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Volumn 118, Issue 2 SUPPL., 2000, Pages

Therapy of inflammatory bowel disease

Author keywords

[No Author keywords available]

Indexed keywords

ALICAFORSEN; ANTIBIOTIC AGENT; AZATHIOPRINE; BIOLOGICAL RESPONSE MODIFIER; CIPROFLOXACIN; CORTICOSTEROID; CYCLOSPORIN; HEPARIN; IMMUNOMODULATING AGENT; INFLIXIMAB; INTERLEUKIN 10; INTERLEUKIN 11; MERCAPTOPURINE; MESALAZINE; METHOTREXATE; METRONIDAZOLE; NICOTINE; THALIDOMIDE; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

EID: 0033981670     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0016-5085(00)70007-2     Document Type: Article
Times cited : (229)

References (144)
  • 1
    • 0026432216 scopus 로고
    • Inflammatory bowel disease (1)
    • DK. Podolsky Inflammatory bowel disease (1) N Engl J Med 325 1991 928 937
    • (1991) N Engl J Med , vol.325 , pp. 928-937
    • Podolsky, DK.1
  • 3
    • 0027369395 scopus 로고
    • Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
    • B Sadlack H Merz H Schorle A Schimpl AC Feller I. Horak Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene Cell 75 1993 253 261
    • (1993) Cell , vol.75 , pp. 253-261
    • Sadlack, B1    Merz, H2    Schorle, H3    Schimpl, A4    Feller, AC5    Horak, I.6
  • 4
    • 0030747245 scopus 로고    scopus 로고
    • Epithelial cells as sensors for microbial infection
    • MF Kagnoff L. Eckmann Epithelial cells as sensors for microbial infection J Clin Invest 100 1997 6 10
    • (1997) J Clin Invest , vol.100 , pp. 6-10
    • Kagnoff, MF1    Eckmann, L.2
  • 5
    • 0026032886 scopus 로고
    • Expression of class II molecules on intestinal epithelial cells in humans. Differences between normal and inflammatory bowel disease
    • L Mayer D Eisenhardt P Salomon W Bauer R Plous L. Piccinini Expression of class II molecules on intestinal epithelial cells in humans. Differences between normal and inflammatory bowel disease Gastroenterology 100 1991 3 12
    • (1991) Gastroenterology , vol.100 , pp. 3-12
    • Mayer, L1    Eisenhardt, D2    Salomon, P3    Bauer, W4    Plous, R5    Piccinini, L.6
  • 6
    • 85031474600 scopus 로고    scopus 로고
    • Antigen priming, not tolerance, with oral antigen administration in inflammatory bowel disease
    • L Chan L. Mayer Antigen priming, not tolerance, with oral antigen administration in inflammatory bowel disease Gastroenterology 110 1996 A881 (abstr)
    • (1996) Gastroenterology , vol.110 , pp. A881
    • Chan, L1    Mayer, L.2
  • 8
    • 0028178873 scopus 로고
    • Signals and signs for lymphocyte responses
    • CA Janeway K. Bottomly Signals and signs for lymphocyte responses Cell 76 1994 275 285
    • (1994) Cell , vol.76 , pp. 275-285
    • Janeway, CA1    Bottomly, K.2
  • 9
    • 0027362633 scopus 로고
    • Activated human B lymphocytes express three CTLA-4 counterreceptors that costimulate T-cell activation
    • VA Boussiotis GJ Freeman JG Gribben J Daley G Gray LM. Nadler Activated human B lymphocytes express three CTLA-4 counterreceptors that costimulate T-cell activation Proc Natl Acad Sci USA 90 1993 11059 11063
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11059-11063
    • Boussiotis, VA1    Freeman, GJ2    Gribben, JG3    Daley, J4    Gray, G5    Nadler, LM.6
  • 10
    • 0030029222 scopus 로고    scopus 로고
    • Blocking the CD40L-CD40 interaction in vivo specifically prevents the priming of T helper 1 cells through the inhibition of interleukin 12 secretion
    • E Stüber W Strober M. Neurath Blocking the CD40L-CD40 interaction in vivo specifically prevents the priming of T helper 1 cells through the inhibition of interleukin 12 secretion J Exp Med 183 1996 693 698
    • (1996) J Exp Med , vol.183 , pp. 693-698
    • Stüber, E1    Strober, W2    Neurath, M.3
  • 11
    • 0028065540 scopus 로고
    • Human Th1 and Th2 cells: functional properties, regulation of development and role in autoimmunity
    • M De Carli MM D’Elios G Zancuoghi S Romagnani G. Del Prete Human Th1 and Th2 cells: functional properties, regulation of development and role in autoimmunity Autoimmunity 18 1994 301 308
    • (1994) Autoimmunity , vol.18 , pp. 301-308
    • De Carli, M1    D’Elios, MM2    Zancuoghi, G3    Romagnani, S4    Del Prete, G.5
  • 12
    • 0031469894 scopus 로고    scopus 로고
    • Review article: how relevant to human inflammatory bowel disease are current animal models of intestinal inflammation?
