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Volumn 67, Issue 1, 2005, Pages 2-11

The cardiovascular actions of protease-activated receptors

Author keywords

[No Author keywords available]

Indexed keywords

BMS 200261; G PROTEIN COUPLED RECEPTOR; N 3 AMINO 1 [[[(PHENYLMETHYL)AMINO]CARBONYL]PROPYL] ALPHA [[[[[1 (2,6 DICHLOROPHENYL)METHYL] 3 [1 PYRROLIDINYLMETHYL] 1 H INDOL 6 YL]AMINO]CARBONYL]AMINO] 3,4 DIFLUOROBENZENEPROPANAMIDE; PEPTIDE HYDROLASE INHIBITOR; PROTEINASE; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 2; PROTEINASE ACTIVATED RECEPTOR 3; PROTEINASE ACTIVATED RECEPTOR 4; RWJ 56110; THROMBIN; UNCLASSIFIED DRUG;

EID: 11244297746     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.104.003103     Document Type: Short Survey
Times cited : (108)

References (41)
  • 1
    • 0026568725 scopus 로고
    • Thrombin stimulates L-type calcium channels of guinea pig cardiomyocytes in cell-attached patches but not after intracellular dialysis
    • Albitz R, Droogmans G, Nilius B, and Casteels R (1992) Thrombin stimulates L-type calcium channels of guinea pig cardiomyocytes in cell-attached patches but not after intracellular dialysis. Cell Calcium 13:203-210.
    • (1992) Cell Calcium , vol.13 , pp. 203-210
    • Albitz, R.1    Droogmans, G.2    Nilius, B.3    Casteels, R.4
  • 2
    • 0033668989 scopus 로고    scopus 로고
    • Extracellular mutations of protease-activated receptor-1 result in differential activation by thrombin and thrombin receptor agonist peptide
    • Blackhart BD, Ruslim-Litrus L, Lu CC, Alves VL, Teng W, Scarborough RM, Reynolds EE, and Oksenberg D (2000) Extracellular mutations of protease-activated receptor-1 result in differential activation by thrombin and thrombin receptor agonist peptide. Mol Pharmacol 58:1178-1187.
    • (2000) Mol Pharmacol , vol.58 , pp. 1178-1187
    • Blackhart, B.D.1    Ruslim-Litrus, L.2    Lu, C.C.3    Alves, V.L.4    Teng, W.5    Scarborough, R.M.6    Reynolds, E.E.7    Oksenberg, D.8
  • 3
    • 0025367230 scopus 로고
    • Effect of thrombin on calcium homeostasis in chick embryonic heart cells
    • Chien WW, Mohabir R, and Clusin WT (1990) Effect of thrombin on calcium homeostasis in chick embryonic heart cells. J Clin Investig 85:1436-1443.
    • (1990) J Clin Investig , vol.85 , pp. 1436-1443
    • Chien, W.W.1    Mohabir, R.2    Clusin, W.T.3
  • 5
    • 0034671716 scopus 로고    scopus 로고
    • A polymorphic protease-activated receptor 2 (PAR2) displaying reduced sensitivity to trypsin and differential responses to PAR agonists
    • Compton SJ, Cairns JA, Palmer KJ, Al Ani B, Hollenberg MD, and Walls AF (2000) A polymorphic protease-activated receptor 2 (PAR2) displaying reduced sensitivity to trypsin and differential responses to PAR agonists. J Biol Chem 275:39207-39212.
    • (2000) J Biol Chem , vol.275 , pp. 39207-39212
    • Compton, S.J.1    Cairns, J.A.2    Palmer, K.J.3    Al Ani, B.4    Hollenberg, M.D.5    Walls, A.F.6
  • 6
    • 0036905071 scopus 로고    scopus 로고
    • Glycosylation of human proteinase-activated receptor-2 (HPAR2): Role in cell surface expression and signalling
    • Compton SJ, Sandhu S, Wijesuriya SJ, and Hollenberg MD (2002) Glycosylation of human proteinase-activated receptor-2 (HPAR2): role in cell surface expression and signalling. Biochem J 368:495-505.
