메뉴 건너뛰기




Volumn 36, Issue 10, 2011, Pages 927-938

Multidrug resistance-associated protein 1 (MRP1/ABCC1) polymorphism: From discovery to clinical application

Author keywords

ABCC1; Disease susceptibility; Drug resistance; Multidrug resistance associated protein 1; Prognosis; Single nucleotide polymorphism

Indexed keywords

ANTINEOPLASTIC AGENT; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1;

EID: 82555193825     PISSN: 16727347     EISSN: None     Source Type: Journal    
DOI: 10.3969/j.issn.1672-7347.2011.10.002     Document Type: Review
Times cited : (53)

References (73)
  • 1
    • 33745831231 scopus 로고    scopus 로고
    • Structure, function, expression, genomic organization, and single nucleotide polymorphisms of human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) efflux transporters
    • DOI 10.1080/10915810600746023, PII U1P538336R3G82J8
    • Choudhuri S, Klaassen C D. Structure, function, expression, genomic organization, and single nucleotide polymorphisms of human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) efflux transporters[J]. Int J Toxicol, 2006, 25(4) : 231-259. (Pubitemid 44034685)
    • (2006) International Journal of Toxicology , vol.25 , Issue.4 , pp. 231-259
    • Choudhuri, S.1    Klaassen, C.2
  • 2
    • 70249099233 scopus 로고    scopus 로고
    • Oligomerization of human ATP-binding cassette transporters and its potential significance in human disease [J]
    • Mo W, Zhang J T. Oligomerization of human ATP-binding cassette transporters and its potential significance in human disease [J]. Expert Opin Drug Metab Toxicol, 2009, 5(9): 1049-1063.
    • (2009) Expert Opin Drug Metab Toxicol , vol.5 , Issue.9 , pp. 1049-1063
    • Mo, W.1    Zhang, J.T.2
  • 4
    • 22944446748 scopus 로고    scopus 로고
    • Polymorphisms of MRP1 (ABCC1) and related ATP-dependent drug transporters
    • Conseil G, Deeley R G, Cole S P. Polymorphisms of MRP1 (ABCC1) and related ATP-dependent drug transporters [J]. Pharmacogenet Genomics, 2005, 15(8) :523-533. (Pubitemid 41044238)
    • (2005) Pharmacogenetics and Genomics , vol.15 , Issue.8 , pp. 523-533
    • Conseil, G.1    Deeley, R.G.2    Cole, S.P.C.3
  • 5
    • 0030726443 scopus 로고    scopus 로고
    • Analysis of the intronexon organization of the human multidrug-resistance protein gene (MRP) and alternative splicing of its mRNA [J]
    • Grant C E, Kurz E U, Cole S P, et al. Analysis of the intronexon organization of the human multidrug-resistance protein gene (MRP) and alternative splicing of its mRNA[J]. Genomics, 1997, 45(2) : 368-378.
    • (1997) Genomics , vol.45 , Issue.2 , pp. 368-378
    • Grant, C.E.1    Kurz, E.U.2    Cole, S.P.3
  • 6
    • 82555160698 scopus 로고    scopus 로고
    • Biochemistry and pharmacology of human ABCC1/MRP1 and its role in detoxification and in multidrug resistance of cancer chemotherapy in recent advances on cancer research and therapy [M]
    • Pestka S, Shi Y, Liu X Y. Elsevier, in press.
    • Mo W, Liu J Y, Zhang J T. Biochemistry and pharmacology of human ABCC1/MRP1 and its role in detoxification and in multidrug resistance of cancer chemotherapy in recent advances on cancer research and therapy[M]//Pestka S, Shi Y, Liu X Y. Recent advances on cancer research and therapy. Elsevier, 2011 (in press).
    • (2011) Recent Advances on Cancer Research and Therapy
    • Mo, W.1    Liu, J.Y.2    Zhang, J.T.3
  • 7
    • 0037113970 scopus 로고    scopus 로고
    • Structural and functional consequences of mutating cysteine residues in the amino terminus of human multidrug resistance-associated protein 1
    • DOI 10.1074/jbc.M207003200
    • Yang Y, Chen Q, Zhang J T. Structural and functional consequences of mutating cysteine residues in the amino terminus of human multidrug resistance-associated protein 1[J]. J Biol Chem, 2002, 277(46) : 44268-44277. (Pubitemid 36157860)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.46 , pp. 44268-44277
    • Yang, Y.1    Chen, Q.2    Zhang, J.-T.3
  • 8
    • 33750046916 scopus 로고    scopus 로고
    • The amino terminus of the human multidrug resistance transporter ABCC1 has a U-shaped folding with a gating function
    • DOI 10.1074/jbc.M603529200
    • Chen Q, Yang Y, Li L, et al. The amino terminus of the human multidrug resistance transporter ABCC1 has a U-shaped folding with a gating function[J]. J Biol Chem, 2006, 281 (41): 31152-31163. (Pubitemid 44582169)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.41 , pp. 31152-31163
