메뉴 건너뛰기




Volumn 69, Issue 10, 2009, Pages 4277-4285

Retraction: A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation (Cancer Research (2009) 69 (4277-4285) DOI: 10.1158/0008-5472.CAN-08-3669);A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; MESSENGER RNA; N [4 (2 AMINO 6 METHYLPYRIMIDIN 4 YLAMINO)PHENYL] 4 (QUINOLIN 4 YLAMINO)BENZAMIDE; PROTEASOME; PROTEIN MLH1; PROTEIN P16; QUINOLINE DERIVATIVE; S ADENOSYLMETHIONINE; SGI 1027; TISSUE INHIBITOR OF METALLOPROTEINASE 3; UNCLASSIFIED DRUG;

EID: 66249127951     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-23-2366     Document Type: Erratum
Times cited : (237)

References (49)
  • 1
    • 43749098985 scopus 로고    scopus 로고
    • DNA methylation landscapes: Provocative insights from epigenomics
    • Suzuki MM, Bird A. DNA methylation landscapes: provocative insights from epigenomics. Nat Rev Genet 2008;9:465-476
    • (2008) Nat Rev Genet , vol.9 , pp. 465-476
    • Suzuki, M.M.1    Bird, A.2
  • 2
    • 33644846509 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer-a mechanism for early oncogenic pathway addiction?
    • Baylin SB, Ohm JE. Epigenetic gene silencing in cancer-a mechanism for early oncogenic pathway addiction? Nat Rev Cancer 2006;6:107-116
    • (2006) Nat Rev Cancer , vol.6 , pp. 107-116
    • Baylin, S.B.1    Ohm, J.E.2
  • 3
    • 1042278765 scopus 로고    scopus 로고
    • The history of cancer epigenetics
    • Feinberg AP, Tycko B. The history of cancer epigenetics. Nat Rev Cancer 2004;4:143-153 (Pubitemid 38198742)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.2 , pp. 143-153
    • Feinberg, A.P.1    Tycko, B.2
  • 4
    • 44949233068 scopus 로고    scopus 로고
    • Proteins that bind methylated DNA and human cancer: Reading the wrong words
    • Lopez-Serra L, Esteller M. Proteins that bind methylated DNA and human cancer: reading the wrong words. Br J Cancer 2008;98:1881-1885
    • (2008) Br J Cancer , vol.98 , pp. 1881-1885
    • Lopez-Serra, L.1    Esteller, M.2
  • 6
    • 9144256125 scopus 로고    scopus 로고
    • The Dnmt1 DNA-(cytosine-C5)-methyltransferase methylates DNA processively with high preference for hemimethylated target sites
    • DOI 10.1074/jbc.M403427200
    • Hermann A, Goyal R, Jeltsch A. The Dnmt1 DNA-(cytosine-C5)- methyltransferase methylates DNA processively with high preference for hemimethylated target sites. J Biol Chem 2004;279:48350-48359 (Pubitemid 39540991)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.46 , pp. 48350-48359
    • Hermann, A.1    Goyal, R.2    Jeltsch, A.3
  • 7
    • 34547799171 scopus 로고    scopus 로고
    • DNA methyltransferases as targets for cancer therapy
    • DOI 10.1358/dot.2007.43.6.1062666
    • Ghoshal K, Bai S. DNA methyltransferases as targets for cancer therapy. Drugs Today (Barc) 2007;43:395-422. (Pubitemid 47234771)
    • (2007) Drugs of Today , vol.43 , Issue.6 , pp. 395-422
    • Ghoshal, K.1    Bai, S.2
  • 9
    • 41849128470 scopus 로고    scopus 로고
    • Constrained analogues of procaine as novel small molecule inhibitors of DNA methyltransferase-1
    • Castellano S, Kuck D, Sala M, et al. Constrained analogues of procaine as novel small molecule inhibitors of DNA methyltransferase-1. J Med Chem 2008;51:2321-2325
    • (2008) J Med Chem , vol.51 , pp. 2321-2325
    • Castellano, S.1    Kuck, D.2    Sala, M.3
  • 10
    • 36849090114 scopus 로고    scopus 로고
    • Epigenetic regulation: A new research area for melatonin?
