Nef-mediated lipid raft exclusion of UbcH7 inhibits Cbl activity in T cells to positively regulate signaling

Immunity

Volumn 23, Issue 6, 2005, Pages 621-634

  Simmons, Alison ^a   Gangadharan, Bevin ^b   Hodges, Ashleigh ^a   Sharrocks, Katherine ^a   Prabhakar, Sripadi ^b   García, Angel ^b   Dwek, Raymond ^b   Zitzmann, Nicole ^b   McMichael, Andrew ^a  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CBL PROTEIN; NEF PROTEIN; PROTEIN CDC42; PROTEIN P85; UBCH7 PROTEIN; UBIQUITIN CONJUGATING ENZYME; UNCLASSIFIED DRUG; VAV PROTEIN;

ARTICLE; CD4+ T LYMPHOCYTE; CELL COMMUNICATION; CELLULAR IMMUNITY; COMPLEX FORMATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; LENTIVIRINAE; LIPID RAFT; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; UBIQUITINATION; VIRUS REPLICATION;

BLOTTING, WESTERN; CD4-POSITIVE T-LYMPHOCYTES; CDC42 GTP-BINDING PROTEIN; CELL CYCLE PROTEINS; CELL LINE; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE PRODUCTS, NEF; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HIV; HUMANS; IMMUNOPRECIPITATION; MEMBRANE MICRODOMAINS; MICROSCOPY, CONFOCAL; PROTO-ONCOGENE PROTEINS C-CBL; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; UBIQUITIN-CONJUGATING ENZYMES; VIRUS REPLICATION;

EID: 28844495621     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.immuni.2005.11.003     Document Type: Article

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