B-Ring-Modified isoCombretastatin A-4 Analogues Endowed with Interesting Anticancer Activities

ChemMedChem

Volumn 6, Issue 12, 2011, Pages 2179-2191

  Hamze, Abdallah ^a   Rasolofonjatovo, Evelia ^a   Provot, Olivier ^a   Mousset, Céline ^a   Veau, Damien ^a   Rodrigo, Jordi ^a   Bignon, Jérôme ^b   Liu, Jian Miao ^b   Wdzieczak Bakala, Joanna ^b   Thoret, Sylviane ^b   Dubois, Joëlle ^b   Brion, Jean Daniel ^a   Alami, Mouad ^a  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b CNRS   (France)

Author keywords

Antitumor agents; Apoptosis; CombretastatinA 4; Cytotoxicity; Inhibitors; Tubulin

Indexed keywords

3 [2 METHOXY 5 [1 (3,4,5 TRIMETHOXYPHENYL)VINYL]PHENYL] PROP 2 EN 1 OL; 3 [2 METHOXY 5 [1 (3,4,5 TRIMETHOXYPHENYL)VINYL]PHENYL] PROP 2 YN 1 OL; ANTINEOPLASTIC AGENT; COLCHICINE; ISOCOMBRESTATIN A 4 DERIVATIVE; TUBULIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL STRAIN H1299; CELL STRAIN HCT116; CELL STRAIN K562; CELL STRAIN MDA MB231; CONTROLLED STUDY; DRUG POTENCY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MOLECULAR DOCKING; POLYMERIZATION; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANISOLES; ANTINEOPLASTIC AGENTS; BINDING SITES; CELL LINE, TUMOR; CELL SURVIVAL; COMPUTER SIMULATION; HUMANS; NEOPLASMS; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP; STYRENES; TUBULIN; TUBULIN MODULATORS;

EID: 82955197351     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201100325     Document Type: Article

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