-
1
-
-
0030249097
-
Function of ets genes is conserved between vertebrates and Drosophila
-
Albagli O, Klaes A, Ferreira E, Leprince D, Klämbt C. 1996. Function of ets genes is conserved between vertebrates and Drosophila. Mech Dev 59: 29-40.
-
(1996)
Mech Dev
, vol.59
, pp. 29-40
-
-
Albagli, O.1
Klaes, A.2
Ferreira, E.3
Leprince, D.4
Klämbt, C.5
-
2
-
-
33745043072
-
The ADAM metalloprotease Kuzbanian is crucial for proper heart formation in Drosophila melanogaster
-
Albrecht S, Wang S, Holz A, Bergter A, Paululat A. 2006. The ADAM metalloprotease Kuzbanian is crucial for proper heart formation in Drosophila melanogaster. Mech Dev 123: 372-387.
-
(2006)
Mech Dev
, vol.123
, pp. 372-387
-
-
Albrecht, S.1
Wang, S.2
Holz, A.3
Bergter, A.4
Paululat, A.5
-
3
-
-
0026635184
-
Deformed autoregulatory element from Drosophila functions in a conserved manner in transgenic mice
-
Awgulewitsch A, Jacobs D. 1992. Deformed autoregulatory element from Drosophila functions in a conserved manner in transgenic mice. Nature 358: 341-344.
-
(1992)
Nature
, vol.358
, pp. 341-344
-
-
Awgulewitsch, A.1
Jacobs, D.2
-
4
-
-
0033782266
-
GFP and beta-galactosidase transformation vectors for promoter/enhancer analysis in Drosophila
-
728, 730, 732.
-
Barolo S, Carver L, Posakony J. 2000. GFP and beta-galactosidase transformation vectors for promoter/enhancer analysis in Drosophila. Biotechniques 29: 726, 728, 730, 732.
-
(2000)
Biotechniques
, vol.29
, pp. 726
-
-
Barolo, S.1
Carver, L.2
Posakony, J.3
-
5
-
-
0030636780
-
Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndrome
-
Basson C, Bachinsky D, Lin R, Levi T, Elkins J, Soults J, Grayzel D, Kroumpouzou E, Traill T, Leblanc-Straceski J, Renault B, Kucherlapati R, Seidman J, Seidman C. 1997. Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndrome. Nat Genet 15: 30-35.
-
(1997)
Nat Genet
, vol.15
, pp. 30-35
-
-
Basson, C.1
Bachinsky, D.2
Lin, R.3
Levi, T.4
Elkins, J.5
Soults, J.6
Grayzel, D.7
Kroumpouzou, E.8
Traill, T.9
Leblanc-Straceski, J.10
Renault, B.11
Kucherlapati, R.12
Seidman, J.13
Seidman, C.14
-
6
-
-
35949001344
-
Genome-wide screen for modifiers of ataxin-3 neurodegeneration in Drosophila
-
Bilen J, Bonini N. 2007. Genome-wide screen for modifiers of ataxin-3 neurodegeneration in Drosophila. PLoS Genet 3: 1950-1964.
-
(2007)
PLoS Genet
, vol.3
, pp. 1950-1964
-
-
Bilen, J.1
Bonini, N.2
-
7
-
-
0027160708
-
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
-
Brand AH, Perrimon N. 1993. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development (Cambridge, England) 118: 401-415.
-
(1993)
Development (Cambridge, England)
, vol.118
, pp. 401-415
-
-
Brand, A.H.1
Perrimon, N.2
-
8
-
-
8444245525
-
A phylogenetically conserved cis-regulatory module in the Msx2 promoter is sufficient for BMP-dependent transcription in murine and Drosophila embryos
-
Brugger SM, Merrill AE, Torres-Vazquez J, Wu N, Ting M-C, Cho JY-M, Dobias SL, Yi SE, Lyons K, Bell JR, Arora K, Warrior R, Maxson R. 2004. A phylogenetically conserved cis-regulatory module in the Msx2 promoter is sufficient for BMP-dependent transcription in murine and Drosophila embryos. Development (Cambridge, England) 131: 5153-5165.
-
(2004)
Development (Cambridge, England)
, vol.131
, pp. 5153-5165
-
-
Brugger, S.M.1
Merrill, A.E.2
Torres-Vazquez, J.3
Wu, N.4
Ting, M.-C.5
Cho, J.-M.6
Dobias, S.L.7
Yi, S.E.8
Lyons, K.9
Bell, J.R.10
Arora, K.11
Warrior, R.12
Maxson, R.13
-
9
-
-
17944378083
-
A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease
-
Bruneau B, Nemer G, Schmitt J, Charron F, Robitaille L, Caron S, Conner D, Gessler M, Nemer M, Seidman C, Seidman J. 2001. A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease. Cell 106: 709-721.
-
(2001)
Cell
, vol.106
, pp. 709-721
-
-
Bruneau, B.1
Nemer, G.2
Schmitt, J.3
Charron, F.4
Robitaille, L.5
Caron, S.6
Conner, D.7
Gessler, M.8
Nemer, M.9
Seidman, C.10
Seidman, J.11
-
10
-
-
0032431822
-
Functional dominance among Hox genes: repression dominates activation in the regulation of Dpp
-
Capovilla M, Botas J. 1998. Functional dominance among Hox genes: repression dominates activation in the regulation of Dpp. Development 125: 4949-4957.
-
(1998)
Development
, vol.125
, pp. 4949-4957
-
-
Capovilla, M.1
Botas, J.2
-
11
-
-
0028173682
-
Direct regulation of decapentaplegic by Ultrabithorax and its role in Drosophila midgut morphogenesis
-
Capovilla M, Brandt M, Botas J. 1994. Direct regulation of decapentaplegic by Ultrabithorax and its role in Drosophila midgut morphogenesis. Cell 76: 461-475.
