메뉴 건너뛰기




Volumn 135, Issue 3, 2012, Pages 198-206

Dissecting T-cell activation with high-resolution live-cell microscopy

Author keywords

Immune synapse; Photoactivated localization microscopy; Stochastic optical reconstruction microscopy; Super resolution; TOCCSL; Two colour coincidence detection

Indexed keywords

LIPID; T LYMPHOCYTE RECEPTOR;

EID: 84856207761     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2011.03537.x     Document Type: Review
Times cited : (5)

References (64)
  • 1
    • 0028179006 scopus 로고
    • Lymphocyte responses and cytokines
    • Paul WE, Seder RA. Lymphocyte responses and cytokines. Cell 1994; 76:241-51.
    • (1994) Cell , vol.76 , pp. 241-251
    • Paul, W.E.1    Seder, R.A.2
  • 3
    • 0032480279 scopus 로고    scopus 로고
    • Three-dimensional segregation of supramolecular activation clusters in T cells
    • Monks CR, Freiberg BA, Kupfer H, Sciaky N, Kupfer A. Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 1998; 395:82-6.
    • (1998) Nature , vol.395 , pp. 82-86
    • Monks, C.R.1    Freiberg, B.A.2    Kupfer, H.3    Sciaky, N.4    Kupfer, A.5
  • 4
    • 27544441784 scopus 로고    scopus 로고
    • Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling
    • Campi G, Varma R, Dustin ML. Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling. J Exp Med 2005; 202:1031-6.
    • (2005) J Exp Med , vol.202 , pp. 1031-1036
    • Campi, G.1    Varma, R.2    Dustin, M.L.3
  • 5
    • 77249114784 scopus 로고    scopus 로고
    • TCR-peptide-MHC interactions in situ show accelerated kinetics and increased affinity
    • Huppa JB, Axmann M, Mortelmaier MA et al. TCR-peptide-MHC interactions in situ show accelerated kinetics and increased affinity. Nature 2010; 463:963-7.
    • (2010) Nature , vol.463 , pp. 963-967
    • Huppa, J.B.1    Axmann, M.2    Mortelmaier, M.A.3
  • 6
    • 69249202271 scopus 로고    scopus 로고
    • Supported bilayers at the vanguard of immune cell activation studies
    • Dustin ML. Supported bilayers at the vanguard of immune cell activation studies. J Struct Biol 2009; 168:152-60.
    • (2009) J Struct Biol , vol.168 , pp. 152-160
    • Dustin, M.L.1
  • 7
    • 36749064485 scopus 로고    scopus 로고
    • Single-molecule level analysis of the subunit composition of the T cell receptor on live T cells
    • James JR, White SS, Clarke RW et al. Single-molecule level analysis of the subunit composition of the T cell receptor on live T cells. Proc Natl Acad Sci U S A 2007; 104:17662-7.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 17662-17667
    • James, J.R.1    White, S.S.2    Clarke, R.W.3
  • 11
    • 77950908560 scopus 로고    scopus 로고
    • Insights into function of the immunological synapse from studies with supported planar bilayers
    • Dustin ML. Insights into function of the immunological synapse from studies with supported planar bilayers. Curr Top Microbiol Immunol 2010; 340:1-24.
    • (2010) Curr Top Microbiol Immunol , vol.340 , pp. 1-24
    • Dustin, M.L.1
  • 12
    • 38049136514 scopus 로고    scopus 로고
    • Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells
    • Kaizuka Y, Douglass AD, Varma R, Dustin ML, Vale RD. Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells. Proc Natl Acad Sci U S A 2007; 104:20296-301.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 20296-20301
    • Kaizuka, Y.1    Douglass, A.D.2    Varma, R.3    Dustin, M.L.4    Vale, R.D.5
  • 13
    • 65649098764 scopus 로고    scopus 로고
    • The coreceptor CD2 uses plasma membrane microdomains to transduce signals in T cells
    • Kaizuka Y, Douglass AD, Vardhana S, Dustin ML, Vale RD. The coreceptor CD2 uses plasma membrane microdomains to transduce signals in T cells. J Cell Biol 2009; 185:521-34.
    • (2009) J Cell Biol , vol.185 , pp. 521-534
    • Kaizuka, Y.1    Douglass, A.D.2    Vardhana, S.3    Dustin, M.L.4    Vale, R.D.5
  • 14
    • 43149088046 scopus 로고    scopus 로고
    • T cell receptor microcluster transport through molecular mazes reveals mechanism of translocation
    • DeMond AL, Mossman KD, Starr T, Dustin ML, Groves JT. T cell receptor microcluster transport through molecular mazes reveals mechanism of translocation. Biophys J 2008; 94:3286-92.
