Low level lead exposure and oxidative stress: Current opinions

Clinica Chimica Acta

Volumn 383, Issue 1-2, 2007, Pages 57-64

  Ahamed, M ^a   Siddiqui, M K J ^a  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

Author keywords

Antioxidants; Human diseases; Low level lead exposure; Oxidative stress; Reactive oxygen species

Indexed keywords

ANTIOXIDANT; DNA; LEAD;

BRAIN DAMAGE; COGNITIVE DEFECT; DEGENERATIVE DISEASE; EXPOSURE; GENITAL SYSTEM; HEALTH HAZARD; HEART INJURY; HUMAN; HYPERTENSION; KIDNEY DISEASE; KIDNEY INJURY; LIPID PEROXIDATION; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; SYSTEMATIC REVIEW;

DISEASE; ENVIRONMENTAL EXPOSURE; HUMANS; LEAD; LEAD POISONING; OXIDATION-REDUCTION; OXIDATIVE STRESS;

EID: 34347353159     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2007.04.024     Document Type: Review

References (78)

1. Spivey A. The weight of lead: effects add up in adults. Environ Health Perspect 115 (2007) A31-A36
2. Eisenberg D., Kessler R.C., Foster C., Norlock F.E., and Calkins D.R. Unconventional medicine in the US. Prevalence, costs and patterns of use. N Engl J Med 328 (1993) 246-252
3. Gogtay N.J., Bhatt H.A., Dalvi S.S., and Kshiragar N.A. The use and safety on non-allopathic Indian medicines. Drug Safety 25 (2002) 1005-1009
4. Thomas K.J., Coleman P., and Nicholl J.P. Trends in access to complementary or alternative medicines via primary care in England: 1995-2001 results of a follow-up national survey. Fam Pract 20 (2003) 575-577
5. CDC. Centre for disease control and prevention. Preventing lead poisoning in young children. A statement by the CDC (1991), US Dept. of Health and Human Services, Atlanta GA
6. Canfield R.L., Henderson C.R.J., Cory-Slechta D.A., Cox C., Jusko T.A., and Lanphear B.P. Intellectual impairment in children with blood lead concentrations below 10 microgram per deciliter. N Engl J Med 348 (2003) 1517-1526
7. Chiodo L.M., Jacobson S.W., and Jacobson J.L. Neurodevelopmental effects of postnatal lead exposure at very low levels. Neurotoxicol Teratol 26 (2004) 359-371
8. Courtois E., Marques M., and Barrientos A. Lead-induced down-regulation of soluble guanylate cyclase in isolated rat aortic segments mediated by reactive oxygen species and cyclo-oxygenase-2. J Am Soc Nephrol 14 (2003) 1464-1470
9. Ercal N., Neal R., Treeratphan P., et al. A role for oxidative stress in suppressing serum immunoglobulin levels in lead-exposed Fisher 344 rats. Arch Environ Contam Toxicol 39 (2000) 251-256
10. Farmand F., Ehdaie A., Roberts C.K., and Sindhu R.K. Lead-induced dysregulation of superoxide dismutase, catalase, glutathione peroxidase, and guanylate cyclase. Environ Res 98 (2005) 33-39
11. Ding Y., Gonic H.C., and Vaziri N.D. Lead promotes hydroxyl radical generation and lipid peroxidation in cultured aortic endothelial cells. Am J Hypertens 13 (2000) 552-555
12. Hunaitic A.A., and Sound M. Effect of lead concentration and level of glutathione S-transferase, reductase and peroxidase in human blood. Sci Total Environ 248 1 (2000) 45-50
13. Cabell L., Ferguson C., Luginbill D., Kern M., Weingart A., and Audesirk G. Differential induction of heme oxygenase and other stress proteins in cultured hippocampal astrocytes and neurons by inorganic lead. Toxicol Appl Pharmacol 98 (2004) 49-60
14. Fowler B.A., Whittaker M.H., Lipsky M., Wang G., and Chen X.O. Oxidative stress induced by lead, cadmium, and arsenic mixtures: 30 day, 90-day, and 180 day drinking water studies in rats: an overview. Biometals 17 (2004) 567-568
