Accumulation of raft lipids in T-cell plasma membrane domains engaged in TCR signalling

EMBO Journal

Volumn 28, Issue 5, 2009, Pages 466-476

  Zech, Tobias ^a,e   Ejsing, Christer S ^b   Gaus, Katharina ^c,d   De Wet, Ben ^a   Shevchenko, Andrej ^b   Simons, Kai ^b   Harder, Thomas ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

^c UNIVERSITY OF NEW SOUTH WALES   (Australia)

^d PRINCE OF WALES HOSPITAL   (Australia)

^e BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

Author keywords

Lipid rafts; Plasma membrane domains; Quantitative shotgun lipidomics; TCR signalling

Indexed keywords

CHOLESTEROL; LIPID; LIPIDOME; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLSERINE; POLYUNSATURATED FATTY ACID; SPHINGOMYELIN; T LYMPHOCYTE RECEPTOR;

ARTICLE; CELL MEMBRANE; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; HUMAN; HUMAN CELL; LIPID COMPOSITION; LIPID RAFT; LIPID STORAGE; LIQUID; MODULATION; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN DOMAIN; SPECIES; T LYMPHOCYTE;

CHOLESTEROL; FATTY ACIDS, UNSATURATED; HUMANS; JURKAT CELLS; LYMPHOCYTE ACTIVATION; MEMBRANE LIPIDS; MEMBRANE MICRODOMAINS; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLETHANOLAMINES; PHOSPHATIDYLINOSITOLS; PHOSPHATIDYLSERINES; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, TRANSFERRIN; SIGNAL TRANSDUCTION; SPHINGOMYELINS; T-LYMPHOCYTES;

EID: 62049084949     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2009.6     Document Type: Article

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