메뉴 건너뛰기




Volumn 129, Issue 1, 2012, Pages 14-24

Effects of air pollutants on innate immunity: The role of Toll-like receptors and nucleotide-binding oligomerization domain-like receptors

Author keywords

air pollutant; airway; cigarette smoke; danger associated molecular pattern; diesel exhaust; host defense; inflammasome; innate immunity; lung; nanoparticles; NOD like receptor; ozone; particulate matter; pathogen associated molecular pattern; pattern recognition receptor; Toll like receptor

Indexed keywords

CIGARETTE SMOKE; INFLAMMASOME; NANOPARTICLE; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; OZONE; TOLL LIKE RECEPTOR;

EID: 84455200653     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2011.11.004     Document Type: Review
Times cited : (159)

References (87)
  • 1
    • 0040795541 scopus 로고    scopus 로고
    • US Environmental Protection Agency Last updated February 10 Accessed September 7, 2011
    • US Environmental Protection Agency. Air quality trends. Available at: http://www.epa.gov/airtrends/aqtrends.html. Last updated February 10, 2011. Accessed September 7, 2011.
    • (2011) Air Quality Trends
  • 2
    • 80155169635 scopus 로고    scopus 로고
    • American Lung Association Accessed September 7, 2011
    • American Lung Association. State of the air 2011. Available at: http://www.stateoftheair.org/2011/assets/SOTA2011.pdf. Accessed September 7, 2011.
    • State of the Air 2011
  • 3
    • 79952416685 scopus 로고    scopus 로고
    • The influence of environment, as represented by diet and air pollution, upon incidence and prevalence of wheezing illnesses in young children
    • G.R. Bloomberg The influence of environment, as represented by diet and air pollution, upon incidence and prevalence of wheezing illnesses in young children Curr Opin Allergy Clin Immunol 11 2011 144 149
    • (2011) Curr Opin Allergy Clin Immunol , vol.11 , pp. 144-149
    • Bloomberg, G.R.1
  • 4
    • 14944359140 scopus 로고    scopus 로고
    • Air pollution and allergy: You are what you breathe
    • A. Saxon, and D. Diaz-Sanchez Air pollution and allergy: you are what you breathe Nat Immunol 6 2005 223 226
    • (2005) Nat Immunol , vol.6 , pp. 223-226
    • Saxon, A.1    Diaz-Sanchez, D.2
  • 5
    • 76749139817 scopus 로고    scopus 로고
    • Environmental and occupational allergies
    • D. Peden, and C.E. Reed Environmental and occupational allergies J Allergy Clin Immunol 125 suppl 2 2010 S150 S160
    • (2010) J Allergy Clin Immunol , vol.125 , Issue.SUPPL.2
    • Peden, D.1    Reed, C.E.2
  • 6
    • 78149455372 scopus 로고    scopus 로고
    • Indoor air pollution from unprocessed solid fuels in developing countries
    • C. Kaplan Indoor air pollution from unprocessed solid fuels in developing countries Rev Environ Health 25 2010 221 242
    • (2010) Rev Environ Health , vol.25 , pp. 221-242
    • Kaplan, C.1
  • 7
    • 0025057354 scopus 로고
    • Wood-burning stoves and lower respiratory tract infection in American Indian children
    • K. Morris, M. Morgenlander, J.L. Coulehan, S. Gahagen, and V.C. Arena Wood-burning stoves and lower respiratory tract infection in American Indian children Am J Dis Child 144 1990 105 108
    • (1990) Am J Dis Child , vol.144 , pp. 105-108
    • Morris, K.1    Morgenlander, M.2    Coulehan, J.L.3    Gahagen, S.4    Arena, V.C.5
  • 9
    • 33646835372 scopus 로고    scopus 로고
    • Environmental tobacco smoke exposure: Prevalence and mechanisms of causation of infections in children
    • P. Kum-Nji, L. Meloy, and H.G. Herrod Environmental tobacco smoke exposure: prevalence and mechanisms of causation of infections in children Pediatrics 117 2006 1745 1754
    • (2006) Pediatrics , vol.117 , pp. 1745-1754
    • Kum-Nji, P.1    Meloy, L.2    Herrod, H.G.3
  • 10
    • 0031255572 scopus 로고    scopus 로고
