Concise diverted total synthesis of amphidinolide T1 and T4 from a (12 E)-cycloalkene by selective functionalization of the C12-C13 double bond

Synlett

Volumn , Issue 20, 2011, Pages 3036-3040

  Sun, Lijie ^a   Wu, Dongdong ^b   Wu, Jinlong ^b   Dai, Wei Min ^a,b  

^a HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

alkenes; dihydroxylation; macrocycles; osmium; total synthesis

Indexed keywords

AMPHIDINOLIDE T1; AMPHIDINOLIDE T4; ANTINEOPLASTIC AGENT; CYCLOALKENE; TOLUENE; UNCLASSIFIED DRUG;

ALDOL REACTION; ARTICLE; CANCER CELL; CATALYST; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY TEST; DESILYLATION; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; SILYLATION; SOLVENT EFFECT; STEREOCHEMISTRY;

EID: 82955249040     PISSN: 09365214     EISSN: 14372096     Source Type: Journal    
DOI: 10.1055/s-0031-1289903     Document Type: Article

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