    • RB. Sartor Review article: how relevant to human inflammatory bowel disease are current animal models of intestinal inflammation? Aliment Pharmacol Ther 11 1997 89 96 discussion 96–97
    • (1997) Aliment Pharmacol Ther , vol.11 , pp. 89-96
    • Sartor, RB.1
  • 13
    • 0031573593 scopus 로고    scopus 로고
    • A role for TNF-alpha and mucosal T helper-1 cytokines in the pathogenesis of Crohn’s disease
    • SE Plevy CJ Landers J Prehn NM Carramanzana RL Deem D Shealy A role for TNF-alpha and mucosal T helper-1 cytokines in the pathogenesis of Crohn’s disease J Immunol 159 1997 6276 6282
    • (1997) J Immunol , vol.159 , pp. 6276-6282
    • Plevy, SE1    Landers, CJ2    Prehn, J3    Carramanzana, NM4    Deem, RL5    Shealy, D6
  • 14
    • 0030209985 scopus 로고    scopus 로고
    • Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn’s disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5
    • + lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn’s disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5 J Immunol 157 1996 1261 1270
    • (1996) J Immunol , vol.157 , pp. 1261-1270
    • Fuss, IJ1    Neurath, M2    Boirivant, M3    Klein, JS4    de la Motte, C5    Strong, SA6    Fiocchi, C7    Strober, W.8
  • 16
    • 0029671118 scopus 로고    scopus 로고
    • Roles of IFN-gamma and IFN-alpha in IL-12-induced T helper cell-1 development
    • CA Wenner ML Guler SE Macatonia A O’Garra KM. Murphy Roles of IFN-gamma and IFN-alpha in IL-12-induced T helper cell-1 development J Immunol 156 1996 1442 1447
    • (1996) J Immunol , vol.156 , pp. 1442-1447
    • Wenner, CA1    Guler, ML2    Macatonia, SE3    O’Garra, A4    Murphy, KM.5
  • 17
    • 0033152023 scopus 로고    scopus 로고
    • IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn’s disease: expression and localization in intestinal mucosal cells
    • TT Pizarro MH Michie M Bentz J Woraratanadharm MF Smith Jr E Foley CA Moskalukca SJ Bickston F. Cominelli IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn’s disease: expression and localization in intestinal mucosal cells J Immunol 162 1999 6829 6835
    • (1999) J Immunol , vol.162 , pp. 6829-6835
    • Pizarro, TT1    Michie, MH2    Bentz, M3    Woraratanadharm, J4    Smith, MF5    Foley, E6    Moskalukca, CA7    Bickston, SJ8    Cominelli, F.9
  • 18
    • 0032607876 scopus 로고    scopus 로고
    • IL-18: a TH1-inducing, proinflammatory cytokine and new member of the IL-1 family
    • CA. Dinarello IL-18: a TH1-inducing, proinflammatory cytokine and new member of the IL-1 family J Allergy Clin Immunol 103 1999 11 24
    • (1999) J Allergy Clin Immunol , vol.103 , pp. 11-24
    • Dinarello, CA.1
  • 19
    • 0030048535 scopus 로고    scopus 로고
    • Differential modulation of B7-1 and B7-2 isoform expression on human monocytes by cytokines which influence the development of T helper cell phenotype
    • WD Creery F Diaz-Mitoma L Filion A. Kumar Differential modulation of B7-1 and B7-2 isoform expression on human monocytes by cytokines which influence the development of T helper cell phenotype Eur J Immunol 26 1996 1273 1277
    • (1996) Eur J Immunol , vol.26 , pp. 1273-1277
    • Creery, WD1    Diaz-Mitoma, F2    Filion, L3    Kumar, A.4
  • 20
    • 0024408824 scopus 로고
    • Two types of mouse T helper cell. IV. TH2 clones secrete a factor that inhibits cytokine production by TH1 clones
    • DF Fiorentino MW Bond TR. Mosmann Two types of mouse T helper cell. IV. TH2 clones secrete a factor that inhibits cytokine production by TH1 clones J Exp Med 170 1989 2081 2095
    • (1989) J Exp Med , vol.170 , pp. 2081-2095
    • Fiorentino, DF1    Bond, MW2    Mosmann, TR.3
  • 22
    • 0029319901 scopus 로고
    • TNF, immunity and inflammatory disease: lessons of the past decade
    • B. Beutler TNF, immunity and inflammatory disease: lessons of the past decade J Invest Med 43 1995 227 235
    • (1995) J Invest Med , vol.43 , pp. 227-235
    • Beutler, B.1
  • 23
    • 0032063661 scopus 로고    scopus 로고
    • Proteolytic enzymes in inflammatory bowel disease
    • TT MacDonald SLF. Pender Proteolytic enzymes in inflammatory bowel disease Inflamm Bowel Dis 4 1998 157 164
    • (1998) Inflamm Bowel Dis , vol.4 , pp. 157-164
    • MacDonald, TT1    Pender, SLF.2
  • 24
    • 0027982876 scopus 로고
    • Traffic signals for lymphocyte recirculation and leukocyte emigration
    • TA. Springer Traffic signals for lymphocyte recirculation and leukocyte emigration Cell 76 1994 301 314
    • (1994) Cell , vol.76 , pp. 301-314
    • Springer, TA.1
  • 26
    • 0031092633 scopus 로고    scopus 로고
    • Monoclonal antibodies specific for beta 7 integrin and mucosal addressin cell adhesion molecule-1 (MAdCAM-1) reduce inflammation in the colon of scid mice reconstituted with CD45RBhigh CD4+ T cells
    • + T cells J Immunol 158 1997 2099 2106
    • (1997) J Immunol , vol.158 , pp. 2099-2106
    • Picarella, D1    Hurlbut, P2    Rottman, J3    Shi, X4    Butcher, E5    Ringler, DJ.6
  • 28
    • 0025219580 scopus 로고