    • (2008) Biophys J , vol.94 , pp. 3286-3292
    • DeMond, A.L.1    Mossman, K.D.2    Starr, T.3    Dustin, M.L.4    Groves, J.T.5
  • 15
    • 77955623486 scopus 로고    scopus 로고
    • Altered actin centripetal retrograde flow in physically restricted immunological synapses
    • e11878
    • Yu CH, Wu HJ, Kaizuka Y, Vale RD, Groves JT. Altered actin centripetal retrograde flow in physically restricted immunological synapses. PLoS ONE 2010; 5:e11878.
    • (2010) PLoS ONE , vol.5
    • Yu, C.H.1    Wu, H.J.2    Kaizuka, Y.3    Vale, R.D.4    Groves, J.T.5
  • 16
    • 27944442353 scopus 로고    scopus 로고
    • Altered TCR signaling from geometrically repatterned immunological synapses
    • Mossman KD, Campi G, Groves JT, Dustin ML. Altered TCR signaling from geometrically repatterned immunological synapses. Science 2005; 310:1191-3.
    • (2005) Science , vol.310 , pp. 1191-1193
    • Mossman, K.D.1    Campi, G.2    Groves, J.T.3    Dustin, M.L.4
  • 17
    • 69149100929 scopus 로고    scopus 로고
    • Cluster size regulates protein sorting in the immunological synapse
    • Hartman NC, Nye JA, Groves JT. Cluster size regulates protein sorting in the immunological synapse. Proc Natl Acad Sci U S A 2009; 106:12729-34.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 12729-12734
    • Hartman, N.C.1    Nye, J.A.2    Groves, J.T.3
  • 18
    • 33745752076 scopus 로고    scopus 로고
    • Curvature-modulated phase separation in lipid bilayer membranes
    • Parthasarathy R, Yu CH, Groves JT. Curvature-modulated phase separation in lipid bilayer membranes. Langmuir 2006; 22:5095-9.
    • (2006) Langmuir , vol.22 , pp. 5095-5099
    • Parthasarathy, R.1    Yu, C.H.2    Groves, J.T.3
  • 19
    • 28444476999 scopus 로고    scopus 로고
    • Membrane curvature and mechanisms of dynamic cell membrane remodelling
    • McMahon HT, Gallop JL. Membrane curvature and mechanisms of dynamic cell membrane remodelling. Nature 2005; 438:590-6.
    • (2005) Nature , vol.438 , pp. 590-596
    • McMahon, H.T.1    Gallop, J.L.2
  • 20
    • 66249127141 scopus 로고    scopus 로고
    • Sorting of lipids and proteins in membrane curvature gradients
    • Tian A, Baumgart T. Sorting of lipids and proteins in membrane curvature gradients. Biophys J 2009; 96:2676-88.
    • (2009) Biophys J , vol.96 , pp. 2676-2688
    • Tian, A.1    Baumgart, T.2
  • 21
    • 33746114879 scopus 로고    scopus 로고
    • The kinetic-segregation model: TCR triggering and beyond
    • Davis SJ, van der Merwe PA. The kinetic-segregation model: TCR triggering and beyond. Nat Immunol 2006; 7:803-9.
    • (2006) Nat Immunol , vol.7 , pp. 803-809
    • Davis, S.J.1    van der Merwe, P.A.2
  • 22
    • 0034005120 scopus 로고    scopus 로고
    • Cytoskeletal polarization and redistribution of cell surface molecules during T cell antigen recognition
    • van der Merwe PA, Davis SJ, Shaw AS, Dustin ML. Cytoskeletal polarization and redistribution of cell surface molecules during T cell antigen recognition. Semin Immunol 2000; 12:5-21.
    • (2000) Semin Immunol , vol.12 , pp. 5-21
    • van der Merwe, P.A.1    Davis, S.J.2    Shaw, A.S.3    Dustin, M.L.4
  • 23
    • 0345466367 scopus 로고    scopus 로고
    • Free Brownian motion of individual lipid molecules in biomembranes
    • Sonnleitner A, Schutz GJ, Schmidt T. Free Brownian motion of individual lipid molecules in biomembranes. Biophys J 1999; 77:2638-42.