-
(1994)
Cell
, vol.76
, pp. 461-475
-
-
Capovilla, M.1
Brandt, M.2
Botas, J.3
-
12
-
-
0035030742
-
Direct regulation of the muscle-identity gene apterous by a Hox protein in the somatic mesoderm
-
Capovilla M, Kambris Z, Botas J. 2001. Direct regulation of the muscle-identity gene apterous by a Hox protein in the somatic mesoderm. Development 128: 1221-1230.
-
(2001)
Development
, vol.128
, pp. 1221-1230
-
-
Capovilla, M.1
Kambris, Z.2
Botas, J.3
-
13
-
-
21844463045
-
Alpha-myosin heavy chain: a sarcomeric gene associated with dilated and hypertrophic phenotypes of cardiomyopathy
-
Carniel E, Taylor MRG, Sinagra G, Di Lenarda A, Ku L, Fain PR, Boucek MM, Cavanaugh J, Miocic S, Slavov D, Graw SL, Feiger J, Zhu XZ, Dao D, Ferguson DA, Bristow MR, Mestroni L. 2005. Alpha-myosin heavy chain: a sarcomeric gene associated with dilated and hypertrophic phenotypes of cardiomyopathy. Circulation 112: 54-59.
-
(2005)
Circulation
, vol.112
, pp. 54-59
-
-
Carniel, E.1
Taylor, M.R.G.2
Sinagra, G.3
Di Lenarda, A.4
Ku, L.5
Fain, P.R.6
Boucek, M.M.7
Cavanaugh, J.8
Miocic, S.9
Slavov, D.10
Graw, S.L.11
Feiger, J.12
Zhu, X.Z.13
Dao, D.14
Ferguson, D.A.15
Bristow, M.R.16
Mestroni, L.17
-
14
-
-
0027966927
-
The DNA binding specificity of Ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein
-
Chan S, Jaffe L, Capovilla M, Botas J, Mann R. 1994. The DNA binding specificity of Ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein. Cell 78: 603-615.
-
(1994)
Cell
, vol.78
, pp. 603-615
-
-
Chan, S.1
Jaffe, L.2
Capovilla, M.3
Botas, J.4
Mann, R.5
-
15
-
-
20144387341
-
Mutation in myosin heavy chain 6 causes atrial septal defect
-
Ching Y, Ghosh T, Cross S, Packham E, Honeyman L, Loughna S, Robinson T, Dearlove A, Ribas G, Bonser A, Thomas N, Scotter A, Caves L, Tyrrell G, Newbury-Ecob R, Munnich A, Bonnet D, Brook J. 2005. Mutation in myosin heavy chain 6 causes atrial septal defect. Nat Genet 37: 423-428.
-
(2005)
Nat Genet
, vol.37
, pp. 423-428
-
-
Ching, Y.1
Ghosh, T.2
Cross, S.3
Packham, E.4
Honeyman, L.5
Loughna, S.6
Robinson, T.7
Dearlove, A.8
Ribas, G.9
Bonser, A.10
Thomas, N.11
Scotter, A.12
Caves, L.13
Tyrrell, G.14
Newbury-Ecob, R.15
Munnich, A.16
Bonnet, D.17
Brook, J.18
-
16
-
-
0034662018
-
Chamber formation and morphogenesis in the developing mammalian heart
-
Christoffels V, Habets P, Franco D, Campione M, de Jong F, Lamers W, Bao Z, Palmer S, Biben C, Harvey R, Moorman A. 2000. Chamber formation and morphogenesis in the developing mammalian heart. Dev Biol 223: 266-278.
-
(2000)
Dev Biol
, vol.223
, pp. 266-278
-
-
Christoffels, V.1
Habets, P.2
Franco, D.3
Campione, M.4
de Jong, F.5
Lamers, W.6
Bao, Z.7
Palmer, S.8
Biben, C.9
Harvey, R.10
Moorman, A.11
-
17
-
-
33645957354
-
Transcription factors and congenital heart defects
-
Clark K, Yutzey K, Benson D. 2006. Transcription factors and congenital heart defects. Annu Rev Physiol 68: 97-121.
-
(2006)
Annu Rev Physiol
, vol.68
, pp. 97-121
-
-
Clark, K.1
Yutzey, K.2
Benson, D.3
-
18
-
-
52949111357
-
Genetic modifiers of MeCP2 function in Drosophila
-
Cukier H, Perez A, Collins A, Zhou Z, Zoghbi H, Botas J. 2008. Genetic modifiers of MeCP2 function in Drosophila. PLoS Genet 4: e1000179.
-
(2008)
PLoS Genet
, vol.4
-
-
Cukier, H.1
Perez, A.2
Collins, A.3
Zhou, Z.4
Zoghbi, H.5
Botas, J.6
-
19
-
-
0033166065
-
Functional complementation of the malvolio mutation in the taste pathway of Drosophila melanogaster by the human natural resistance-associated macrophage protein 1 (Nramp-1)
-
D'Souza J, Cheah PY, Gros P, Chia W, Rodrigues V. 1999. Functional complementation of the malvolio mutation in the taste pathway of Drosophila melanogaster by the human natural resistance-associated macrophage protein 1 (Nramp-1). J Exp Biol 202: 1909-1915.
-
(1999)
J Exp Biol
, vol.202
, pp. 1909-1915
-
-
D'Souza, J.1
Cheah, P.Y.2
Gros, P.3
Chia, W.4
Rodrigues, V.5
-
20
-
-
0030939115
-
The human transcription enhancer factor-1, TEF-1, can substitute for Drosophila scalloped during wingblade development
-
Deshpande N, Chopra A, Rangarajan A, Shashidhara LS, Rodrigues V, Krishna S. 1997. The human transcription enhancer factor-1, TEF-1, can substitute for Drosophila scalloped during wingblade development. J Biol Chem 272: 10664-10668.
