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Volumn , Issue , 2011, Pages

Neuroprotective mechanisms of PPARδ: Modulation of oxidative stress and inflammatory processes

Author keywords

[No Author keywords available]

Indexed keywords

2 [4 [2 [3 CYCLOHEXYL 1 (4 CYCLOHEXYLBUTYL)UREIDO]ETHYL]PHENYLTHIO] 2 METHYLPROPIONIC ACID; 4 [4 [3 (4 ACETYL 3 HYDROXY 2 PROPYLPHENOXY)PROPOXY]PHENOXY]ACETIC ACID; [2 METHYL 4 [4 METHYL 2 (4 TRIFLUOROMETHYLPHENYL) 5 THIAZOLYLMETHYLTHIO]PHENOXY]ACETIC ACID; [4 [2 (3 FLUORO 4 TRIFLUOROMETHYLPHENYL) 4 METHYL 5 THIAZOLYLMETHYLTHIO] 2 METHYLPHENOXY]ACETIC ACID; CYTOKINE; FENOFIBRATE; L 160043; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA AGONIST; PIOGLITAZONE; UNCLASSIFIED DRUG;

EID: 84855281838     PISSN: 16874757     EISSN: 16874765     Source Type: Journal    
DOI: 10.1155/2011/373560     Document Type: Review
Times cited : (57)

References (90)
  • 1
    • 0033574663 scopus 로고    scopus 로고
    • A unified nomenclature system for the nuclear receptor superfamily
    • Nuclear Receptors Nomenclature Committee
    • Nuclear Receptors Nomenclature Committee, A unified nomenclature system for the nuclear receptor superfamily Cell 1999 97 2 161 163
    • (1999) Cell , vol.97 , Issue.2 , pp. 161-163
  • 2
    • 0029731662 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: A nuclear receptor signaling pathway in lipid physiology
    • DOI 10.1146/annurev.cellbio.12.1.335
    • Lemberger T., Desvergne B., Wahli W., Peroxisome proliferator-activated receptors: a nuclear receptor signaling pathway in lipid physiology Annual Review of Cell and Developmental Biology 1996 12 335 363 (Pubitemid 26422717)
    • (1996) Annual Review of Cell and Developmental Biology , vol.12 , pp. 335-363
    • Lemberger, T.1    Desvergne, B.2    Wahli, W.3
  • 3
    • 0041887308 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: Regulation of transcriptional activities and roles in inflammation
    • DOI 10.1016/S0960-0760(03)00214-0
    • Blanquart C., Barbier O., Fruchart J. C., Staels B., Glineur C., Peroxisome proliferator-activated receptors: regulation of transcriptional activities and roles in inflammation Journal of Steroid Biochemistry and Molecular Biology 2003 85 25 267 273 (Pubitemid 37011102)
    • (2003) Journal of Steroid Biochemistry and Molecular Biology , vol.85 , Issue.2-5 , pp. 267-273
    • Blanquart, C.1    Barbier, O.2    Fruchart, J.C.3    Staels, B.4    Glineur, C.5
  • 4
    • 0025726848 scopus 로고
    • Two cis-acting regulatory sequences in the peroxisome proliferator-responsive enhancer region of rat acyl-CoA oxidase gene
    • Osumi T., Wen J. K., Hashimoto T., Two cis-acting regulatory sequences in the peroxisome proliferator-responsive enhancer region of rat acyl-CoA oxidase gene Biochemical and Biophysical Research Communications 1991 175 3 866 871
    • (1991) Biochemical and Biophysical Research Communications , vol.175 , Issue.3 , pp. 866-871
    • Osumi, T.1    Wen, J.K.2    Hashimoto, T.3
  • 5
    • 77957933413 scopus 로고    scopus 로고
    • Molecular mechanisms and genome-wide aspects of PPAR subtype specific transactivation
    • Bugge A., Mandrup S., Molecular mechanisms and genome-wide aspects of PPAR subtype specific transactivation PPAR Research 2010 2010 12
    • (2010) PPAR Research , vol.2010 , pp. 12
    • Bugge, A.1    Mandrup, S.2
  • 7
    • 77950363010 scopus 로고    scopus 로고
    • Mechanisms underlying inflammation in neurodegeneration
    • Glass C. K., Saijo K., Winner B., Marchetto M. C., Gage F. H., Mechanisms underlying inflammation in neurodegeneration Cell 2010 140 6 918 934
    • (2010) Cell , vol.140 , Issue.6 , pp. 918-934
    • Glass, C.K.1    Saijo, K.2    Winner, B.3    Marchetto, M.C.4    Gage, F.H.5
  • 8
    • 38449085356 scopus 로고    scopus 로고
    • Mechanisms of anti-inflammatory and neuroprotective actions of PPAR-gamma agonists
    • DOI 10.2741/2802
    • Kapadia R., Yi J. H., Vemuganti R., Mechanisms of anti-inflammatory and neuroprotective actions of PPAR-gamma agonists Frontiers in Bioscience 2008 13 5 1813 1826 (Pubitemid 351599735)
    • (2008) Frontiers in Bioscience , vol.13 , Issue.5 , pp. 1813-1826
    • Kapadia, R.1    Yi, J.-H.2    Vemuganti, R.3
  • 9
    • 34548494847 scopus 로고    scopus 로고
    • Drug Insight: Effects mediated by peroxisome proliferator-activated receptor-γ in CNS disorders
    • DOI 10.1038/ncpneuro0586, PII NCPNEURO0586
    • Heneka M. T., Landreth G. E., Hll M., Drug insight: effects mediated by peroxisome proliferator-activated receptor-gamma in CNS disorders Nature Clinical Practice Neurology 2007 3 9 496 504 (Pubitemid 47377609)
    • (2007) Nature Clinical Practice Neurology , vol.3 , Issue.9 , pp. 496-504
    • Heneka, M.T.1    Landreth, G.E.2    Hull, M.3
  • 11
    • 0345118108 scopus 로고    scopus 로고
    • Immunolocalization of peroxisome proliferator-activated receptors and retinoid X receptors in the adult rat CNS