    • (1999) Biophys J , vol.77 , pp. 2638-2642
    • Sonnleitner, A.1    Schutz, G.J.2    Schmidt, T.3
  • 24
    • 0032477992 scopus 로고    scopus 로고
    • Asymmetric molecular friction in supported phospholipid bilayers revealed by NMR measurements of lipid diffusion
    • Hetzer M, Heinz S, Grage S, Bayerl TM. Asymmetric molecular friction in supported phospholipid bilayers revealed by NMR measurements of lipid diffusion. Langmuir 1998; 14:982-4.
    • (1998) Langmuir , vol.14 , pp. 982-984
    • Hetzer, M.1    Heinz, S.2    Grage, S.3    Bayerl, T.M.4
  • 28
    • 20444404267 scopus 로고    scopus 로고
    • Single-molecule microscopy reveals plasma membrane microdomains created by protein-protein networks that exclude or trap signaling molecules in T cells
    • Douglass AD, Vale RD. Single-molecule microscopy reveals plasma membrane microdomains created by protein-protein networks that exclude or trap signaling molecules in T cells. Cell 2005; 121:937-50.
    • (2005) Cell , vol.121 , pp. 937-950
    • Douglass, A.D.1    Vale, R.D.2
  • 29
    • 34447508103 scopus 로고    scopus 로고
    • Single-molecule microscopy reveals heterogeneous dynamics of lipid raft components upon TCR engagement
    • Drbal K, Moertelmaier M, Holzhauser C et al. Single-molecule microscopy reveals heterogeneous dynamics of lipid raft components upon TCR engagement. Int Immunol 2007; 19:675-84.
    • (2007) Int Immunol , vol.19 , pp. 675-684
    • Drbal, K.1    Moertelmaier, M.2    Holzhauser, C.3
  • 31
    • 78650637436 scopus 로고    scopus 로고
    • Imaging of mobile long-lived nanoplatforms in the live cell plasma membrane
    • Brameshuber M, Weghuber J, Ruprecht V et al. Imaging of mobile long-lived nanoplatforms in the live cell plasma membrane. J Biol Chem 2010; 285:41765-71.
    • (2010) J Biol Chem , vol.285 , pp. 41765-41771
    • Brameshuber, M.1    Weghuber, J.2    Ruprecht, V.3
  • 32
    • 77954380512 scopus 로고    scopus 로고
    • TCR-microclusters critical for T-cell activation are formed independently of lipid raft clustering
    • Hashimoto-Tane A, Yokosuka T, Ishihara C, Sakuma M, Kobayashi W, Saito T. TCR-microclusters critical for T-cell activation are formed independently of lipid raft clustering. Mol Cell Biol 2010; 30:3421-9.
    • (2010) Mol Cell Biol , vol.30 , pp. 3421-3429
    • Hashimoto-Tane, A.1    Yokosuka, T.2    Ishihara, C.3    Sakuma, M.4    Kobayashi, W.5    Saito, T.6
  • 33
    • 44649160533 scopus 로고    scopus 로고
    • Have we become overly reliant on lipid rafts? Talking Point on the involvement of lipid rafts in T-cell activation
    • Kenworthy AK. Have we become overly reliant on lipid rafts? Talking Point on the involvement of lipid rafts in T-cell activation. EMBO Rep 2008; 9:531-5.
    • (2008) EMBO Rep , vol.9 , pp. 531-535
    • Kenworthy, A.K.1
  • 34
    • 62049084949 scopus 로고    scopus 로고
    • Accumulation of raft lipids in T-cell plasma membrane domains engaged in TCR signalling
    • Zech T, Ejsing CS, Gaus K, de Wet B, Shevchenko A, Simons K, Harder T. Accumulation of raft lipids in T-cell plasma membrane domains engaged in TCR signalling. EMBO J 2009; 28:466-76.
    • (2009) EMBO J , vol.28 , pp. 466-476
    • Zech, T.1    Ejsing, C.S.2    Gaus, K.3    de Wet, B.4    Shevchenko, A.5    Simons, K.6    Harder, T.7
  • 35
    • 77949900052 scopus 로고    scopus 로고
    • Direct observation and quantitative analysis of Lck exchange between plasma membrane and cytosol in living T cells
    • Zimmermann L, Paster W, Weghuber J, Eckerstorfer P, Stockinger H, Schutz GJ. Direct observation and quantitative analysis of Lck exchange between plasma membrane and cytosol in living T cells. J Biol Chem 2010; 285:6063-70.
