The role of phospholipase A2 in neuronal homeostasis and memory formation: Implications for the pathogenesis of Alzheimer's disease

Journal of Neural Transmission

Volumn 114, Issue 2, 2007, Pages 231-238

  Forlenza, O V ^a   Schaeffer, E L ^a   Gattaz, W F ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Alzheimer's disease; Hippocampus; Memory; Neurobiology; Phospholipase A2; Phospholipids

Indexed keywords

ACETYLSALICYLIC ACID; AMYLOID BETA PROTEIN; BROMOENOL LACTONE; CELECOXIB; CYCLOOXYGENASE 2 INHIBITOR; DAPSONE; DICLOFENAC; FLURBIPROFEN; HYDROXYCHLOROQUINE; IBUPROFEN; INDOMETACIN; METHYLARACHIDONYLFLUOROPHOSPHONATE; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR; PHOSPHOLIPID; PREDNISONE; ROFECOXIB; SULINDAC; UNCLASSIFIED DRUG; PHOSPHOLIPASE A;

ALZHEIMER DISEASE; ANISOTROPY; BRAIN CORTEX; BRAIN SLICE; DRUG MECHANISM; ENZYME ACTIVITY; HIPPOCAMPUS; HOMEOSTASIS; HUMAN; LONG TERM MEMORY; LONG TERM POTENTIATION; MEMORY DISORDER; MINI MENTAL STATE EXAMINATION; NERVE CELL DIFFERENTIATION; NERVE CELL PLASTICITY; NERVE DEGENERATION; NERVE FIBER GROWTH; NONHUMAN; PATHOGENESIS; PHOSPHOLIPID METABOLISM; PRIORITY JOURNAL; RAT STRAIN; REVIEW; THROMBOCYTE MEMBRANE; ANIMAL; ENZYMOLOGY; MEMORY; METABOLISM; NERVE CELL; PATHOPHYSIOLOGY; PHYSIOLOGY; THROMBOCYTE;

ALZHEIMER DISEASE; ANIMALS; BLOOD PLATELETS; HIPPOCAMPUS; HOMEOSTASIS; HUMANS; MEMORY; NEURONAL PLASTICITY; NEURONS; PHOSPHOLIPASES A; PHOSPHOLIPIDS;

EID: 33846452220     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-006-0597-0     Document Type: Review

References (72)

