Protein kinase A-dependence of the supraspinally mediated analgesic effects of gabapentin on thermal and mechanical hypersensitivity

Journal of Pharmacological Sciences

Volumn 110, Issue 2, 2009, Pages 223-226

  Takasu, Keiko ^a   Kinoshita, Yu ^a   Ono, Hideki ^a   Tanabe, Mitsuo ^a  

^a NAGOYA CITY UNIVERSITY   (Japan)

Author keywords

Gabapentin; Neuropathic pain; Protein kinase A (PKA)

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; GABAPENTIN; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; GABAERGIC SYSTEM; GABAERGIC TRANSMISSION; KRUSKAL WALLIS TEST; LOCUS CERULEUS; MALE; MECHANICAL HYPERSENSITIVITY; MECHANICAL STIMULATION; MOUSE; NEUROPATHIC PAIN; NONHUMAN; SYNAPTIC TRANSMISSION; TEMPERATURE SENSITIVITY;

EID: 67649643438     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.09091SC     Document Type: Article

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