    • Health effects of passive smoking. 1. parental smoking and lower respiratory illness in infancy and early childhood
    • D.P. Strachan, and D.G. Cook Health effects of passive smoking. 1. parental smoking and lower respiratory illness in infancy and early childhood Thorax 52 1997 905 914
    • (1997) Thorax , vol.52 , pp. 905-914
    • Strachan, D.P.1    Cook, D.G.2
  • 11
    • 41649086980 scopus 로고    scopus 로고
    • Sex differences in the impact of ozone on survival and alveolar macrophage function of mice after Klebsiella pneumoniae infection
    • A.N. Mikerov, X. Gan, T.M. Umstead, L. Miller, V.M. Chinchilli, and D.S. Phelps Sex differences in the impact of ozone on survival and alveolar macrophage function of mice after Klebsiella pneumoniae infection Respir Res 9 2008 24
    • (2008) Respir Res , vol.9 , pp. 24
    • Mikerov, A.N.1    Gan, X.2    Umstead, T.M.3    Miller, L.4    Chinchilli, V.M.5    Phelps, D.S.6
  • 12
    • 0034890672 scopus 로고    scopus 로고
    • Air pollution and hospital admissions for respiratory conditions in Rome, Italy
    • D. Fusco, F. Forastiere, P. Michelozzi, T. Spadea, B. Ostro, and M. Arca Air pollution and hospital admissions for respiratory conditions in Rome, Italy Eur Respir J 17 2001 1143 1150
    • (2001) Eur Respir J , vol.17 , pp. 1143-1150
    • Fusco, D.1    Forastiere, F.2    Michelozzi, P.3    Spadea, T.4    Ostro, B.5    Arca, M.6
  • 13
    • 18344406682 scopus 로고    scopus 로고
    • Short-term effects of air pollution on hospital admissions of respiratory diseases in Europe: A quantitative summary of APHEA study results. Air pollution and health: A European approach
    • C. Spix, H.R. Anderson, J. Schwartz, M.A. Vigotti, A. LeTertre, and J.M. Vonk Short-term effects of air pollution on hospital admissions of respiratory diseases in Europe: a quantitative summary of APHEA study results. Air pollution and health: a European approach Arch Environ Health 53 1998 54 64
    • (1998) Arch Environ Health , vol.53 , pp. 54-64
    • Spix, C.1    Anderson, H.R.2    Schwartz, J.3    Vigotti, M.A.4    Letertre, A.5    Vonk, J.M.6
  • 14
    • 0035891602 scopus 로고    scopus 로고
    • Acute effects of particulate air pollution on respiratory admissions: Results from APHEA 2 project. Air pollution and health: A European approach
    • R.W. Atkinson, H.R. Anderson, J. Sunyer, J. Ayres, M. Baccini, and J.M. Vonk Acute effects of particulate air pollution on respiratory admissions: results from APHEA 2 project. Air pollution and health: a European approach Am J Respir Crit Care Med 164 2001 1860 1866
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 1860-1866
    • Atkinson, R.W.1    Anderson, H.R.2    Sunyer, J.3    Ayres, J.4    Baccini, M.5    Vonk, J.M.6
  • 15
    • 17544366739 scopus 로고    scopus 로고
    • Traffic air pollution and hospital admission for asthma: A case-control approach in a Turin (Italy) population
    • G. Migliaretti, E. Cadum, E. Migliore, and F. Cavallo Traffic air pollution and hospital admission for asthma: a case-control approach in a Turin (Italy) population Int Arch Occup Environ Health 78 2005 164 169
    • (2005) Int Arch Occup Environ Health , vol.78 , pp. 164-169
    • Migliaretti, G.1    Cadum, E.2    Migliore, E.3    Cavallo, F.4
  • 16
    • 33748561513 scopus 로고    scopus 로고
    • The relationship of air pollution to ED visits for asthma differ between children and adults
    • H.L. Sun, M.C. Chou, and K.H. Lue The relationship of air pollution to ED visits for asthma differ between children and adults Am J Emerg Med 24 2006 709 713
    • (2006) Am J Emerg Med , vol.24 , pp. 709-713
    • Sun, H.L.1    Chou, M.C.2    Lue, K.H.3
  • 17
    • 79954456997 scopus 로고    scopus 로고
    • Lung function and inflammatory responses in healthy young adults exposed to 0.06 ppm ozone for 6.6 hours
