Thrombin induced connective tissue growth factor expression in rat vascular smooth muscle cells via the PAR-1/JNK/AP-1 pathway

Acta Pharmacologica Sinica

Volumn 33, Issue 1, 2012, Pages 49-56

  Ko, Wen Chin ^a,b   Chen, Bing Chang ^a   Hsu, Ming Jen ^c   Tsai, Chia Ti ^d   Hong, Chuang Ye ^a,e   Lin, Chien Huang ^a,e  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b CATHAY GENERAL HOSPITAL   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^e TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

activator protein 1 (AP 1); c Jun N terminal kinase (JNK); connective tissue growth factor; mitogen activated protein kinase (MAPK); protease activated receptor; thrombin; vascular smooth muscle cell

Indexed keywords

AMINO ACID RECEPTOR BLOCKING AGENT; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CONNECTIVE TISSUE GROWTH FACTOR; LUCIFERASE; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 4; SCH 79797; STRESS ACTIVATED PROTEIN KINASE; THROMBIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; GENETIC TRANSFECTION; MUSCLE CELL; NONHUMAN; PROTEIN EXPRESSION; RAT; RAT AORTIC SMOOTH MUSCLE CELL; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE CELL; WESTERN BLOTTING;

ANIMALS; CELL LINE; CONNECTIVE TISSUE GROWTH FACTOR; HEMOSTATICS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE SIGNALING SYSTEM; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; RATS; RECEPTOR, PAR-1; RECEPTORS, THROMBIN; THROMBIN; TRANSCRIPTION FACTOR AP-1;

EID: 84855417970     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2011.178     Document Type: Article

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