Inhibition of U6 snRNA transcription by PTEN

OnLine Journal of Biological Sciences

Volumn 10, Issue 3, 2010, Pages 114-125

  Cabarcas, Stephanie ^a,c   Watabe, Kounosuke ^b   Schramm, Laura ^a  

^a ST JOHN'S UNIVERSITY   (United States)

^b SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

BRF2; III transcription; PTEN; RNA polymerase; TFIIIB

Indexed keywords

EID: 79951848196     PISSN: None     EISSN: 16084217     Source Type: Journal    
DOI: 10.3844/ojbsci.2010.114.125     Document Type: Article

References (43)

1. Bandyopadhyay, S., S.K. Pai, S. Hirota, S. Hosobe and T. Tsukada et al., 2004. PTEN up-regulates the tumor metastasis suppressor gene Drg-1 in prostate and breast cancer. Cancer Res., 64: 7655-7660.DOI:10.1158/0008-5472.CAN-04-1623
2. Cabarcas, S., J. Jacob, I. Veras and L. Schramm, 2008. Differential expression of the TFIIIB subunits Brf1 and Brf2 in cancer cells. BMC Mol. Biol., 9:74-74.DOI:10.1186/1471-2199-9-74
3. Chu, W.M., Z. Wang, R.B. Roeder and C.W. Schmid, 1997. RNA polymerase III transcription repressed by Rb through its interactions with TFIIIB and TFIIIC2. J. Biol. Chem., 272: 14755-14761.DOI:10.1074/jbc.272.23.14755
4. Chung, J.H., M.E. Ginn-Pease and C. Eng, 2005. Phosphatase and tensin homologue deleted on chromosome 10 (PTEN) has nuclear localization signal-like sequences for nuclear import mediated by major vault protein. Cancer Res., 65: 4108-4116.DOI:10.1158/0008-5472.CAN-05-0124
5. Das, S., J.E. Dixon and W. Cho, 2003. Membranebinding and activation mechanism of PTEN. PNAS, 100: 7491-7496.DOI:10.1073/pnas.0932835100
6. DelloRusso, C., P.L. Welcsh, W. Wang, R.L. Garcia and M.C. King et al., 2007. Functional characterization of a novel BRCA1-null ovarian cancer cell line in response to ionizing radiation. Mol. Cancer Res., 5: 35-45. PMID:17259345
7. Dillon, R.L., D.E. White and W.J. Muller, 2007. The phosphatidyl inositol 3-kinase signaling network: Implications for human breast cancer. Oncogene, 26: 1338-1345.DOI:10.1038/sj.onc.1210202
8. Felton-Edkins, Z.A., N.S. Kenneth, T.R. Brown, N.L. Daly and N. Gomez-Roman et al., 2003a. Direct regulation of RNA polymerase III transcription by RB, p53 and c-Myc. Cell Cycle, 2: 181-184. PMID:12734418
9. Felton-Edkins, Z.A., J.A. Fairley, E.L. Graham, I.M. Johnston and R.J. White et al., 2003b. The Mitogen-Activated Protein (MAP) kinase ERK induces tRNA synthesis by phosphorylating TFIIIB. EMBO J., 22: 2422-2432.DOI:10.1093/emboj/cdg240
10. Freeman, D.J., A.G. Li, G. Wei, H.H. Li and N. Kertesz et al., 2003. PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase dependent and-independent mechanisms. Cancer Cell, 3: 117-130.DOI:10.1016/S1535-6108(03)00021-7
11. Georgescu, M.M., K.H. Kirsch, T. Akagi, T. Shishido and H. Hanafusa, 1999. The tumor-suppressor activity of PTEN is regulated by its carboxylterminal region. Proc. Natl. Acad. Sci. USA., 96: 10182-10187. PMID:10468583
12. Goodfellow, S.J., E.L. Graham, T. Kantidakis, L. Marshall and B.A. Coppins et al., 2008. Regulation of RNA polymerase III transcription by maf1 in mammalian cells. J. Mol. Biol., 378: 481-491.DOI:10.1016/j.jmb.2008.02.060