    • C.S. Kim, N.E. Alexis, A.G. Rappold, H. Kehrl, M.J. Hazucha, and J.C. Lay Lung function and inflammatory responses in healthy young adults exposed to 0.06 ppm ozone for 6.6 hours Am J Respir Crit Care Med 183 2011 1215 1221
    • (2011) Am J Respir Crit Care Med , vol.183 , pp. 1215-1221
    • Kim, C.S.1    Alexis, N.E.2    Rappold, A.G.3    Kehrl, H.4    Hazucha, M.J.5    Lay, J.C.6
  • 18
    • 69449096686 scopus 로고    scopus 로고
    • Involvement of TLR2 and TLR4 in inflammatory immune responses induced by fine and coarse ambient air particulate matter
    • J. Shoenfelt, R.J. Mitkus, R. Zeisler, R.O. Spatz, J. Powell, and M.J. Fenton Involvement of TLR2 and TLR4 in inflammatory immune responses induced by fine and coarse ambient air particulate matter J Leukoc Biol 86 2009 303 312
    • (2009) J Leukoc Biol , vol.86 , pp. 303-312
    • Shoenfelt, J.1    Mitkus, R.J.2    Zeisler, R.3    Spatz, R.O.4    Powell, J.5    Fenton, M.J.6
  • 19
    • 33845951211 scopus 로고    scopus 로고
    • DAMPs, PAMPs and alarmins: All we need to know about danger
    • M.E. Bianchi DAMPs, PAMPs and alarmins: all we need to know about danger J Leukoc Biol 81 2007 1 5
    • (2007) J Leukoc Biol , vol.81 , pp. 1-5
    • Bianchi, M.E.1
  • 20
    • 78649335026 scopus 로고    scopus 로고
    • The role of toll-like receptors in acute and chronic lung inflammation
    • E.I. Lafferty, S.T. Qureshi, and M. Schnare The role of toll-like receptors in acute and chronic lung inflammation J Inflamm (Lond) 7 2010 57
    • (2010) J Inflamm (Lond) , vol.7 , pp. 57
    • Lafferty, E.I.1    Qureshi, S.T.2    Schnare, M.3
  • 22
    • 77950343791 scopus 로고    scopus 로고
    • Pattern recognition receptors and inflammation
    • O. Takeuchi, and S. Akira Pattern recognition receptors and inflammation Cell 140 2010 805 820
    • (2010) Cell , vol.140 , pp. 805-820
    • Takeuchi, O.1    Akira, S.2
  • 23
    • 79959369407 scopus 로고    scopus 로고
    • The role of oxidative stress and innate immunity in O(3) and endotoxin-induced human allergic airway disease
    • D.B. Peden The role of oxidative stress and innate immunity in O(3) and endotoxin-induced human allergic airway disease Immunol Rev 242 2011 91 105
    • (2011) Immunol Rev , vol.242 , pp. 91-105
    • Peden, D.B.1
  • 24
    • 34548459895 scopus 로고    scopus 로고
    • Structure, function and regulation of the Toll/IL-1 receptor adaptor proteins
    • T.M. Watters, E.F. Kenny, and L.A. O'Neill Structure, function and regulation of the Toll/IL-1 receptor adaptor proteins Immunol Cell Biol 85 2007 411 419
    • (2007) Immunol Cell Biol , vol.85 , pp. 411-419
    • Watters, T.M.1    Kenny, E.F.2    O'Neill, L.A.3
  • 26
    • 5444262511 scopus 로고    scopus 로고
    • Toll-like receptor control of the adaptive immune responses
    • A. Iwasaki, and R. Medzhitov Toll-like receptor control of the adaptive immune responses Nat Immunol 5 2004 987 995
    • (2004) Nat Immunol , vol.5 , pp. 987-995
    • Iwasaki, A.1    Medzhitov, R.2
  • 27
    • 65649141586 scopus 로고    scopus 로고
    • Pathogen recognition in the innate immune response
    • H. Kumar, T. Kawai, and S. Akira Pathogen recognition in the innate immune response Biochem J 420 2009 1 16
    • (2009) Biochem J , vol.420 , pp. 1-16
    • Kumar, H.1    Kawai, T.2    Akira, S.3
  • 28
    • 56549116047 scopus 로고    scopus 로고
    • Toll-like receptor and RIG-I-like receptor signaling
    • T. Kawai, and S. Akira Toll-like receptor and RIG-I-like receptor signaling Ann N Y Acad Sci 1143 2008 1 20
    • (2008) Ann N y Acad Sci , vol.1143 , pp. 1-20
    • Kawai, T.1    Akira, S.2
  • 29
    • 34548656855 scopus 로고    scopus 로고
    • Signaling pathways downstream of pattern-recognition receptors and their cross talk
