Novel combretastatin analogues effective against murine solid tumors: Design and structure-activity relationships

Journal of Medicinal Chemistry

Volumn 41, Issue 16, 1998, Pages 3022-3032

  Ohsumi, Koji ^a   Nakagawa, Ryusuke ^a   Fukuda, Yumiko ^a   Hatanaka, Toshihiro ^a   Morinaga, Yoshihiro ^a   Nihei, Yukio ^a   Ohishi, Kazuo ^a   Suga, Yasuyo ^a   Akiyama, Yukio ^a   Tsuji, Takashi ^a  

^a AJINOMOTO CO INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHOXY 5 [2 (3,4,5 TRIMETHOXYPHENYL)VINYL]PHENYLAMINE; 2 METHYL 5 [2 (3,4,5 TRIMETHOXYPHENYL)VINYL]PHENYLAMINE; 3 (3 AMINO 4 METHOXYPHENYL) 2 (3,4,5 TRIMETHOXYPHENYL)ACRYLONITRILE; COMBRETASTATIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER GRAFT; CANCER MODEL; COLON ADENOCARCINOMA; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; INTRAVENOUS DRUG ADMINISTRATION; MOUSE; NONHUMAN; SOLID TUMOR; STRUCTURE ACTIVITY RELATION;

ACRYLONITRILE; ADENOCARCINOMA; ANILINE COMPOUNDS; ANIMALS; ANISOLES; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BIOPOLYMERS; CELL SURVIVAL; COLONIC NEOPLASMS; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MICE; NEOPLASM TRANSPLANTATION; SOLUBILITY; STILBENES; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSPLANTATION, HETEROLOGOUS; TUBULIN; TUMOR CELLS, CULTURED;

EID: 15144356733     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980101w     Document Type: Article

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