    • Korkmaz A, Reiter RJ. Epigenetic regulation: a new research area for melatonin? J Pineal Res 2008;44:41-44
    • (2008) J Pineal Res , vol.44 , pp. 41-44
    • Korkmaz, A.1    Reiter, R.J.2
  • 11
    • 45049086493 scopus 로고    scopus 로고
    • 2′-Deoxy-N4-2-(4-nitrophenyl)ethoxycarbonyl-5-azacytidine: A novel inhibitor of DNA methyltransferase that requires activation by human carboxylesterase 1
    • Byun HM, Choi SH, Laird PW, et al. 2′-Deoxy-N4-2-(4-nitrophenyl) ethoxycarbonyl]-5-azacytidine: a novel inhibitor of DNA methyltransferase that requires activation by human carboxylesterase 1. Cancer Lett 2008;266:238-248
    • (2008) Cancer Lett , vol.266 , pp. 238-248
    • Byun, H.M.1    Choi, S.H.2    Laird, P.W.3
  • 13
    • 0025368584 scopus 로고
    • Inhibition of EcoRI DNA methylase with cofactor analogs
    • Reich NO, Mashhoon N. Inhibition of EcoRI DNA methylase with cofactor analogs. J Biol Chem 1990;265:8966-8970 (Pubitemid 20167422)
    • (1990) Journal of Biological Chemistry , vol.265 , Issue.15 , pp. 8966-8970
    • Reich, N.O.1    Mashhoon, N.2
  • 14
    • 28244493491 scopus 로고    scopus 로고
    • Physical and functional interaction of DNA methyltransferase 3A with Mbd3 and Brg1 in mouse lymphosarcoma cells
    • DOI 10.1158/0008-5472.CAN-05-1455
    • Datta J, Majumder S, Bai S, et al. Physical and functional interaction of DNA methyltransferase 3A with Mbd3 and Brg1 in mouse lymphosarcoma cells. Cancer Res 2005;65:10891-10900 (Pubitemid 41713357)
    • (2005) Cancer Research , vol.65 , Issue.23 , pp. 10891-10900
    • Datta, J.1    Majumder, S.2    Bai, S.3    Ghoshal, K.4    Kutay, H.5    Smith, D.S.6    Crabb, J.W.7    Jacob, S.T.8
  • 16
    • 18944383889 scopus 로고    scopus 로고
    • 5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signal
    • DOI 10.1128/MCB.25.11.4727-4741.2005
    • Ghoshal K, Datta J, Majumder S, et al. 5-Azadeoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signal. Mol Cell Biol 2005;25:4727-4741 (Pubitemid 40705775)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.11 , pp. 4727-4741
    • Ghoshal, K.1    Datta, J.2    Majumder, S.3    Bai, S.4    Kutay, H.5    Motiwala, T.6    Jacob, S.T.7
  • 17
    • 33744950175 scopus 로고    scopus 로고
    • Identification of T-cadherin as a novel target of DNA methyltransferase 3B and its role in the suppression of nerve growth factor-mediated neurite outgrowth in PC12 cells
    • DOI 10.1074/jbc.M513278200
    • Bai S, Ghoshal K, Jacob ST. Identification of T-cadherin as a novel target of DNA methyltransferase 3B and its role in the suppression of nerve growth factor-mediated neurite outgrowth in PC12 cells. J Biol Chem 2006;281:13604-13611 (Pubitemid 43855275)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.19 , pp. 13604-13611
    • Bai, S.1    Ghoshal, K.2    Jacob, S.T.3
  • 18
    • 0034614381 scopus 로고    scopus 로고
    • Suppression of metallothionein gene expression in a rat hepatoma because of promoter-specific DNA methylation
    • DOI 10.1074/jbc.275.1.539
    • Ghoshal K, Majumder S, Li Z, Dong X, Jacob ST. Suppression of metallothionein gene expression in a rat hepatoma because of promoter-specific DNA methylation. J Biol Chem 2000;275:539-547 (Pubitemid 30039016)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.1 , pp. 539-547
    • Ghoshal, K.1    Majumder, S.2    Li, Z.3    Dong, X.4    Jacob, S.T.5
  • 19