    • DOI 10.1016/j.neuroscience.2003.08.064
    • Moreno S., Farioli-vecchioli S., Cer M. P., Immunolocalization of peroxisome proliferator-activated receptors and retinoid X receptors in the adult rat CNS Neuroscience 2004 123 1 131 145 (Pubitemid 37518482)
    • (2004) Neuroscience , vol.123 , Issue.1 , pp. 131-145
    • Moreno, S.1    Farioli-vecchioli, S.2    Ceru, M.P.3
  • 15
    • 33748755428 scopus 로고    scopus 로고
    • Therapeutic rescue of neurodegeneration in experimental type 3 diabetes: Relevance to Alzheimer's disease
    • de la Monte S. M., Tong M., Lester-Coll N., Plater M. Jr., Wands J. R., Therapeutic rescue of neurodegeneration in experimental type 3 diabetes: relevance to Alzheimer's disease Journal of Alzheimer's Disease 2006 10 1 89 109 (Pubitemid 44401370)
    • (2006) Journal of Alzheimer's Disease , vol.10 , Issue.1 , pp. 89-109
    • De La Monte, S.M.1    Tong, M.2    Lester-Coll, N.3    Plater Jr., M.4    Wands, J.R.5
  • 16
    • 77955017449 scopus 로고    scopus 로고
    • Impairment of PGC-1alpha expression, neuropathology and hepatic steatosis in a transgenic mouse model of Huntington's disease following chronic energy deprivation
    • Chaturvedi R. K., Calingasan N. Y., Yang L., Hennessey T., Johri A., Beal M. F., Impairment of PGC-1alpha expression, neuropathology and hepatic steatosis in a transgenic mouse model of Huntington's disease following chronic energy deprivation Human Molecular Genetics 2010 19 16 3190 3205
    • (2010) Human Molecular Genetics , vol.19 , Issue.16 , pp. 3190-3205
    • Chaturvedi, R.K.1    Calingasan, N.Y.2    Yang, L.3    Hennessey, T.4    Johri, A.5    Beal, M.F.6
  • 19
    • 79851512548 scopus 로고    scopus 로고
    • PPAR deficient mice develop elevated Th1/Th17 responses and prolonged experimental autoimmune encephalomyelitis
    • Kanakasabai S., Walline C. C., Chakraborty S., Bright J. J., PPAR deficient mice develop elevated Th1/Th17 responses and prolonged experimental autoimmune encephalomyelitis Brain Research 2011 1376 101 112
    • (2011) Brain Research , vol.1376 , pp. 101-112
    • Kanakasabai, S.1    Walline, C.C.2    Chakraborty, S.3    Bright, J.J.4
  • 21
    • 36249022189 scopus 로고    scopus 로고
    • Neuroprotective actions of noradrenaline: Effects on glutathione synthesis and activation of peroxisome proliferator activated receptor delta
    • DOI 10.1111/j.1471-4159.2007.04888.x
    • Madrigal J. L. M., Kalinin S., Richardson J. C., Feinstein D. L., Neuroprotective actions of noradrenaline: effects on glutathione synthesis and activation of peroxisome proliferator activated receptor delta Journal of Neurochemistry 2007 103 5 2092 2101 (Pubitemid 350126619)
    • (2007) Journal of Neurochemistry , vol.103 , Issue.5 , pp. 2092-2101
    • Madrigal, J.L.M.1    Kalinin, S.2    Richardson, J.C.3    Feinstein, D.L.4
  • 22
    • 70249113348 scopus 로고    scopus 로고
    • A PPARdelta agonist reduces amyloid burden and brain inflammation in a transgenic mouse model of Alzheimer's disease
    • Kalinin S., Richardson J. C., Feinstein D. L., A PPARdelta agonist reduces amyloid burden and brain inflammation in a transgenic mouse model of Alzheimer's disease Current Alzheimer Research 2009 6 5 431 437
    • (2009) Current Alzheimer Research , vol.6 , Issue.5 , pp. 431-437
    • Kalinin, S.1    Richardson, J.C.2    Feinstein, D.L.3
  • 24
    • 35348908406 scopus 로고    scopus 로고
    • Systematic Gene Expression Mapping Clusters Nuclear Receptors According to Their Function in the Brain
    • DOI 10.1016/j.cell.2007.09.012, PII S0092867407011968
    • Gofflot F., Chartoire N., Vasseur L., Heikkinen S., Dembele D., Le Merrer J., Auwerx J., Systematic gene expression mapping clusters nuclear receptors according to their function in the brain Cell 2007 131 2 405 418 (Pubitemid 47576140)
    • (2007) Cell , vol.131 , Issue.2 , pp. 405-418
    • Gofflot, F.1    Chartoire, N.2    Vasseur, L.3    Heikkinen, S.4    Dembele, D.5    Le Merrer, J.6    Auwerx, J.7
  • 26
    • 0037728848 scopus 로고    scopus 로고
    • Localization of PPARδ in murine central nervous system: Expression in oligodendrocytes and neurons
    • DOI 10.1016/S0006-8993(03)02515-0
    • Woods J. W., Tanen M., Figueroa D. J., Biswas C., Zycband E., Moller D. E., Austin C. P., Berger J. P., Localization of PPAR in murine central nervous system: expression in oligodendrocytes and neurons Brain Research 2003 975 1-2 10 21 (Pubitemid 36588548)
    • (2003) Brain Research , vol.975 , Issue.1-2 , pp. 10-21
    • Woods, J.W.1    Tanen, M.2    Figueroa, D.J.3    Biswas, C.4    Zycband, E.5    Moller, D.E.6    Austin, C.P.7    Berger, J.P.8
  • 27
    • 0031788318 scopus 로고    scopus 로고
    • Differential expression of peroxisome proliferator-activated receptor- α, -β, and -γ during rat embryonic development
    • DOI 10.1210/en.139.6.2748
