Antimetastatic potential of cardiotoxin III involves inactivation of PI3K/Akt and p38 MAPK signaling pathways in human breast cancer MDA-MB-231 cells

Life Sciences

Volumn 90, Issue 1-2, 2012, Pages 54-65

  Lin, Kuei Li ^a   Chien, Ching Ming ^a   Hsieh, Chi Ying ^a   Tsai, Pei Chien ^a   Chang, Long Sen ^b   Lin, Shinne Ren ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

Author keywords

CTX III; MDA MB 231 cells; Metastasis; NF B; p38; PI3K Akt

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CARDIOTOXIN; CARDIOTOXIN 3; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; WORTMANNIN;

ARTICLE; BIOCHEMISTRY; BREAST CANCER; CANCER CELL; CELL INVASION; CELL MIGRATION; CELL VIABILITY; CYTOTOXICITY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL SURVIVAL; COBRA CARDIOTOXIN PROTEINS; FEMALE; HUMANS; MAP KINASE SIGNALING SYSTEM; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 84655160821     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2011.10.020     Document Type: Article

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