    • M.S. Lee, and Y.J. Kim Signaling pathways downstream of pattern-recognition receptors and their cross talk Annu Rev Biochem 76 2007 447 480
    • (2007) Annu Rev Biochem , vol.76 , pp. 447-480
    • Lee, M.S.1    Kim, Y.J.2
  • 30
    • 34247566510 scopus 로고    scopus 로고
    • The family of five: TIR-domain-containing adaptors in toll-like receptor signalling
    • L.A. O'Neill, and A.G. Bowie The family of five: TIR-domain-containing adaptors in toll-like receptor signalling Nat Rev Immunol 7 2007 353 364
    • (2007) Nat Rev Immunol , vol.7 , pp. 353-364
    • O'Neill, L.A.1    Bowie, A.G.2
  • 31
    • 30744462300 scopus 로고    scopus 로고
    • Regulation of lung injury and repair by toll-like receptors and hyaluronan
    • D. Jiang, J. Liang, J. Fan, S. Yu, S. Chen, and Y. Luo Regulation of lung injury and repair by toll-like receptors and hyaluronan Nat Med 11 2005 1173 1179
    • (2005) Nat Med , vol.11 , pp. 1173-1179
    • Jiang, D.1    Liang, J.2    Fan, J.3    Yu, S.4    Chen, S.5    Luo, Y.6
  • 32
    • 33747483267 scopus 로고    scopus 로고
    • The role of toll-like receptors in non-infectious lung injury
    • D. Jiang, J. Liang, Y. Li, and P.W. Noble The role of toll-like receptors in non-infectious lung injury Cell Res 16 2006 693 701
    • (2006) Cell Res , vol.16 , pp. 693-701
    • Jiang, D.1    Liang, J.2    Li, Y.3    Noble, P.W.4
  • 33
    • 4444221545 scopus 로고    scopus 로고
    • A TLR4 polymorphism is associated with asthma and reduced lipopolysaccharide-induced interleukin-12(p70) responses in Swedish children
    • M. Fageras Bottcher, M. Hmani-Aifa, A. Lindstrom, M.C. Jenmalm, X.M. Mai, and L. Nilsson A TLR4 polymorphism is associated with asthma and reduced lipopolysaccharide-induced interleukin-12(p70) responses in Swedish children J Allergy Clin Immunol 114 2004 561 567
    • (2004) J Allergy Clin Immunol , vol.114 , pp. 561-567
    • Fageras Bottcher, M.1    Hmani-Aifa, M.2    Lindstrom, A.3    Jenmalm, M.C.4    Mai, X.M.5    Nilsson, L.6
  • 34
    • 77953444175 scopus 로고    scopus 로고
    • Genetic variation in toll-like receptor signalling and the risk of inflammatory and immune diseases
    • S.C. Corr, and L.A. O'Neill Genetic variation in toll-like receptor signalling and the risk of inflammatory and immune diseases J Innate Immun 1 2009 350 357
    • (2009) J Innate Immun , vol.1 , pp. 350-357
    • Corr, S.C.1    O'Neill, L.A.2
  • 35
    • 77956354815 scopus 로고    scopus 로고
    • Atopic asthmatic subjects but not atopic subjects without asthma have enhanced inflammatory response to ozone
    • e1
    • M.L. Hernandez, J.C. Lay, B. Harris, C.R. Esther Jr., W.J. Brickey, and P.A. Bromberg Atopic asthmatic subjects but not atopic subjects without asthma have enhanced inflammatory response to ozone J Allergy Clin Immunol 126 2010 537 544 e1
    • (2010) J Allergy Clin Immunol , vol.126 , pp. 537-544
    • Hernandez, M.L.1    Lay, J.C.2    Harris, B.3    Esther Jr., C.R.4    Brickey, W.J.5    Bromberg, P.A.6
  • 36
    • 33744787332 scopus 로고    scopus 로고
    • Diesel exhaust enhances virus- and poly(I: C)-induced toll-like receptor 3 expression and signaling in respiratory epithelial cells
    • J. Ciencewicki, L. Brighton, W.D. Wu, M. Madden, and I. Jaspers Diesel exhaust enhances virus- and poly(I: C)-induced toll-like receptor 3 expression and signaling in respiratory epithelial cells Am J Physiol Lung Cell Mol Physiol 290 2006 L1154 L1163
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.290
    • Ciencewicki, J.1    Brighton, L.2    Wu, W.D.3    Madden, M.4    Jaspers, I.5
  • 37
    • 79957933703 scopus 로고    scopus 로고
    • Cigarette smoke suppresses TLR-7 stimulation in response to virus infection in plasmacytoid dendritic cells