-
(1997)
J Biol Chem
, vol.272
, pp. 10664-10668
-
-
Deshpande, N.1
Chopra, A.2
Rangarajan, A.3
Shashidhara, L.S.4
Rodrigues, V.5
Krishna, S.6
-
21
-
-
0029779002
-
The atrial natriuretic factor promoter is a downstream target for Nkx-2.5 in the myocardium
-
Durocher D, Chen C, Ardati A, Schwartz R, Nemer M. 1996. The atrial natriuretic factor promoter is a downstream target for Nkx-2.5 in the myocardium. Mol Cell Biol 16: 4648-4655.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 4648-4655
-
-
Durocher, D.1
Chen, C.2
Ardati, A.3
Schwartz, R.4
Nemer, M.5
-
22
-
-
0030799792
-
The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors
-
Durocher D, Charron F, Warren R, Schwartz R, Nemer M. 1997. The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors. Embo J 16: 5687-5696.
-
(1997)
Embo J
, vol.16
, pp. 5687-5696
-
-
Durocher, D.1
Charron, F.2
Warren, R.3
Schwartz, R.4
Nemer, M.5
-
23
-
-
0037424497
-
Functional analysis of TBX5 missense mutations associated with Holt-Oram syndrome
-
Fan C, Liu M, Wang Q. 2003. Functional analysis of TBX5 missense mutations associated with Holt-Oram syndrome. J Biol Chem 278: 8780-8785.
-
(2003)
J Biol Chem
, vol.278
, pp. 8780-8785
-
-
Fan, C.1
Liu, M.2
Wang, Q.3
-
24
-
-
0034597833
-
Identification of genes that modify ataxin-1-induced neurodegeneration
-
Fernandez-Funez P, Nino-Rosales M, de Gouyon B, She W, Luchak J, Martinez P, Turiegano E, Benito J, Capovilla M, Skinner P, McCall A, Canal I, Orr H, Zoghbi H, Botas J. 2000. Identification of genes that modify ataxin-1-induced neurodegeneration. Nature 408: 101-106.
-
(2000)
Nature
, vol.408
, pp. 101-106
-
-
Fernandez-Funez, P.1
Nino-Rosales, M.2
de Gouyon, B.3
She, W.4
Luchak, J.5
Martinez, P.6
Turiegano, E.7
Benito, J.8
Capovilla, M.9
Skinner, P.10
McCall, A.11
Canal, I.12
Orr, H.13
Zoghbi, H.14
Botas, J.15
-
25
-
-
78049526266
-
The CrebA/Creb3-like transcription factors are major and direct regulators of secretory capacity
-
Fox RM, Hanlon CD, Andrew DJ. 2010. The CrebA/Creb3-like transcription factors are major and direct regulators of secretory capacity. J Cell Biol 191: 479-492.
-
(2010)
J Cell Biol
, vol.191
, pp. 479-492
-
-
Fox, R.M.1
Hanlon, C.D.2
Andrew, D.J.3
-
26
-
-
0028897837
-
Evolutionary-conserved enhancers direct region-specific expression of the murine Hoxa-1 and Hoxa-2 loci in both mice and Drosophila
-
Frasch M, Chen X, Lufkin T. 1995. Evolutionary-conserved enhancers direct region-specific expression of the murine Hoxa-1 and Hoxa-2 loci in both mice and Drosophila. Development 121: 957-974.
-
(1995)
Development
, vol.121
, pp. 957-974
-
-
Frasch, M.1
Chen, X.2
Lufkin, T.3
-
27
-
-
0031033603
-
D-mef2 is a target for Tinman activation during Drosophila heart development
-
Gajewski K, Kim Y, Lee Y, Olson E, Schulz R. 1997. D-mef2 is a target for Tinman activation during Drosophila heart development. Embo J 16: 515-522.
-
(1997)
Embo J
, vol.16
, pp. 515-522
-
-
Gajewski, K.1
Kim, Y.2
Lee, Y.3
Olson, E.4
Schulz, R.5
-
28
-
-
0033398273
-
The zinc finger proteins Pannier and GATA4 function as cardiogenic factors in Drosophila
-
Gajewski K, Fossett N, Molkentin J, Schulz R. 1999. The zinc finger proteins Pannier and GATA4 function as cardiogenic factors in Drosophila. Development 126: 5679-5688.
-
(1999)
Development
, vol.126
, pp. 5679-5688
-
-
Gajewski, K.1
Fossett, N.2
Molkentin, J.3
Schulz, R.4
-
29
-
-
0035872950
-
Pannier is a transcriptional target and partner of Tinman during Drosophila cardiogenesis
-
Gajewski K, Zhang Q, Choi C, Fossett N, Dang A, Kim Y, Kim Y, Schulz R. 2001. Pannier is a transcriptional target and partner of Tinman during Drosophila cardiogenesis. Dev Biol 233: 425-436.
-
(2001)
Dev Biol
, vol.233
, pp. 425-436
-
-
Gajewski, K.1
Zhang, Q.2
Choi, C.3
Fossett, N.4
Dang, A.5
Kim, Y.6
Kim, Y.7
Schulz, R.8
-
30
-
-
77957209962
-
Homeotic and atavic mutations in insects
-
Garcia-Bellido A. 1977. Homeotic and atavic mutations in insects. Am Zool 17:613-629.