15. Costa C.A., Trivelato G.C., Pinto A.M.P., and Bechara E.J.H. Correlation between plasma 5-aminolevulinic acid concentrations and indicators of oxidative stress in lead-exposed workers. Clin Chem 43 (1997) 1196-02
16. Gurer-Orhan H., Sabir H.U., and Ozgunes H. Correlation between clinical indicator of lead poisoning and oxidative stress parameters in controls and lead exposed workers. Toxicology 195 (2004) 147-154
17. Kasperczyk S., Birkner E., Kasperczyk A., and Kasperczyk J. Lipid, lipid peroxidation and 7-ketocholesterol in workers exposed to lead. Human Exp Toxicol 24 (2005) 287-295
18. Muntener P., He J., Vupputuri S., Coresh J., and Batuman V. Blood lead and chronic kidney disease in the general United States population: results from NHANES III. Kidney Int 63 (2003) 1044-1050
19. Nash D., Magder L., Lustberg M., Sherwin R.W., Rubin R.J., and Kaufmann R.B. Blood lead, blood pressure, and hypertension perimenopausal and postmenopausal women. JAMA 289 (2003) 1523-1532
20. Navas-Acien A., Selvin E., Sharrett A.R., Calderon-Aranda E., Silbergeld E., and Gaullar E. Lead, cadmium, smoking, and increased risk of peripheral arterial disease. Circulation 109 (2004) 1196-01
21. Ekong E.B., Jaar B.G., and Weaver V.M. Lead-related nephrotoxicity: a review of epidemiologic evidence. Kindey Int 70 (2006) 2074-2084
22. Lee D.H., Lim J.S., Song K., Boo Y., and Jacobs Jr. D.R. Graded association of blood lead and urinary cadmium concentrations with oxidative stress related markers in the U.S. population: results from the third national health and nutrition examination survey. Environ Health Perspect 114 (2006) 350-354
23. Menke A., Muntner P., Batuman P., Silbergeld E.K., and Guallar E. Blood lead below 0.48 μg/dL (10 μg/dL) and mortality among US adults. Circulation 114 (2006) 1388-1394
24. Jacob B., Ritz B., Heinrich J., Hoelscher B., and Wichmann H.E. The effects of low level of blood lead on hematologic parameters in children. Environ Res 82 (2000) 150-159
25. Goering P.L. Lead-protein interactions as a basis for lead toxicity. Neurotoxicology 14 (1993) 45-60
26. Bergdahl I.A., Grubb A., Schutz A., et al. Lead binding to delta-aminolevulinic acid dehydratase in human erythrocytes. Pharmacol Toxicol 81 (1997) 153-158
27. Austrin K.H., Bishap D.F., Wetmur J.G., Kaul B.C., Davidow B., and Desnick R.J. Aminolevulinic acid dehydratase isozymes and lead toxicity. Ann NY Acad Sci 514 (1987) 23-29
28. Ahamed M., Verma S., Kumar A., and Siddiqui M.K.J. Environmental exposure to lead and its correlation with biochemical indices in children. Sci Total Environ 346 (2005) 48-55
29. Sakai T., and Morita Y. Delta-aminolevulinic acid in plasma or whole blood as a sensitive indicator of lead effects, and its relation to the other heme-related parameters. Int Arch Occup Environ Health 68 (1996) 126-132
30. Klaassen C.D. Casarett and Doul's toxicology: the basic science os poisons. 5th ed (1996), Pergamon Press, New York 705-709
31. Blumberg W.E., Eisinger J., Lamola A.A., and Zuckerman D.M. Principles and applications of hematofluorometry. J Clin Lab Autom 4 (1984) 29-42
32. Onalaja V.O., and Claudio L. Genetic susceptibility to lead poisoning. Environ Health Perspect 108 (2000) 23-28
33. 2+ promotes lipid peroxidation and alteration in membrane physical properties. Toxicology 132 (1999) 19-32
34. Bechara E.J.H. Lead poisoning and oxidative stress. Institute of de Quimica, Universidade de Sao Paulo, Brazil. SFRR`s 12th biennial meeting progamme and abstracts, May 5-9 (2004), Crown Plaza Panamericano Hotel Buenos Aires Argentina, S9-46. Free Radic Biol Med vol. 36 (2004) S22 pp.