    • 0033523885 scopus 로고    scopus 로고
    • Silencing of metallothionein-I gene in mouse lymphosarcoma cells by methylation
    • Majumder S, Ghoshal K, Li Z, Bo Y, Jacob ST. Silencing of metallothionein-I gene in mouse lymphosarcoma cells by methylation. Oncogene 1999;18:6287-6295
    • (1999) Oncogene , vol.18 , pp. 6287-6295
    • Majumder, S.1    Ghoshal, K.2    Li, Z.3    Bo, Y.4    Jacob, S.T.5
  • 22
    • 0033558192 scopus 로고    scopus 로고
    • Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggests a suppressor role in kidney, brain, and other human cancers
    • Bachman KE, Herman JG, Corn PG, et al. Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggest a suppressor role in kidney, brain, and other human cancers. Cancer Res 1999;59:798-802. (Pubitemid 29086729)
    • (1999) Cancer Research , vol.59 , Issue.4 , pp. 798-802
    • Bachman, K.E.1    Herman, J.G.2    Corn, P.G.3    Merlo, A.4    Costello, J.F.5    Cavenee, W.K.6    Baylin, S.B.7    Graff, J.R.8
  • 23
  • 24
    • 0037013280 scopus 로고    scopus 로고
    • Role of de novo DNA methyltransferases and methyl CpG-binding proteins in gene silencing in a rat hepatoma
    • Majumder S, Ghoshal K, Datta J, et al. Role of de novo DNA methyltransferases and methyl CpG-binding proteins in gene silencing in a rat hepatoma. J Biol Chem 2002;277:16048-16058
    • (2002) J Biol Chem , vol.277 , pp. 16048-16058
    • Majumder, S.1    Ghoshal, K.2    Datta, J.3
  • 26
    • 0026769202 scopus 로고
    • Two-dimensional NMR studies of d(GGTTAATGCGGT). (ACCGCATTAACC) complexed with the minor groove binding drug SN-6999
    • Chen SM, Leupin W, Rance M, Chazin WJ. Two-dimensional NMR studies of d(GGTTAATGCGGT). (ACCGCATTAACC) complexed with the minor groove binding drug SN-6999. Biochemistry 1992;31:4406-4413
    • (1992) Biochemistry , vol.31 , pp. 4406-4413
    • Chen, S.M.1    Leupin, W.2    Rance, M.3    Chazin, W.J.4
  • 27
    • 32944473776 scopus 로고    scopus 로고
    • Structures of two minor-groove-binding quinolinium quaternary salts complexed with d(CGCGAATTCGCG)(2) at 1.6 and 1.8 Angstrom resolution
    • Adams A, Leong C, Denny WA, Guss JM. Structures of two minor-groove-binding quinolinium quaternary salts complexed with d(CGCGAATTCGCG)(2) at 1.6 and 1.8 Angstrom resolution. Acta Crystallogr D Biol Crystallogr 2005;61:1348-1353
    • (2005) Acta Crystallogr D Biol Crystallogr , vol.61 , pp. 1348-1353
    • Adams, A.1    Leong, C.2    Denny, W.A.3    Guss, J.M.4
  • 28
    • 0018757383 scopus 로고
    • Potential antitumor agents. 29. Quantitative structure-activity relationships for the antileukemic bisquaternary ammonium heterocycles
    • Denny WA, Atwell GJ, Baguley BC, Cain BF. Potential antitumor agents. 29. Quantitative structure-activity relationships for the antileukemic bisquaternary ammonium heterocycles. J Med Chem 1979;22:134-150
    • (1979) J Med Chem , vol.22 , pp. 134-150
    • Denny, W.A.1    Atwell, G.J.2    Baguley, B.C.3    Cain, B.F.4
  • 29
    • 15744401773 scopus 로고    scopus 로고
    • Eukaryotic cytosine methyltransferases
    • DOI 10.1146/annurev.biochem.74.010904.153721
    • Goll MG, Bestor TH. Eukaryotic cytosine methyltransferases. Annu Rev Biochem 2005;74:481-514. (Pubitemid 40995515)
    • (2005) Annual Review of Biochemistry , vol.74 , pp. 481-514
    • Goll, M.G.1    Bestor, T.H.2
  • 30
    • 0037376690 scopus 로고    scopus 로고
