Endoplasmic reticulum stress-mediated inhibition of NSMase2 elevates plasma membrane cholesterol and attenuates NO production in endothelial cells

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1821, Issue 2, 2012, Pages 313-323

  Chaube, Ruchi ^a   Kallakunta, Vasantha Madhuri ^a   Espey, Michael Graham ^b   McLarty, Ryan ^a   Faccenda, Adam ^a   Ananvoranich, Sirinart ^a   Mutus, Bulent ^a  

^a UNIVERSITY OF WINDSOR   (Canada)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Endothelial dysfunction; ER stress; Neutral sphingomyelinase 2; Nitric oxide; Nitric oxide synthase

Indexed keywords

CHOLESTEROL OXIDASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; PALMITIC ACID; SPHINGOMYELIN PHOSPHODIESTERASE; TUNICAMYCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATTENUATION; CELL MEMBRANE; CELL THERAPY; CELL VIABILITY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME ACTIVITY; EPIFLUORESCENCE MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING;

ANIMALS; BIOLOGICAL MARKERS; CATTLE; CELL MEMBRANE; CHOLESTEROL; ENDOPLASMIC RETICULUM STRESS; ENDOTHELIAL CELLS; GENE KNOCKDOWN TECHNIQUES; HEAT-SHOCK PROTEINS; IMMUNOPRECIPITATION; INTRACELLULAR SPACE; MODELS, BIOLOGICAL; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHORYLATION; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES; SPHINGOMYELIN PHOSPHODIESTERASE;

EID: 83655164011     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2011.10.015     Document Type: Article

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