-
(1977)
Am Zool
, vol.17
, pp. 613-629
-
-
Garcia-Bellido, A.1
-
31
-
-
0043267988
-
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
-
Garg V, Kathiriya I, Barnes R, Schluterman M, King I, Butler C, Rothrock C, Eapen R, Hirayama-Yamada K, Joo K, Matsuoka R, Cohen J, Srivastava D. 2003. GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5. Nature 424: 443-447.
-
(2003)
Nature
, vol.424
, pp. 443-447
-
-
Garg, V.1
Kathiriya, I.2
Barnes, R.3
Schluterman, M.4
King, I.5
Butler, C.6
Rothrock, C.7
Eapen, R.8
Hirayama-Yamada, K.9
Joo, K.10
Matsuoka, R.11
Cohen, J.12
Srivastava, D.13
-
32
-
-
0035445835
-
Characterization of the TBX5 binding site and analysis of mutations that cause Holt-Oram syndrome
-
Ghosh T, Packham E, Bonser A, Robinson T, Cross S, Brook J. 2001. Characterization of the TBX5 binding site and analysis of mutations that cause Holt-Oram syndrome. Hum Mol Genet 10: 1983-1994.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 1983-1994
-
-
Ghosh, T.1
Packham, E.2
Bonser, A.3
Robinson, T.4
Cross, S.5
Brook, J.6
-
33
-
-
64649085563
-
Physical interaction between TBX5 and MEF2C is required for early heart development
-
Ghosh TK, Song FF, Packham EA, Buxton S, Robinson TE, Ronksley J, Self T, Bonser AJ, Brook JD. 2009. Physical interaction between TBX5 and MEF2C is required for early heart development. Mol Cell Biol 29: 2205-2218.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 2205-2218
-
-
Ghosh, T.K.1
Song, F.F.2
Packham, E.A.3
Buxton, S.4
Robinson, T.E.5
Ronksley, J.6
Self, T.7
Bonser, A.J.8
Brook, J.D.9
-
34
-
-
0030467254
-
Intron of the mouse Hoxa-7 gene contains conserved homeodomain binding sites that can function as an enhancer element in Drosophila
-
Haerry T, Gehring W. 1996. Intron of the mouse Hoxa-7 gene contains conserved homeodomain binding sites that can function as an enhancer element in Drosophila. Proc Natl Acad Sci USA 93: 13884-13889.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 13884-13889
-
-
Haerry, T.1
Gehring, W.2
-
35
-
-
0031170789
-
A conserved cluster of homeodomain binding sites in the mouse Hoxa-4 intron functions in Drosophila embryos as an enhancer that is directly regulated by Ultrabithorax
-
Haerry T, Gehring W. 1997. A conserved cluster of homeodomain binding sites in the mouse Hoxa-4 intron functions in Drosophila embryos as an enhancer that is directly regulated by Ultrabithorax. Dev Biol 186: 1-15.
-
(1997)
Dev Biol
, vol.186
, pp. 1-15
-
-
Haerry, T.1
Gehring, W.2
-
36
-
-
0036937281
-
Transcriptional integration of competence modulated by mutual repression generates cell-type specificity within the cardiogenic mesoderm
-
Han Z, Fujioka M, Su M, Liu M, Jaynes JB, Bodmer R. 2002. Transcriptional integration of competence modulated by mutual repression generates cell-type specificity within the cardiogenic mesoderm. Dev Biol 252: 225-240.
-
(2002)
Dev Biol
, vol.252
, pp. 225-240
-
-
Han, Z.1
Fujioka, M.2
Su, M.3
Liu, M.4
Jaynes, J.B.5
Bodmer, R.6
-
37
-
-
0034931034
-
Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation
-
Hiroi Y, Kudoh S, Monzen K, Ikeda Y, Yazaki Y, Nagai R, Komuro I. 2001. Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation. Nat Genet 28: 276-280.
-
(2001)
Nat Genet
, vol.28
, pp. 276-280
-
-
Hiroi, Y.1
Kudoh, S.2
Monzen, K.3
Ikeda, Y.4
Yazaki, Y.5
Nagai, R.6
Komuro, I.7
-
38
-
-
0023651350
-
Regulation and function of the Drosophila segmentation gene fushi tarazu
-
Hiromi Y, Gehring WJ. 1987. Regulation and function of the Drosophila segmentation gene fushi tarazu. Cell 50: 963-974.
-
(1987)
Cell
, vol.50
, pp. 963-974
-
-
Hiromi, Y.1
Gehring, W.J.2
-
39
-
-
77955321344
-
Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors
-
Ieda M, Fu J-D, Delgado-Olguin P, Vedantham V, Hayashi Y, Bruneau BG, Srivastava D. 2010. Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell 142: 375-386.
-
(2010)
Cell
, vol.142
, pp. 375-386
-
-
Ieda, M.1
Fu, J.-D.2
Delgado-Olguin, P.3
Vedantham, V.4
Hayashi, Y.5
Bruneau, B.G.6
Srivastava, D.7
-
40
-
-
78951494319
-
Defining genetic factors that modulate intergenerational CAG repeat instability in Drosophila melanogaster
-
Jung J, van Jaarsweld MTM, Shieh S-Y, Xu K, Bonini NM. 2010. Defining genetic factors that modulate intergenerational CAG repeat instability in Drosophila melanogaster. Genetics 187:61-71.
-
(2010)
Genetics
, vol.187
, pp. 61-71
-
-
Jung, J.1
van Jaarsweld, M.T.M.2
Shieh, S.-Y.3
Xu, K.4
Bonini, N.M.5
-
41
-
-
0030982227
-
A sequence conserved in vertebrate Hox gene introns functions as an enhancer regulated by posterior homeotic genes in Drosophila imaginal discs
-
Keegan LP, Haerry TE, Crotty DA, Packer AI, Wolgemuth DJ, Gehring WJ. 1997. A sequence conserved in vertebrate Hox gene introns functions as an enhancer regulated by posterior homeotic genes in Drosophila imaginal discs. Mech Dev 63: 145-157.
