TGFβ mediates activation of transglutaminase 2 in response to oxidative stress that leads to protein aggregation

FASEB Journal

Volumn 22, Issue 7, 2008, Pages 2498-2507

  Shin, Dong Myung ^a   Jeon, Ju Hong ^a   Kim, Chai Wan ^a   Cho, Sung Yup ^a   Lee, Hye Jin ^a   Jang, Gi Yong ^a   Eui, Man Jeong ^a   Lee, Dong Sup ^a   Kang, Ja Heon ^b   Melino, Gerry ^c   Park, Sang Chul ^a   Kim, In Gyu ^a  

^a Seoul National University College of Medicine   (South Korea)

^b Kyung Hee University Hospital   (South Korea)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

Aging; Cataract; Protein modification

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE 2; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; CALCIUM; GUANINE NUCLEOTIDE BINDING PROTEIN; TRANSGLUTAMINASE 2;

ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LENS EPITHELIUM; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN MODIFICATION; CELL LINE; DRUG EFFECT; ENZYMOLOGY; EPITHELIUM CELL; GENETIC TRANSFECTION; LENS; METABOLISM; PHYSIOLOGY;

MUS;

CALCIUM; CELL LINE; ENZYME ACTIVATION; EPITHELIAL CELLS; GTP-BINDING PROTEINS; HUMANS; LENS, CRYSTALLINE; OXIDATIVE STRESS; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA; TRANSGLUTAMINASES;

EID: 46749089164     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.07-095455     Document Type: Article

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