Connective tissue growth factor: What's in a name?

Molecular Genetics and Metabolism

Volumn 71, Issue 1-2, 2000, Pages 276-292

  Moussad, Essam El Din A ^a   Brigstock, David R ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR;

ANGIOGENESIS; APOPTOSIS; ATHEROSCLEROSIS; CELL ADHESION; CELL GROWTH; CELL MIGRATION; CELL PROLIFERATION; ENCHONDRAL OSSIFICATION; EXTRACELLULAR MATRIX; FIBROBLAST; FIBROSIS; GENE STRUCTURE; HUMAN; MITOSIS INHIBITION; NOMENCLATURE; PRIORITY JOURNAL; PROTEIN ANALYSIS; SCAR; SHORT SURVEY;

EID: 0033813903     PISSN: 10967192     EISSN: None     Source Type: Journal    
DOI: 10.1006/mgme.2000.3059     Document Type: Article

References (106)

1. Connective tissue growth factor: A cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10
2. Complexity of the early genetic response to growth factors in mouse fibroblasts
3. Structure, mapping and expression of fisp-12, a growth-factor-inducible gene encoding a secreted cysteine-rich protein
4. Identification of a gene family regulated by transforming growth factor-β
5. The modular architecture of a new family of growth regulators related to connective tissue growth factor
6. The connective tissue growth factor/cysteinerich 61/nephroblastoma overexpressed (CCN) family
7. The CCN family of angiogenic regulators: The integrin connection
8. Identification of a family of low-affinity insulin-like growth factor binding proteins (IGFBPs): Characterization of connective tissue growth factor as a member of the IGFBP superfamily
9. Recommendations for nomenclature of the insulin-like growth factor binding protein superfamily
10. How many insulin-like growth factor binding proteins?
11. CCN proteins are distinct from and should not be considered members of the insulin-like growth factor-binding protein superfamily
12. Proviral rearrangements and overexpression of a new cellular gene (nov) in myeloblastosis-associated virus type 1-induced nephroblastomas
13. Overexpression of connective tissue growth factor gene induces apoptosis in human aortic smooth muscle cells
14. Connective tissue growth factor induces apoptosis in human breast cancer cell line MCF-7
15. Connective tissue growth factor induces apoptosis via caspase 3 in cultured human aortic smooth muscle cells
16. Physical mapping of human loci homologous to the chicken nov protooncogene
17. A novel transforming growth factor beta response element controls the expression of the connective tissue growth factor gene
18. Differential expression of novH and CTGF in human glioma cell lines
19. Identification of glycosylated 38-kDa connective tissue growth factor (IGFBP-related protein 2) and proteolytic fragments in human biological fluids, and up-regulation of IGFBP-rP2 expression by TGF-beta in Hs 578T human breast cancer cells
20. Stimulation of fibroblast cell growth, matrix production, and granulation tissue formation by connective tissue growth factor
21. Purification and characterization of novel heparin-binding growth factors in uterine secretory fluids: Identification as heparin-regulated M(r) 10,000 forms of connective tissue growth factor
22. Characterization of 16- to 20-kilodalton (kDa) connective tissue growth factors (CTGFs) and demonstration of proteolytic activity for 38-kDa CTGF in pig uterine luminal flushings
23. Purification and characterization of connective tissue growth factor (CTGF) using heparin-affinity chromatography
24. Regulation of connective tissue growth factor activity in cultured rat mesangial cells and its expression in experimental diabetic glomerulosclerosis
25. Characterization of cell-associated and soluble forms of connective tissue growth factor (CTGF) produced by fibroblast cells in vitro
26. Localization of connective tissue growth factor during the period of embryo implantation in the mouse
27. Cyr61 and Fisp12 are both ECM-associated signaling molecules: Activities, metabolism, and localization during development
28. 1 and cell surface heparan sulfate proteoglycans
29. Immunohistochemical localization of connective tissue growth factor (CTGF) in the mouse embryo between days 7.5 and 14.5 of gestation
30. Connective tissue growth factor induces the proliferation, migration, and tube formation of vascular endothelial cells in vitro, and angiogenesis in vivo
31. Effects of CTGF/Hcs24, a hypertrophic chondrocyte-specific gene product, on the proliferation and differentiation of osteoblastic cells in vitro