    • Clinical, biological, and endoscopic picture of attacks of Crohn’s disease. Evolution on prednisolone. Groupe d’Etude Therapeutique des Affections Inflammatoires Digestives
    • R Modigliani JY Mary JF Simon A Cortot JC Soule JP Gendre E. Rene Clinical, biological, and endoscopic picture of attacks of Crohn’s disease. Evolution on prednisolone. Groupe d’Etude Therapeutique des Affections Inflammatoires Digestives Gastroenterology 98 1990 811 818
    • (1990) Gastroenterology , vol.98 , pp. 811-818
    • Modigliani, R1    Mary, JY2    Simon, JF3    Cortot, A4    Soule, JC5    Gendre, JP6    Rene, E.7
  • 29
    • 0027959253 scopus 로고
    • Oxidants and free radicals in inflammatory bowel disease
    • MB. Grisham Oxidants and free radicals in inflammatory bowel disease Lancet 344 1994 859 861
    • (1994) Lancet , vol.344 , pp. 859-861
    • Grisham, MB.1
  • 30
    • 0018580664 scopus 로고
    • The effect of sulfasalazine and its active components on human polymorphonuclear leukocyte function in relation to ulcerative colitis
    • L Molin O. Stendahl The effect of sulfasalazine and its active components on human polymorphonuclear leukocyte function in relation to ulcerative colitis Acta Medica Scand 206 1979 451 457
    • (1979) Acta Medica Scand , vol.206 , pp. 451-457
    • Molin, L1    Stendahl, O.2
  • 31
    • 0024028280 scopus 로고
    • Inhibition of intestinal macrophage chemotaxis to leukotriene B4 by sulphasalazine, olsalazine, and 5-aminosalicylic acid
    • 4 by sulphasalazine, olsalazine, and 5-aminosalicylic acid Aliment Pharmacol Ther 2 1988 203 211
    • (1988) Aliment Pharmacol Ther , vol.2 , pp. 203-211
    • Nielsen, OH1    Verspaget, HW2    Elmgreen, J.3
  • 32
    • 0030831625 scopus 로고    scopus 로고
    • Effects of mesalamine on the hsp72 stress response in rat IEC-18 intestinal epithelial cells
    • GC Burress MW Musch DA Jurivich J Welk EB. Chang Effects of mesalamine on the hsp72 stress response in rat IEC-18 intestinal epithelial cells Gastroenterology 113 1997 1474 1479
    • (1997) Gastroenterology , vol.113 , pp. 1474-1479
    • Burress, GC1    Musch, MW2    Jurivich, DA3    Welk, J4    Chang, EB.5
  • 34
    • 0026081451 scopus 로고
    • Sulphasalazine and prednisone compared with sulphasalazine for treating active Crohn disease. A double-blind, randomized, multicenter trial
    • MC Rijk RA van Hogezand HJ van Lier JH. van Tongeren Sulphasalazine and prednisone compared with sulphasalazine for treating active Crohn disease. A double-blind, randomized, multicenter trial Ann Intern Med 114 1991 445 450
    • (1991) Ann Intern Med , vol.114 , pp. 445-450
    • Rijk, MC1    van Hogezand, RA2    van Lier, HJ3    van Tongeren, JH.4
  • 35
    • 0023920745 scopus 로고
    • Comparison of delayed release 5 aminosalicylic acid (mesalazine) and sulphasalazine in the treatment of mild to moderate ulcerative colitis relapse
    • SA Riley V Mani MJ Goodman ME Herd S Dutt LA. Turnberg Comparison of delayed release 5 aminosalicylic acid (mesalazine) and sulphasalazine in the treatment of mild to moderate ulcerative colitis relapse Gut 29 1988 669 674
    • (1988) Gut , vol.29 , pp. 669-674
    • Riley, SA1    Mani, V2    Goodman, MJ3    Herd, ME4    Dutt, S5    Turnberg, LA.6
  • 36
    • 0023906720 scopus 로고
    • Comparison of delayed-release 5-aminosalicylic acid (mesalazine) and sulfasalazine as maintenance treatment for patients with ulcerative colitis
    • SA Riley V Mani MJ Goodman ME Herd S Dutt LA. Turnberg Comparison of delayed-release 5-aminosalicylic acid (mesalazine) and sulfasalazine as maintenance treatment for patients with ulcerative colitis Gastroenterology 94 1988 1383 1389
    • (1988) Gastroenterology , vol.94 , pp. 1383-1389
    • Riley, SA1    Mani, V2    Goodman, MJ3    Herd, ME4    Dutt, S5    Turnberg, LA.6
  • 37
    • 0024587677 scopus 로고
    • Coated mesalazine (5-aminosalicylic acid) versus sulphasalazine in the treatment of active ulcerative colitis: a randomised trial
    • D. Rachmilewitz Coated mesalazine (5-aminosalicylic acid) versus sulphasalazine in the treatment of active ulcerative colitis: a randomised trial BMJ 298 1989 82 86
    • (1989) BMJ , vol.298 , pp. 82-86
    • Rachmilewitz, D.1
  • 38
    • 0028290322 scopus 로고
    • 5-ASA enema versus oral sulphasalazine in maintaining remission in ulcerative colitis
    • A Andreoli S Spinella S Levenstein C. Prantera 5-ASA enema versus oral sulphasalazine in maintaining remission in ulcerative colitis Ital J Gastroenterol 26 1994 121 125
    • (1994) Ital J Gastroenterol , vol.26 , pp. 121-125
    • Andreoli, A1    Spinella, S2    Levenstein, S3    Prantera, C.4
  • 42
    • 0027947501 scopus 로고
    • A randomized, double-blind, placebo-controlled trial of the oral mesalamine (5-ASA) preparation, Asacol, in the treatment of symptomatic Crohn’s colitis and ileocolitis
    • WJ Tremaine KW Schroeder JM Harrison AR. Zinsmeister A randomized, double-blind, placebo-controlled trial of the oral mesalamine (5-ASA) preparation, Asacol, in the treatment of symptomatic Crohn’s colitis and ileocolitis J Clin Gastroenterol 19 1994 278 282
