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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 2, 2012, Pages 1130-1135

Tripeptidic BACE1 inhibitors devised by in-silico conformational structure-based design

(5) Hamada, Yoshio a,b Tagad, Harichandra D b Nishimura, Yoshinori b Ishiura, Shoichi c Kiso, Yoshiaki a,b,d

a KOBE GAKUIN UNIVERSITY (Japan)

b KYOTO PHARMACEUTICAL UNIVERSITY (Japan)

c UNIVERSITY OF TOKYO (Japan)

d NAGAHAMA INSTITUTE OF BIO SCIENCE AND TECHNOLOGY (Japan)

Author keywords

Secretase; Alzheimer's disease; BACE1; BACE1 inhibitor

Indexed keywords

BETA SECRETASE 1 INHIBITOR; BETA SECRETASE INHIBITOR; KMI 1068; KMI 1556; KMI 1563; KMI 1564; KMI 1565; KMI 1606; KMI 1607; KMI 1608; KMI 1609; KMI 1693; KMI 1694; KMI 1717; KMI 1718; KMI 1719; KMI 1723; KMI 1724; KMI 1726; KMI 1778; KMI 1840; KMI 1866; KMI 1879; KMI 1881; KMI 1883; KMI 1885; KMI 1886; KMI 1887; KMI 1895; KMI 1897; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; COMPUTER MODEL; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION;

AMYLOID PRECURSOR PROTEIN SECRETASES; ASPARTIC ACID ENDOPEPTIDASES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; ENZYME INHIBITORS; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; OLIGOPEPTIDES; RECOMBINANT PROTEINS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84855642846 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2011.11.102 Document Type: Article

Times cited : (21)

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