    • Braissant O., Wahli W., Differential expression of peroxisome proliferator-activated receptor-,-, and- during rat embryonic development Endocrinology 1998 139 6 2748 2754 (Pubitemid 28512383)
    • (1998) Endocrinology , vol.139 , Issue.6 , pp. 2748-2754
    • Braissant, O.1    Wahli, W.2
  • 29
    • 38349098471 scopus 로고    scopus 로고
    • Expression of nuclear receptor mRNA and liver X receptor-mediated regulation of ABC transporter A1 at rat blood-brain barrier
    • Akanuma S. I., Hori S., Ohtsuki S., Fujiyoshi M., Terasaki T., Expression of nuclear receptor mRNA and liver X receptor-mediated regulation of ABC transporter A1 at rat blood-brain barrier Neurochemistry International 2008 52 4-5 669 674
    • (2008) Neurochemistry International , vol.52 , Issue.45 , pp. 669-674
    • Akanuma, S.I.1    Hori, S.2    Ohtsuki, S.3    Fujiyoshi, M.4    Terasaki, T.5
  • 30
    • 13844308524 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPARs) and related transcription factors in differentiating astrocyte cultures
    • DOI 10.1016/j.neuroscience.2004.11.008
    • Cristiano L., Cimini A., Moreno S., Ragnelli A. M., Paola Cer M., Peroxisome proliferator-activated receptors (PPARs) and related transcription factors in differentiating astrocyte cultures Neuroscience 2005 131 3 577 587 (Pubitemid 40261214)
    • (2005) Neuroscience , vol.131 , Issue.3 , pp. 577-587
    • Cristiano, L.1    Cimini, A.2    Moreno, S.3    Ragnelli, A.M.4    Ceru, M.P.5
  • 31
    • 0035427881 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPARs) and peroxisomes in rat cortical and cerebellar astrocytes
    • Cristiano L., Bernardo A., Cer M. P., Peroxisome proliferator-activated receptors (PPARs) and peroxisomes in rat cortical and cerebellar astrocytes Journal of Neurocytology 2001 30 8 671 683
    • (2001) Journal of Neurocytology , vol.30 , Issue.8 , pp. 671-683
    • Cristiano, L.1    Bernardo, A.2    Cer, M.P.3
  • 33
    • 27944505915 scopus 로고    scopus 로고
    • PPARs in diseases: Control mechanisms of inflammation
    • DOI 10.2174/092986705774462905
    • Kostadinova R., Wahli W., Michalik L., PPARs in diseases: control mechanisms of inflammation Current Medicinal Chemistry 2005 12 25 2995 3009 (Pubitemid 41672488)
    • (2005) Current Medicinal Chemistry , vol.12 , Issue.25 , pp. 2995-3009
    • Kostadinova, R.1    Wahli, W.2    Michalik, L.3
  • 34
    • 70349111436 scopus 로고    scopus 로고
    • Emerging roles of peroxisome proliferator-activated receptor- / in inflammation
    • Bishop-Bailey D., Bystrom J., Emerging roles of peroxisome proliferator-activated receptor- / in inflammation Pharmacology and Therapeutics 2009 124 2 141 150
    • (2009) Pharmacology and Therapeutics , vol.124 , Issue.2 , pp. 141-150
    • Bishop-Bailey, D.1    Bystrom, J.2
  • 35
    • 78651298914 scopus 로고    scopus 로고
    • PPAR activation has dichotomous control on the expression levels of cytosolic and secretory phospholipase A2 in astrocytes; Inhibition in nave, untreated cells and enhancement in LPS-stimulated cells
    • Sergeeva M. G., Aleshin S. E., Grabeklis S., Reiser G., PPAR activation has dichotomous control on the expression levels of cytosolic and secretory phospholipase A2 in astrocytes; inhibition in nave, untreated cells and enhancement in LPS-stimulated cells Journal of Neurochemistry 2010 115 2 399 410
    • (2010) Journal of Neurochemistry , vol.115 , Issue.2 , pp. 399-410
    • Sergeeva, M.G.1    Aleshin, S.E.2    Grabeklis, S.3    Reiser, G.4
  • 36
    • 30744460411 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor δ (PPARδ) activation protects H9c2 cardiomyoblasts from oxidative stress-induced apoptosis
    • DOI 10.1016/j.cardiores.2005.10.019, PII S000863630500492X
    • Pesant M., Sueur S., Dutartre P., Tallandier M., Grimaldi P. A., Rochette L., Connat J. L., Peroxisome proliferator-activated receptor (PPAR ) activation protects H9c2 cardiomyoblasts from oxidative stress-induced apoptosis Cardiovascular Research 2006 69 2 440 449 (Pubitemid 43098800)
    • (2006) Cardiovascular Research , vol.69 , Issue.2 , pp. 440-449
    • Pesant, M.1    Sueur, S.2    Dutartre, P.3    Tallandier, M.4    Grimaldi, P.A.5    Rochette, L.6    Connat, J.-L.7
  • 37
    • 0036908619 scopus 로고    scopus 로고
    • Identification of a functional peroxisome proliferator-activated receptor response element in the rat catalase promoter
    • DOI 10.1210/me.2002-0020
    • Girnun G. D., Domann F. E., Moore S. A., Robbins M. E. C., Identification of a functional peroxisome proliferator-activated receptor response element in the rat catalase promoter Molecular Endocrinology 2002 16 12 2793 2801 (Pubitemid 36020658)
    • (2002) Molecular Endocrinology , vol.16 , Issue.12 , pp. 2793-2801
    • Girnun, G.D.1    Domann, F.E.2    Moore, S.A.3    Robbins, M.E.C.4
  • 38
    • 13844256366 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor β/δ activation inhibits hypertrophy in neonatal rat cardiomyocytes