    • (1994) J Clin Gastroenterol , vol.19 , pp. 278-282
    • Tremaine, WJ1    Schroeder, KW2    Harrison, JM3    Zinsmeister, AR.4
  • 45
    • 0030775667 scopus 로고    scopus 로고
    • Mesalamine in the maintenance treatment of Crohn’s disease: a meta-analysis adjusted for confounding variables
    • C Camma M Giunta M Rosselli M. Cottone Mesalamine in the maintenance treatment of Crohn’s disease: a meta-analysis adjusted for confounding variables Gastroenterology 113 1997 1465 1473
    • (1997) Gastroenterology , vol.113 , pp. 1465-1473
    • Camma, C1    Giunta, M2    Rosselli, M3    Cottone, M.4
  • 46
    • 0018073068 scopus 로고
    • Radiologic and clinical assessment of broad-spectrum antibiotic therapy in Crohn’s disease
    • AA Moss JV Carbone HY. Kressel Radiologic and clinical assessment of broad-spectrum antibiotic therapy in Crohn’s disease AJR Am J Roentgenol 131 1978 787 790
    • (1978) AJR Am J Roentgenol , vol.131 , pp. 787-790
    • Moss, AA1    Carbone, JV2    Kressel, HY.3
  • 47
    • 0020541081 scopus 로고
    • Inhibition of delayed hypersensitivity by metronidazole and misonidazole
    • S Rockwell CG Irvin MH. Neaderland Inhibition of delayed hypersensitivity by metronidazole and misonidazole Int J Radiat Oncol Biol Phys 9 1983 701 706
    • (1983) Int J Radiat Oncol Biol Phys , vol.9 , pp. 701-706
    • Rockwell, S1    Irvin, CG2    Neaderland, MH.3
  • 48
    • 0029817190 scopus 로고    scopus 로고
    • Immunomodulatory action of levofloxacin on cytokine production by human peripheral blood mononuclear cells
    • T Yoshimura C Kurita E Usami T Nakao S Watanabe J Kobayashi F Yamazaki H. Nagai Immunomodulatory action of levofloxacin on cytokine production by human peripheral blood mononuclear cells Chemotherapy 42 1996 459 464
    • (1996) Chemotherapy , vol.42 , pp. 459-464
    • Yoshimura, T1    Kurita, C2    Usami, E3    Nakao, T4    Watanabe, S5    Kobayashi, J6    Yamazaki, F7    Nagai, H.8
  • 51
    • 0021264732 scopus 로고
    • Metronidazole therapy for Crohn’s disease and associated fistulae
    • J Jakobovits MM. Schuster Metronidazole therapy for Crohn’s disease and associated fistulae Am J Gastroenterol 79 1984 533 540
    • (1984) Am J Gastroenterol , vol.79 , pp. 533-540
    • Jakobovits, J1    Schuster, MM.2
  • 52
    • 0029079279 scopus 로고
    • Controlled trial of metronidazole treatment for prevention of Crohn’s recurrence after ileal resection
    • P Rutgeerts M Hiele K Geboes M Peeters F Penninckx R Aerts R. Kerremans Controlled trial of metronidazole treatment for prevention of Crohn’s recurrence after ileal resection Gastroenterology 108 1995 1617 1621
    • (1995) Gastroenterology , vol.108 , pp. 1617-1621
    • Rutgeerts, P1    Hiele, M2    Geboes, K3    Peeters, M4    Penninckx, F5    Aerts, R6    Kerremans, R.7
  • 53
    • 0032458052 scopus 로고    scopus 로고
    • Use of antibiotics in the treatment of active Crohn’s disease: experience with metronidazole and ciprofloxacin
    • C Prantera E Berto ML Scribano G. Falasco Use of antibiotics in the treatment of active Crohn’s disease: experience with metronidazole and ciprofloxacin Ital J Gastroenterol 30 1998 602 606
    • (1998) Ital J Gastroenterol , vol.30 , pp. 602-606
    • Prantera, C1    Berto, E2    Scribano, ML3    Falasco, G.4
  • 54
    • 0344457371 scopus 로고    scopus 로고
    • A controlled trial comparing ciprofloxacin with mesalazine for the treatment of active Crohn’s disease. Groupe d’Etudes Therapeutiques des Affections Inflammatoires Digestives (GETAID)
    • JF Colombel M Lemann M Cassagnou Y Bouhnik B Duclos JL Dupas B Notteghem JY. Mary A controlled trial comparing ciprofloxacin with mesalazine for the treatment of active Crohn’s disease. Groupe d’Etudes Therapeutiques des Affections Inflammatoires Digestives (GETAID) Am J Gastroenterol 94 1999 674 678
    • (1999) Am J Gastroenterol , vol.94 , pp. 674-678
    • Colombel, JF1    Lemann, M2    Cassagnou, M3    Bouhnik, Y4    Duclos, B5    Dupas, JL6    Notteghem, B7    Mary, JY.8
  • 55
    • 0031905237 scopus 로고    scopus 로고
    • Combination ciprofloxacin and metronidazole for active Crohn’s disease
    • SL Greenbloom AH Steinhart GR. Greenberg Combination ciprofloxacin and metronidazole for active Crohn’s disease Can J Gastroenterol 12 1998 53 56
    • (1998) Can J Gastroenterol , vol.12 , pp. 53-56
    • Greenbloom, SL1    Steinhart, AH2    Greenberg, GR.3
  • 57
    • 0022380401 scopus 로고
    • Intensive intravenous treatment of ulcerative colitis
    • G Jarnerot P Rolny H. Sandberg-Gertzen Intensive intravenous treatment of ulcerative colitis Gastroenterology 89 1985 1005 1013
    • (1985) Gastroenterology , vol.89 , pp. 1005-1013
    • Jarnerot, G1    Rolny, P2    Sandberg-Gertzen, H.3
  • 58
    • 0008690916 scopus 로고
    • Cortisone in ulcerative colitis. Final report on a therapeutic trial
    • SC Truelove LJ. Witts Cortisone in ulcerative colitis. Final report on a therapeutic trial BMJ 2 1955 1041 1048
    • (1955) BMJ , vol.2 , pp. 1041-1048
