-1; HEP G2 CELLS; HUMANS; MASS SPECTROMETRY; MORPHOLINES; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLINOSITOL 3-KINASES; PROANTHOCYANIDINS; PROTO-ONCOGENE PROTEINS C-AKT; SEEDS; SIGNAL TRANSDUCTION; VITIS;

EID: 84856285890     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms13010801     Document Type: Article

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