Antioxidative and hypocholesterolemic activities of water-soluble puerarin glycosides in HepG2 cells and in C57 BL/6J mice

European Journal of Pharmacology

Volumn 578, Issue 2-3, 2008, Pages 159-170

  Chung, Mi Ja ^a   Sung, Nak Ju ^b   Park, Cheon Seok ^c   Kweon, Dong Keon ^d   Mantovani, Alberto ^e   Moon, Tae Wha ^f   Lee, Sung Joon ^a   Park, Kwan Hwa ^f  

^a Institute of Biomedical Sciences and Food Safety   (South Korea)

^b Gyeongsang National University   (South Korea)

^c Kyung Hee University   (South Korea)

^d Kolon Life Science Inc   (South Korea)

^e ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^f Center for Agricultural Biomaterials   (South Korea)

Author keywords

Antioxidant; HMG CoA reductase; Low density lipoprotein receptor; Puerarin glycoside

Indexed keywords

ANTIOXIDANT; CHOLESTEROL; CHOLESTEROL 7ALPHA MONOOXYGENASE; GLYCOSIDE; HYDROXYL RADICAL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYPOCHOLESTEROLEMIC AGENT; ISOFLAVONE; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; PUERARIN; SCAVENGER; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL LIVER LEVEL; CHOLESTEROL METABOLISM; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; GLYCOSYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN TRANSPORT; TRANSCRIPTION INITIATION; TRANSLATION REGULATION; UPREGULATION;

ACYL COENZYME A; ANIMALS; ANTICHOLESTEREMIC AGENTS; CELL LINE, TUMOR; CHOLESTEROL; CHOLESTEROL 7-ALPHA-HYDROXYLASE; DOSE-RESPONSE RELATIONSHIP, DRUG; FREE RADICAL SCAVENGERS; FREE RADICALS; GLYCOSIDES; GLYCOSYLATION; HEPATOCYTES; HUMANS; ISOFLAVONES; LIVER; MICE; MICE, INBRED C57BL; RECEPTORS, LDL; RNA, MESSENGER; SOLUBILITY; SOLVENTS; TRANSCRIPTION, GENETIC; TRANSFECTION; WATER;

EID: 37349064399     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2007.09.036     Document Type: Article

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