-
(1997)
Mech Dev
, vol.63
, pp. 145-157
-
-
Keegan, L.P.1
Haerry, T.E.2
Crotty, D.A.3
Packer, A.I.4
Wolgemuth, D.J.5
Gehring, W.J.6
-
42
-
-
0038444550
-
Gata factor Pannier is required to establish competence for heart progenitor formation
-
Klinedinst S, Bodmer R. 2003. Gata factor Pannier is required to establish competence for heart progenitor formation. Development 130: 3027-3038.
-
(2003)
Development
, vol.130
, pp. 3027-3038
-
-
Klinedinst, S.1
Bodmer, R.2
-
43
-
-
0023764031
-
Molecular cloning and characterization of human cardiac alpha- and beta-form myosin heavy chain complementary DNA clones. Regulation of expression during development and pressure overload in human atrium
-
Kurabayashi M, Tsuchimochi H, Komuro I, Takaku F, Yazaki Y. 1988. Molecular cloning and characterization of human cardiac alpha- and beta-form myosin heavy chain complementary DNA clones. Regulation of expression during development and pressure overload in human atrium. J Clin Invest 82: 524-531.
-
(1988)
J Clin Invest
, vol.82
, pp. 524-531
-
-
Kurabayashi, M.1
Tsuchimochi, H.2
Komuro, I.3
Takaku, F.4
Yazaki, Y.5
-
44
-
-
0031844382
-
The cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates atrial natriuretic factor gene expression
-
Lee Y, Shioi T, Kasahara H, Jobe S, Wiese R, Markham B, Izumo S. 1998. The cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates atrial natriuretic factor gene expression. Mol Cell Biol 18: 3120-3129.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 3120-3129
-
-
Lee, Y.1
Shioi, T.2
Kasahara, H.3
Jobe, S.4
Wiese, R.5
Markham, B.6
Izumo, S.7
-
45
-
-
0031859828
-
Equivalence of the fly orthodenticle gene and the human OTX genes in embryonic brain development of Drosophila
-
Leuzinger S, Hirth F, Gerlich D, Acampora D, Simeone A, Gehring WJ, Finkelstein R, Furukubo-Tokunaga K, Reichert H. 1998. Equivalence of the fly orthodenticle gene and the human OTX genes in embryonic brain development of Drosophila. Development (Cambridge, England) 125: 1703-1710.
-
(1998)
Development (Cambridge, England)
, vol.125
, pp. 1703-1710
-
-
Leuzinger, S.1
Hirth, F.2
Gerlich, D.3
Acampora, D.4
Simeone, A.5
Gehring, W.J.6
Finkelstein, R.7
Furukubo-Tokunaga, K.8
Reichert, H.9
-
46
-
-
1842413728
-
Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family
-
Li Q, Newbury-Ecob R, Terrett J, Wilson D, Curtis A, Yi C, Gebuhr T, Bullen P, Robson S, Strachan T, Bonnet D, Lyonnet S, Young I, Raeburn J, Buckler A, Law D, Brook J. 1997. Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family. Nat Genet 15: 21-29.
-
(1997)
Nat Genet
, vol.15
, pp. 21-29
-
-
Li, Q.1
Newbury-Ecob, R.2
Terrett, J.3
Wilson, D.4
Curtis, A.5
Yi, C.6
Gebuhr, T.7
Bullen, P.8
Robson, S.9
Strachan, T.10
Bonnet, D.11
Lyonnet, S.12
Young, I.13
Raeburn, J.14
Buckler, A.15
Law, D.16
Brook, J.17
-
47
-
-
0033377879
-
A sequence motif distinct from Hox binding sites controls the specificity of a Hox response element
-
Li X, Veraksa A, McGinnis W. 1999. A sequence motif distinct from Hox binding sites controls the specificity of a Hox response element. Development 126: 5581-5589.
-
(1999)
Development
, vol.126
, pp. 5581-5589
-
-
Li, X.1
Veraksa, A.2
McGinnis, W.3
-
48
-
-
0032937224
-
Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer
-
Lien CL, Wu C, Mercer B, Webb R, Richardson JA, Olson EN. 1999. Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer. Development (Cambridge, England) 126: 75-84.
-
(1999)
Development (Cambridge, England)
, vol.126
, pp. 75-84
-
-
Lien, C.L.1
Wu, C.2
Mercer, B.3
Webb, R.4
Richardson, J.A.5
Olson, E.N.6
-
49
-
-
0030601346
-
Functional analysis of Drosophila and mammalian cut proteins in files
-
Ludlow C, Choy R, Blochlinger K. 1996. Functional analysis of Drosophila and mammalian cut proteins in files. Dev Biol 178: 149-159.
-
(1996)
Dev Biol
, vol.178
, pp. 149-159
-
-
Ludlow, C.1
Choy, R.2
Blochlinger, K.3
-
50
-
-
0026783241
-
Human amyloid precursor protein ameliorates behavioral deficit of flies deleted for Appl gene
-
Luo L, Tully T, White K. 1992. Human amyloid precursor protein ameliorates behavioral deficit of flies deleted for Appl gene. Neuron 9: 595-605.
-
(1992)
Neuron
, vol.9
, pp. 595-605
-
-
Luo, L.1
Tully, T.2
White, K.3
-
51
-
-
58649091740
-
Interaction of Gata4 and Gata6 with Tbx5 is critical for normal cardiac development
-
Maitra M, Schluterman MK, Nichols HA, Richardson JA, Lo CW, Srivastava D, Garg V. 2009. Interaction of Gata4 and Gata6 with Tbx5 is critical for normal cardiac development. Dev Biol 326: 368-377.
