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Volumn 12, Issue 1, 2012, Pages 169-174

Parthenolide, an inhibitor of the nuclear factor-κB pathway, ameliorates dextran sulfate sodium-induced colitis in mice

Author keywords

Dextran sulfate sodium induced colitis; Nuclear factor (NF) B; Parthenolide; Ulcerative colitis

Indexed keywords

I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MYELOPEROXIDASE; PARTHENOLIDE; PHOSPHOPROTEIN; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

EID: 84856089700     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2011.11.007     Document Type: Article
Times cited : (46)

References (39)
  • 1
    • 0037043658 scopus 로고    scopus 로고
    • Inflammatory bowel disease
    • DOI 10.1056/NEJMra020831
    • D.K. Podolsky Inflammatory bowel disease N Engl J Med 347 2002 417 429 (Pubitemid 34851835)
    • (2002) New England Journal of Medicine , vol.347 , Issue.6 , pp. 417-429
    • Podolsky, D.K.1
  • 2
    • 0033981670 scopus 로고    scopus 로고
    • Therapy of inflammatory bowel disease
    • B.E. Sands Therapy of inflammatory bowel disease Gastroenterology 118 2000 S68 S82
    • (2000) Gastroenterology , vol.118
    • Sands, B.E.1
  • 3
    • 0036088586 scopus 로고    scopus 로고
    • Advances in the medical therapy of inflammatory bowel disease
    • DOI 10.1097/00001574-200207000-00007
    • J.A. Katz Advances in the medical therapy of inflammatory bowel disease Curr Opin Gastroenterol 18 2002 435 440 (Pubitemid 34665102)
    • (2002) Current Opinion in Gastroenterology , vol.18 , Issue.4 , pp. 435-440
    • Katz, J.A.1
  • 4
    • 33751334334 scopus 로고    scopus 로고
    • Safety of Infliximab and Other Biologic Agents in the Inflammatory Bowel Diseases
    • DOI 10.1016/j.gtc.2006.09.008, PII S0889855306000847, Biologics abd Therapeutics of Inflamatory Bowel Disease
    • J.G. Reddy, and E.V. Loftus Jr. Safety of infliximab and other biologic agents in the inflammatory bowel diseases Gastroenterol Clin North Am 35 2006 837 855 (Pubitemid 44802970)
    • (2006) Gastroenterology Clinics of North America , vol.35 , Issue.4 , pp. 837-855
    • Reddy, J.G.1    Loftus Jr., E.V.2
  • 5
    • 0034005581 scopus 로고    scopus 로고
    • Role of cytokines in the pathogenesis of inflammatory bowel disease
    • DOI 10.1146/annurev.med.51.1.289
    • K.A. Papadakis, and S.R. Targan Role of cytokines in the pathogenesis of inflammatory bowel disease Annu Rev Med 51 2000 289 298 (Pubitemid 30216038)
    • (2000) Annual Review of Medicine , vol.51 , pp. 289-298
    • Papadakis, K.A.1    Targan, S.R.2
  • 6
    • 0031914778 scopus 로고    scopus 로고
    • Cytokines in inflammatory bowel disease
    • DOI 10.1007/s002689900401
    • G. Rogler, and T. Andus Cytokines in inflammatory bowel disease World J Surg 22 1998 382 389 (Pubitemid 28113526)
    • (1998) World Journal of Surgery , vol.22 , Issue.4 , pp. 382-389
    • Rogler, G.1    Andus, T.2
  • 7
    • 0026689516 scopus 로고
    • Tumor necrosis factor-a, interleukin-1, and interleukin-6 expression in inflammatory bowel disease
    • C. Stevens, G. Walz, C. Singaram, M.L. Lipman, B. Zanker, and A. Muggia Tumor necrosis factor-a, interleukin-1, and interleukin-6 expression in inflammatory bowel disease Dig Dis Sci 37 1992 818 826
    • (1992) Dig Dis Sci , vol.37 , pp. 818-826