32. Effects of CTGF/Hcs24, a product of a hypertrophic chondrocyte-specific gene, on the proliferation and differentiation of chondrocytes in culture
33. Messenger ribonucleic acids for MAC25 and connective tissue growth factor (CTGF) are inversely regulated during folliculogenesis and early luteogenesis
34. Suppression subtractive hybridization identifies high glucose levels as a stimulus for expression of connective tissue growth factor and other genes in human mesangial cells
35. Regulation of lysyl oxidase, collagen, and connective tissue growth factor by TGF-beta 1 and detection in human gingiva
36. Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis: A mouse fibrosis model
37. Induction of subcutaneous tissue fibrosis in newborn mice by transforming growth factor beta: Simultaneous application with basic fibroblast growth factor causes persistent fibrosis
38. Significant correlation between connective tissue growth factor gene expression and skin sclerosis in tissue sections from patients with systemic sclerosis
39. Connective tissue growth factor gene expression in tissue sections from localized scleroderma, keloid, and other fibrotic skin disorders
40. Serum levels of connective tissue growth factor are elevated in patients with systemic sclerosis: Association with extent of skin sclerosis and severity of pulmonary fibrosis
41. Pseudoscleroderma associated with lung cancer: Correlation of collagen type I and connective tissue growth factor gene expression
42. Establishment of the enzyme-linked immunosorbent assay for connective tissue growth factor (CTGF) and its detection in the sera of biliary atresia
43. Expression of connective tissue growth factor in experimental rat and human liver fibrosis
44. Increased expression of connective tissue growth factor in fibrotic human liver and in activated hepatic stellate cells
45. Cloning of partial cDNA of rat connective tissue growth factor and expression of its mRNA in experimental liver fibrosis
46. Expression of connective tissue growth factor in human renal fibrosis
47. Connective tissue growth factor: Just another factor in renal fibrosis?
48. Connective tissue growth factor: A potential stimulus for glomerulosclerosis and tubulointerstitial fibrosis in progressive renal disease
49. Connective tissue growth factor mRNA expression is upregulated in bleomycin-induced lung fibrosis
50. Enhanced insulin-like growth factor binding protein-related protein 2 (connective tissue growth factor) expression in patients with idiopathic pulmonary fibrosis and pulmonary sarcoidosis
51. Connective tissue growth factor. Friend or foe?
52. Human connective tissue growth factor is expressed in advanced atherosclerotic lesions
53. Increased expression of connective tissue growth factor in the infarct zone of experimentally induced myocardial infarction in rats
54. Connective tissue growth factor is a regulator for fibrosis in human chronic pancreatitis
55. Connective tissue growth factor: A novel regulator of mucosal repair and fibrosis in inflammatory bowel disease?
56. Role of transforming growth factor-beta in transdifferentiation and fibrosis of lens epithelial cells
57. Expression of connective tissue growth factor mRNA in the fibrous stroma of mammary tumors
58. Expression of fibrogenic cytokines in desmoplastic malignant melanoma
59. Differential expression of connective tissue growth factor gene in cutaneous fibrohistiocytic and vascular tumors
60. Expression and differential regulation of connective tissue growth factor in pancreatic cancer cells
61. Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair
62. Des-Arg(10)-kallidin engagement of the B1 receptor stimulates type I collagen synthesis via stabilization of connective tissue growth factor mRNA
63. Regulation of connective tissue growth factor expression by prostaglandin E(2)
64. Tumor necrosis factor alpha suppresses the induction of connective tissue growth factor by transforming growth factor-β in normal and scleroderma fibroblasts
65. Growth regulation in scleroderma fibroblasts: Increased response to transforming growth factor-β 1
66. New insights into hepatic stellate cell activation: The simple becomes complex
67. Profiling of genes which are differentially expressed in mouse liver in response to adenoviral vectors and delivered genes
68. Dexamethasone is a novel potent inducer of connective tissue growth factor expression: Implications for glucocorticoid therapy
69. Connective tissue growth factor mediates transforming growth factor-β-induced collagen synthesis: Down-regulation by cAMP