-
(2009)
Dev Biol
, vol.326
, pp. 368-377
-
-
Maitra, M.1
Schluterman, M.K.2
Nichols, H.A.3
Richardson, J.A.4
Lo, C.W.5
Srivastava, D.6
Garg, V.7
-
52
-
-
0026703840
-
A human HOX4B regulatory element provides head-specific expression in Drosophila embryos
-
Malicki J, Cianetti LC, Peschle C, McGinnis W. 1992. A human HOX4B regulatory element provides head-specific expression in Drosophila embryos. Nature 358: 345-347.
-
(1992)
Nature
, vol.358
, pp. 345-347
-
-
Malicki, J.1
Cianetti, L.C.2
Peschle, C.3
McGinnis, W.4
-
53
-
-
0028283186
-
Transcription factor GATA-4 regulates cardiac muscle-specific expression of the alpha-myosin heavy-chain gene
-
Molkentin J, Kalvakolanu D, Markham B. 1994. Transcription factor GATA-4 regulates cardiac muscle-specific expression of the alpha-myosin heavy-chain gene. Mol Cell Biol 14: 4947-4957.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 4947-4957
-
-
Molkentin, J.1
Kalvakolanu, D.2
Markham, B.3
-
54
-
-
2442648749
-
TBX5 mutations and congenital heart disease: Holt-Oram syndrome revealed
-
Mori A, Bruneau B. 2004. TBX5 mutations and congenital heart disease: Holt-Oram syndrome revealed. Curr Opin Cardiol 19: 211-215.
-
(2004)
Curr Opin Cardiol
, vol.19
, pp. 211-215
-
-
Mori, A.1
Bruneau, B.2
-
55
-
-
0032584150
-
Developmental rescue of Drosophila cephalic defects by the human Otx genes
-
Nagao T, Leuzinger S, Acampora D, Simeone A, Finkelstein R, Reichert H, Furukubo-Tokunaga K. 1998. Developmental rescue of Drosophila cephalic defects by the human Otx genes. Proc Natl Acad Sci USA 95: 3737-3742.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 3737-3742
-
-
Nagao, T.1
Leuzinger, S.2
Acampora, D.3
Simeone, A.4
Finkelstein, R.5
Reichert, H.6
Furukubo-Tokunaga, K.7
-
56
-
-
37349129016
-
Genetic insights into normal and abnormal heart development
-
Nemer M. 2008. Genetic insights into normal and abnormal heart development. Cardiovasc Pathol 17: 48-54.
-
(2008)
Cardiovasc Pathol
, vol.17
, pp. 48-54
-
-
Nemer, M.1
-
57
-
-
33749361499
-
Gene regulatory networks in the evolution and development of the heart
-
Olson E. 2006. Gene regulatory networks in the evolution and development of the heart. Science 313: 1922-1927.
-
(2006)
Science
, vol.313
, pp. 1922-1927
-
-
Olson, E.1
-
58
-
-
13144257684
-
Differential rescue of visceral and cardiac defects in Drosophila by vertebrate tinman-related genes
-
Park M, Lewis C, Turbay D, Chung A, Chen J, Evans S, Breitbart R, Fishman M, Izumo S, Bodmer R. 1998. Differential rescue of visceral and cardiac defects in Drosophila by vertebrate tinman-related genes. Proc Natl Acad Sci USA 95: 9366-9371.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 9366-9371
-
-
Park, M.1
Lewis, C.2
Turbay, D.3
Chung, A.4
Chen, J.5
Evans, S.6
Breitbart, R.7
Fishman, M.8
Izumo, S.9
Bodmer, R.10
-
59
-
-
0029055810
-
Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx
-
Pöpperl H, Bienz M, Studer M, Chan SK, Aparicio S, Brenner S, Mann RS, Krumlauf R. 1995. Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx. Cell 81: 1031-1042.
-
(1995)
Cell
, vol.81
, pp. 1031-1042
-
-
Pöpperl, H.1
Bienz, M.2
Studer, M.3
Chan, S.K.4
Aparicio, S.5
Brenner, S.6
Mann, R.S.7
Krumlauf, R.8
-
60
-
-
14544291982
-
Neuromancer Tbx20-related genes (H15/midline) promote cell fate specification and morphogenesis of the Drosophila heart
-
Qian L, Liu J, Bodmer R. 2005. Neuromancer Tbx20-related genes (H15/midline) promote cell fate specification and morphogenesis of the Drosophila heart. Dev Biol 279: 509-524.
-
(2005)
Dev Biol
, vol.279
, pp. 509-524
-
-
Qian, L.1
Liu, J.2
Bodmer, R.3
-
61
-
-
0025736036
-
The bx region enhancer, a distant cis-control element of the Drosophila Ubx gene and its regulation by hunchback and other segmentation genes
-
Qian S, Capovilla M, Pirrotta V. 1991. The bx region enhancer, a distant cis-control element of the Drosophila Ubx gene and its regulation by hunchback and other segmentation genes. EMBO J 10:1415-1425.
-
(1991)
EMBO J
, vol.10
, pp. 1415-1425
-
-
Qian, S.1
Capovilla, M.2
Pirrotta, V.3
-
62
-
-
0027258138
-
Molecular mechanisms of pattern formation by the BRE enhancer of the Ubx gene
-
Qian S, Capovilla M, Pirrotta V. 1993. Molecular mechanisms of pattern formation by the BRE enhancer of the Ubx gene. EMBO J 10:3865-3877.