    • (2002) Biochem J , vol.368 , pp. 495-505
    • Compton, S.J.1    Sandhu, S.2    Wijesuriya, S.J.3    Hollenberg, M.D.4
  • 7
    • 0034648757 scopus 로고    scopus 로고
    • Thrombin signalling and protease-activated receptors
    • Coughlin SR (2000) Thrombin signalling and protease-activated receptors. Nature (Lond) 407:258-264.
    • (2000) Nature (Lond) , vol.407 , pp. 258-264
    • Coughlin, S.R.1
  • 8
    • 0035979691 scopus 로고    scopus 로고
    • A role for thrombin receptor signaling in endothelial cells during embryonic development
    • Griffin CT, Srinivasan Y, Zheng YW, Huang W, and Coughlin SR (2001) A role for thrombin receptor signaling in endothelial cells during embryonic development. Science (Wash DC) 293:1666-1670.
    • (2001) Science (Wash DC) , vol.293 , pp. 1666-1670
    • Griffin, C.T.1    Srinivasan, Y.2    Zheng, Y.W.3    Huang, W.4    Coughlin, S.R.5
  • 9
    • 0028874584 scopus 로고
    • Human endothelial cell damage by neutrophil-derived cathepsin G. Role of cytoskeleton rearrangement and matrix-bound plasminogen activator inhihitor-1
    • Iacoviello L, Kolpakov V, Salvatore L, Amore C, Pintucci G, de Gaetano G, and Donati MB (1995) Human endothelial cell damage by neutrophil-derived cathepsin G. Role of cytoskeleton rearrangement and matrix-bound plasminogen activator inhihitor-1. Arterioscler Thromb Vasc Biol 15:2037-2046.
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 2037-2046
    • Iacoviello, L.1    Kolpakov, V.2    Salvatore, L.3    Amore, C.4    Pintucci, G.5    De Gaetano, G.6    Donati, M.B.7
  • 10
    • 0030060695 scopus 로고    scopus 로고
    • Arrhythmogenic action of thrombin during myocardial reperfusion via release of inositol 1,4,5-triphosphate
    • Jacobsen AN, Du XJ, Lambert KA, Dart AM, and Woodcock EA (1996) Arrhythmogenic action of thrombin during myocardial reperfusion via release of inositol 1,4,5-triphosphate. Circulation 93:23-26.
    • (1996) Circulation , vol.93 , pp. 23-26
    • Jacobsen, A.N.1    Du, X.J.2    Lambert, K.A.3    Dart, A.M.4    Woodcock, E.A.5
  • 11
    • 0344925961 scopus 로고    scopus 로고
    • Protease-activated receptor-4 uses dual prolines and an anionic retention motif for thrombin recognition and cleavage
    • Jacques SL and Kuliopulos A (2003) Protease-activated receptor-4 uses dual prolines and an anionic retention motif for thrombin recognition and cleavage. Biochem J 376:733-740.
    • (2003) Biochem J , vol.376 , pp. 733-740
    • Jacques, S.L.1    Kuliopulos, A.2
  • 12
    • 0032211802 scopus 로고    scopus 로고
    • The thrombin receptor elevates intracellular calcium in adult rat ventricular myocytes
    • Jiang T, Danilo P, and Steinberg SF (1998) The thrombin receptor elevates intracellular calcium in adult rat ventricular myocytes. J Mol Cell Cardiol 30:2193-2199.
    • (1998) J Mol Cell Cardiol , vol.30 , pp. 2193-2199
    • Jiang, T.1    Danilo, P.2    Steinberg, S.F.3
  • 15
    • 2442697694 scopus 로고    scopus 로고
    • Potent and metabolically stable agonists for protease-activated receptor-2: Evaluation of activity in multiple assay systems in vitro and in vivo
    • Kawabata A, Kanke T, Yonezawa D, Ishiki T, Saka M, Kabeya M, Sekiguchi F, Kubo S, Kuroda R, Iwaki M, et al. (2004) Potent and metabolically stable agonists for protease-activated receptor-2: evaluation of activity in multiple assay systems in vitro and in vivo. J Pharmacol Exp Ther 309:1098-1107.