1. 2 by bromoenol lactone and trifluoromethyl ketones J Biol Chem 270 1 445 450
2. 2 Annu Rev Pharmacol Toxicol 39 175 189
3. J Bernard A Lahsaini G Massicotte 1994 Potassium-induced long-term potentiation in area CA1 of the hippocampus involves phospholipase activation Hippocampus 4 4 447 453
4. TV Bliss GL Collingridge 1993 A synaptic model of memory: long-term potentiation in the hippocampus Nature 361 6407 31 39
5. JK Blusztajn M Liscovitch C Mauron UI Richardson RJ Wurtman 1987 Phosphatidylcholine as a precursor of choline for acetylcholine synthesis J Neural Transm 24 Suppl 247 259
6. GG Brown SR Levine JM Gorell JW Pettegrew JW Gdowski JA Bueri JA Helpern KM Welch 1989 In vivo 31P NMR profiles of Alzheimer's disease and multiple subcortical infarct dementia Neurology 39 11 1423 1427
7. GG Brown JH Garcia JW Gdowski SR Levine JA Helpern 1993 Altered brain energy metabolism in demented patients with multiple subcortical ischemic lesions. Working hypotheses Arch Neurol 50 4 384 388
8. GL Caporaso SE Gandy JD Buxbaum TV Ramabhadran P Greengard 1992 Protein phosphorylation regulates secretion of Alzheimer beta/A4 amyloid precursor protein Proc Natl Acad Sci USA 89 7 3055 3059
9. S Chakraborti 2003 Phospholipase A(2) isoforms: a perspective Cell Signal 15 7 637 665
10. MS Clarke MA Prendergast AV Terry Jr 1999 Plasma membrane ordering agent pluronic F-68 (PF-68) reduces neurotransmitter uptake and release and produces learning and memory deficits in rats Learn Mem 6 6 634 649
11. MP Clements TV Bliss MA Lynchl 1991 Increase in arachidonic acid concentration in a postsynaptic membrane fraction following the induction of long-term potentiation in the dentate gyrus Neuroscience 45 2 379 389
12. 2 J Biol Chem 269 18 13057 13060
13. GP Eckert NJ Cairns A Maras WF Gattaz WE Müller 2000 Cholesterol modulates the membrane-disordering effects of beta-amyloid peptides in the hippocampus: specific changes in Alzheimer's disease Dement Geriatr Cogn Disord 11 4 181 186
14. 2 activation influences the processing and secretion of the amyloid precursor protein Biochem Biophys Res Commun 197 1 292 297
15. MR Emmerling DT Dudley RD Dyer RT Carroll PD Doyle RE Davis 1996 The role of arachidonic acid in the secretion of the amyloid precursor protein (APP) Ann NY Acad Sci 777 310 315
16. 2 and its role in brain tissue J Neurochem 69 3 889 901
17. 2 activity: their neurochemical effects and therapeutical importance for neurological disorders Brain Res Bull 49 3 139 153
18. R Fluhrer A Capell G Westmeyer M Willem B Hartung MM Condron DB Teplow C Haass J Walter 2002 A non-amyloidogenic function of BACE-2 in the secretory pathway J Neurochem 81 5 1011 1020
19. 2 activity in rat embryonic brain and in primary cultures of cortical neurons J Neural Transm 109 5-6 623 631
20. OV Forlenza P Wacker PV Nunes J Yacubian CC Castro MC Otaduy WF Gattaz 2005 Reduced phospholipid breakdown in Alzheimer's brains: a (31)P spectroscopy study Psychopharmacology (Berl) 180 2 359 365
21. 2 inhibitor impairs spatial memory of mice Jpn J Pharmacol 83 3 277 278
22. S Fujita Y Ikegaya M Nishikawa N Nishiyama N Matsuki 2001 Docosahexaenoic acid improves long-term potentiation attenuated by phospholipase A(2) inhibitor in rat hippocampal slices Br J Pharmacol 132 7 1417 1422
23. D Fukushima M Konishi K Maruyama T Miyamoto S Ishiura K Suzuki 1993 Activation of the secretory pathway leads to a decrease in the intracellular amyloidogenic fragments generated from the amyloid protein precursor Biochem Biophys Res Commun 194 1 202 207
24. 2 activity in Alzheimer brains Biol Psychiatry 37 1 13 17
25. 2 activity in the brain and in platelets of patients with Alzheimer's disease Eur Arch Psychiatry Clin Neurosci 246 3 129 131
26. WF Gattaz OV Forlenza LL Talib NR Barbosa CM Bottino 2004 Platelet phospholipase A(2) activity in Alzheimer's disease and mild cognitive impairment J Neural Transm 111 5 591 601
27. RG Gonzalez AR Guimaraes GJ Moore A Crawley LA Cupples JH Growdon 1996 Quantitative in vivo 31P magnetic resonance spectroscopy of Alzheimer disease Alzheimer Dis Assoc Disord 10 1 46 52
28. 2 produce amnesia for a passive avoidance task in the chick Behav Neural Biol 61 3 225 232
29. 2 and NO synthase cooperate in producing amnesia of a spatial task Neuroreport 6 5 730 732
30. A Hong 1995 The neural basis of learning and memory declines in aged rats Sheng Li Ke Xue Jin Zhan 26 3 240 242
31. TC Hwang SE Guggino WB Guggino 1990 Direct modulation of secretory chloride channels by arachidonic and other cis unsaturated fatty acids Proc Natl Acad Sci USA 87 15 5706 5709
32. A Ikemoto T Kobayashi S Watanabe H Okuyama 1997 Membrane fatty acid modifications of PC12 cells by arachidonate or docosahexaenoate affect neurite outgrowth but not norepinephrine release Neurochem Res 22 6 671 678
33. I Izquierdo JH Medina 1997 Memory formation: the sequence of biochemical events in the hippocampus and its connection to activity in other brain structures Neurobiol Learn Mem 68 3 285 316
34. K Kadoyama Y Takahashi H Higashida T Tanabe T Yoshimoto 2000 Cyclooxygenase-2 stimulates production of amyloid beta-peptide in neuroblastoma x glioma hybrid NG108-15 cells Biochem Biophys Res Commun 281 2 483 490