    • Biochemical fractionation reveals association of DNA methyltransferase (Dnmt) 3b with Dnmt1 and that of Dnmt 3a with a histone H3 methyltransferase and Hdac1
    • DOI 10.1002/jcb.10457
    • Datta J, Ghoshal K, Sharma SM, Tajima S, Jacob ST. Biochemical fractionation reveals association of DNA methyltransferase (Dnmt) 3b with Dnmt1 and that of Dnmt 3a with a histone H3 methyltransferase and Hdac1. J Cell Biochem 2003;88:855-864 (Pubitemid 36337030)
    • (2003) Journal of Cellular Biochemistry , vol.88 , Issue.5 , pp. 855-864
    • Datta, J.1    Ghoshal, K.2    Sharma, S.M.3    Tajima, S.4    Jacob, S.T.5
  • 31
    • 0037068379 scopus 로고    scopus 로고
    • 5-Azacytidine and 5-aza-2′-deoxycytidine as inhibitors of DNA methylation: Mechanistic studies and their implications for cancer therapy
    • Christman JK. 5-Azacytidine and 5-aza-2′-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy. Oncogene 2002;21:5483-5495
    • (2002) Oncogene , vol.21 , pp. 5483-5495
    • Christman, J.K.1
  • 32
    • 0032948005 scopus 로고    scopus 로고
    • Synergy of demethylation and histone deacetylase inhibition in the re- Expression of genes silenced in cancer
    • DOI 10.1038/5047
    • Cameron EE, Bachman KE, Myohanen S, Herman JG, Baylin SB. Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer. Nat Genet 1999;21:103-107 (Pubitemid 29036293)
    • (1999) Nature Genetics , vol.21 , Issue.1 , pp. 103-107
    • Cameron, E.E.1    Bachman, K.E.2    Myohanen, S.3    Herman, J.G.4    Baylin, S.B.5
  • 33
    • 33645751058 scopus 로고    scopus 로고
    • Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state
    • McGarvey KM, Fahrner JA, Greene E, et al. Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state. Cancer Res 2006;66:3541-3549
    • (2006) Cancer Res , vol.66 , pp. 3541-3549
    • McGarvey, K.M.1    Fahrner, J.A.2    Greene, E.3
  • 34
    • 2942572700 scopus 로고    scopus 로고
    • Measuring reactive species and oxidative damage in vivo and in cell culture: How should you do it and what do the results mean?
    • Halliwell B, Whiteman M. Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean? Br J Pharmacol 2004;142:231-255
    • (2004) Br J Pharmacol , vol.142 , pp. 231-255
    • Halliwell, B.1    Whiteman, M.2
  • 35
    • 34547792388 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer: The DNA hypermethylome
    • DOI 10.1093/hmg/ddm018, Cancer Genetics
    • Esteller M. Epigenetic gene silencing in cancer: the DNA hypermethylome. Hum Mol Genet 2007;16 Spec No 1:R50-9. (Pubitemid 47241842)
    • (2007) Human Molecular Genetics , vol.16 , Issue.R1
    • Esteller, M.1
  • 36
    • 48549091046 scopus 로고    scopus 로고
    • Methylation mediated silencing of microRNA-1 gene and its role in hepatocellular carcinogenesis
    • Datta J, Kutay H, Nasser MW, et al. Methylation mediated silencing of microRNA-1 gene and its role in hepatocellular carcinogenesis. Cancer Res 2008;68:5049-5058
    • (2008) Cancer Res , vol.68 , pp. 5049-5058
    • Datta, J.1    Kutay, H.2    Nasser, M.W.3
  • 39
    • 5644255995 scopus 로고    scopus 로고
    • DNA methyltransferase inhibitors: Old and new drugs for an epigenetic cancer therapy
    • DOI 10.1016/j.tips.2004.09.004, PII S0165614704002548
    • Brueckner B, Lyko F. DNA methyltransferase inhibitors: old and new drugs for an epigenetic cancer therapy. Trends Pharmacol Sci 2004;25:551-554 (Pubitemid 39371143)