13. Hlobilkova, A., P. Guldberg, M. Thullberg, J. Zeuthen and J. Lukas et al., 2000. Cell cycle arrest by the PTEN tumor suppressor is target cell specific and may require protein phosphatase activity. Exp. Cell Res., 256: 571-577.DOI:10.1006/excr.2000.4867
14. Hu, P., K. Samudre, S. Wu, Y. Sun and N. Hernandez, 2004. CK2 phosphorylation of Bdp1 executes cell cycle-specific RNA polymerase III transcription repression. Mol. Cell, 16: 81-92.DOI:10.1016/j.molcel.2004.09.008
15. Jacob, J., S. Cabarcas, I. Veras, N. Zaveri and L. Schramm, 2007. The green tea component EGCG inhibits RNA polymerase III transcription. Biochem. Biophys. Res. Commun., 360: 778-783.DOI:10.1016/j.bbrc.2007.06.114
16. Johnson, S.S., C. Zhang, J. Fromm, I.M. Willis and D.L. Johnson, 2007. Mammalian Maf1 is a negative regulator of transcription by all three nuclear RNA polymerases. Mol. Cell, 26: 367-379.DOI:10.1016/j.molcel.2007.03.021
17. Johnston, I.M., S.J. Allison, J.P. Morton, L. Schramm and P.H. Scott et al., 2002. CK2 forms a stable complex with TFIIIB and activates RNA polymerase III transcription in human cells. Mol. Cell Biol., 22: 3757-3768.DOI:10.1128/MCB.22.11.3757-3768.2002
18. Lee, J.O., H. Yang, M.M. Georgescu, A. Di Cristofano and T. Maehama et al., 1999. Crystal structure of the PTEN tumor suppressor: Implications for its phosphoinositide phosphatase activity and membrane association. Cell, 99: 323-334.DOI:10.1016/S0092-8674(00)81663-3
19. Leresche, A., V.J. Wolf and J.M. Gottesfeld, 1996. Repression of RNA polymerase II and III transcription during M phase of the cell cycle. Exp. Cell Res., 229: 282-288.DOI:10.1006/excr.1996.0373
20. Leslie, N.R. and C.P. Downes, 2004. PTEN function: How normal cells control it and tumor cells lose it. Biochem. J., 382: 1-11. PMID:15193142
21. Lockwood, W.W., R. Chari, B.P. Coe, K.L. Thu and C. Garnis et al., 2010. Integrative genomic analyses identify BRF2 as a novel lineage-specific oncogene in lung squamous cell carcinoma. PLoS Med., 7: e1000315-e1000315.DOI:10.1371/journal.pmed.1000315
22. Met synthesis can drive cell proliferation and oncogenic transformation. Cell, 133: 78-89.DOI:10.1016/j.cell.2008.02.035
23. McMenamin, M.E., P. Soung, S. Perera, I. Kaplan and M. Loda et al., 1999. Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage. Cancer Res., 59: 4291-4296. PMID:10485474
24. Morton, J.P., T. Kantidakis and R.J. White, 2007. RNA polymerase III transcription is repressed in response to the tumor suppressor ARF. Nucleic Acids Res., 35: 3046-3052. DOI:10.1093/nar/gkm208
25. Mossink, M.H., A. van Zon, R.J. Scheper, P. Sonneveld and E.A. Wiemer, 2003. Vaults: A ribonucleoprotein particle involved in drug resistance? Oncogene, 22: 7458-7467.PMID:14576851
26. Odriozola, L., G. Singh, T. Hoang and A.M. Chan, 2007. Regulation of PTEN activity by its carboxylterminal autoinhibitory domain. J. Biol. Chem. 280: 35195-35202.DOI:10.1074/jbc.M611240200