    • (2004) J Pharmacol Exp Ther , vol.309 , pp. 1098-1107
    • Kawabata, A.1    Kanke, T.2    Yonezawa, D.3    Ishiki, T.4    Saka, M.5    Kabeya, M.6    Sekiguchi, F.7    Kubo, S.8    Kuroda, R.9    Iwaki, M.10
  • 16
    • 2442592928 scopus 로고    scopus 로고
    • Regulated shedding of PARI N-terminal exodomain from endothelial cells
    • Ludeman MJ, Zheng YW, Ishii K, and Coughlin SR (2004) Regulated shedding of PARI N-terminal exodomain from endothelial cells. J Biol Chem 279:18592-18599.
    • (2004) J Biol Chem , vol.279 , pp. 18592-18599
    • Ludeman, M.J.1    Zheng, Y.W.2    Ishii, K.3    Coughlin, S.R.4
  • 18
    • 0037783288 scopus 로고    scopus 로고
    • Extracellular mediators in atherosclerosis and thrombosis: Lessons from thrombin receptor knockout mice
    • Major CD, Santulli RJ, Derian CK, and Andrade-Gordon P (2003) Extracellular mediators in atherosclerosis and thrombosis: lessons from thrombin receptor knockout mice. Arterioscler Thromb Vasc Biol 23:931-939.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 931-939
    • Major, C.D.1    Santulli, R.J.2    Derian, C.K.3    Andrade-Gordon, P.4
  • 19
    • 0037040862 scopus 로고    scopus 로고
    • Protease-activated receptor-2 activation causes EDHF-like coronary vasodilation: Selective preservation in ischemia/reperfusion injury: Involvement of lipoxygenase products, VR1 receptors and C-fibers
    • McLean PG, Aston D, Sarkar D, and Ahluwalia A (2002) Protease-activated receptor-2 activation causes EDHF-like coronary vasodilation: selective preservation in ischemia/reperfusion injury: involvement of lipoxygenase products, VR1 receptors and C-fibers. Circ Res 90:465-472.
    • (2002) Circ Res , vol.90 , pp. 465-472
    • McLean, P.G.1    Aston, D.2    Sarkar, D.3    Ahluwalia, A.4
  • 20
    • 0037163104 scopus 로고    scopus 로고
    • Protease-activated receptor-2 stimulates angiogenesis and accelerates hemodynamic recovery in a mouse model of hindlimb ischemia
    • Milia AF, Salis MB, Stacca T, Pinna A, Madeddu P, Trevisani M, Geppetti P, and Emanueli C (2002) Protease-activated receptor-2 stimulates angiogenesis and accelerates hemodynamic recovery in a mouse model of hindlimb ischemia. Circ Res 91:346-352.
    • (2002) Circ Res , vol.91 , pp. 346-352
    • Milia, A.F.1    Salis, M.B.2    Stacca, T.3    Pinna, A.4    Madeddu, P.5    Trevisani, M.6    Geppetti, P.7    Emanueli, C.8
  • 21
    • 0030003829 scopus 로고    scopus 로고
    • The proteinase activated receptor-2 (PAR-2) mediates mitogenic responses in human vascular endothelial cells: Molecular characterization and evidence for functional coupling to the thrombin receptor
    • Mirza H, Yatsula V, and Bahou WF (1996) The proteinase activated receptor-2 (PAR-2) mediates mitogenic responses in human vascular endothelial cells: molecular characterization and evidence for functional coupling to the thrombin receptor. J Clin Investis 97:1705-1714.
    • (1996) J Clin Investis , vol.97 , pp. 1705-1714
    • Mirza, H.1    Yatsula, V.2    Bahou, W.F.3
  • 24
    • 0034608013 scopus 로고    scopus 로고
    • Thrombin responses in human endothelial cells, contributions from receptors other than PAR1 include the transactivation of PAR2 by thrombin-cleaved PAR1
    • O'Brien PJ, Prevost N, Molino M, Hollinger MK, Woolkalis MJ, Woulfe DS, and Brass LF (2000) Thrombin responses in human endothelial cells, contributions from receptors other than PAR1 include the transactivation of PAR2 by thrombin-cleaved PAR1. J Biol Chem 275:13502-13509.