    • (2004) Trends in Pharmacological Sciences , vol.25 , Issue.11 , pp. 551-554
    • Brueckner, B.1    Lyko, F.2
  • 40
    • 0036889153 scopus 로고    scopus 로고
    • Inhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure
    • DOI 10.1128/MCB.22.23.8302-8319.2002
    • Ghoshal K, Datta J, Majumder S, et al. Inhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure. Mol Cell Biol 2002;22:8302-8319 (Pubitemid 35304062)
    • (2002) Molecular and Cellular Biology , vol.22 , Issue.23 , pp. 8302-8319
    • Ghoshal, K.1    Datta, J.2    Majumder, S.3    Bai, S.4    Dong, X.5    Parthun, M.6    Jacob, S.T.7
  • 42
    • 0345275879 scopus 로고    scopus 로고
    • Tea Polyphenol (-)-Epigallocatechin-3-Gallate Inhibits DNA Methyltransferase and Reactivates Methylation-Silenced Genes in Cancer Cell Lines
    • Fang MZ, Wang Y, Ai N, et al. Tea polyphenol (-)-epigallocatechin-3- gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines. Cancer Res 2003;63:7563-7570 (Pubitemid 37466673)
    • (2003) Cancer Research , vol.63 , Issue.22 , pp. 7563-7570
    • Fang, M.Z.1    Wang, Y.2    Ai, N.3    Hou, Z.4    Sun, Y.5    Lu, H.6    Welsh, W.7    Yang, C.S.8
  • 43
    • 33645086120 scopus 로고    scopus 로고
    • Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines
    • Stresemann C, Brueckner B, Musch T, Stopper H, Lyko F. Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines. Cancer Res 2006;66:2794-2800
    • (2006) Cancer Res , vol.66 , pp. 2794-2800
    • Stresemann, C.1    Brueckner, B.2    Musch, T.3    Stopper, H.4    Lyko, F.5
  • 44
    • 0041939756 scopus 로고    scopus 로고
    • Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells
    • Villar-Garea A, Fraga MF, Espada J, Esteller M. Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells. Cancer Res 2003;63:4984-4989 (Pubitemid 37022635)
    • (2003) Cancer Research , vol.63 , Issue.16 , pp. 4984-4989
    • Villar-Garea, A.1    Fraga, M.F.2    Espada, J.3    Esteller, M.4
  • 45
    • 1242272932 scopus 로고    scopus 로고
    • The absence of p53 is critical for the induction of apoptosis by 5-aza-2′-deoxycytidine
    • DOI 10.1038/sj.onc.1207175
    • Nieto M, Samper E, Fraga MF, et al. The absence of p53 is critical for the induction of apoptosis by 5-aza-2′-deoxycytidine. Oncogene 2004;23:735-743 (Pubitemid 38241274)
    • (2004) Oncogene , vol.23 , Issue.3 , pp. 735-743
    • Nieto, M.1    Samper, E.2    Fraga, M.F.3    Gonzalez De Buitrago, G.4    Esteller, M.5    Serrano, M.6
  • 47
    • 0033753779 scopus 로고    scopus 로고
    • The DNA methyltransferases of mammals
    • Bestor TH. The DNA methyltransferases of mammals. Hum Mol Genet 2000;9:2395-2402
    • (2000) Hum Mol Genet , vol.9 , pp. 2395-2402
    • Bestor, T.H.1
  • 48
    • 33847065486 scopus 로고    scopus 로고
    • The Epigenomics of Cancer
    • DOI 10.1016/j.cell.2007.01.029, PII S0092867407001274
    • Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007;128:683-692 (Pubitemid 46273572)
    • (2007) Cell , vol.128 , Issue.4 , pp. 683-692
    • Jones, P.A.1    Baylin, S.B.2
  • 49
    • 33846142183 scopus 로고    scopus 로고
    • HDAC inhibitors overcome first hurdle
    • DOI 10.1038/nbt0107-17, PII NBT010717
    • Garber K. HDAC inhibitors overcome first hurdle. Nat Biotechnol 2007;25:17-19 (Pubitemid 46087886)
    • (2007) Nature Biotechnology , vol.25 , Issue.1 , pp. 17-19
    • Garber, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.