Activity of the vascular targeting agent combretastatin A-4 disodium phosphate in a xenograft model of AIDS-associated Kaposi's sarcoma

Acta Oncologica

Volumn 41, Issue 1, 2002, Pages 98-105

  Rojiani, Amyn M ^a   Li, Lingyun ^a   Rise, Leroy ^a   Siemann, Dietmar W ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DISEASES; ELECTRON MICROSCOPY; PATIENT TREATMENT;

PATHOGENESIS;

SODIUM COMPOUNDS;

COMBRETASTATIN A4;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; DRUG EFFECT; DRUG MECHANISM; DRUG SCREENING; DRUG USE; HUMAN; HUMAN CELL; KAPOSI SARCOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BENZIMIDAZOLES; BLOOD VESSELS; CELL DIVISION; CELLS, CULTURED; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOENZYME TECHNIQUES; MICE; MICE, NUDE; NEOVASCULARIZATION, PATHOLOGIC; SARCOMA, EXPERIMENTAL; SARCOMA, KAPOSI; STILBENES; TUMOR MARKERS, BIOLOGICAL;

EID: 0036221310     PISSN: 0284186X     EISSN: None     Source Type: Journal    
DOI: 10.1080/028418602317314136     Document Type: Article

References (30)

1. Kaposi's sarcoma: Advances in tumor biology and pharmacotherapy
2. The enigmas of Kaposi's sarcoma
3. AIDS-associated Kaposi's sarcoma
4. Inhibition of development of Kaposi's sarcoma-related lesions by a bacterial cell wall complex
5. Vascular endothelial growth factor regulates angiogenesis and vascular permeability in Kaposi's sarcoma
6. Fumagillin analog in the treatment of Kaposi's sarcoma: A phase I AIDS clinical trial group study
7. Kaposi's sarcoma. New treatment modalities
8. Activity of thalidomide in AIDS-related Kaposi's sarcoma and correlation with HHV8 titre
9. Activity of thalidomide in AIDS-related Kaposi's sarcoma
10. The current status of targeting tumour vasculature as a means of cancer therapy - An overview
11. Angiogenesis, neovascular proliferation and vascular pathophysiology as targets for cancer therapy
12. Anticancer strategies involving the vasculature: Vascular targeting and the inhibition of angiogenesis
13. Anti-vascular approaches to solid tumor therapy: Evaluation of vinblastine and flavone acetic acid
14. Blood flow failure as a major determinant in the antitumor action of flavone acetic acid
15. Inhibition of growth of colon 38 adenocarcinoma by vinblastine and colchicine. Evidence for a vascular mechanism
16. Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4
17. Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature
18. In vivo and in vitro evaluation of combretastatin A-4 and its sodium phosphate prodrug
19. The effect of combretastatin A-4 disodium phosphate in a C3H mouse mammary carcinoma and a variety of murine spontaneous tumours
20. Propagation and properties of Kaposi's sarcoma-derived cell lines obtained from patients with AIDS: Similarity of cultured cells to smooth muscle cells
21. Establishment and characterization of two new Kaposi's sarcoma cell cultures from an AIDS and a non-AIDS patient
22. Phenotype and proliferation characteristics of cultured spindle-shaped cells obtained from normal human skin and lesions of dermatofibroma, Kaposi's sarcoma, and dermatofibrosarcoma protuberans: A comparison with fibroblast and endothelial cells of the dermis
23. Characterization of a human Kaposi's sarcoma cell line that induces angiogenic tumors in animals
24. Isolation and characterization of an immortal neoplastic cell line (KSY-1) from AIDS-associated Kaposi's sarcoma
25. Validation of the fluorescent dye Hoechst 33342 as a vascular space marker in tumours
26. Area and volume measurements by random sampling methods
27. Targeting the tumor vasculature with combretastatin A-4 disodium phosphate: Effects on radiation therapy
28. Antiangiogenesis drugs target specific cancers, mechanisms
29. Preclinical evaluations of therapies combining the vascular targeting agent combretastatin A-4 disodium phosphate and conventional anticancer therapies in the treatment of Kaposi's sarcoma
30. Targeting tumor blood vessels: An adjuvant strategy for radiation therapy