Curcumin protects intestinal mucosal barrier function of rat enteritis via activation of MKP-1 and attenuation of p38 and NF-κB activation

PLoS ONE

Volumn 5, Issue 9, 2010, Pages

  Song, Wei Bing ^a   Wang, Yuan Yuan ^b   Meng, Fan Su ^c   Zhang, Qing Hua ^d   Zeng, Jian Ying ^a   Xiao, Li Ping ^a   Yu, Xin Pei ^a   Peng, Dan dan ^a   Su, Lei ^a   Xiao, Bing ^b   Zhang, Zhen Shu ^b  

^a GUANGZHOU GENERAL HOSPITAL OF GUANGZHOU MILITARY COMMAND   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

^c Department of Intensive Care Unit   (China)

^d 458 Hospital of People's Liberation Army   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE OXIDASE (COPPER CONTAINING); CURCUMIN; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 10; INTERLEUKIN 1BETA; LACTATE 2 MONOOXYGENASE; LIPOPOLYSACCHARIDE; METHOTREXATE; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; MYELOPEROXIDASE; SUPEROXIDE DISMUTASE; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR ALPHA; DUSP1 PROTEIN, RAT; MITOGEN ACTIVATED PROTEIN KINASE P38;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFICACY; DRUG MECHANISM; ENTERITIS; GENE ACTIVATION; GENE INACTIVATION; GENE LOCATION; GENE REPRESSION; INTESTINAL MUCOSA BARRIER; INTESTINE MUCOSA; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; RAT; TRANSCRIPTION REGULATION; WESTERN BLOTTING; ANIMAL; CELL LINE; DISEASE MODEL; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; RANDOMIZATION; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; CELL LINE; CURCUMIN; DISEASE MODELS, ANIMAL; DUAL SPECIFICITY PHOSPHATASE 1; ENTERITIS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTESTINAL MUCOSA; MICE; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY;

EID: 77958561665     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012969     Document Type: Article

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