    • DOI 10.1016/j.cardiores.2004.11.011
    • Planavila A., Rodrguez-Calvo R., Jové M., Michalik L., Wahli W., Laguna J. C., Vzquez-Carrera M., Peroxisome proliferator-activated receptor / activation inhibits hypertrophy in neonatal rat cardiomyocytes Cardiovascular Research 2005 65 4 832 841 (Pubitemid 40249728)
    • (2005) Cardiovascular Research , vol.65 , Issue.4 , pp. 832-841
    • Planavila, A.1    Rodriguez-Calvo, R.2    Jove, M.3    Michalik, L.4    Wahli, W.5    Laguna, J.C.6    Vazquez-Carrera, M.7
  • 40
    • 0142116239 scopus 로고    scopus 로고
    • Transcriptional Repression of Atherogenic Inflammation: Modulation by PPARδ
    • DOI 10.1126/science.1087344
    • Lee C. H., Chawla A., Urbiztondo N., Liao D., Boisvert W. A., Evans R. M., Curtiss L. K., Transcriptional repression of atherogenic inflammation: modulation by PPAR Science 2003 302 5644 453 457 (Pubitemid 37296272)
    • (2003) Science , vol.302 , Issue.5644 , pp. 453-457
    • Lee, C.-H.1    Chawla, A.2    Urbiztondo, N.3    Liao, D.4    Boisvert, W.A.5    Evans, R.M.6
  • 42
    • 77954383974 scopus 로고    scopus 로고
    • Peroxisome-proliferator-activated receptors and peroxisome-proliferator- activated receptors / and the regulation of interleukin 1 receptor antagonist expression by pioglitazone in ischaemic brain
    • Glatz T., Stck I., Nguyen-Ngoc M., Gohlke P., Herdegen T., Culman J., Zhao Y., Peroxisome-proliferator-activated receptors and peroxisome- proliferator-activated receptors / and the regulation of interleukin 1 receptor antagonist expression by pioglitazone in ischaemic brain Journal of Hypertension 2010 28 7 1488 1497
    • (2010) Journal of Hypertension , vol.28 , Issue.7 , pp. 1488-1497
    • Glatz, T.1    Stck, I.2    Nguyen-Ngoc, M.3    Gohlke, P.4    Herdegen, T.5    Culman, J.6    Zhao, Y.7
  • 43
    • 77951793925 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor regulation of miR-15a in ischemia-induced cerebral vascular endothelial injury
    • Yin K. J., Deng Z., Hamblin M., Xiang Y., Huang H., Zhang J., Jiang X., Wang Y., Chen Y. E., Peroxisome proliferator-activated receptor regulation of miR-15a in ischemia-induced cerebral vascular endothelial injury Journal of Neuroscience 2010 30 18 6398 6408
    • (2010) Journal of Neuroscience , vol.30 , Issue.18 , pp. 6398-6408
    • Yin, K.J.1    Deng, Z.2    Hamblin, M.3    Xiang, Y.4    Huang, H.5    Zhang, J.6    Jiang, X.7    Wang, Y.8    Chen, Y.E.9
  • 44
    • 3042755613 scopus 로고    scopus 로고
    • Effect of the peroxisome proliferator-activated receptor activator GW0742 in rat cultured cerebellar granule neurons
    • Basu-Modak S., Braissant O., Escher P., Effect of the peroxisome proliferator-activated receptor activator GW0742 in rat cultured cerebellar granule neurons Journal of Neuroscience Research 2004 77 2 240 249
    • (2004) Journal of Neuroscience Research , vol.77 , Issue.2 , pp. 240-249
    • Basu-Modak, S.1    Braissant, O.2    Escher, P.3
  • 45
    • 0031025835 scopus 로고    scopus 로고
    • Autoimmune pathogenesis of multiple sclerosis: Role of autoreactive T lymphocytes and new immunotherapeutic strategies
    • Stinissen P., Raus J., Zhang J., Autoimmune pathogenesis of multiple sclerosis: role of autoreactive T lymphocytes and new immunotherapeutic strategies Critical Reviews in Immunology 1997 17 1 33 75 (Pubitemid 27068807)
    • (1997) Critical Reviews in Immunology , vol.17 , Issue.1 , pp. 33-75
    • Stinissen, P.1    Raus, J.2    Zhang, J.3
  • 46
    • 0030970058 scopus 로고    scopus 로고
    • Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis
    • DOI 10.1007/s001090050101
    • Benveniste E. N., Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis Journal of Molecular Medicine 1997 75 3 165 173 (Pubitemid 27132679)
    • (1997) Journal of Molecular Medicine , vol.75 , Issue.3 , pp. 165-173
    • Benveniste, E.N.1
  • 47
    • 0029058504 scopus 로고
    • Myelin oligodendrocyte glycoprotein induces a demyelinating encephalomyelitis resembling multiple sclerosis
    • Johns T. G., Kerlero de Rosbo N., Menon K. K., Abo S., Gonzales M. F., Bernard C. C. A., Myelin oligodendrocyte glycoprotein induces a demyelinating encephalomyelitis resembling multiple sclerosis Journal of Immunology 1995 154 10 5536 5541
    • (1995) Journal of Immunology , vol.154 , Issue.10 , pp. 5536-5541
    • Johns, T.G.1    Kerlero De Rosbo, N.2    Menon, K.K.3    Abo, S.4    Gonzales, M.F.5    Bernard, C.C.A.6
  • 49
    • 0037207510 scopus 로고    scopus 로고
    • TNFα downregulates PPARδ expression in oligodendrocyte progenitor cells: Implications for demyelinating diseases
    • DOI 10.1002/glia.10143
    • Cimini A., Bernardo A., Cifone M. G., Di Muzio L., Di Loreto S., TNF downregulates PPAR expression in oligodendrocyte progenitor cells: implications for demyelinating diseases GLIA 2003 41 1 3 14 (Pubitemid 36164280)
    • (2003) GLIA , vol.41 , Issue.1 , pp. 3-14