35. D Kim DE Clapham 1989 Potassium channels in cardiac cells activated by arachidonic acid and phospholipids Science 244 4909 1174 1176
36. 2 enzymes Prostaglandins Other Lipid Mediat 68-69 3 58
37. 2 and their effect on enzyme activity J Biol Chem 273 1 207 214
38. WJ Lukiw NG Bazan 2000 Neuroinflammatory signaling upregulation in Alzheimer's disease Neurochem Res 25 9-10 1173 1184
39. JC Maire RJ Wurtman 1985 Effects of electrical stimulation and choline availability on the release and contents of acetylcholine and choline in superfused slices from rat striatum J Physiol (Paris) 80 3 189 195
40. DJ Mancuso CM Jenkins RW Gross 2000 The genomic organization, complete mRNA sequence, cloning, and expression of a novel human intracellular membrane-associated calcium-independent phospholipase A(2) J Biol Chem 275 14 9937 9945
41. BM McGahon DS Martin DF Horrobin MA Lynch 1999 Age-related changes in synaptic function: analysis of the effect of dietary supplementation with omega-3 fatty acids Neuroscience 94 1 305 314
42. CT Mendes WF Gattaz EL Schaeffer OV Forlenza 2005 Modulation of phosopholipase A(2) activity in primary cultures of rat cortical neurons J Neural Transm 112 10 1297 308
43. B Miller M Sarantis SF Traynelis D Attwell 1992 Potentiation of NMDA receptor currents by arachidonic acid Nature 355 6362 722 725
44. WE Müller S Koch K Scheuer A Rostock R Bartsch 1997 Effects of piracetam on membrane fluidity in the aged mouse, rat, and human brain Biochem Pharmacol 53 2 135 140
45. JH Musser AF Kreft 1992 5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors J Med Chem 35 14 2501 2524
46. M Nishikawa S Kimura N Akaike 1994 Facilitatory effect of docosahexaenoic acid on N-methyl-D-aspartate response in pyramidal neurones of rat cerebral cortex J Physiol 475 1 83 93
47. T Nishizaki T Nomura T Matsuoka Y Tsujishita 1999 Arachidonic acid as a messenger for the expression of long-term potentiation Biochem Biophys Res Commun 254 2 446 449
48. RM Nitsch A Deng RJ Wurtman JH Growdon 1997 Metabotropic glutamate receptor subtype mGluR1alpha stimulates the secretion of the amyloid beta-protein precursor ectodomain J Neurochem 69 2 704 712
49. JW Pettegrew P Kanagasabai J Moossy J Martinez G Rao F Boller 1988 Correlation of phosphorus-31 magnetic resonance spectroscopy and morphologic findings in Alzheimer's disease Arch Neurol 45 1093 1096
50. JW Pettegrew WE Klunk E Kanal K Panchalingam RJ McClure 1995 Changes in brain membrane phospholipid and high-energy phosphate metabolism precede dementia Neurobiol Aging 16 6 973 975
51. 2 knockout mouse J Lipid Res 44 1 109 117
52. 2 activity J Neurochem 70 2 786 793
53. 2 activity in rat hippocampus impairs acquisition of short- and long-term memory Psychopharmacology (Berl) 181 2 392 400
54. 2 activity reduces membrane fluidity in rat hippocampus J Neural Transm 112 5 641 647
55. K Scheuer A Rostock R Bartsch WE Müller 1999 Piracetam improves cognitive performance by restoring neurochemical deficits of the aged rat brain Pharmacopsychiatry 32 Suppl 1 10 16
56. DA Six EA Dennis 2000 The expanding superfamily of phospholipase A(2) enzymes: classification and characterization Biochim Biophys Acta 1488 1-2 1 19
57. ER Skinner C Watt JAO Besson PV Best 1989 Lipid composition of different regions of the brain in patients with Alzheimer's disease Biochem Soc Trans 17 213 214
58. 2-derived arachidonic acid and its metabolites Brain Res 721 1-2 39 48
59. CD Smith LG Gallenstein WJ Layton RJ Kryscio WR Markesbery 1993 31P magnetic resonance spectroscopy in Alzheimer's and Pick's disease Neurobiol Aging 14 1 85 92
60. CD Stubbs AD Smith 1984 The modification of mammalian membrane polyunsaturated fatty acid composition in relation to membrane fluidity and function Biochim Biophys Acta 779 1 89 137
61. 2 in the central nervous system: implications for neurodegenerative diseases J Lipid Res 45 205 213
62. 2 activity in the prefrontal cortex Neurochem Int 37 1 17 31
63. H Tanaka R Takeya H Sumimoto 2000 A novel intracellular membrane-bound calcium-independent phospholipase A(2) Biochem Biophys Res Commun 272 2 320 326
64. 2 J Biol Chem 273 34 21926 21932
65. 2 activation and phospholipid breakdown in rat hippocampus Naunyn Schmiedebergs Arch Pharmacol 360 6 609 615
66. EJ Williams FS Walsh P Doherty 1994 The production of arachidonic acid can account for calcium channel activation in the second messenger pathway underlying neurite outgrowth stimulated by NCAM, N-cadherin, and L1 J Neurochem 62 3 1231 1234
67. MV Winstead J Balsinde EA Dennis 2000 Calcium-independent phospholipase A(2): structure and function Biochim Biophys Acta 1488 1-2 28 39
68. 2 FEBS Lett 377 3 358 362
69. 2 from cytosol to membranes in rat brain induced by calcium ions Biochem Biophys Res Commun 170 2 484 490
70. 2 activity in rat brain Biochem Biophys Res Commun 185 1 350 355
71. Y Yoshikai 2001 Roles of prostaglandins and leukotrienes in acute inflammation caused by bacterial infection Curr Opin Infect Dis 14 3 257 263
72. GS Zubenko E Winwood B Jacobs I Teply JS Stiffler HB Hughes 3rd FJ Huff T Sunderland AJ Martinez 1999 Prospective study of risk factors for Alzheimer's disease: results at 7.5 years Am J Psychiatry 156 1 50 57