35. Gurer H., Ozgunes H., Neal R., Spitz D.R., and Ercal N. Antioxidant effects of N-acetylcysteine and succimer in red blood cells from lead exposed rats. Toxicology 128 (1998) 181-189
36. Hsu P.C., Hsu C.C., Liu M.Y., Chen L.Y., and Guo Y.L. Lead-induced changes in spermatozoa function and metabolism. J Toxicol Environ Health 55 (1998) 45-64
37. Ding Y., Gonick H.C., Vaziri N.D., Liang K., and Wei L. Lead-induced hypertension III: increased hydroxyl radical production. Am J Hypertens 14 (2001) 169-173
38. Patra R.C., Swarup D., and Dwidedi S.K. Antioxidant effects of α-tocopherol, ascorbic acid and l-methionine on lead-induced oxidative stress of the liver, kidney and brain in rats. Toxicology 162 (2001) 81-88
39. Tandon S.K., Chatterjee M., Bhargava A., Shukla V., and Bihari V. Lead poisoning in Indian silver refiners. Sci Total Environ 281 (2001) 177-182
40. 2+ and 5-aminolevulinic acid-derived oxyradicals promote injury to isolated mitochondria. Free Radic Biol Med 19 (1995) 381-390
41. Bechara E.J.H. Oxidative stress in acute intermittent porphyria and lead poisoning may be triggered by 5-aminolevulinic acid. Braz J Med Biol Res 29 (1996) 841-851
42. Monteiro H.P., Abdalla D.S.P., Augusto O., and Bechara E.J.H. Free radical generation during delta-aminolevulinic acid auto-oxidation: induction by connections with porphyripathies. Arch Biochem Biophys 271 (1989) 206-216
43. Monteiro H.P., Abdalla D.S.P., Faljoni-Alario A., and Bechara E.J.H. Generation of active oxygen species during coupled auto-oxidation of oxyhemoglobin and delta-aminolevulinic acid. Arch Biochem Biophys 881 (1986) 100-106
44. Brennan M.J.W., Cantrill R.C., and Kramer S. Effect of 5-aminolevulinic acid on GABA receptor binding in synaptic plasma membranes. Int J Biochem 12 (1980) 833-835
45. Douki T., Onuki J., Medeiros M.H., Bechara E.J.H., Cadet J., and Di Mascio P. DNA alkylation by 4,5-dioxovaleric acid, the final oxidation product of 5-aminolevulinic acid. Chem Res Toxicol 11 (1998) 150-157
46. Douki T., Onuki J., Medeiros M.H., Bechara E.J.H., Cadet J., and Di Mascio P. Hydroxy radicals are involved in the oxidation of isolated and cellular DNA bases by 5-aminolevulinic acid. FEBS Lett 428 (1998) 93-96
47. 2+ ions. Biochim Biophys Acta 1225 (1994) 259-263
48. Hiraku Y., and Kawanishi S. Mechanism of oxidative DNA damage induced by 5-aminolevulinic acid in the presence of copper ion. Cancer Res 56 (1996) 1786-1793
49. Donaldson W.E., and Knowles S.O. Is lead toxicosis a reflection of altered fatty acid composition of membrane?. Comp Biochem Physiol C 104 (1993) 377-379
50. Leggett R.W. An age specific kinetic model of lead metabolism in humans. Environ Health Perspect 101 (1993) 598-616
51. Gurer H., and Ercal N. Can antioxidants be beneficial in the treatment of lead poisoning?. Free Radic Biol Med 29 (2000) 927-945
52. Yiin S.J., and Lin T.H. Lead-catalyzed peroxidation of essential unsaturated fatty acid. Biol Trace Elem Res 50 (1995) 167-172
53. Knowles S.O., and Donaldson W.E. Dietary modification of lead toxicity: effects on fatty acid and eicosanoid metabolism in chicks. Comp Biochem Physiol 95 (1990) 99-04
54. Lawton L., and Donaldson W.E. Lead-induced tissue fatty acid alterations and lipid peroxidation. Biol Trace Elem Res 28 (1991) 83-87
55. Sandhir R., and Gill K.D. Effect of lead on lipid peroxidation in liver of rats. Biol Trace Elem Res 21 (1995) 157-161
56. Michiels C., Raes M., Toussaint O., and Remacle J. Importance of Se-glutathione peroxidase, catalase and Cu/Zn SOD for cell survival against oxidative stress. Free Radic Biol Med 17 (1994) 235-248