    • S.M. Castro, K. Chakraborty, and A. Guerrero-Plata Cigarette smoke suppresses TLR-7 stimulation in response to virus infection in plasmacytoid dendritic cells Toxicol In Vitro 25 2011 1106 1113
    • (2011) Toxicol in Vitro , vol.25 , pp. 1106-1113
    • Castro, S.M.1    Chakraborty, K.2    Guerrero-Plata, A.3
  • 38
    • 78349268377 scopus 로고    scopus 로고
    • Cigarette smoke induces CXCL8 production by human neutrophils via activation of TLR9 receptor
    • E. Mortaz, I.M. Adcock, K. Ito, A.D. Kraneveld, F.P. Nijkamp, and G. Folkerts Cigarette smoke induces CXCL8 production by human neutrophils via activation of TLR9 receptor Eur Respir J 36 2010 1143 1154
    • (2010) Eur Respir J , vol.36 , pp. 1143-1154
    • Mortaz, E.1    Adcock, I.M.2    Ito, K.3    Kraneveld, A.D.4    Nijkamp, F.P.5    Folkerts, G.6
  • 39
    • 0032888567 scopus 로고    scopus 로고
    • Role of soluble metals in oil fly ash-induced airway epithelial injury and cytokine gene expression
    • J.A. Dye, K.B. Adler, J.H. Richards, and K.L. Dreher Role of soluble metals in oil fly ash-induced airway epithelial injury and cytokine gene expression Am J Physiol Lung Cell Mol Physiol 277 1999 L498 L510
    • (1999) Am J Physiol Lung Cell Mol Physiol , vol.277
    • Dye, J.A.1    Adler, K.B.2    Richards, J.H.3    Dreher, K.L.4
  • 40
    • 0036847266 scopus 로고    scopus 로고
    • Involvement of microbial components and toll-like receptors 2 and 4 in cytokine responses to air pollution particles
    • S. Becker, M.J. Fenton, and J.M. Soukup Involvement of microbial components and toll-like receptors 2 and 4 in cytokine responses to air pollution particles Am J Respir Cell Mol Biol 27 2002 611 618
    • (2002) Am J Respir Cell Mol Biol , vol.27 , pp. 611-618
    • Becker, S.1    Fenton, M.J.2    Soukup, J.M.3
  • 41
    • 53149117055 scopus 로고    scopus 로고
    • Effect of polycyclic aromatic hydrocarbons and carbon black particles on pro-inflammatory cytokine secretion: Impact of PAH coating onto particles
    • S. Goulaouic, L. Foucaud, A. Bennasroune, P. Laval-Gilly, and J. Falla Effect of polycyclic aromatic hydrocarbons and carbon black particles on pro-inflammatory cytokine secretion: impact of PAH coating onto particles J Immunotoxicol 5 2008 337 345
    • (2008) J Immunotoxicol , vol.5 , pp. 337-345
    • Goulaouic, S.1    Foucaud, L.2    Bennasroune, A.3    Laval-Gilly, P.4    Falla, J.5
  • 42
    • 33750842912 scopus 로고    scopus 로고
    • Exposure to airborne particulate matter in the ambient, indoor, and occupational environments
    • P.K. Hopke, and A. Rossner Exposure to airborne particulate matter in the ambient, indoor, and occupational environments Clin Occup Environ Med 5 2006 747 771
    • (2006) Clin Occup Environ Med , vol.5 , pp. 747-771
    • Hopke, P.K.1    Rossner, A.2
  • 43
    • 33645858755 scopus 로고    scopus 로고
    • The role of toll-like receptor 4 in airway inflammation induced by diesel exhaust particles
    • K. Inoue, H. Takano, R. Yanagisawa, S. Hirano, T. Ichinose, and A. Shimada The role of toll-like receptor 4 in airway inflammation induced by diesel exhaust particles Arch Toxicol 80 2006 275 279
    • (2006) Arch Toxicol , vol.80 , pp. 275-279
    • Inoue, K.1    Takano, H.2    Yanagisawa, R.3    Hirano, S.4    Ichinose, T.5    Shimada, A.6
  • 46
    • 33846829873 scopus 로고    scopus 로고
    • Ambient particulate matter directs nonclassic dendritic cell activation and a mixed TH1/TH2-like cytokine response by naive CD4+ T cells
    • M.A. Williams, M. Porter, M. Horton, J. Guo, J. Roman, and D. Williams Ambient particulate matter directs nonclassic dendritic cell activation and a mixed TH1/TH2-like cytokine response by naive CD4+ T cells J Allergy Clin Immunol 119 2007 488 497
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 488-497