    • Cimini, A.1    Bernardo, A.2    Cifone, G.3    Di Muzio, L.4    Di Loreto, S.5
  • 50
    • 77954496807 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor agonists inhibit T helper type 1 (Th1) and Th17 responses in experimental allergic encephalomyelitis
    • Kanakasabai S., Chearwae W., Walline C. C., Iams W., Adams S. M., Bright J. J., Peroxisome proliferator-activated receptor agonists inhibit T helper type 1 (Th1) and Th17 responses in experimental allergic encephalomyelitis Immunology 2010 130 4 572 588
    • (2010) Immunology , vol.130 , Issue.4 , pp. 572-588
    • Kanakasabai, S.1    Chearwae, W.2    Walline, C.C.3    Iams, W.4    Adams, S.M.5    Bright, J.J.6
  • 51
    • 77952571744 scopus 로고    scopus 로고
    • Genetic ablation of steroid receptor coactivator-3 promotes PPAR- -mediated alternative activation of microglia in experimental autoimmune encephalomyelitis
    • Xiao Y., Xu J., Wang S., Mao C., Jin M., Ning G., Xu J., Zhang Y., Genetic ablation of steroid receptor coactivator-3 promotes PPAR- -mediated alternative activation of microglia in experimental autoimmune encephalomyelitis GLIA 2010 58 8 932 942
    • (2010) GLIA , vol.58 , Issue.8 , pp. 932-942
    • Xiao, Y.1    Xu, J.2    Wang, S.3    Mao, C.4    Jin, M.5    Ning, G.6    Xu, J.7    Zhang, Y.8
  • 52
    • 44349112305 scopus 로고    scopus 로고
    • Adipocyte-Derived Th2 Cytokines and Myeloid PPARδ Regulate Macrophage Polarization and Insulin Sensitivity
    • DOI 10.1016/j.cmet.2008.04.002, PII S1550413108001125
    • Kang K., Reilly S. M., Karabacak V., Gangl M. R., Fitzgerald K., Hatano B., Lee C. H., Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity Cell Metabolism 2008 7 6 485 495 (Pubitemid 351729204)
    • (2008) Cell Metabolism , vol.7 , Issue.6 , pp. 485-495
    • Kang, K.1    Reilly, S.M.2    Karabacak, V.3    Gangl, M.R.4    Fitzgerald, K.5    Hatano, B.6    Lee, C.-H.7
  • 54
    • 66449124004 scopus 로고    scopus 로고
    • Effects of the PPAR- agonist GW501516 in an in vitro model of brain inflammation and antibody-induced demyelination
    • Defaux A., Zurich M. G., Braissant O., Honegger P., Monnet-Tschudi F., Effects of the PPAR- agonist GW501516 in an in vitro model of brain inflammation and antibody-induced demyelination Journal of Neuroinflammation 2009 6, article 15
    • (2009) Journal of Neuroinflammation , vol.615
    • Defaux, A.1    Zurich, M.G.2    Braissant, O.3    Honegger, P.4    Monnet-Tschudi, F.5
  • 55
    • 0019872434 scopus 로고
    • Selective loss of neurones of origin of adrenergic projection to cerebral cortex (nucleus locus coeruleus) in senile dementia
    • Bondareff W., Mountjoy C. Q., Roth M., Selective loss of neurones of origin of adrenergic projection to cerebral cortex (nucleus locus coeruleus) in senile dementia The Lancet 1981 1 8223 783 784
    • (1981) The Lancet , vol.1 , Issue.8223 , pp. 783-784
    • Bondareff, W.1    Mountjoy, C.Q.2    Roth, M.3
  • 56
    • 0029792928 scopus 로고    scopus 로고
    • New clues to Alzheimer's disease: Unraveling the roles of amyloid and tau
    • DOI 10.1038/nm0896-850
    • Yankner B. A., New clues to Alzheimer's disease: unraveling the roles of amyloid and tau Nature Medicine 1996 2 8 850 852 (Pubitemid 26296747)
    • (1996) Nature Medicine , vol.2 , Issue.8 , pp. 850-852
    • Yankner, B.A.1
  • 58
    • 0033605607 scopus 로고    scopus 로고
    • Insulin-degrading enzyme in the Alzheimer's disease brain: Prominent localization in neurons and senile plaques
    • DOI 10.1016/S0304-3940(99)00135-4, PII S0304394099001354
    • Bernstein H. G., Ansorge S., Riederer P., Reiser M., Frlich L., Bogerts B., Insulin-degrading enzyme in the Alzheimer's disease brain: prominent localization in neurons and senile plaques Neuroscience Letters 1999 263 2-3 161 164 (Pubitemid 29158953)
    • (1999) Neuroscience Letters , vol.263 , Issue.2-3 , pp. 161-164
    • Bernstein, H.-G.1    Ansorge, S.2    Riederer, P.3    Reiser, M.4    Frolich, L.5    Bogerts, B.6
  • 59
    • 0032902974 scopus 로고    scopus 로고
    • Oxidative alterations in Alzheimer's disease
    • Markesbery W. R., Carney J. M., Oxidative alterations in Alzheimer's disease Brain Pathology 1999 9 1 133 146 (Pubitemid 29056524)
    • (1999) Brain Pathology , vol.9 , Issue.1 , pp. 133-146
    • Markesbery, W.R.1    Carney, J.M.2
  • 60
    • 0030989545 scopus 로고    scopus 로고
    • 4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease
    • Sayre L. M., Zelasko D. A., Harris P. L. R., Perry G., Salomon R. G., Smith M. A., 4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease Journal of Neurochemistry 1999 68 5 2092 2097
    • (1999) Journal of Neurochemistry , vol.68 , Issue.5 , pp. 2092-2097
    • Sayre, L.M.1    Zelasko, D.A.2    Harris, P.L.R.3    Perry, G.4    Salomon, R.G.5    Smith, M.A.6
  • 61
    • 18144406539 scopus 로고    scopus 로고
    • Oxidative stress and inflammation in Parkinson's disease: Is there a causal link?