57. Othman A.I., and El-Missiry M.A. Role of selenium against lead toxicity in male rats. J Biochem Mol Toxicol 12 (1998) 345-349
58. Whanger P.D. Selenium in the treatment of heavy metals poisoning and chemical carcinogenesis. J Trace Elem Electrolytes Health Dis 6 (1992) 209-221
59. Mylroie A.A., Collins H., Umbles C., and Kyle J. Erythrocyte superoxide dismutase activity and other parameters of copper status in rat ingesting lead acetate. Toxicol Appl Pharamcol 82 (1986) 512-520
60. Adler A.J., Barth R.H., and Berlyne G.M. Effect of lead on oxygen free radical metabolism: inhibition of superoxide dismutase activity. Trace Elem Med 10 (1993) 93-96
61. 2, superoxide dismutase, and xanthine oxidase. Environ Mol Mutagen 31 (1998) 352-361
62. + excretion. Human Exp Toxicol 22 (2003) 237-244
63. Ribarov S.R., Benov L.C., and Benchev I.C. The effect of lead on hemoglobin-catalyzed lipid peroxidation. Biochim Biophys Acta 664 (1981) 453-459
64. Hsu P.C., Liu M.Y., Hsu C.C., Chen L.Y., and Guo Y.L. Lead exposure causes generation of reactive oxygen species and functional impairment in rat sperm. Toxicology 122 (1997) 133-143
65. Batra N., Nehru B., and Bansal M.P. The effect of zinc supplementation on the effects of lead on the rat testis. Reprod Toxicol 12 (1998) 535-540
66. Siddiqui M.K.J., Sivastava S., and Mehrotra P.K. Environmental exposure to lead as a risk factor for prostate cancer. Biomed Environ Sci 15 (2002) 298-05
67. Ding Y., Vaziri N.D., and Gonick H.C. Lead-induced hypertension II: Response to sequential influsions of l-arginine, superoxide dismutase, and nitroprusside. Environ Res 76 (1998) 107-113
68. Vaziri N.D., and Ding Y. Effect of lead on nitric oxide synthase expression in coronary endothelial cells. Hypertension 37 (2001) 223-226
69. Ding Y., Gonick H.C., and Vaziri N.D. Lead promotes hydroxyl radical generation and lipid peroxidation in cultured aortic endothelial cells. Am J Hypertens 13 (2001) 552-555
70. Zelikoff J.T., Parsons E., and Schlesinger R.B. Inhalation of particulate lead oxide disrupts pulmonary macrophage-mediated functions important for host defense and tumor surveillance in the lung. Environ Res 62 (1993) 207-222
71. Skoczynska A., Smolik R., and Jelen M. Lipid abnormalities in rats given small doses of lead. Arch Toxicol 67 (1993) 200-204
72. Khalil-Manesh F., Gonick H.C., Weiler E.J., Prins B., Weber M.A., and Purdy R. Lead-induced hypertension: possible role of endothelial factors. Am J Hypertens 6 (1993) 723-729
73. Gonick H.C., Ding Y., Bondy S.C., Ni Z., and Vaziri N.D. Lead-induced hypertension I: interplay of nitric oxide and reactive oxygen species. Hypertension 30 (1997) 1487-1492
74. Dursun N., Dogan P., and Donmez H. Plasma and erythrocyte lipid peroxide levels in workers with occupational exposure to lead. Biol Trace Elem Res 82 (2001) 29-04
75. Ahamed M., Verma S., Kumar A., and Siddiqui M.K.J. Delta-aminolevulinic acid dehydratase inhibition and oxidative stress in relation to blood lead among urban adolescents. Human Exp Toxicol 25 (2006) 547-553
76. Schafer J.H., Glass T.A., Bressler J., Todd A.C., and Schwartz B.S. Blood lead is a predictor of homocysteine levels in a population-based study of older adults. Environ Health Perspect 113 (2005) 31-35
77. West W.L., Knight E.M., Edwards C.H., et al. Maternal low level lead and pregnancy outcomes. J Nutr 124 (1994) 981-986
78. Diouf A., Garcon G., Thiaw C., et al. Environmental lead exposure and its relationship to traffic density among Senegalese children: a cross sectional study. Human Exp Toxicol 25 (2006) 637-644