Synthesis at the molecular frontier

Nature

Volumn 460, Issue 7252, 2009, Pages 197-201

  Wender, Paul A ^a   Miller, Benjamin L ^b  

^a STANFORD UNIVERSITY   (United States)

^b UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NATURAL PRODUCT;

CHEMICAL ANALYSIS; CHEMICAL COMPOSITION; MOLECULAR ANALYSIS; REACTION KINETICS;

CHEMICAL REACTION; CHEMICAL STRUCTURE; MOLECULAR BIOLOGY; MOLECULAR EVOLUTION; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; REVIEW; SYNTHESIS;

ANIMALS; BIOLOGICAL PRODUCTS; BIOMIMETIC MATERIALS; BRYOSTATINS; CHEMISTRY, ORGANIC; DRUG DESIGN; HUMANS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 67650527061     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/460197a     Document Type: Review

References (50)

1. Seebach, D. Angew. Chem. Int. Edn 29, 1320-1367 (1990).
2. Cornforth, J. W. Aust. J. Chem. 46, 157-170 (1993).
3. Wender, P. A. & Miller, B. L. in Connectivity Analysis and Multibond-forming Processes in Organic Synthesis: Theory and Applications ( ed. Hudlicky, T.) 27-66 (JAI Press, 1993).
4. Tietze, L. F. Domino Reactions in Organic Synthesis (Wiley-VCH, 2006).
5. Nicolaou, K. C. Tetrahedron 59, 6683-6738 (2003).
6. Wilson, R. M. & Danishefsky, S. J. J. Org. Chem. 71, 8329-8351 (2006).
7. Horvath, I. & Anastas, P. T. Chem. Rev. 107, 2169-2173 (2007).
8. Corey, E. J., Czakó, B. & Kürti, L. Molecules and Medicine (John Wiley, 2007).
9. Hudlicky, T. & Reed, J. W. The Way of Synthesis: Evolution of Design and Methods for Natural Products ( Wiley-VCH, 2007).
10. Trost, B. M. Science 254, 1471-1477 (1991).
11. Maimone, T. J. & Baran, P. S. Nature Chem. Biol. 3, 396-407 (2007).
12. Koshino, M., Solin, N., Tanaka, T., Isobe, H. & Nakamura, E. Nature Nanotechnol. 3, 595-597 (2008).
13. Sudek, S. et al. J. Nat. Prod. 70, 67-74 (2007).
14. Wender, P. A. et al. in Drug Discovery Research (ed. Huang, Z.) 127-162 (John Wiley, 2007).
15. Sun, M.-K. & Alkon, D. L. Eur. J. Pharmacol. 584, 328-337 (2008).
16. Kingston, D. G. & Newman, D. J. Curr. Opin. Drug Discov. Dev. 10, 130-144 (2007).
17. Newman, D. J. & Cragg, G. M. J. Nat. Prod. 70, 461-477 (2007).
18. Wender, P. A., Kee, J. M. & Warrington, J. M. Science 320, 649-652 (2008).
19. Johnson, H. E., Banack, S. A. & Cox, P. A. J. Nat. Prod. 71, 2041-2044 (2008).
20. LaVan, D. A. & Cha, J. N. Proc. Natl Acad. Sci. USA 103, 5251-5255 (2006).
21. Hampp, N. Chem. Rev. 100, 1755-1776 (2000).
22. Greenbaum, E. et al. Tech. Dig. Int. Electron. Device Meet. 496-498 (2002).
23. Wender, P. A. et al. Pure Appl. Chem. 74, 25-31 (2002).
24. Hinman, A. & Du Bois, J. J. Am. Chem. Soc. 125, 11510-11511 (2003).
25. Chen, M. S. & White, M. C. Science 318, 783-787 (2007).
26. Chen, H., Schlecht, S., Semple, T. C. & Hartwig, J. F. Science 287, 1995-1997 (2000).
27. Wender, P. A., Verma, V. A., Paxton, T. J. & Pillow, T. H. Acc. Chem. Res. 41, 40-49 (2008).
28. Robinson, R. J. Chem. Soc. 762-768 (1917).
29. Chanon, M., Barone, R., Baralotto, C., Julliard, M. & Hendrikson, J. B. Synthesis 1998, 1559-1583 (1998).
30. Wender, P. A. (ed.) Chem. Rev. 96, 1-600 (1996).
31. Yoder, R. A. & Johnston, J. N. Chem. Rev. 105, 4730-4756 (2005).
32. Vilotijevic, I. & Jamison, T. F. Science 317, 1189-1192 (2007).
33. Curran, D. P. & Kuo, S.-C. Tetrahedron 43, 5653-5661 (1987).
34. Padwa, A. & Bur, S. K. Tetrahedron 63, 5341-5378 (2007).
35. Nicewicz, D. A., Satterfield, A. D., Schmitt, D. C. & Johnson, J. S. J. Am. Chem. Soc. 130, 17281-17283 (2008).
36. Reppe, W. et al. Liebigs Ann. Chem. 560, 1-92 (1948).
37. Chappell, D. & Russell, A. T. Org. Biomol. Chem. 4, 4409-4430 (2006).
38. Das, A. & Khosla, C. Acc. Chem. Res. 42, 631-639 (2009).
39. Hale, K. J., Hummersone, M. G., Manaviazar, S. & Frigerio, M. Nat. Prod. Rep. 19, 413-453 (2002).
40. Wender, P. A., DeChristopher, B. A. & Schrier, A. J. E. J. Am. Chem. Soc. 130, 6658-6659 (2008).
41. Wulff, J. E., Herzon, S. B., Siegrist, R. & Myers, A. G. J. Am. Chem. Soc. 129, 4898-4899 (2007).
42. Towle, M. J. et al. Cancer Res. 61, 1013-1021 (2001).
43. Szpilman, A. M., Manthorpe, J. M. & Carreira, E. M. Angew. Chem. Int. Edn 47, 4339-4342 (2008).
44. Dubikovskaya, E. A. et al. Proc. Natl Acad. Sci. USA 105, 12128-12133 (2008).
45. Krueger, A. T. & Kool, E. T. Chem. Biol. 16, 242-248 (2009).
46. Schreiber, S. L. Science 287, 1964-1969 (2000).
47. Thomas, G. L. et al. Angew. Chem. Int. Edn 47, 2808-2812 (2008).
48. Corbett, P. T. et al. Chem. Rev. 106, 3652-3711 (2006).
49. McNaughton, B. R., Gareiss, P. C. & Miller, B. L. J. Am. Chem. Soc. 129, 11306-11307 (2007).
50. Gareiss, P. C. et al. J. Am. Chem. Soc. 130, 16254-16261 (2008).