Anti-cancer properties of glucosamine-hydrochloride in YD-8 human oral cancer cells: Induction of the caspase-dependent apoptosis and down-regulation of HIF-1α

Toxicology in Vitro

Volumn 26, Issue 1, 2012, Pages 42-50

  Jung, Chang Wook ^a   Jo, Jeong Rang ^b   Lee, Sang Han ^a   Park, Yu Kyoung ^b   Jung, Nak Kyun ^b   Song, Dae Kyu ^b   Bae, JaeHoon ^b   Nam, Ki Young ^b   Ha, Jung Sook ^b   Park, In Sook ^c   Park, Gy Young ^c   Jang, Byeong Churl ^b   Park, Jong Wook ^b  

^a Kyungpook National University   (South Korea)

^b Keimyung University   (South Korea)

^c Catholic University of Daegu   (South Korea)

Author keywords

Caspases; ER stress; Glucosamine HCl; HIF 1 ; Mcl 1; YD 8 cells

Indexed keywords

ALPHA TOCOPHEROL; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CYTOCHROME C; GLUCOSAMINE; GLUCOSE REGULATED PROTEIN 78; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROTEIN MCL 1; REACTIVE OXYGEN METABOLITE;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER INHIBITION; CELL ASSAY; CELL PROLIFERATION; CELL STRAIN YD 10B; CELL STRAIN YD 38; CELL STRAIN YD 8; CONTROLLED STUDY; CYTOSOL; DNA FRAGMENTATION; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MITOCHONDRION; MOUTH CANCER; REGULATORY MECHANISM; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CARCINOMA, SQUAMOUS CELL; CASPASE 3; CELL LINE, TUMOR; CELL PROLIFERATION; CYTOCHROMES C; DNA FRAGMENTATION; DOWN-REGULATION; GLUCOSAMINE; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MOUTH NEOPLASMS; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84855359639     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2011.10.005     Document Type: Article

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