    • Truelove, SC1    Witts, LJ.2
  • 60
  • 61
    • 0031727193 scopus 로고    scopus 로고
    • Novel pathways for glucocorticoid effects on neutrophils in chronic inflammation
    • NJ Goulding HS Euzger SK Butt M. Perretti Novel pathways for glucocorticoid effects on neutrophils in chronic inflammation Inflamm Res 47 1998 S158 S165
    • (1998) Inflamm Res , vol.47 , pp. S158-S165
    • Goulding, NJ1    Euzger, HS2    Butt, SK3    Perretti, M.4
  • 62
    • 0030832266 scopus 로고    scopus 로고
    • Molecular mechanisms involved in the regulation of prostaglandin biosynthesis by glucocorticoids
    • M. Goppelt-Struebe Molecular mechanisms involved in the regulation of prostaglandin biosynthesis by glucocorticoids Biochem Pharmacol 53 1997 1389 1395
    • (1997) Biochem Pharmacol , vol.53 , pp. 1389-1395
    • Goppelt-Struebe, M.1
  • 63
    • 0028267896 scopus 로고
    • Frequency of glucocorticoid resistance and dependency in Crohn’s disease
    • P Munkholm E Langholz M Davidsen V. Binder Frequency of glucocorticoid resistance and dependency in Crohn’s disease Gut 35 1994 360 362
    • (1994) Gut , vol.35 , pp. 360-362
    • Munkholm, P1    Langholz, E2    Davidsen, M3    Binder, V.4
  • 64
    • 84948727924 scopus 로고
    • New steroids for inflammatory bowel disease
    • R. Lofberg New steroids for inflammatory bowel disease Inflamm Bowel Dis 1 1995 135 141
    • (1995) Inflamm Bowel Dis , vol.1 , pp. 135-141
    • Lofberg, R.1
  • 65
    • 0029931612 scopus 로고    scopus 로고
    • Rational design of novel immunosuppressive drugs: analogues of azathioprine lacking the 6-mercaptopurine substituent retain or have enhanced immunosuppressive effects
    • DJ Crawford JL Maddocks DN Jones P. Szawlowski Rational design of novel immunosuppressive drugs: analogues of azathioprine lacking the 6-mercaptopurine substituent retain or have enhanced immunosuppressive effects J Med Chem 39 1996 2690 2695
    • (1996) J Med Chem , vol.39 , pp. 2690-2695
    • Crawford, DJ1    Maddocks, JL2    Jones, DN3    Szawlowski, P.4
  • 66
    • 0018888679 scopus 로고
    • Treatment of Crohn’s disease with 6-mercaptopurine. A long-term, randomized, double-blind study
    • DH Present BI Korelitz N Wisch JL Glass DB Sachar BS. Pasternak Treatment of Crohn’s disease with 6-mercaptopurine. A long-term, randomized, double-blind study N Engl J Med 302 1980 981 987
    • (1980) N Engl J Med , vol.302 , pp. 981-987
    • Present, DH1    Korelitz, BI2    Wisch, N3    Glass, JL4    Sachar, DB5    Pasternak, BS.6
  • 67
    • 0029134702 scopus 로고
    • Azathioprine and 6-mercaptopurine in Crohn disease. A meta-analysis
    • DC Pearson GR May GH Fick LR. Sutherland Azathioprine and 6-mercaptopurine in Crohn disease. A meta-analysis Ann Intern Med 123 1995 132 142
    • (1995) Ann Intern Med , vol.123 , pp. 132-142
    • Pearson, DC1    May, GR2    Fick, GH3    Sutherland, LR.4
  • 69
    • 0000419269 scopus 로고    scopus 로고
    • Optimizing and individualizing 6-MP therapy in IBD: the role of 6-MP metabolite levels and TPMT genotyping
    • MC Dubinsky S Lamothe HY Yang S Targan D Sinnett Y Theoret E. Seidman Optimizing and individualizing 6-MP therapy in IBD: the role of 6-MP metabolite levels and TPMT genotyping Gastroenterology 116 1999 A702 (abstr)
    • (1999) Gastroenterology , vol.116 , pp. A702
    • Dubinsky, MC1    Lamothe, S2    Yang, HY3    Targan, S4    Sinnett, D5    Theoret, Y6    Seidman, E.7
  • 70
    • 0032998815 scopus 로고    scopus 로고
    • Molecular and cellular effects of methotrexate
    • M. Seitz Molecular and cellular effects of methotrexate Curr Opin Rheumatol 11 1999 226 232
    • (1999) Curr Opin Rheumatol , vol.11 , pp. 226-232
    • Seitz, M.1
  • 73
    • 0031803678 scopus 로고    scopus 로고
    • Immunosuppresive agents: recent developments in molecular action and clinical application
    • DA Gerber CA Bonham AW. Thomson Immunosuppresive agents: recent developments in molecular action and clinical application Transplant Proc 30 1998 1573 1579
    • (1998) Transplant Proc , vol.30 , pp. 1573-1579
    • Gerber, DA1    Bonham, CA2    Thomson, AW.3
  • 76
    • 0027160429 scopus 로고
    • Rapid closure of Crohn’s disease fistulas with continuous intravenous cyclosporin A
    • SB Hanauer MB. Smith Rapid closure of Crohn’s disease fistulas with continuous intravenous cyclosporin A Am J Gastroenterol 88 1993 646 649 [see comments]
    • (1993) Am J Gastroenterol , vol.88 , pp. 646-649
    • Hanauer, SB1    Smith, MB.2
  • 79
    • 0029959419 scopus 로고    scopus 로고
    • Azathioprine is useful in maintaining long-term remission induced by intravenous cyclosporine in steroid-refractory severe ulcerative colitis
    • F Fernandez-Banares X Bertran M Esteve-Comas E Cabre M Menacho P Humbert R Planas MA. Gassull Azathioprine is useful in maintaining long-term remission induced by intravenous cyclosporine in steroid-refractory severe ulcerative colitis Am J Gastroenterol 91 1996 2498 2499
    • (1996) Am J Gastroenterol , vol.91 , pp. 2498-2499