    • Williams, M.A.1    Porter, M.2    Horton, M.3    Guo, J.4    Roman, J.5    Williams, D.6
  • 47
    • 40449118020 scopus 로고    scopus 로고
    • Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent
    • E. Doz, N. Noulin, E. Boichot, I. Guenon, L. Fick, and M. Le Bert Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent J Immunol 180 2008 1169 1178
    • (2008) J Immunol , vol.180 , pp. 1169-1178
    • Doz, E.1    Noulin, N.2    Boichot, E.3    Guenon, I.4    Fick, L.5    Le Bert, M.6
  • 48
    • 69749097391 scopus 로고    scopus 로고
    • Cigarette smoke attenuates the production of cytokines by human plasmacytoid dendritic cells and enhances the release of IL-8 in response to TLR-9 stimulation
    • E. Mortaz, Z. Lazar, L. Koenderman, A.D. Kraneveld, F.P. Nijkamp, and G. Folkerts Cigarette smoke attenuates the production of cytokines by human plasmacytoid dendritic cells and enhances the release of IL-8 in response to TLR-9 stimulation Respir Res 10 2009 47
    • (2009) Respir Res , vol.10 , pp. 47
    • Mortaz, E.1    Lazar, Z.2    Koenderman, L.3    Kraneveld, A.D.4    Nijkamp, F.P.5    Folkerts, G.6
  • 49
    • 44849090900 scopus 로고    scopus 로고
    • Cigarette smoke increases toll-like receptor 4 and modifies lipopolysaccharide-mediated responses in airway epithelial cells
    • E. Pace, M. Ferraro, L. Siena, M. Melis, A.M. Montalbano, and M. Johnson Cigarette smoke increases toll-like receptor 4 and modifies lipopolysaccharide- mediated responses in airway epithelial cells Immunology 124 2008 401 411
    • (2008) Immunology , vol.124 , pp. 401-411
    • Pace, E.1    Ferraro, M.2    Siena, L.3    Melis, M.4    Montalbano, A.M.5    Johnson, M.6
  • 52
    • 0034029244 scopus 로고    scopus 로고
    • Genetic susceptibility to ozone-induced lung hyperpermeability: Role of toll-like receptor 4
    • S.R. Kleeberger, S. Reddy, L.Y. Zhang, and A.E. Jedlicka Genetic susceptibility to ozone-induced lung hyperpermeability: role of toll-like receptor 4 Am J Respir Cell Mol Biol 22 2000 620 627
    • (2000) Am J Respir Cell Mol Biol , vol.22 , pp. 620-627
    • Kleeberger, S.R.1    Reddy, S.2    Zhang, L.Y.3    Jedlicka, A.E.4
  • 54
    • 0031954974 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced alveolar epithelial permeability: The role of nitric oxide
    • X.Y. Li, K. Donaldson, and W. MacNee Lipopolysaccharide-induced alveolar epithelial permeability: the role of nitric oxide Am J Respir Crit Care Med 157 1998 1027 1033
    • (1998) Am J Respir Crit Care Med , vol.157 , pp. 1027-1033
    • Li, X.Y.1    Donaldson, K.2    MacNee, W.3
  • 56
    • 0030039522 scopus 로고    scopus 로고
    • The effect of ozone exposure on allergen responsiveness in subjects with asthma or rhinitis
    • R. Jorres, D. Nowak, and H. Magnussen The effect of ozone exposure on allergen responsiveness in subjects with asthma or rhinitis Am J Respir Crit Care Med 153 1996 56 64
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 56-64
    • Jorres, R.1    Nowak, D.2    Magnussen, H.3
  • 57
  • 59
    • 79961085857 scopus 로고    scopus 로고
    • Identification of candidate genes downstream of TLR4 signaling after ozone exposure in mice: A role for heat-shock protein 70
    • A.K. Bauer, E.A. Rondini, K.A. Hummel, L.M. Degraff, C. Walker, and A.E. Jedlicka Identification of candidate genes downstream of TLR4 signaling after ozone exposure in mice: a role for heat-shock protein 70 Environ Health Perspect 119 2011 1091 1097
    • (2011) Environ Health Perspect , vol.119 , pp. 1091-1097
    • Bauer, A.K.1    Rondini, E.A.2    Hummel, K.A.3    Degraff, L.M.4    Walker, C.5    Jedlicka, A.E.6
  • 60
    • 33845890803 scopus 로고    scopus 로고
    • Inflammasome adaptors and sensors: Intracellular regulators of infection and inflammation
    • S. Mariathasan, and D.M. Monack Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation Nat Rev Immunol 7 2007 31 40