    • Stevens, C.1    Walz, G.2    Singaram, C.3    Lipman, M.L.4    Zanker, B.5    Muggia, A.6
  • 9
    • 0028174061 scopus 로고
    • Function and activation of NF-κB in the immune system
    • P. Baeuerle, and T. Henkel Function and activation of NF-κB in the immune system Annu Rev Immunol 12 1994 141 153
    • (1994) Annu Rev Immunol , vol.12 , pp. 141-153
    • Baeuerle, P.1    Henkel, T.2
  • 10
    • 0029874138 scopus 로고    scopus 로고
    • The NF-kappa B and i kappa B proteins: New discoveries and insights
    • A.S. Baldwin The NF-kappa B and I kappa B proteins: new discoveries and insights Annu Rev Immunol 14 1996 649 683
    • (1996) Annu Rev Immunol , vol.14 , pp. 649-683
    • Baldwin, A.S.1
  • 11
    • 0031595210 scopus 로고    scopus 로고
    • Nuclear factor-κB is activated in macrophages and epithelial cells of inflamed intestinal mucosa
    • G. Rogler, K. Brand, D. Vogl, S. Page, R. Hofmeister, and T. Andus Nuclear factor-κB is activated in macrophages and epithelial cells of inflamed intestinal mucosa Gastroenterology 115 1998 537 569
    • (1998) Gastroenterology , vol.115 , pp. 537-569
    • Rogler, G.1    Brand, K.2    Vogl, D.3    Page, S.4    Hofmeister, R.5    Andus, T.6
  • 12
    • 0031925362 scopus 로고    scopus 로고
    • Activation of nuclear factor κB inflammatory bowel disease
    • S. Schreiber, S. Nikolaus, and J. Hampe Activation of nuclear factor-κB in inflammatory bowel disease Gut 42 1998 477 484 (Pubitemid 28186562)
    • (1998) Gut , vol.42 , Issue.4 , pp. 477-484
    • Schreiber, S.1    Nikolaus, S.2    Hampe, J.3
  • 13
    • 0029836444 scopus 로고    scopus 로고
    • Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-κB abrogates established experimental colitis in mice
    • DOI 10.1038/nm0996-998
    • M.F. Neurath, S. Pettersson, Z.U.M. Meyer, K.H. Büschenfelde, and W. Strober Local administration of antisense phosphorothioate oligonucleotide to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice Nat Med 2 1996 998 1004 (Pubitemid 26306838)
    • (1996) Nature Medicine , vol.2 , Issue.9 , pp. 998-1004
    • Neurath, M.F.1    Pettersson, S.2    Meyer Zum Buschenfelde, K.-H.3    Strober, W.4
  • 14
    • 27644453163 scopus 로고    scopus 로고
    • Treatment of murine Th1- and Th2-mediated inflammatory bowel disease with NF-κB decoy oligonucleotides
    • DOI 10.1172/JCI24792
    • S. Fichtner-Feigl, I.J. Fuss, J.C. Preiss, W. Strober, and A. Kitani Treatment of murine Th1- and Th2-mediated inflammatory bowel disease with NF-kappaB decoy oligonucleotides J Clin Invest 115 2005 3057 3071 (Pubitemid 41567571)
    • (2005) Journal of Clinical Investigation , vol.115 , Issue.11 , pp. 3057-3071
    • Fichtner-Feigl, S.1    Fuss, I.J.2    Preise, J.C.3    Strober, W.4    Kitani, A.5
  • 15
    • 66149083594 scopus 로고    scopus 로고
    • Amelioration of murine dextran sulfate sodium-induced colitis by nuclear factor-kappa b decoy oligonucleotides
    • J.Y. Xiang, L.G. Wu, X.L. Huang, M. Zhang, L. Pen, O. Ouyan, and H.T. Gan Amelioration of murine dextran sulfate sodium-induced colitis by nuclear factor-kappa b decoy oligonucleotides Am J Surg 197 2009 797 804
    • (2009) Am J Surg , vol.197 , pp. 797-804
    • Xiang, J.Y.1    Wu, L.G.2    Huang, X.L.3    Zhang, M.4    Pen, L.5    Ouyan, O.6    Gan, H.T.7
  • 17
    • 34249892217 scopus 로고    scopus 로고