    • DOI 10.1016/j.expneurol.2005.01.013
    • Hald A., Lotharius J., Oxidative stress and inflammation in Parkinson's disease: is there a causal link? Experimental Neurology 2005 193 2 279 290 (Pubitemid 40616179)
    • (2005) Experimental Neurology , vol.193 , Issue.2 , pp. 279-290
    • Hald, A.1    Lotharius, J.2
  • 62
    • 0347087323 scopus 로고    scopus 로고
    • Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with IκBα induction and block of NFκB and iNOS activation
    • Dehmer T., Heneka M. T., Sastre M., Dichgans J., Schulz J. B., Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation Journal of Neurochemistry 2004 88 2 494 501 (Pubitemid 38084565)
    • (2004) Journal of Neurochemistry , vol.88 , Issue.2 , pp. 494-501
    • Dehmer, T.1    Heneka, M.T.2    Sastre, M.3    Dichgans, J.4    Schulz, J.B.5
  • 63
    • 1842714301 scopus 로고    scopus 로고
    • Neuroinflammation, COX-2, and ALS - A dual role?
    • DOI 10.1016/j.expneurol.2003.12.009, PII S001448860400007X
    • Consilvio C., Vincent A. M., Feldman E. L., Neuroinflammation, COX-2, and ALS-A dual role? Experimental Neurology 2004 187 1 1 10 (Pubitemid 38470006)
    • (2004) Experimental Neurology , vol.187 , Issue.1 , pp. 1-10
    • Consilvio, C.1    Vincent, A.M.2    Feldman, E.L.3
  • 64
    • 34548214548 scopus 로고    scopus 로고
    • 2
    • DOI 10.1111/j.1471-4159.2007.04663.x
    • Strokin M., Sergeeva M., Reiser G., Prostaglandin synthesis in rat brain astrocytes is under the control of the n-3 docosahexaenoic acid, released by group VIB calcium-independent phospholipase A2 Journal of Neurochemistry 2007 102 6 1771 1782 (Pubitemid 47329261)
    • (2007) Journal of Neurochemistry , vol.102 , Issue.6 , pp. 1771-1782
    • Strokin, M.1    Sergeeva, M.2    Reiser, G.3
  • 65
    • 33846452220 scopus 로고    scopus 로고
    • Phospholipase A2 in the central nervous system: Implications for neurodegenerative diseases
    • Forlenza O. V., Schaeffer E. L., Gattaz W. F., Phospholipase A2 in the central nervous system: implications for neurodegenerative diseases Journal of Neural Transmission 2007 114 2 231 238
    • (2007) Journal of Neural Transmission , vol.114 , Issue.2 , pp. 231-238
    • Forlenza, O.V.1    Schaeffer, E.L.2    Gattaz, W.F.3
  • 66
    • 32944466122 scopus 로고    scopus 로고
    • Is there a future for cyclo-oxygenase inhibitors in Alzheimer's disease?