70. Transforming growth factor beta induces anchor-age-independent growth of NRK fibroblasts via a connective tissue growth factor-dependent signaling pathway
71. Inhibition of TGF-β-stimulated CTGF gene expression and anchorage-independent growth by cAMP identifies a CTGF-dependent restriction point in the cell cycle
72. CTGF modulates cell cycle progression in cAMP-arrested NRK fibroblasts
73. Connective tissue growth factor: A mediator of TGF-β action on fibroblasts
74. Novel intracellular effects of human connective tissue growth factor expressed in Cos-7 cells
75. Factor VIIa and thrombin induce the expression of Cyr61 and connective tissue growth factor, extracellular matrix signaling proteins that could act as possible downstream mediators in factor VIIa-tissue factor-induced signal transduction
76. Molecular cloning of genes differentially regulated by TNF-alpha in bovine aortic endothelial cells, fibroblasts and smooth muscle cells
77. Enhancement of cAMP levels and protein kinase activity by tumor necrosis factor and interleukin 1 in human fibroblasts: Role in the induction of interleukin 6
78. Expression of the growth factor-inducible immediate early gene cyr 61 correlates with chondrogenesis during mouse embryonic development
79. Cyr61, product of a growth factor-inducible immediate-early gene, regulates chondrogenesis in mouse limb bud mesenchymal cells
80. The immediate early gene product hCYR 61 localizes to the secretory pathway in human osteoblasts
81. Cloning of a mRNA preferentially expressed in chondrocytes by differential display-PCR from a human chondrocytic cell line that is identical with connective tissue growth factor (CTGF) mRNA
82. Demonstration of receptors specific for connective tissue growth factor on a human chondrocytic cell line (HCS-2/8)
83. Cloning the full-length cDNA for rat connective tissue growth factor: Implications for skeletal development
84. Gene expression during skeletal development in three osteopetrotic rat mutations
85. Regulation of mineral homeostasis in osteopetrotic (op) rats
86. Identification of newt connective tissue growth factor as a target of retinoid regulation in limb blastemal cells
87. Immunohistochemical detection of connective tissue growth factor during phases of urodele limb regeneration
88. Connective tissue growth factor (IGFBP-rP2) expression and regulation in cultured bovine endothelial cells
89. Inhibition of endogenous expression of connective tissue growth factor by its antisense oligonucleotide and antisense RNA suppresses proliferation and migration of vascular endothelial cells
90. Fisp12/mouse connective tissue growth factor mediates endothelial cell adhesion and migration through integrin α(v)β3, promotes endothelial cell survival, and induces angiogenesis in vivo
91. Cyr61, a product of a growth factor-inducible immediate early gene, promotes angiogenesis and tumor growth
92. Transforming growth factor-beta(I) induces apoptosis via connective tissue growth factor in human aortic smooth muscle cells
93. Regulation of programmed cell death or apoptosis in atherosclerosis
94. Activation-dependent adhesion of human platelets to Cyr61 and Fisp12/mouse connective tissue growth factor is mediated through integrin α(IIb)β 3
95. Differential gene expression in migrating renal epithelial cells after wounding
96. Calcium oxalate monohydrate crystals stimulate gene expression in renal epithelial cells
97. Connective tissue growth factor expression in the rat remnant kidney model and association with tubular epithelial cells undergoing transdifferentiation
98. Binding of factor VIIa to tissue factor on keratinocytes induces gene expression
99. Immunohistochemical localization of connective tissue growth factor in the rat central nervous system
100. Muscarinic acetylcholine receptors induce the expression of the immediate early growth regulatory gene Cyr61
101. Connective tissue growth factor: A novel player in tissue reorganization after brain injury?
102. TGF-β in the central nervous system: Potential roles of ischemic injury and neurodegenerative diseases
103. 1 and basic fibroblast growth factor in the injured CNS
104. Chromosomal mapping and expression of the human cyr 61 gene in tumour cells from the nervous system
105. Cyr61, a product of a growth factor-inducible immediate-early gene, promotes cell proliferation, migration, and adhesion
106. Adhesion of human umbilical vein endothelial cells to the immediate-early gene product Cyr61 is mediated through integrin α(v)β 3