    • (2007) Nat Rev Immunol , vol.7 , pp. 31-40
    • Mariathasan, S.1    Monack, D.M.2
  • 61
    • 77957228318 scopus 로고    scopus 로고
    • Central roles of NLRs and inflammasomes in viral infection
    • T.D. Kanneganti Central roles of NLRs and inflammasomes in viral infection Nat Rev Immunol 10 2010 688 698
    • (2010) Nat Rev Immunol , vol.10 , pp. 688-698
    • Kanneganti, T.D.1
  • 62
    • 60749104683 scopus 로고    scopus 로고
    • The inflammasome: A caspase-1-activation platform that regulates immune responses and disease pathogenesis
    • L. Franchi, T. Eigenbrod, R. Munoz-Planillo, and G. Nunez The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis Nat Immunol 10 2009 241 247
    • (2009) Nat Immunol , vol.10 , pp. 241-247
    • Franchi, L.1    Eigenbrod, T.2    Munoz-Planillo, R.3    Nunez, G.4
  • 63
    • 77957575480 scopus 로고    scopus 로고
    • The role of the inflammasome in nonmyeloid cells
    • A.S. Yazdi, S.K. Drexler, and J. Tschopp The role of the inflammasome in nonmyeloid cells J Clin Immunol 30 2010 623 627
    • (2010) J Clin Immunol , vol.30 , pp. 623-627
    • Yazdi, A.S.1    Drexler, S.K.2    Tschopp, J.3
  • 64
    • 79952159132 scopus 로고    scopus 로고
    • Emerging inflammasome effector mechanisms
    • M. Lamkanfi Emerging inflammasome effector mechanisms Nat Rev Immunol 11 2011 213 220
    • (2011) Nat Rev Immunol , vol.11 , pp. 213-220
    • Lamkanfi, M.1
  • 65
    • 80052179138 scopus 로고    scopus 로고
    • Caspase-1-induced pyroptotic cell death
    • E.A. Miao, J.V. Rajan, and A. Aderem Caspase-1-induced pyroptotic cell death Immunol Rev 243 2011 206 214
    • (2011) Immunol Rev , vol.243 , pp. 206-214
    • Miao, E.A.1    Rajan, J.V.2    Aderem, A.3
  • 66
    • 77649179433 scopus 로고    scopus 로고
    • NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production?
    • J. Tschopp, and K. Schroder NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production? Nat Rev Immunol 10 2010 210 215
    • (2010) Nat Rev Immunol , vol.10 , pp. 210-215
    • Tschopp, J.1    Schroder, K.2
  • 67
    • 66749174867 scopus 로고    scopus 로고
    • The inflammasomes: Guardians of the body
    • F. Martinon, A. Mayor, and J. Tschopp The inflammasomes: guardians of the body Annu Rev Immunol 27 2009 229 265
    • (2009) Annu Rev Immunol , vol.27 , pp. 229-265
    • Martinon, F.1    Mayor, A.2    Tschopp, J.3
  • 68
    • 34548027736 scopus 로고    scopus 로고
    • Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
    • V. Petrilli, S. Papin, C. Dostert, A. Mayor, F. Martinon, and J. Tschopp Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration Cell Death Differ 14 2007 1583 1589
    • (2007) Cell Death Differ , vol.14 , pp. 1583-1589
    • Petrilli, V.1    Papin, S.2    Dostert, C.3    Mayor, A.4    Martinon, F.5    Tschopp, J.6
  • 70
    • 43249125839 scopus 로고    scopus 로고
    • Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
    • C. Dostert, V. Petrilli, R. Van Bruggen, C. Steele, B.T. Mossman, and J. Tschopp Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica Science 320 2008 674 677
    • (2008) Science , vol.320 , pp. 674-677
    • Dostert, C.1    Petrilli, V.2    Van Bruggen, R.3    Steele, C.4    Mossman, B.T.5    Tschopp, J.6
  • 71
    • 75649096002 scopus 로고    scopus 로고
    • Thioredoxin-interacting protein links oxidative stress to inflammasome activation
    • R. Zhou, A. Tardivel, B. Thorens, I. Choi, and J. Tschopp Thioredoxin-interacting protein links oxidative stress to inflammasome activation Nat Immunol 11 2010 136 140
    • (2010) Nat Immunol , vol.11 , pp. 136-140
    • Zhou, R.1    Tardivel, A.2    Thorens, B.3    Choi, I.4    Tschopp, J.5
  • 72
    • 79953046719 scopus 로고    scopus 로고