    • (2000) J Biol Chem , vol.275 , pp. 13502-13509
    • O'Brien, P.J.1    Prevost, N.2    Molino, M.3    Hollinger, M.K.4    Woolkalis, M.J.5    Woulfe, D.S.6    Brass, L.F.7
  • 25
    • 1642279517 scopus 로고    scopus 로고
    • Protease-activated receptors: Contribution to physiology and disease
    • Ossovskaya VS and Bunnett NW (2004) Protease-activated receptors: contribution to physiology and disease. Physiol Rev 84:579-621.
    • (2004) Physiol Rev , vol.84 , pp. 579-621
    • Ossovskaya, V.S.1    Bunnett, N.W.2
  • 26
    • 0032539897 scopus 로고    scopus 로고
    • Stem cell factor in mast cells and increased mast cell density in idiopathic and ischemic cardiomyopathy
    • Patella V, Marino I, Arbustini E, Lamparter-Schummert B, Verga L, Adt M, and Marone G (1998) Stem cell factor in mast cells and increased mast cell density in idiopathic and ischemic cardiomyopathy. Circulation 97:971-978.
    • (1998) Circulation , vol.97 , pp. 971-978
    • Patella, V.1    Marino, I.2    Arbustini, E.3    Lamparter-Schummert, B.4    Verga, L.5    Adt, M.6    Marone, G.7
  • 27
    • 2442452711 scopus 로고    scopus 로고
    • Plasmin-mediated activation of platelets occurs by cleavage of protease-activated receptor 4
    • Quinton TM, Kim S, Derian CK, Jin J, and Kunapuli SP (2004) Plasmin-mediated activation of platelets occurs by cleavage of protease-activated receptor 4. J Biol Chem 279:18434-18439.
    • (2004) J Biol Chem , vol.279 , pp. 18434-18439
    • Quinton, T.M.1    Kim, S.2    Derian, C.K.3    Jin, J.4    Kunapuli, S.P.5
  • 28
    • 0030968521 scopus 로고    scopus 로고
    • Specific inhibition of thrombin-induced cell activation by the neutrophil proteinases elastase, cathepsin G and proteinase 3: Evidence for distinct cleavage sites within the aminoterminal domain of the thrombin receptor
    • Renesto P, Si-Tahar M, Moniatte M, Balloy V, van Dorsselaer A, Pidard D, and Chignard M (1997) Specific inhibition of thrombin-induced cell activation by the neutrophil proteinases elastase, cathepsin G and proteinase 3: evidence for distinct cleavage sites within the aminoterminal domain of the thrombin receptor. Blood 89:1944-1953.
    • (1997) Blood , vol.89 , pp. 1944-1953
    • Renesto, P.1    Si-Tahar, M.2    Moniatte, M.3    Balloy, V.4    Van Dorsselaer, A.5    Pidard, D.6    Chignard, M.7
  • 29
    • 0037465357 scopus 로고    scopus 로고
    • Protease-activated receptor 2-mediated vasodilatation in humans in vivo: Role of nitric oxide and prostanoids
    • Robin J, Kharbanda R, Mclean P, Campbell R, and Vallance P (2003) Protease-activated receptor 2-mediated vasodilatation in humans in vivo: role of nitric oxide and prostanoids. Circulation 107:954-959.
    • (2003) Circulation , vol.107 , pp. 954-959
    • Robin, J.1    Kharbanda, R.2    Mclean, P.3    Campbell, R.4    Vallance, P.5
  • 30
    • 0037764678 scopus 로고    scopus 로고
    • 2-adrenergic receptor signaling in ventricular myocytes: The role of Gi proteins and caveolae microdomains
    • 2-adrenergic receptor signaling in ventricular myocytes: the role of Gi proteins and caveolae microdomains. Mol Pharmacol 63:1338-1348.
    • (2003) Mol Pharmacol , vol.63 , pp. 1338-1348
    • Rybin, V.O.1    Pak, E.2    Alcott, S.3    Steinberg, S.F.4
  • 31
    • 0037592155 scopus 로고    scopus 로고
    • Neutrophil cathepsin G promotes detachment-induced cardiomyocyte apoptosis via a protease-activated receptor-independent mechanism
    • Sabri A, Alcott SG, Elouardighi H, Pak E, Derian C, Andrade-Gordon P, Kinnally K, and Steinberg SF (2003a) Neutrophil cathepsin G promotes detachment-induced cardiomyocyte apoptosis via a protease-activated receptor-independent mechanism. J Biol Chem 278:23944-23954.