    • Parthenolide inhibits IκB kinase, NF-κB activation, and inflammatory response in cystic fibrosis cells and mice
    • DOI 10.1165/rcmb.2006-0323OC
    • A. Saadane, S. Masters, J. DiDonato, J. Li, and M. Berger Parthenolide inhibits IκB kinase, NF-κB activation, and inflammatory response in cystic fibrosis cells and mice Am J Respir Cell Mol Biol 36 2007 728 736 (Pubitemid 46871428)
    • (2007) American Journal of Respiratory Cell and Molecular Biology , vol.36 , Issue.6 , pp. 728-736
    • Saadane, A.1    Masters, S.2    DiDonato, J.3    Li, J.4    Berger, M.5
  • 18
    • 42649142579 scopus 로고    scopus 로고
    • Inhibitory effects of parthenolide on antigen-induced microtubule formation and degranulation in mast cells
    • N. Miyata, Y. Gon, S. Nunomura, D. Endo, K. Yamashita, and K. Matsumoto Inhibitory effects of parthenolide on antigen-induced microtubule formation and degranulation in mast cells Int Immunopharmacol 8 2008 874 880
    • (2008) Int Immunopharmacol , vol.8 , pp. 874-880
    • Miyata, N.1    Gon, Y.2    Nunomura, S.3    Endo, D.4    Yamashita, K.5    Matsumoto, K.6
  • 20
    • 0033571108 scopus 로고    scopus 로고
    • The anti-inflammatory sesquiterpene lactone parthenolide inhibits NF-κB by targeting the IκB kinase complex
    • S.P. Hehner, T.G. Hofmann, W. Droge, and M.L. Schmitz The anti-inflammatory sesquiterpene lactone parthenolide inhibits NF-κB by targeting the IκB kinase complex J Immunol 163 1999 5617 5623
    • (1999) J Immunol , vol.163 , pp. 5617-5623
    • Hehner, S.P.1    Hofmann, T.G.2    Droge, W.3    Schmitz, M.L.4
  • 21
    • 0034879173 scopus 로고    scopus 로고
    • The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IκB kinase
    • DOI 10.1016/S1074-5521(01)00049-7, PII S1074552101000497
    • B.H.B. Kwok, B. Koh, M.I. Ndubuisi, M. Elofsson, and C.M. Crews The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IUB kinase Chem Biol 8 2001 759 766 (Pubitemid 32752455)
    • (2001) Chemistry and Biology , vol.8 , Issue.8 , pp. 759-766
    • Kwok, B.H.B.1    Koh, B.2    Ndubuisi, M.I.3    Elofsson, M.4    Crews, C.M.5
  • 22
    • 0035797147 scopus 로고    scopus 로고
    • Inhibition of interleukin-12 production in lipopolysaccharide-activated mouse macrophages by parthenolide, a predominant sesquiterpene lactone in Tanacetum parthenium: Involvement of nuclear factor-κB
    • DOI 10.1016/S0165-2478(01)00211-5, PII S0165247801002115
    • B.Y. Kang, S.W. Chung, and T.S. Kim Inhibition of interleukin-12 production in lipopolysaccharide-activated mouse macrophages by parthenolide, a predominant sesquiterpene lactone in Tanacetum parthenium: involvement of nuclear factor-κB Immunol Lett 77 2001 159 163 (Pubitemid 32532070)
    • (2001) Immunology Letters , vol.77 , Issue.3 , pp. 159-163
    • Kang, B.Y.1    Chung, S.W.2    Kim, T.S.3
  • 25
    • 0036278884 scopus 로고    scopus 로고
    • Dichotomal role of inhibition of p38 MAPK with SB 203580 in experimental colitis
    • DOI 10.1136/gut.50.4.507
    • T. ten Hove, B. van den Blink, I. Pronk, P. Drillenburg, M.P. Peppelenbosch, and S.J.H. van Deventer Dichotomal role of inhibition of p38 MAPK with SB 203580 in experimental colitis Gut 50 2002 507 512 (Pubitemid 34638870)
    • (2002) Gut , vol.50 , Issue.4 , pp. 507-512