-
(1993)
EMBO J
, vol.10
, pp. 3865-3877
-
-
Qian, S.1
Capovilla, M.2
Pirrotta, V.3
-
63
-
-
0027333320
-
pannier, a negative regulator of achaete and scute in Drosophila, encodes a zinc finger protein with homology to the vertebrate transcription factor GATA-1
-
Ramain P, Heitzler P, Haenlin M, Simpson P. 1993. pannier, a negative regulator of achaete and scute in Drosophila, encodes a zinc finger protein with homology to the vertebrate transcription factor GATA-1. Development (Cambridge, England) 119: 1277-1291.
-
(1993)
Development (Cambridge, England)
, vol.119
, pp. 1277-1291
-
-
Ramain, P.1
Heitzler, P.2
Haenlin, M.3
Simpson, P.4
-
64
-
-
0031685432
-
Divergent roles for NK-2 class homeobox genes in cardiogenesis in flies and mice
-
Ranganayakulu G, Elliott DA, Harvey RP, Olson EN. 1998. Divergent roles for NK-2 class homeobox genes in cardiogenesis in flies and mice. Development (Cambridge, England) 125: 3037-3048.
-
(1998)
Development (Cambridge, England)
, vol.125
, pp. 3037-3048
-
-
Ranganayakulu, G.1
Elliott, D.A.2
Harvey, R.P.3
Olson, E.N.4
-
65
-
-
28844432418
-
The Dorsocross T-box genes are key components of the regulatory network controlling early cardiogenesis in Drosophila
-
Reim I, Frasch M. 2005. The Dorsocross T-box genes are key components of the regulatory network controlling early cardiogenesis in Drosophila. Development 132: 4911-4925.
-
(2005)
Development
, vol.132
, pp. 4911-4925
-
-
Reim, I.1
Frasch, M.2
-
66
-
-
77954759123
-
Genetic and genomic dissection of cardiogenesis in the Drosophila model
-
Reim I, Frasch M. 2010. Genetic and genomic dissection of cardiogenesis in the Drosophila model. Pediatr Cardiol 31: 325-334.
-
(2010)
Pediatr Cardiol
, vol.31
, pp. 325-334
-
-
Reim, I.1
Frasch, M.2
-
67
-
-
0041669539
-
The T-box-encoding Dorsocross genes function in amnioserosa development and the patterning of the dorsolateral germ band downstream of Dpp
-
Reim I, Lee H, Frasch M. 2003. The T-box-encoding Dorsocross genes function in amnioserosa development and the patterning of the dorsolateral germ band downstream of Dpp. Development 130: 3187-3204.
-
(2003)
Development
, vol.130
, pp. 3187-3204
-
-
Reim, I.1
Lee, H.2
Frasch, M.3
-
68
-
-
23144464213
-
Tbx20-related genes, mid and H15, are required for tinman expression, proper patterning, and normal differentiation of cardioblasts in Drosophila
-
Reim I, Mohler J, Frasch M. 2005. Tbx20-related genes, mid and H15, are required for tinman expression, proper patterning, and normal differentiation of cardioblasts in Drosophila. Mech Dev 122: 1056-1069.
-
(2005)
Mech Dev
, vol.122
, pp. 1056-1069
-
-
Reim, I.1
Mohler, J.2
Frasch, M.3
-
69
-
-
66549083305
-
NKX2-5 regulates the expression of beta-catenin and GATA4 in ventricular myocytes
-
Riazi AM, Takeuchi JK, Hornberger LK, Zaidi SH, Amini F, Coles J, Bruneau BG, Van Arsdell GS. 2009. NKX2-5 regulates the expression of beta-catenin and GATA4 in ventricular myocytes. PLoS ONE 4: e5698.
-
(2009)
PLoS ONE
, vol.4
-
-
Riazi, A.M.1
Takeuchi, J.K.2
Hornberger, L.K.3
Zaidi, S.H.4
Amini, F.5
Coles, J.6
Bruneau, B.G.7
Van Arsdell, G.S.8
-
70
-
-
33846849311
-
The NK homeodomain transcription factor Tinman is a direct activator of seven-up in the Drosophila dorsal vessel
-
Ryan KM, Hendren JD, Helander LA, Cripps RM. 2007. The NK homeodomain transcription factor Tinman is a direct activator of seven-up in the Drosophila dorsal vessel. Dev Biol 302: 694-702.
-
(2007)
Dev Biol
, vol.302
, pp. 694-702
-
-
Ryan, K.M.1
Hendren, J.D.2
Helander, L.A.3
Cripps, R.M.4
-
71
-
-
0033404512
-
Regulation of Hox target genes by a DNA bound Homothorax/Hox/Extradenticle complex
-
Ryoo H, Marty T, Casares F, Affolter M, Mann R. 1999. Regulation of Hox target genes by a DNA bound Homothorax/Hox/Extradenticle complex. Development 126: 5137-5148.
-
(1999)
Development
, vol.126
, pp. 5137-5148
-
-
Ryoo, H.1
Marty, T.2
Casares, F.3
Affolter, M.4
Mann, R.5
-
72
-
-
0032479573
-
Congenital heart disease caused by mutations in the transcription factor NKX2-5
-
Schott J, Benson D, Basson C, Pease W, Silberbach G, Moak J, Maron B, Seidman C, Seidman J. 1998. Congenital heart disease caused by mutations in the transcription factor NKX2-5. Science 281: 108-111.
-
(1998)
Science
, vol.281
, pp. 108-111
-
-
Schott, J.1
Benson, D.2
Basson, C.3
Pease, W.4
Silberbach, G.5
Moak, J.6
Maron, B.7
Seidman, C.8
Seidman, J.9
-
73
-
-
33344456214
-
Dynamics of heart differentiation, visualized utilizing heart enhancer elements of the Drosophila melanogaster bHLH transcription factor Hand
-
Sellin J, Albrecht S, Kolsch V, Paululat A. 2006. Dynamics of heart differentiation, visualized utilizing heart enhancer elements of the Drosophila melanogaster bHLH transcription factor Hand. Gene Expr Patterns 6: 360-375.
