Puerarin protects rat kidney from lead-induced apoptosis by modulating the PI3K/Akt/eNOS pathway

Toxicology and Applied Pharmacology

Volumn 258, Issue 3, 2012, Pages 330-342

  Liu, Chan Min ^a   Ma, Jie Qiong ^b   Sun, Yun Zhi ^a  

^a JIANGSU NORMAL UNIVERSITY   (China)

^b CHINA UNIVERSITY OF MINING AND TECHNOLOGY   (China)

Author keywords

Akt; Apoptosis; Kidney; Pb; Puerarin; ROS

Indexed keywords

CASPASE 3; CREATININE; CYTOCHROME C; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUTATHIONE; LEAD; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; PROTEIN KINASE B; PUERARIN; REACTIVE OXYGEN METABOLITE; UREA; URIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; HISTOPATHOLOGY; LIPID PEROXIDATION; MALE; NEPHROTOXICITY; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; RAT; RENAL PROTECTION; UREA BLOOD LEVEL;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE; IN SITU NICK-END LABELING; ISOFLAVONES; KIDNEY; LIPID PEROXIDATION; MALE; NITRIC OXIDE SYNTHASE TYPE III; ORGANOMETALLIC COMPOUNDS; OXIDATIVE STRESS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

RATTUS; RATTUS NORVEGICUS;

EID: 84855911161     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2011.11.015     Document Type: Article

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