    • The inflammasome NLRs in immunity, inflammation, and associated diseases
    • B.K. Davis, H. Wen, and J.P. Ting The inflammasome NLRs in immunity, inflammation, and associated diseases Annu Rev Immunol 29 2011 707 735
    • (2011) Annu Rev Immunol , vol.29 , pp. 707-735
    • Davis, B.K.1    Wen, H.2    Ting, J.P.3
  • 73
    • 80052482830 scopus 로고    scopus 로고
    • P2X7 receptor and caspase 1 activation are central to airway inflammation observed after exposure to tobacco smoke
    • S. Eltom, C.S. Stevenson, J. Rastrick, N. Dale, K. Raemdonck, and S. Wong P2X7 receptor and caspase 1 activation are central to airway inflammation observed after exposure to tobacco smoke PLoS One 6 2011 e24097
    • (2011) PLoS One , vol.6 , pp. 24097
    • Eltom, S.1    Stevenson, C.S.2    Rastrick, J.3    Dale, N.4    Raemdonck, K.5    Wong, S.6
  • 74
    • 47849097202 scopus 로고    scopus 로고
    • Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
    • V. Hornung, F. Bauernfeind, A. Halle, E.O. Samstad, H. Kono, and K.L. Rock Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization Nat Immunol 9 2008 847 856
    • (2008) Nat Immunol , vol.9 , pp. 847-856
    • Hornung, V.1    Bauernfeind, F.2    Halle, A.3    Samstad, E.O.4    Kono, H.5    Rock, K.L.6
  • 75
    • 78650610580 scopus 로고    scopus 로고
    • Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1alpha and IL-1beta
    • A.S. Yazdi, G. Guarda, N. Riteau, S.K. Drexler, A. Tardivel, and I. Couillin Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1alpha and IL-1beta Proc Natl Acad Sci U S A 107 2010 19449 19454
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 19449-19454
    • Yazdi, A.S.1    Guarda, G.2    Riteau, N.3    Drexler, S.K.4    Tardivel, A.5    Couillin, I.6
  • 79
    • 29644439882 scopus 로고    scopus 로고
    • Mechanisms underlying nano-sized air-pollution-mediated progression of atherosclerosis: Carbon black causes cytotoxic injury/inflammation and inhibits cell growth in vascular endothelial cells
    • H. Yamawaki, and N. Iwai Mechanisms underlying nano-sized air-pollution-mediated progression of atherosclerosis: carbon black causes cytotoxic injury/inflammation and inhibits cell growth in vascular endothelial cells Circ J 70 2006 129 140
    • (2006) Circ J , vol.70 , pp. 129-140
    • Yamawaki, H.1    Iwai, N.2
  • 83
    • 64049111768 scopus 로고    scopus 로고
    • The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA
    • I.C. Allen, M.A. Scull, C.B. Moore, E.K. Holl, E. McElvania-TeKippe, and D.J. Taxman The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA Immunity 30 2009 556 565
    • (2009) Immunity , vol.30 , pp. 556-565
    • Allen, I.C.1    Scull, M.A.2    Moore, C.B.3    Holl, E.K.4    McElvania-Tekippe, E.5    Taxman, D.J.6
  • 86
    • 14044267522 scopus 로고    scopus 로고
    • Involvement of toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded RNA and influenza A virus
    • L. Guillot, R. Le Goffic, S. Bloch, N. Escriou, S. Akira, and M. Chignard Involvement of toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded RNA and influenza A virus J Biol Chem 280 2005 5571 5580
    • (2005) J Biol Chem , vol.280 , pp. 5571-5580
    • Guillot, L.1    Le Goffic, R.2    Bloch, S.3    Escriou, N.4    Akira, S.5    Chignard, M.6
  • 87
    • 79951943733 scopus 로고    scopus 로고
    • S42 airway epithelial toll receptor expression in asthma and its relationship to disease severity
    • L. Cottey, N. Jayasekera, H. Haitchi, B. Green, C. Grainge, and P. Howarth S42 airway epithelial toll receptor expression in asthma and its relationship to disease severity Thorax 65 2010 A21 A22
    • (2010) Thorax , vol.65
    • Cottey, L.1    Jayasekera, N.2    Haitchi, H.3    Green, B.4    Grainge, C.5    Howarth, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.