-
(2006)
Gene Expr Patterns
, vol.6
, pp. 360-375
-
-
Sellin, J.1
Albrecht, S.2
Kolsch, V.3
Paululat, A.4
-
74
-
-
33748621746
-
Making or breaking the heart: from lineage determination to morphogenesis
-
Srivastava D. 2006. Making or breaking the heart: from lineage determination to morphogenesis. Cell 126: 1037-1048.
-
(2006)
Cell
, vol.126
, pp. 1037-1048
-
-
Srivastava, D.1
-
75
-
-
66649127942
-
Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors
-
Takeuchi JK, Bruneau BG. 2009. Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors. Nature 459: 708-711.
-
(2009)
Nature
, vol.459
, pp. 708-711
-
-
Takeuchi, J.K.1
Bruneau, B.G.2
-
76
-
-
0026492021
-
Homeotic genes of the Bithorax complex repress limb development in the abdomen of the Drosophila embryo through the target gene Distal-less
-
Vachon G, Cohen B, Pfeifle C, McGuffin M, Botas J, Cohen S. 1992. Homeotic genes of the Bithorax complex repress limb development in the abdomen of the Drosophila embryo through the target gene Distal-less. Cell 71: 437-450.
-
(1992)
Cell
, vol.71
, pp. 437-450
-
-
Vachon, G.1
Cohen, B.2
Pfeifle, C.3
McGuffin, M.4
Botas, J.5
Cohen, S.6
-
77
-
-
0026287693
-
Identification of target genes of the homeotic gene Antennapedia by enhancer detection
-
Wagner-Bernholz JT, Wilson C, Gibson G, Schuh R, Gehring WJ. 1991. Identification of target genes of the homeotic gene Antennapedia by enhancer detection. Genes Dev 5: 2467-2480.
-
(1991)
Genes Dev
, vol.5
, pp. 2467-2480
-
-
Wagner-Bernholz, J.T.1
Wilson, C.2
Gibson, G.3
Schuh, R.4
Gehring, W.J.5
-
78
-
-
0032942213
-
Regulation of Pax6 expression is conserved between mice and flies
-
Xu PX, Zhang X, Heaney S, Yoon A, Michelson AM, Maas RL. 1999. Regulation of Pax6 expression is conserved between mice and flies. Development (Cambridge, England) 126: 383-395.
-
(1999)
Development (Cambridge, England)
, vol.126
, pp. 383-395
-
-
Xu, P.X.1
Zhang, X.2
Heaney, S.3
Yoon, A.4
Michelson, A.M.5
Maas, R.L.6
-
79
-
-
0031805714
-
Regulation and function of tinman during dorsal mesoderm induction and heart specification in Drosophila
-
Yin Z, Frasch M. 1998. Regulation and function of tinman during dorsal mesoderm induction and heart specification in Drosophila. Dev Genet 22: 187-200.
-
(1998)
Dev Genet
, vol.22
, pp. 187-200
-
-
Yin, Z.1
Frasch, M.2
-
80
-
-
0031468348
-
Regulation of the twist target gene tinman by modular cis-regulatory elements during early mesoderm development
-
Yin Z, Xu X, Frasch M. 1997. Regulation of the twist target gene tinman by modular cis-regulatory elements during early mesoderm development. Development 124: 4971-4982.
-
(1997)
Development
, vol.124
, pp. 4971-4982
-
-
Yin, Z.1
Xu, X.2
Frasch, M.3
-
81
-
-
0030959948
-
The held out wings (how) Drosophila gene encodes a putative RNA-binding protein involved in the control of muscular and cardiac activity
-
Zaffran S, Astier M, Gratecos D, Sémériva M. 1997. The held out wings (how) Drosophila gene encodes a putative RNA-binding protein involved in the control of muscular and cardiac activity. Development (Cambridge, England) 124: 2087-2098.
-
(1997)
Development (Cambridge, England)
, vol.124
, pp. 2087-2098
-
-
Zaffran, S.1
Astier, M.2
Gratecos, D.3
Sémériva, M.4
-
82
-
-
33751061126
-
Cardioblast-intrinsic Tinman activity controls proper diversification and differentiation of myocardial cells in Drosophila
-
Zaffran S, Reim I, Qian L, Lo P, Bodmer R, Frasch M. 2006. Cardioblast-intrinsic Tinman activity controls proper diversification and differentiation of myocardial cells in Drosophila. Development 133: 4073-4083.
-
(2006)
Development
, vol.133
, pp. 4073-4083
-
-
Zaffran, S.1
Reim, I.2
Qian, L.3
Lo, P.4
Bodmer, R.5
Frasch, M.6
-
83
-
-
0034634624
-
Functional analyses of three Csx/Nkx-2.5 mutations that cause human congenital heart disease
-
Zhu W, Shiojima I, Hiroi Y, Zou Y, Akazawa H, Mizukami M, Toko H, Yazaki Y, Nagai R, Komuro I. 2000. Functional analyses of three Csx/Nkx-2.5 mutations that cause human congenital heart disease. J Biol Chem 275: 35291-35296.
-
(2000)
J Biol Chem
, vol.275
, pp. 35291-35296
-
-
Zhu, W.1
Shiojima, I.2
Hiroi, Y.3
Zou, Y.4
Akazawa, H.5
Mizukami, M.6
Toko, H.7
Yazaki, Y.8
Nagai, R.9
Komuro, I.10
|