    • DOI 10.2165/00023210-200620020-00001
    • Ho L., Qin W., Stetka B. S., Pasinetti G. M., Is there a future for cyclo-oxygenase inhibitors in Alzheimer's disease? CNS Drugs 2006 20 2 85 98 (Pubitemid 43261694)
    • (2006) CNS Drugs , vol.20 , Issue.2 , pp. 85-98
    • Ho, L.1    Qin, W.2    Stetka, B.S.3    Pasinetti, G.M.4
  • 67
    • 67650792427 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor (PPAR)- positively controls and PPAR negatively controls cyclooxygenase-2 expression in rat brain astrocytes through a convergence on PPAR / via mutual control of PPAR expression levels
    • Aleshin S., Grabeklis S., Hanck T., Sergeeva M., Reiser G., Peroxisome proliferator-activated receptor (PPAR)- positively controls and PPAR negatively controls cyclooxygenase-2 expression in rat brain astrocytes through a convergence on PPAR / via mutual control of PPAR expression levels Molecular Pharmacology 2009 76 2 414 424
    • (2009) Molecular Pharmacology , vol.76 , Issue.2 , pp. 414-424
    • Aleshin, S.1    Grabeklis, S.2    Hanck, T.3    Sergeeva, M.4    Reiser, G.5
  • 68
    • 33644850757 scopus 로고    scopus 로고
    • Whole-brain radiotherapy in the management of brain metastasis
    • DOI 10.1200/JCO.2005.04.6185
    • Khuntia D., Brown P., Li J., Mehta M. P., Whole-brain radiotherapy in the management of brain metastasis Journal of Clinical Oncology 2006 24 8 1295 1304 (Pubitemid 46622033)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.8 , pp. 1295-1304
    • Khuntia, D.1    Brown, P.2    Li, J.3    Mehta, M.P.4
  • 69
    • 0028695963 scopus 로고
    • Cognitive impairment and quality of life in long-term survivors of malignant brain tumors
    • Giovagnoli A. R., Boiardi A., Cognitive impairment and quality of life in long-term survivors of malignant brain tumors The Italian Journal of Neurological Sciences 1994 15 9 481 488
    • (1994) The Italian Journal of Neurological Sciences , vol.15 , Issue.9 , pp. 481-488
    • Giovagnoli, A.R.1    Boiardi, A.2
  • 70
    • 0036735783 scopus 로고    scopus 로고
    • Irradiation induces neural precursor-cell dysfunction
    • DOI 10.1038/nm749
    • Monje M. L., Mizumatsu S., Fike J. R., Palmer T. D., Irradiation induces neural precursor-cell dysfunction Nature Medicine 2002 8 9 955 962 (Pubitemid 35033699)
    • (2002) Nature Medicine , vol.8 , Issue.9 , pp. 955-962
    • Monje, M.L.1    Mizumatsu, S.2    Fike, J.R.3    Palmer, T.D.4
  • 73
    • 5444256254 scopus 로고    scopus 로고
    • Microglia
    • DOI 10.1023/B:MEBR.0000043984.73063.d8
    • van Rossum D., Hanisch U. K., Microglia Metabolic Brain Disease 2004 19 3-4 393 411 (Pubitemid 39361196)
    • (2004) Metabolic Brain Disease , vol.19 , Issue.3-4 , pp. 393-411
    • Van Rossum, D.1    Hanisch, U.-K.2
  • 74
    • 0035399785 scopus 로고    scopus 로고
    • Microglia in neurodegeneration: Molecular aspects
    • DOI 10.1002/jemt.1120
    • Gebicke-Haerter P. J., Microglia in neurodegeneration: molecular aspects Microscopy Research and Technique 2001 54 1 47 58 (Pubitemid 32537334)
    • (2001) Microscopy Research and Technique , vol.54 , Issue.1 , pp. 47-58
    • Gebicke-Haerter, P.J.1
  • 75
    • 0032937860 scopus 로고    scopus 로고
    • The role of microglia and macrophages in the pathophysiology of the CNS
    • DOI 10.1016/S0301-0082(98)00083-5, PII S0301008298000835
    • Stollg G., Jander S., The role of microglia and macrophages in the pathophysiology of the CNS Progress in Neurobiology 1999 58 3 233 247 (Pubitemid 29193056)
    • (1999) Progress in Neurobiology , vol.58 , Issue.3 , pp. 233-247
    • Stollg, G.1    Jander, S.2
  • 77
    • 56349166510 scopus 로고    scopus 로고
    • PPAR ligands inhibit radiation-induced microglial inflammatory responses by negatively regulating NF- B and AP-1 pathways
    • Ramanan S., Kooshki M., Zhao W., Hsu F. C., Robbins M. E., PPAR ligands inhibit radiation-induced microglial inflammatory responses by negatively regulating NF- B and AP-1 pathways Free Radical Biology and Medicine 2008 45 12 1695 1704
    • (2008) Free Radical Biology and Medicine , vol.45 , Issue.12 , pp. 1695-1704
    • Ramanan, S.1    Kooshki, M.2    Zhao, W.3    Hsu, F.C.4    Robbins, M.E.5
  • 78
    • 73649142077 scopus 로고    scopus 로고
    • Anti-inflammatory effects of tanshinone IIA on radiation-induced microglia BV-2 cells inflammatory response
    • Dong X., Dong J., Zhang R., Fan L., Liu L., Wu G., Anti-inflammatory effects of tanshinone IIA on radiation-induced microglia BV-2 cells inflammatory response Cancer Biotherapy and Radiopharmaceuticals 2009 24 6 681 687
    • (2009) Cancer Biotherapy and Radiopharmaceuticals , vol.24 , Issue.6 , pp. 681-687
    • Dong, X.1    Dong, J.2    Zhang, R.3    Fan, L.4    Liu, L.5    Wu, G.6
  • 80
    • 0345189366 scopus 로고    scopus 로고
    • Inflammatory Blockade Restores Adult Hippocampal Neurogenesis
    • DOI 10.1126/science.1088417
    • Monje M. L., Toda H., Palmer T. D., Inflammatory blockade restores adult hippocampal neurogenesis Science 2003 302 5651 1760 1765 (Pubitemid 37505739)
    • (2003) Science , vol.302 , Issue.5651 , pp. 1760-1765
    • Monje, M.L.1    Toda, H.2    Palmer, T.D.3
  • 82
    • 0033103773 scopus 로고    scopus 로고
    • TNFα and IL-1β mediate intercellular adhesion molecule-1 induction via microglia-astrocyte interaction in CNS radiation injury
    • DOI 10.1016/S0165-5728(98)00270-7, PII S0165572898002707
    • Kyrkanides S., Olschowka J. A., Williams J. P., Hansen J. T., O'Banion M. K., TNF and IL-1 mediate intercellular adhesion molecule-1 induction via microglia-astrocyte interaction in CNS radiation injury Journal of Neuroimmunology 1999 95 1-2 95 106 (Pubitemid 29173026)
    • (1999) Journal of Neuroimmunology , vol.95 , Issue.1-2 , pp. 95-106
    • Kyrkanides, S.1    Olschowka, J.A.2    Williams, J.P.3    Hansen, J.T.4    O'Banion, M.K.5
  • 83
    • 33845604482 scopus 로고    scopus 로고
    • Administration of the peroxisomal proliferator-activated receptor γ agonist pioglitazone during fractionated brain irradiation prevents radiation-induced cognitive impairment
    • DOI 10.1016/j.ijrobp.2006.09.036, PII S0360301606031282
    • Zhao W., Payne V., Tommasi E., Diz D. I., Hsu F. C., Robbins M. E., Administration of the peroxisomal proliferator-activated receptor agonist pioglitazone during fractionated brain irradiation prevents radiation-induced cognitive impairment International Journal of Radiation Oncology Biology Physics 2007 67 1 6 9 (Pubitemid 44959517)
    • (2007) International Journal of Radiation Oncology Biology Physics , vol.67 , Issue.1 , pp. 6-9
    • Zhao, W.1    Payne, V.2    Tommasi, E.3    Diz, D.I.4    Hsu, F.-C.5    Robbins, M.E.6
  • 84
    • 34548011678 scopus 로고    scopus 로고
    • The role of glitazones in management of type 2 diabetes. A DREAM or a nightmare?