    • Ten Hove, T.1    Van Den Blink, B.2    Pronk, I.3    Drillenburg, P.4    Peppelenbosch, M.P.5    Van Deventer, S.J.H.6
  • 26
    • 0025181580 scopus 로고
    • A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice
    • I. Okayasu, S. Hatakeyama, M. Yamada, T. Ohkusa, Y. Inagaki, and R. Nakaya A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice Gastroenterology 98 1990 694 702 (Pubitemid 20069706)
    • (1990) Gastroenterology , vol.98 , Issue.3 , pp. 694-702
    • Okayasu, I.1    Hatakeyama, S.2    Yamada, M.3    Ohkusa, T.4    Inagaki, Y.5    Nakaya, R.6
  • 28
    • 0036484004 scopus 로고    scopus 로고
    • Sesquiterpene lactone parthenolide, an inhibitor of I[kappa]B kinase complex and nuclear factor-[kappa]B, exerts beneficial effects in myocardial reperfusion injury
    • B. Zingarelli, P.W. Hake, A. Denenberg, and H.R. Wong Sesquiterpene lactone parthenolide, an inhibitor of I[kappa]B kinase complex and nuclear factor-[kappa]B, exerts beneficial effects in myocardial reperfusion injury Shock 17 2002 127 134
    • (2002) Shock , vol.17 , pp. 127-134
    • Zingarelli, B.1    Hake, P.W.2    Denenberg, A.3    Wong, H.R.4
  • 29
    • 77958561665 scopus 로고    scopus 로고
    • Curcumin protects intestinal mucosal barrier function of rat enteritis via activation of MKP-1 and attenuation of p38 and NF-κB activation
    • W.B. Song, Y.Y. Wang, F.S. Meng, Q.H. Zhang, J.Y. Zeng, and L.P. Xiao Curcumin protects intestinal mucosal barrier function of rat enteritis via activation of MKP-1 and attenuation of p38 and NF-κB activation PLoS One 5 2010 e12969
    • (2010) PLoS One , vol.5 , pp. 12969
    • Song, W.B.1    Wang, Y.Y.2    Meng, F.S.3    Zhang, Q.H.4    Zeng, J.Y.5    Xiao, L.P.6
  • 30
    • 27144554627 scopus 로고    scopus 로고
    • Prevention of the ultraviolet B-mediated skin photoaging by a nuclear factor κB inhibitor, parthenolide
    • DOI 10.1124/jpet.105.088674
    • K. Tanaka, J. Hasegawa, K. Asamitsu, and T. Okamoto Prevention of the ultraviolet B-mediated skin photoaging by a nuclear factor-κB inhibitor, parthenolide J Pharmacol Exp Ther 315 2005 624 630 (Pubitemid 41500727)
    • (2005) Journal of Pharmacology and Experimental Therapeutics , vol.315 , Issue.2 , pp. 624-630
    • Tanaka, K.1    Hasegawa, J.2    Asamitsu, K.3    Okamoto, T.4
  • 31
    • 0036237368 scopus 로고    scopus 로고
    • Parthenolide, an inhibitor of the nuclear factor-κB pathway, ameliorates cardiovascular derangement and outcome in endotoxic shock in rodents
    • DOI 10.1124/mol.61.5.953
    • M. Sheehan, H.R. Wong, P.W. Hake, V. Malhotra, M. O'Connor, and B. Zingarelli Parthenolide, an inhibitor of the nuclear factor-κB pathway, ameliorates cardiovascular derangement and outcome in endotoxic shock in rodents Mol Pharmacol 61 2002 953 963 (Pubitemid 34441759)
    • (2002) Molecular Pharmacology , vol.61 , Issue.5 , pp. 953-963
    • Sheehan, M.1    Wong, H.R.2    Hake, P.W.3    Malhotra, V.4    O'Connor, M.5    Zingarelli, A.6
  • 32
    • 0035218631 scopus 로고    scopus 로고
    • Macrophage control of inflammation: Negative pathways of regulation of inflammatory cytokines
    • A. Mantovani, M. Muzio, C. Garlanda, S. Sozzani, and P. Allavena Macrophage control of inflammation: negative pathways of regulation of inflammatory cytokines Novartis Found Symp 234 2001 120 131