27. Okumura, K., M. Zhao, R.A. DePinho, F.B. Furnari and W.K. Cavenee, 2005. PTEN: A novel antioncogenic function independent of phosphatase activity. Cell Cycle, 4: 540-542. PMID:15753657
28. Planchon, S.M., K.A. Waite and C. Eng, 2008. The nuclear affairs of PTEN. J. Cell Sci., 121: 249-253.DOI:10.1242/jcs.022459
29. Raftopoulou, M., S. Etienne-Manneville, A. Self, S. Nicholls and A. Hall, 2003. Regulation of cell migration by the C2 domain of the tumor suppressor PTEN. Science, 303: 1179-1181.DOI:10.1126/science.1092089
30. Ramaswamy, S., N. Nakamura, F. Vazquez, D.B. Batt and S. Perera et al., 1999. Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway. Proc. Natl. Acad. Sci. USA., 96: 2110-2115. PMID:10051603
31. Reina, J.H., T.N. Azzouz and N. Hernandez, 2006. Maf1, a new player in the regulation of human RNA polymerase III transcription. PLoS ONE, 1: e134-e134.DOI:10.1371/journal.pone.0000134
32. Rollins, J., I. Veras, S. Cabarcas, I. Willis and L. Schramm, 2007. Human Maf1 negatively regulates RNA polymerase III transcription via the TFIIB family members Brf1 and Brf2. Int. J. Biol. Sci., 3: 292-302. PMID:17505538
33. Schramm, L. and N. Hernandez, 2002. Recruitment of RNA polymerase III to its target promoters. Genes Dev., 16: 2593-2620.DOI:10.1101/gad.1018902
34. Simpson, L. and R. Parsons, 2001. PTEN: Life as a tumor suppressor. Exp. Cell Res., 264: 29-41.DOI:10.1006/excr.2000.5130
35. Sutcliffe, J.E., C.A. Cairns, A. McLees, S.J. Allison and K. Tosh et al., 1999. RNA polymerase III transcription factor IIIB is a target for repression by pocket proteins p107 and p130. Mol. Cell Biol., 19: 4255-4261. PMID:10330166
36. Veras, I., E.M. Rosen and L. Schramm, 2009. Inhibition of RNA polymerase III transcription by BRCA1. J. Mol. Biol., 387: 523-531.DOI:10.1016/j.jmb.2009.02.008
37. Waite, K.A. and C. Eng, 2002. Protean PTEN: Form and function. Am. J. Hum. Genet., 70: 829-844.DOI:10.1086/340026
38. Weng, L.P., W.M. Smith, P.L. Dahia, U. Ziebold and E. Gil et al., 1999. PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell death. Cancer Res., 59: 5808-5814. PMID:10582703
39. White, R.J., T.M. Gottlieb, C.S. Downes and S.P. Jackson, 1995. Cell cycle regulation of RNA polymerase III transcription. Mol. Cell Biol., 15: 6653-6662. PMID:8524230
40. White, R.J., 2005. RNA polymerases I and III, growth control and cancer. Nat. Rev. Mol. Cell Biol., 6: 69-78.DOI:10.1038/nrm1551
41. Woiwode, A., S.A.S. Johnson, S. Zhong, C. Zhang and R.G. Roeder et al., 2008. PTEN represses RNA polymerase III-dependent transcription by targeting the TFIIIB complex. Mol. Cell Biol., 28: 4204-4214.DOI:10.1128/MCB.01912-07
42. Yu, Z., N. Fotouhi-Ardakani, L. Wu, M. Maoui and S. Wang et al., 2002. PTEN associates with the vault particles in HeLa cells. J. Biol. Chem., 277: 40247-40252.DOI:10.1074/jbc.M207608200
43. Zhang, C., L. Comai and D.L. Johnson, 2005. PTEN represses RNA polymerase I transcription by disrupting the SL1 complex. Mol. Cell Biol., 25: 6899-6911.DOI:10.1128/MCB.25.16.6899-6911.2005