Gabapentin may inhibit synaptic transmission in the mouse spinal cord dorsal horn through a preferential block of P/Q-type Ca2+ channels

Neuropharmacology

Volumn 46, Issue 5, 2004, Pages 743-749

  Bayer, Katharina ^a   Ahmadi, Seifollah ^a   Zeilhofer, Hanns Ulrich ^a  

^a UNIVERSITY HOSPITAL ERLANGEN   (Germany)

Author keywords

Calcium channel; Dorsal horn; Gabapentin; Pain; Spinal cord; Synaptic transmission

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; CALCIUM CHANNEL; CALCIUM CHANNEL P TYPE; CALCIUM CHANNEL Q TYPE; GABAPENTIN; GLUTAMIC ACID; GLYCINE; NEUROTRANSMITTER; OMEGA AGATOXIN IVA; OMEGA CONOTOXIN GVIA;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; EXCITATORY POSTSYNAPTIC POTENTIAL; FEMALE; INHIBITORY POSTSYNAPTIC POTENTIAL; MALE; MOUSE; NOCICEPTION; NONHUMAN; POSTSYNAPTIC INHIBITION; PRIORITY JOURNAL; SPINAL CORD DORSAL HORN; SYNAPTIC TRANSMISSION;

ACETIC ACIDS; AMINES; ANIMALS; CALCIUM CHANNELS, N-TYPE; CYCLOHEXANECARBOXYLIC ACIDS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GAMMA-AMINOBUTYRIC ACID; MALE; MICE; MICE, INBRED BALB C; NEURAL INHIBITION; POSTERIOR HORN CELLS; SPINAL CORD; SYNAPTIC TRANSMISSION;

EID: 1442299854     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2003.11.010     Document Type: Article

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