    • (2001) Novartis Found Symp , vol.234 , pp. 120-131
    • Mantovani, A.1    Muzio, M.2    Garlanda, C.3    Sozzani, S.4    Allavena, P.5
  • 33
    • 0028867899 scopus 로고
    • Immunosuppression by glucocorticoids: Inhibition of NF-kappa B activity through induction of i kappa B synthesis
    • N. Auphan, J.A. DiDonato, C. Rosette, A. Helmberg, and M. Karin Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis Science 270 1995 286 290
    • (1995) Science , vol.270 , pp. 286-290
    • Auphan, N.1    Didonato, J.A.2    Rosette, C.3    Helmberg, A.4    Karin, M.5
  • 34
    • 0034322370 scopus 로고    scopus 로고
    • Suppression of NF-kappa B activity by sulfasalazine is mediated by direct inhibition of IkappaB kinases alpha and beta
    • C.K. Weber, S. Liptay, T. Wirth, G. Adler, and R.M. Schmid Suppression of NF-kappa B activity by sulfasalazine is mediated by direct inhibition of IkappaB kinases alpha and beta Gastroenterology 119 2000 1209 1218
    • (2000) Gastroenterology , vol.119 , pp. 1209-1218
    • Weber, C.K.1    Liptay, S.2    Wirth, T.3    Adler, G.4    Schmid, R.M.5
  • 35
    • 33747641679 scopus 로고    scopus 로고
    • Novel strategies for the treatment of inflammatory bowel disease: Selective inhibition of cytokines and adhesion molecules
    • K. Nakamura, K. Honda, T. Mizutani, H. Akiho, and N. Harada Novel strategies for the treatment of inflammatory bowel disease: selective inhibition of cytokines and adhesion molecules World J Gastroenterol 12 2006 4628 4635 (Pubitemid 44269718)
    • (2006) World Journal of Gastroenterology , vol.12 , Issue.29 , pp. 4628-4635
    • Nakamura, K.1    Honda, K.2    Mizutani, T.3    Akiho, H.4    Harada, N.5
  • 36
    • 0042140583 scopus 로고    scopus 로고
    • Parthenolide improves systemic hemodynamics and decreases tissue leukosequestration in rats with polymicrobial sepsis
    • DOI 10.1097/01.CCM.0000085186.14867.F7
    • M. Sheehan, H.R. Wong, P.W. Hake, and B. Zingarelli Parthenolide improves systemic hemodynamics and decreases tissue leukosequestration in rats with polymicrobial sepsis Crit Care Med 31 2003 2263 2270 (Pubitemid 37100827)
    • (2003) Critical Care Medicine , vol.31 , Issue.9 , pp. 2263-2270
    • Sheehan, M.1    Wong, H.R.2    Hake, P.W.3    Zingarelli, B.4
  • 37
    • 6044240634 scopus 로고    scopus 로고
    • Antitumor agent parthenolide reverses resistance of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through sustained activation of c-Jun N-terminal kinase
    • DOI 10.1038/sj.onc.1207995
    • H. Nakshatri, S.E. Rice, and P. Bhat-Nakshatri Antitumor agent parthenolide reverses resistance of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through sustained activation of c-Jun N-terminal kinase Oncogene 23 2004 7330 7344 (Pubitemid 39382136)
    • (2004) Oncogene , vol.23 , Issue.44 , pp. 7330-7344
    • Nakshatri, H.1    Rice, S.E.2    Bhat-Nakshatri, P.3
  • 39
    • 0023752998 scopus 로고
    • Randomized double-blind placebo-controlled trial of feverfew in migraine prevention
    • J.J. Murphy, S. Heptinstall, and J.R. Mitchell Randomized double-blind placebo-controlled trial of feverfew in migraine prevention Lancet 2 1988 189 192
    • (1988) Lancet , vol.2 , pp. 189-192
    • Murphy, J.J.1    Heptinstall, S.2    Mitchell, J.R.3


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