    • Fernandez-Banares, F1    Bertran, X2    Esteve-Comas, M3    Cabre, E4    Menacho, M5    Humbert, P6    Planas, R7    Gassull, MA.8
  • 81
    • 0032455984 scopus 로고    scopus 로고
    • Neoral may be as effective as intravenous cyclosporine in the treatment of steroid-resistant ulcerative colitis
    • K Oppong CO. Record Neoral may be as effective as intravenous cyclosporine in the treatment of steroid-resistant ulcerative colitis Am J Gastroenterol 93 1998 1188 1189
    • (1998) Am J Gastroenterol , vol.93 , pp. 1188-1189
    • Oppong, K1    Record, CO.2
  • 82
    • 0028964310 scopus 로고
    • The mouse/human chimeric monoclonal antibody cA2 neutralizes TNF in vitro and protects transgenic mice from cachexia and TNF lethality in vivo
    • SA Siegel DJ Shealy MT Nakada J Le DS Woulfe L Probert G Kollias J Ghrayeb J Vilcek PE. Daddona The mouse/human chimeric monoclonal antibody cA2 neutralizes TNF in vitro and protects transgenic mice from cachexia and TNF lethality in vivo Cytokine 7 1995 251 259
    • (1995) Cytokine , vol.7 , pp. 251-259
    • Siegel, SA1    Shealy, DJ2    Nakada, MT3    Le, J4    Woulfe, DS5    Probert, L6    Kollias, G7    Ghrayeb, J8    Vilcek, J9    Daddona, PE.10
  • 83
    • 0029004771 scopus 로고
    • Chimeric anti-TNF monoclonal antibody cA2 binds recombinant transmembrane TNF-alpha and activates immune effector functions
    • BJ Scallon MA Moore H Trinh DM Knight J. Ghrayeb Chimeric anti-TNF monoclonal antibody cA2 binds recombinant transmembrane TNF-alpha and activates immune effector functions Cytokine 7 1995 251 259
    • (1995) Cytokine , vol.7 , pp. 251-259
    • Scallon, BJ1    Moore, MA2    Trinh, H3    Knight, DM4    Ghrayeb, J.5
  • 90
    • 4243213755 scopus 로고    scopus 로고
    • Long-term safety of infliximab (anti-TNFa antibody) in patients with rheumatoid arthritis: results of the ATTRACT trial
    • TF Schaible T Braakman P Marsters G. Harriman Long-term safety of infliximab (anti-TNFa antibody) in patients with rheumatoid arthritis: results of the ATTRACT trial Gastroenterology 116 1999 A813 (abstr)
    • (1999) Gastroenterology , vol.116 , pp. A813
    • Schaible, TF1    Braakman, T2    Marsters, P3    Harriman, G.4
  • 93
    • 0026000892 scopus 로고
    • Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression
    • R de Waal Malefyt J Haanen H Spits MG Roncarolo A te Velde C Figdor K Johnson R Kastetein H Yssel JE. deVries Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression J Exp Med 174 1991 915 924
    • (1991) J Exp Med , vol.174 , pp. 915-924
    • de Waal Malefyt, R1    Haanen, J2    Spits, H3    Roncarolo, MG4    te Velde, A5    Figdor, C6    Johnson, K7    Kastetein, R8    Yssel, H9    deVries, JE.10
  • 94
    • 0026607155 scopus 로고
    • IL-10 inhibits mitogen-induced T cell proliferation by selectively inhibiting macrophage costimulatory function
    • L Ding EM. Shevach IL-10 inhibits mitogen-induced T cell proliferation by selectively inhibiting macrophage costimulatory function J Immunol 148 1992 3133 3139
    • (1992) J Immunol , vol.148 , pp. 3133-3139
    • Ding, L1    Shevach, EM.2
  • 95
    • 0027239842 scopus 로고
    • IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression
    • L Ding PS Linsley LY Huang RN Germain EM. Shevach IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression J Immunol 151 1993 1224 1234
    • (1993) J Immunol , vol.151 , pp. 1224-1234
    • Ding, L1    Linsley, PS2    Huang, LY3    Germain, RN4    Shevach, EM.5
  • 97
    • 0029083269 scopus 로고
    • Interleukin-10 gene knock-out mice: a model of chronic inflammation
    • D Rennick N Davidson D. Berg Interleukin-10 gene knock-out mice: a model of chronic inflammation Clin Immunol Immunopathol 76 1995 S174 S178
    • (1995) Clin Immunol Immunopathol , vol.76 , pp. S174-S178
    • Rennick, D1    Davidson, N2    Berg, D.3
  • 99
    • 0000234097 scopus 로고    scopus 로고
    • Safety, tolerance and efficacy of multiple doses of subcutaneous interleukin-10 in mild to moderate active Crohn’s disease (STEMM-CD)
    • RN Fedorak A Gangl CO Elson P Rutgeerts S Schreiber G Wild S Hanauer SJH van Deventer P. Grint Safety, tolerance and efficacy of multiple doses of subcutaneous interleukin-10 in mild to moderate active Crohn’s disease (STEMM-CD) Gastroenterology 114 1998 A974 (abstr)
    • (1998) Gastroenterology , vol.114 , pp. A974
    • Fedorak, RN1    Gangl, A2    Elson, CO3    Rutgeerts, P4    Schreiber, S5    Wild, G6    Hanauer, S7    van Deventer, SJH8    Grint, P.9
  • 103
    • 0029839502 scopus 로고    scopus 로고
    • Protection of the small intestinal clonogenic stem cells from radiation-induced damage by pretreatment with interleukin 11 also increases murine survival time
    • CS. Potten Protection of the small intestinal clonogenic stem cells from radiation-induced damage by pretreatment with interleukin 11 also increases murine survival time Stem Cells 14 1996 452 459
    • (1996) Stem Cells , vol.14 , pp. 452-459
    • Potten, CS.1
  • 104
    • 0029835760 scopus 로고    scopus 로고
    • Protection by recombinant human interleukin-11 against experimental TNB-induced colitis in rats
