Ubiquitylation of MHC class I by the K3 viral protein signals internalization and TSG101-dependent degradation

EMBO Journal

Volumn 21, Issue 10, 2002, Pages 2418-2429

  Hewitt, Eric W ^a   Duncan, Lidia ^a   Mufti, Dina ^a   Baker, John ^b   Stevenson, Philip G ^c   Lehner, Paul J ^d  

^a DIVISION OF REPRODUCTIVE BIOLOGY   (United States)

^b UNIVERSITY OF LONDON   (United Kingdom)

^c RESEARCH AND DEVELOPMENT   (Australia)

^d ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

HHV8 K3; MHC class I; TSG101; Ubiquitin; Viral evasion

Indexed keywords

GENE PRODUCT; HOMEODOMAIN PROTEIN; K3 PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; TUMOR SUSCEPTIBILITY GENE 101 PROTEIN; UNCLASSIFIED DRUG; VIRUS ENZYME; VIRUS PROTEIN; VIRUS RNA;

AMINO TERMINAL SEQUENCE; ANTIGEN PRESENTATION; ARTICLE; CELL MEMBRANE; CELL SELECTION; CONTROLLED STUDY; DOWN REGULATION; ENDOCYTOSIS; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; KAPOSI SARCOMA; MAJOR HISTOCOMPATIBILITY COMPLEX; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MODIFICATION; VIRUS GENE;

DNA-BINDING PROTEINS; HELA CELLS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; LEUCINE ZIPPERS; OPEN READING FRAMES; PROTEIN TRANSPORT; RECOMBINANT PROTEINS; TRANSCRIPTION FACTORS; TRANSFECTION; UBIQUITIN; VIRAL PROTEINS; ZINC FINGERS;

HERPESVIRIDAE;

EID: 0037093467     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/21.10.2418     Document Type: Article

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