Comparison of central versus peripheral delivery of pregabalin in neuropathic pain states

Molecular Pain

Volumn 8, Issue , 2012, Pages

  Martinez, Jose A ^a   Kasamatsu, Manami ^a   Rosales Hernandez, Alma ^a   Hanson, Leah R ^b   Frey, William H ^b,c   Toth, Cory C ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b REGIONS HOSPITAL   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Diabetic peripheral neuropathy; Neuropathic pain; Pregabalin; Spinal nerve ligation

Indexed keywords

ALPHA2DELTA 1 SUBUNIT VOLTAGE GATED CALCIUM CHANNEL; MESSENGER RNA; PREGABALIN; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL; 4 AMINOBUTYRIC ACID; CACNA2D1 PROTEIN, RAT; CALCIUM CHANNEL; DRUG DERIVATIVE;

ALLODYNIA; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL DENSITY; CONTROLLED STUDY; DIABETIC NEUROPATHY; DRUG ABSORPTION; DRUG ACTIVITY; DRUG ADMINISTRATION ROUTE; DRUG DOSAGE FORM COMPARISON; DRUG EFFECT; DRUG MEGADOSE; DRUG TISSUE LEVEL; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; ISOTOPE LABELING; LOW DRUG DOSE; MALE; MICROGLIA; NEAR NERVE DRUG ADMINISTRATION; NERVE LIGATION; NEUROPATHIC PAIN; NONHUMAN; NUCLEOTIDE SEQUENCE; PERIPHERAL NERVE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT; RAT; SPINAL CORD DORSAL HORN; SPINAL GANGLION; TACTILE ALLODYNIA; THERMAL HYPERALGESIA; UPREGULATION; ANIMAL; ANIMAL BEHAVIOR; CENTRAL NERVOUS SYSTEM; COMPARATIVE STUDY; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; LIGATION; METABOLISM; NEURALGIA; PATHOLOGY; PERIPHERAL NERVOUS SYSTEM; REPRODUCIBILITY; SPINAL NERVE; SPINAL ROOT; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

ANIMALS; BEHAVIOR, ANIMAL; BLOTTING, WESTERN; CALCIUM CHANNELS; CENTRAL NERVOUS SYSTEM; DIABETIC NEUROPATHIES; DISEASE MODELS, ANIMAL; DRUG ADMINISTRATION ROUTES; GAMMA-AMINOBUTYRIC ACID; GANGLIA, SPINAL; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; LIGATION; MALE; MICROGLIA; NEURALGIA; PERIPHERAL NERVOUS SYSTEM; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; RNA, MESSENGER; SPINAL NERVE ROOTS; SPINAL NERVES;

EID: 84855573883     PISSN: None     EISSN: 17448069     Source Type: Journal    
DOI: 10.1186/1744-8069-8-3     Document Type: Article

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