    • (2010) J Biol Chem , vol.285 , pp. 6063-6070
    • Zimmermann, L.1    Paster, W.2    Weghuber, J.3    Eckerstorfer, P.4    Stockinger, H.5    Schutz, G.J.6
  • 36
    • 33747179417 scopus 로고    scopus 로고
    • Imaging intracellular fluorescent proteins at nanometer resolution
    • Betzig E, Patterson GH, Sougrat R et al. Imaging intracellular fluorescent proteins at nanometer resolution. Science 2006; 313:1642-5.
    • (2006) Science , vol.313 , pp. 1642-1645
    • Betzig, E.1    Patterson, G.H.2    Sougrat, R.3
  • 37
    • 33749026335 scopus 로고    scopus 로고
    • Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM)
    • Rust MJ, Bates M, Zhuang X. Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM). Nat Methods 2006; 3:793-5.
    • (2006) Nat Methods , vol.3 , pp. 793-795
    • Rust, M.J.1    Bates, M.2    Zhuang, X.3
  • 38
    • 24944484744 scopus 로고    scopus 로고
    • Superresolution by localization of quantum dots using blinking statistics
    • Lidke K, Rieger B, Jovin T, Heintzmann R. Superresolution by localization of quantum dots using blinking statistics. Opt Express 2005; 13:7052-62.
    • (2005) Opt Express , vol.13 , pp. 7052-7062
    • Lidke, K.1    Rieger, B.2    Jovin, T.3    Heintzmann, R.4
  • 42
    • 34648826792 scopus 로고    scopus 로고
    • Multicolor super-resolution imaging with photo-switchable fluorescent probes
    • Bates M, Huang B, Dempsey GT, Zhuang X. Multicolor super-resolution imaging with photo-switchable fluorescent probes. Science 2007; 317:1749-53.
    • (2007) Science , vol.317 , pp. 1749-1753
    • Bates, M.1    Huang, B.2    Dempsey, G.T.3    Zhuang, X.4
  • 43
    • 42949083695 scopus 로고    scopus 로고
    • Live-cell photoactivated localization microscopy of nanoscale adhesion dynamics
    • Shroff H, Galbraith CG, Galbraith JA, Betzig E. Live-cell photoactivated localization microscopy of nanoscale adhesion dynamics. Nat Methods 2008; 5:417-23.
    • (2008) Nat Methods , vol.5 , pp. 417-423
    • Shroff, H.1    Galbraith, C.G.2    Galbraith, J.A.3    Betzig, E.4
  • 45
    • 58749115780 scopus 로고    scopus 로고
    • Photoactivated localization microscopy (PALM) of adhesion complexes
    • Supplement 41, Unit 4.21
    • Shroff H, White H, Betzig E. Photoactivated localization microscopy (PALM) of adhesion complexes. Curr Protoc Cell Biol 2008; Supplement 41, Unit 4.21, 1-27.
    • (2008) Curr Protoc Cell Biol , pp. 1-27
    • Shroff, H.1    White, H.2    Betzig, E.3
  • 46
    • 33646137152 scopus 로고    scopus 로고
    • Immunological synapse and microclusters: the site for recognition and activation of T cells
    • Saito T, Yokosuka T. Immunological synapse and microclusters: the site for recognition and activation of T cells. Curr Opin Immunol 2006; 18:305-13.
    • (2006) Curr Opin Immunol , vol.18 , pp. 305-313
    • Saito, T.1    Yokosuka, T.2
  • 48
  • 50
    • 33751204491 scopus 로고    scopus 로고
    • Determination of the fraction and stoichiometry of femtomolar levels of biomolecular complexes in an excess of monomer using single-molecule, two-color coincidence detection
    • Orte A, Clarke R, Balasubramanian S, Klenerman D. Determination of the fraction and stoichiometry of femtomolar levels of biomolecular complexes in an excess of monomer using single-molecule, two-color coincidence detection. Anal Chem 2006; 78:7707-15.
    • (2006) Anal Chem , vol.78 , pp. 7707-7715
    • Orte, A.1    Clarke, R.2    Balasubramanian, S.3    Klenerman, D.4
  • 51
    • 34247151600 scopus 로고    scopus 로고
    • Optimized threshold selection for single-molecule two-color fluorescence coincidence spectroscopy
    • Clarke RW, Orte A, Klenerman D. Optimized threshold selection for single-molecule two-color fluorescence coincidence spectroscopy. Anal Chem 2007; 79:2771-7.