    • DOI 10.1111/j.1467-789X.2007.00399.x
    • Lindberg M., Astrup A., The role of glitazones in management of type 2 diabetes. A dream or a nightmare? Obesity Reviews 2007 8 5 381 384 (Pubitemid 47283947)
    • (2007) Obesity Reviews , vol.8 , Issue.5 , pp. 381-384
    • Lindberg, M.1    Astrup, A.2
  • 85
    • 0031015075 scopus 로고    scopus 로고
    • Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys
    • DOI 10.1038/nm0197-73
    • Crowe M. J., Bresnahan J. C., Shuman S. L., Masters J. N., Beattie M. S., Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys Nature Medicine 1997 3 1 73 76 (Pubitemid 27019144)
    • (1997) Nature Medicine , vol.3 , Issue.1 , pp. 73-76
    • Crowe, M.J.1    Bresnahan, J.C.2    Shuman, S.L.3    Masters, J.N.4    Beattie, M.S.5
  • 86
    • 16244384670 scopus 로고    scopus 로고
    • Inflammatory-mediated injury and repair in the traumatically injured spinal cord
    • DOI 10.2174/1381612053507468
    • Jones T. B., McDaniel E. E., Popovich P. G., Inflammatory-mediated injury and repair in the traumatically injured spinal cord Current Pharmaceutical Design 2005 11 10 1223 1236 (Pubitemid 40458268)
    • (2005) Current Pharmaceutical Design , vol.11 , Issue.10 , pp. 1223-1236
    • Jones, T.B.1    McDaniel, E.E.2    Popovich, P.G.3
  • 87
    • 1842419475 scopus 로고    scopus 로고
    • Degenerative and regenerative mechanisms governing spinal cord injury
    • DOI 10.1016/j.nbd.2003.11.015, PII S0969996103002523
    • Profyris C., Cheema S. S., Zang D., Azari M. F., Boyle K., Petratos S., Degenerative and regenerative mechanisms governing spinal cord injury Neurobiology of Disease 2004 15 3 415 436 (Pubitemid 38429958)
    • (2004) Neurobiology of Disease , vol.15 , Issue.3 , pp. 415-436
    • Profyris, C.1    Cheema, S.S.2    Zang, D.3    Azari, M.F.4    Boyle, K.5    Petratos, S.6
  • 88
    • 84855430333 scopus 로고    scopus 로고
    • GW0742, A High Affinity Ppar- Gonist, Mediates Protection in an Organotypic Model of Spinal Cord Damage
    • In press
    • Esposito E., Paterniti I., Meli R., Bramanti P., Cuzzocrea S., GW0742, A High Affinity Ppar- Gonist, Mediates Protection in an Organotypic Model of Spinal Cord Damage. Spine. In press
    • Spine
    • Esposito, E.1    Paterniti, I.2    Meli, R.3    Bramanti, P.4    Cuzzocrea, S.5
  • 89
    • 0035873062 scopus 로고    scopus 로고
    • Proliferation of NG2-positive cells and altered oligodendrocyte numbers in the contused rat spinal cord
    • McTigue D. M., Wei P., Stokes B. T., Proliferation of NG2-positive cells and altered oligodendrocyte numbers in the contused rat spinal cord Journal of Neuroscience 2001 21 10 3392 3400 (Pubitemid 32422804)
    • (2001) Journal of Neuroscience , vol.21 , Issue.10 , pp. 3392-3400
    • McTigue, D.M.1    Wei, P.2    Stokes, B.T.3
  • 90
    • 77949413835 scopus 로고    scopus 로고
    • Chronic expression of PPAR- by oligodendrocyte lineage cells in the injured rat spinal cord
    • Almad A., McTigue D. M., Chronic expression of PPAR- by oligodendrocyte lineage cells in the injured rat spinal cord Journal of Comparative Neurology 2010 518 6 785 799
    • (2010) Journal of Comparative Neurology , vol.518 , Issue.6 , pp. 785-799
    • Almad, A.1    McTigue, D.M.2


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