    • (2003) J Biol Chem , vol.278 , pp. 23944-23954
    • Sabri, A.1    Alcott, S.G.2    Elouardighi, H.3    Pak, E.4    Derian, C.5    Andrade-Gordon, P.6    Kinnally, K.7    Steinberg, S.F.8
  • 32
    • 0037900130 scopus 로고    scopus 로고
    • Mechanisms of protease-activated receptor-4 actions in cardiomyocytes: Role of Src tyrosine kinase
    • Sabri A, Guo J, Elouardighi H, Darrow AL, Andrade-Gordon P, and Steinberg SF (2003b) Mechanisms of protease-activated receptor-4 actions in cardiomyocytes: role of Src tyrosine kinase. J Biol Chem 278:11714-11720.
    • (2003) J Biol Chem , vol.278 , pp. 11714-11720
    • Sabri, A.1    Guo, J.2    Elouardighi, H.3    Darrow, A.L.4    Andrade-Gordon, P.5    Steinberg, S.F.6
  • 33
    • 0034717192 scopus 로고    scopus 로고
    • Signaling properties and functions of two distinct cardiomyocyte protease-activated receptors
    • Sabri A, Muske G, Zhang H, Pak E, Darrow A, Andrade-Gordon P, and Steinberg SF (2000) Signaling properties and functions of two distinct cardiomyocyte protease-activated receptors. Circ Res 88:1054-1061.
    • (2000) Circ Res , vol.88 , pp. 1054-1061
    • Sabri, A.1    Muske, G.2    Zhang, H.3    Pak, E.4    Darrow, A.5    Andrade-Gordon, P.6    Steinberg, S.F.7
  • 34
    • 0037144657 scopus 로고    scopus 로고
    • Protease-activated receptor-1-mediated DNA synthesis in cardiac fibroblast is via epidermal growth factor receptor transactivation: Distinct PAR-1 signaling pathways in cardiac fibroblasts and cardiomyocytes
    • Sabri A, Short J, Guo J, and Steinberg SF (2002) Protease-activated receptor-1-mediated DNA synthesis in cardiac fibroblast is via epidermal growth factor receptor transactivation: distinct PAR-1 signaling pathways in cardiac fibroblasts and cardiomyocytes. Circ Res 91:532-539.
    • (2002) Circ Res , vol.91 , pp. 532-539
    • Sabri, A.1    Short, J.2    Guo, J.3    Steinberg, S.F.4
  • 36
    • 0025903807 scopus 로고
    • Thrombin modulates phosphoinositide metabolism, cytosolic calcium and impulse initiation in the heart
    • Steinberg SF, Robinson RB, Lieberman HB, Stern DM, and Rosen MR (1991) Thrombin modulates phosphoinositide metabolism, cytosolic calcium and impulse initiation in the heart. Circ Res 68:1216-1229.
    • (1991) Circ Res , vol.68 , pp. 1216-1229
    • Steinberg, S.F.1    Robinson, R.B.2    Lieberman, H.B.3    Stern, D.M.4    Rosen, M.R.5
  • 37
    • 0034055571 scopus 로고    scopus 로고
    • Review article: Proteinase-activated receptors - Novel signals for gastrointestinal pathophysiology
    • Vergnolle N (2000) Review article: proteinase-activated receptors - novel signals for gastrointestinal pathophysiology. Aliment Pharmacol Ther 14:257-266.
    • (2000) Aliment Pharmacol Ther , vol.14 , pp. 257-266
    • Vergnolle, N.1
  • 40
    • 0029797233 scopus 로고    scopus 로고
    • + exchanger: Evidence for a receptor-mediated mechanism involving protein kinase C
    • + exchanger: evidence for a receptor-mediated mechanism involving protein kinase C. Circ Res 79:705-715.
    • (1996) Circ Res , vol.79 , pp. 705-715
    • Yasutake, M.1    Haworth, R.S.2    King, A.3    Avkiran, M.4


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