Schisandrin B suppresses TGFβ1 signaling by inhibiting Smad2/3 and MAPK pathways

Biochemical Pharmacology

Volumn 83, Issue 3, 2012, Pages 378-384

  Park, Eun Jung ^a   Chun, Jung Nyeo ^a   Kim, Su Hwa ^a   Kim, Chul Young ^b   Lee, Hee Ju ^b   Kim, Hye Kyung ^c   Park, Jong Kwan ^c   Lee, Sung Won ^d   So, Insuk ^a   Jeon, Ju Hong ^a  

^a Seoul National University   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

^c Jeonbuk National University Medical School and Hospital   (South Korea)

^d Sungkyunkwan University   (South Korea)

Author keywords

Schisandra chinensis; Schisandrin B; TGF 1; Vascular fibrotic disease; Vascular smooth muscle cell

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; SCHISANDRA CHINENSIS EXTRACT; SCHIZANDRIN B; SMAD2 PROTEIN; SMAD3 PROTEIN; SYNAPTOPHYSIN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SCHISANDRA CHINENSIS; SMOOTH MUSCLE FIBER; VASCULAR FIBROSIS;

ANIMALS; CELL LINE; CYCLOOCTANES; LIGNANS; MITOGEN-ACTIVATED PROTEIN KINASES; PLANT EXTRACTS; POLYCYCLIC COMPOUNDS; RATS; SCHISANDRA; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84455202322     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2011.11.002     Document Type: Article

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