    • (2007) Anal Chem , vol.79 , pp. 2771-2777
    • Clarke, R.W.1    Orte, A.2    Klenerman, D.3
  • 52
    • 38449086723 scopus 로고    scopus 로고
    • + T cell activation is governed by TCR-peptide/MHC affinity, not dissociation rate
    • + T cell activation is governed by TCR-peptide/MHC affinity, not dissociation rate. J Immunol 2007; 179:2952-60.
    • (2007) J Immunol , vol.179 , pp. 2952-2960
    • Tian, S.1    Maile, R.2    Collins, E.J.3    Frelinger, J.A.4
  • 53
    • 78650599246 scopus 로고    scopus 로고
    • Mechanisms for T cell receptor triggering
    • van der Merwe PA, Dushek O. Mechanisms for T cell receptor triggering. Nat Rev Immunol 2011; 11:47-55.
    • (2011) Nat Rev Immunol , vol.11 , pp. 47-55
    • van der Merwe, P.A.1    Dushek, O.2
  • 54
    • 0034028826 scopus 로고    scopus 로고
    • Surpassing the lateral resolution limit by a factor of two using structured illumination microscopy
    • Gustafsson MG. Surpassing the lateral resolution limit by a factor of two using structured illumination microscopy. J Microsc 2000; 198:82-7.
    • (2000) J Microsc , vol.198 , pp. 82-87
    • Gustafsson, M.G.1
  • 55
    • 24944539530 scopus 로고    scopus 로고
    • Nonlinear structured-illumination microscopy: wide-field fluorescence imaging with theoretically unlimited resolution
    • Gustafsson MG. Nonlinear structured-illumination microscopy: wide-field fluorescence imaging with theoretically unlimited resolution. Proc Natl Acad Sci U S A 2005; 102:13081-6.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 13081-13086
    • Gustafsson, M.G.1
  • 56
    • 65449189726 scopus 로고    scopus 로고
    • Super-resolution video microscopy of live cells by structured illumination
    • Kner P, Chhun BB, Griffis ER, Winoto L, Gustafsson MG. Super-resolution video microscopy of live cells by structured illumination. Nat Methods 2009; 6:339-42.
    • (2009) Nat Methods , vol.6 , pp. 339-342
    • Kner, P.1    Chhun, B.B.2    Griffis, E.R.3    Winoto, L.4    Gustafsson, M.G.5
  • 57
    • 0028460042 scopus 로고
    • Breaking the diffraction resolution limit by stimulated emission: stimulated-emission-depletion fluorescence microscopy
    • Hell SW, Wichmann J. Breaking the diffraction resolution limit by stimulated emission: stimulated-emission-depletion fluorescence microscopy. Opt Lett 1994; 19:780-2.
    • (1994) Opt Lett , vol.19 , pp. 780-782
    • Hell, S.W.1    Wichmann, J.2
  • 58
    • 0034682512 scopus 로고    scopus 로고
    • Fluorescence microscopy with diffraction resolution barrier broken by stimulated emission
    • Klar TA, Jakobs S, Dyba M, Egner A, Hell SW. Fluorescence microscopy with diffraction resolution barrier broken by stimulated emission. Proc Natl Acad Sci U S A 2000; 97:8206-10.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 8206-8210
    • Klar, T.A.1    Jakobs, S.2    Dyba, M.3    Egner, A.4    Hell, S.W.5
  • 59
    • 61449201752 scopus 로고    scopus 로고
    • STED microscopy reveals crystal colour centres with nanometric resolution
    • Rittweger E, Han KY, Irvine SE, Eggeling C, Hell SW. STED microscopy reveals crystal colour centres with nanometric resolution. Nat Photon 2009; 3:144-7.
    • (2009) Nat Photon , vol.3 , pp. 144-147
    • Rittweger, E.1    Han, K.Y.2    Irvine, S.E.3    Eggeling, C.4    Hell, S.W.5
  • 62
    • 61349094652 scopus 로고    scopus 로고
    • Direct observation of the nanoscale dynamics of membrane lipids in a living cell
    • Eggeling C, Ringemann C, Medda R et al. Direct observation of the nanoscale dynamics of membrane lipids in a living cell. Nature 2009; 457:1159-62.
    • (2009) Nature , vol.457 , pp. 1159-1162
    • Eggeling, C.1    Ringemann, C.2    Medda, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.