    • BS Qiu CJ Pfeiffer JC Keith Jr. Protection by recombinant human interleukin-11 against experimental TNB-induced colitis in rats Dig Dis Sci 41 1996 1625 1630
    • (1996) Dig Dis Sci , vol.41 , pp. 1625-1630
    • Qiu, BS1    Pfeiffer, CJ2    Keith, JC3
  • 106
    • 4243825639 scopus 로고
    • rhIL-11 decreases the severity of acetic acid-induced colonic injury in rats
    • JC Keith Jr L Albert RG. Schaub rhIL-11 decreases the severity of acetic acid-induced colonic injury in rats Gastroenterology 106 1994 A708 (abstr)
    • (1994) Gastroenterology , vol.106 , pp. A708
    • Keith, JC1    Albert, L2    Schaub, RG.3
  • 112
    • 0030611915 scopus 로고    scopus 로고
    • Double-blind comparison of an oral Escherichia coli preparation and mesalazine in maintaining remission of ulcerative colitis
    • W Kruis E Schutz P Fric B Fixa G Judmaier M. Stolte Double-blind comparison of an oral Escherichia coli preparation and mesalazine in maintaining remission of ulcerative colitis Aliment Pharmacol Ther 11 1997 853 858
    • (1997) Aliment Pharmacol Ther , vol.11 , pp. 853-858
    • Kruis, W1    Schutz, E2    Fric, P3    Fixa, B4    Judmaier, G5    Stolte, M.6
  • 113
    • 0031443860 scopus 로고    scopus 로고
    • HA. Malchow Crohn’s disease and Escherichia coli .. A new approach in therapy to maintain remission of colonic Crohn’s disease? J Clin Gastroenterol 25 1997 653 658
    • (1997) J Clin Gastroenterol , vol.25 , pp. 653-658
    • Malchow, HA.1
  • 114
    • 0033592203 scopus 로고    scopus 로고
    • Non-pathogenic Escherichia coli versus mesalazine for the treatment of ulcerative colitis: a randomized trial
    • BJ Rembacken AM Snelling PM Hawkey DM Chalmers ATR. Axon Non-pathogenic Escherichia coli versus mesalazine for the treatment of ulcerative colitis: a randomized trial Lancet 354 1999 635 639
    • (1999) Lancet , vol.354 , pp. 635-639
    • Rembacken, BJ1    Snelling, AM2    Hawkey, PM3    Chalmers, DM4    Axon, ATR.5
  • 115
    • 0030968698 scopus 로고    scopus 로고
    • Preliminary report on the use of oral tacrolimus (FK506) in the treatment of complicated proximal small bowel and fistulizing Crohn’s disease
    • WJ. Sandborn Preliminary report on the use of oral tacrolimus (FK506) in the treatment of complicated proximal small bowel and fistulizing Crohn’s disease Am J Gastroenterol 92 1997 876 879
    • (1997) Am J Gastroenterol , vol.92 , pp. 876-879
    • Sandborn, WJ.1
  • 116
    • 0032447773 scopus 로고    scopus 로고
    • Steroid-unresponsive acute attacks of inflammatory bowel disease: immunomodulation by tacrolimus (FK506)
    • K Fellermann D Ludwig M Stahl T David-Walek EF. Stange Steroid-unresponsive acute attacks of inflammatory bowel disease: immunomodulation by tacrolimus (FK506) Am J Gastroenterol 93 1998 1860 1866
    • (1998) Am J Gastroenterol , vol.93 , pp. 1860-1866
    • Fellermann, K1    Ludwig, D2    Stahl, M3    David-Walek, T4    Stange, EF.5
  • 117
  • 118
    • 0033003888 scopus 로고    scopus 로고
    • Randomised trial of mycophenolate mofetil versus azathioprine for treatment of chronic active Crohn’s disease
    • MF Neurath R Wanitschke M Peters F Krummenauer KH Meyer zum Buschenfelde JF. Schlaak Randomised trial of mycophenolate mofetil versus azathioprine for treatment of chronic active Crohn’s disease Gut 44 1999 625 628
    • (1999) Gut , vol.44 , pp. 625-628
    • Neurath, MF1    Wanitschke, R2    Peters, M3    Krummenauer, F4    Meyer zum Buschenfelde, KH5    Schlaak, JF.6
  • 119
    • 0021739734 scopus 로고
    • Studies on the anti-inflammatory properties of thalidomide: effects on polymorphonuclear leukocytes and monocytes
    • RL Barnhill NJ Doll LE Millikan RC. Hastings Studies on the anti-inflammatory properties of thalidomide: effects on polymorphonuclear leukocytes and monocytes J Am Acad Dermatol 11 1984 814 819
    • (1984) J Am Acad Dermatol , vol.11 , pp. 814-819
    • Barnhill, RL1    Doll, NJ2    Millikan, LE3    Hastings, RC.4
  • 120
    • 0032100604 scopus 로고    scopus 로고
    • Inhibition of angiogenesis by thalidomide requires metabolic activation, which is species-dependent
    • KS Bauer SC Dixon WD. Figg Inhibition of angiogenesis by thalidomide requires metabolic activation, which is species-dependent Biochem Pharmacol 55 1998 1827 1834
    • (1998) Biochem Pharmacol , vol.55 , pp. 1827-1834
    • Bauer, KS1    Dixon, SC2    Figg, WD.3
  • 121
    • 0032714591 scopus 로고    scopus 로고
    • Thalidomide therapy for patients with refractory Crohn’s disease: an open-label trial
    • ED Ehrenpreis SV Kane LB Cohen SB Hanauer RD. Cohen Thalidomide therapy for patients with refractory Crohn’s disease: an open-label trial Gastroenterology 117 1999 1271 1277
    • (1999) , pp. 1271-1277
    • Ehrenpreis, ED1    Kane, SV2    Cohen, LB3    Hanauer, SB4    Cohen, RD.5
  • 123
    • 0031837706 scopus 로고    scopus 로고
    • Novel biological response modifiers derived from thalidomide
    • Y. Hashimoto Novel biological response modifiers derived from thalidomide Curr Med Chem 5 1998 163 178
    • (1998) Curr Med Chem , vol.5 , pp. 163-178
    • Hashimoto, Y.1
  • 126
    • 0003156149 scopus 로고    scopus 로고
    • IBD: a vascular disorder? The case for heparin therapy
    • JR. Korzenik IBD: a vascular disorder? The case for heparin therapy Inflamm Bowel Dis 3 1997 87 94
    • (1997) Inflamm Bowel Dis , vol.3 , pp. 87-94
    • Korzenik, JR.1
  • 133
    • 0030273769 scopus 로고    scopus 로고
    • Nicotine inhibits the in vitro production of interleukin 2 and tumour necrosis factor-alpha by human mononuclear cells
    • GS Madretsma GJ Donze AP van Dijk CJ Tak JH Wilson FJ. Zijlstra Nicotine inhibits the in vitro production of interleukin 2 and tumour necrosis factor-alpha by human mononuclear cells Immunopharmacology 35 1996 47 51
    • (1996) Immunopharmacology , vol.35 , pp. 47-51
    • Madretsma, GS1    Donze, GJ2    van Dijk, AP3    Tak, CJ4    Wilson, JH5    Zijlstra, FJ.6
  • 134
    • 0029913382 scopus 로고    scopus 로고
    • Colonic mucus, smoking and ulcerative colitis
    • RD. Pullan Colonic mucus, smoking and ulcerative colitis Ann R Coll Surg Engl 78 1996 85 91
    • (1996) Ann R Coll Surg Engl , vol.78 , pp. 85-91
    • Pullan, RD.1
  • 135
    • 0028143458 scopus 로고
    • Rat intestinal epithelial cells present major histocompatibility complex allopeptides to primed T cells
    • JM Brandeis MH Sayegh L Gallon RS Blumberg CS. Carpenter Rat intestinal epithelial cells present major histocompatibility complex allopeptides to primed T cells Gastroenterology 107 1994 1537 1542
    • (1994) Gastroenterology , vol.107 , pp. 1537-1542
    • Brandeis, JM1    Sayegh, MH2    Gallon, L3    Blumberg, RS4    Carpenter, CS.5
  • 136
    • 0029898878 scopus 로고    scopus 로고
    • Suppression of murine allergic contact dermatitis by CTLA4Ig. Tolerance induction of Th2 responses requires additional blockade of CD40-ligand
    • A Tang TA Judge BJ Nickoloff LA. Turka Suppression of murine allergic contact dermatitis by CTLA4Ig. Tolerance induction of Th2 responses requires additional blockade of CD40-ligand J Immunol 157 1996 117 125
    • (1996) J Immunol , vol.157 , pp. 117-125
    • Tang, A1    Judge, TA2    Nickoloff, BJ3    Turka, LA.4
  • 137
    • 0029878287 scopus 로고    scopus 로고
    • Therapeutic potential for blockade of the CD40 ligand, gp39
    • JE Buhlmann RJ. Noelle Therapeutic potential for blockade of the CD40 ligand, gp39 J Clin Immunol 16 1996 83 89
    • (1996) J Clin Immunol , vol.16 , pp. 83-89
    • Buhlmann, JE1    Noelle, RJ.2
  • 138
    • 0028861975 scopus 로고
    • Antibodies to interleukin 12 abrogate established experimental colitis in mice
    • MF Neurath I Fuss BL Kelsall E Stuber W. Strober Antibodies to interleukin 12 abrogate established experimental colitis in mice J Exp Med 182 1995 1281 1290
    • (1995) J Exp Med , vol.182 , pp. 1281-1290
    • Neurath, MF1    Fuss, I2    Kelsall, BL3    Stuber, E4    Strober, W.5
  • 139
    • 0029836444 scopus 로고    scopus 로고
    • Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice
    • MF Neurath S Pettersson KH Meyer zum Buschenfelde W. Strober Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice Nat Med 2 1996 998 1004
    • (1996) Nat Med , vol.2 , pp. 998-1004
    • Neurath, MF1    Pettersson, S2    Meyer zum Buschenfelde, KH3    Strober, W.4
  • 140
    • 0001010783 scopus 로고    scopus 로고
    • Role of reactive metabolites of oxygen and nitrogen in inflammatory bowel disease: toxins, mediators, and modulators of gene expression
    • EM Conner SJ Brand JM Davis DY Kang MB. Grisham Role of reactive metabolites of oxygen and nitrogen in inflammatory bowel disease: toxins, mediators, and modulators of gene expression Inflamm Bowel Dis 2 1996 133 147
    • (1996) Inflamm Bowel Dis , vol.2 , pp. 133-147
    • Conner, EM1    Brand, SJ2    Davis, JM3    Kang, DY4    Grisham, MB.5
  • 141
    • 0026579287 scopus 로고
    • Treatment of the mucosa with local anaesthetics in ulcerative colitis
    • S Bjorck A Dahlstrom L Johansson H. Ahlman Treatment of the mucosa with local anaesthetics in ulcerative colitis Agents Actions 1992 Spec No:C60–C72
    • (1992) Agents Actions
    • Bjorck, S1    Dahlstrom, A2    Johansson, L3    Ahlman, H.4
  • 142
    • 0030067726 scopus 로고    scopus 로고
    • Ropivacaine gel in active distal ulcerative colitis and proctitis—a pharmacokinetic and exploratory clinical study
    • E Arlander A Ost D Stahlberg R. Lofberg Ropivacaine gel in active distal ulcerative colitis and proctitis—a pharmacokinetic and exploratory clinical study Aliment Pharmacol Ther 10 1996 73 81
    • (1996) Aliment Pharmacol Ther , vol.10 , pp. 73-81
    • Arlander, E1    Ost, A2    Stahlberg, D3    Lofberg, R.4
  • 143
    • 0032981042 scopus 로고    scopus 로고
    • Novel therapies for inflammatory bowel disease
    • BE. Sands Novel therapies for inflammatory bowel disease Gastroenterol Clin North Am 28 1999 323 351
    • (1999) Gastroenterol Clin North Am , vol.28 , pp. 323-351
    • Sands, BE.1


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