    • Chen, Q.1    Yang, Y.2    Li, L.3    Zhang, J.-T.4
  • 9
    • 0037162429 scopus 로고    scopus 로고
    • Cytoplasmic retraction of the amino terminus of human multidrug resistance protein 1
    • DOI 10.1021/bi025634s
    • Chen Q, Yang Y, Liu Y, et al. Cytoplasmic retraction of the amino terminus of human multidrug resistance protein 1[J]. Biochemistry, 2002, 41(29) : 9052-9062. (Pubitemid 34787262)
    • (2002) Biochemistry , vol.41 , Issue.29 , pp. 9052-9062
    • Chen, Q.1    Yang, Y.2    Liu, Y.3    Han, B.4    Zhang, J.-T.5
  • 10
    • 0032744001 scopus 로고    scopus 로고
    • Structural, mechanistic and clinical aspects of MRPI [J]
    • [ Hipfner D R, Deeley R G, Cole S P, et al. Structural, mechanistic and clinical aspects of MRPI [J]. Biochim biophys Acta, 1999, 1461(2): 359-376.
    • (1999) Biochim Biophys Acta , vol.1461 , Issue.2 , pp. 359-376
    • Hipfner, D.R.1    Deeley, R.G.2    Cole, S.P.3
  • 11
    • 78650496066 scopus 로고    scopus 로고
    • Role of transmembrane segment 5 and extracellular loop 3 in the homodimerization of human ABCC1 [J]
    • Yang Y, Mo W, Zhang J T. Role of transmembrane segment 5 and extracellular loop 3 in the homodimerization of human ABCC1[J]. Biochemistry, 2010, 49(51): 10854-10861.
    • (2010) Biochemistry , vol.49 , Issue.51 , pp. 10854-10861
    • Yang, Y.1    Mo, W.2    Zhang, J.T.3
  • 12
    • 34247851070 scopus 로고    scopus 로고
    • Regulation of function by dimerization through the amino-terminal membrane-spanning domain of human ABCC1/MRP1
    • DOI 10.1074/jbc.M700152200
    • Yang Y, Liu Y, Dong Z, et al. Regulation of function by dimerization through the amino-terminal membrane-spanning domain of human ABCC1/MRP1 [J]. J Biol Chem, 2007, 282 (12): 8821-8830. (Pubitemid 47093510)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.12 , pp. 8821-8830
    • Yang, Y.1    Liu, Y.2    Dong, Z.3    Xu, J.4    Peng, H.5    Liu, Z.6    Zhang, J.-T.7
  • 13
    • 0001607723 scopus 로고
    • Distantly related sequences in the alpha-and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold [J]
    • [ Walker J E, Saraste M, Runswick M J, et al. Distantly related sequences in the alpha-and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold[J]. EMBO J, 1982, 1 (8) : 945-951.
    • (1982) EMBO J , vol.1 , Issue.8 , pp. 945-951
    • Walker, J.E.1    Saraste, M.2    Runswick, M.J.3
  • 14
    • 2442477649 scopus 로고    scopus 로고
    • Functional studies on the MRP1 multidrug transporter: Characterization of ABC-signature mutant variants
    • Szentpétery Z, Sarkadi B, Bakos E, et al. Functional studies on the MRP1 multidrug transporter :of ABC-signature mutant variants[ J]. Anticancer Res, 2004, 24(2A) : 449-455. (Pubitemid 38623119)
    • (2004) Anticancer Research , vol.24 , Issue.2 A , pp. 449-455
    • Szentpetery, Z.1    Sarkadi, B.2    Bakos, E.3    Varadi, A.4
  • 15
    • 4744347692 scopus 로고    scopus 로고
    • The role of the conserved glycines of ATP-binding cassette signature motifs of MRP1 in the communication between the substrate-binding site and the catalytic centers
    • DOI 10.1074/jbc.M406484200
    • Szentpétery Z, Kern A, Liliom K, et al. The role of the conserved glycines of ATP-binding cassette signature motifs of MRP1 in the communication between the substrate-binding site and the catalytic centers[J]. J Biol Chem, 2004, 279(40) : 41670-41678. (Pubitemid 39313612)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.40 , pp. 41670-41678
    • Szentpetery, Z.1    Kern, A.2    Liliom, K.3    Sarkadi, B.4    Varadi, A.5    Bakos, E.6
  • 18
    • 0033681486 scopus 로고    scopus 로고
    • Expression of members of the multidrug resistance protein family in human term placenta [J]
    • St-Pierre M V, Serrano M A, Macias RI, et al. Expression of members of the multidrug resistance protein family in human term placenta [J]. Am J Physiol Regul Integr Comp Physiol, 2000, 279(4) : R1495-R1503.
    • (2000) Am J Physiol Regul Integr Comp Physiol , vol.279 , Issue.4
    • St-Pierre, M.V.1    Serrano, M.A.2    Macias, R.I.3
  • 19
    • 33947397241 scopus 로고    scopus 로고
    • A molecular understanding of ATP-dependent solute transport by multidrug resistance-associated protein MRP1 [J]
    • Chang X B. A molecular understanding of ATP-dependent solute transport by multidrug resistance-associated protein MRP1 [J]. Cancer Metastasis Rev, 2007, 26(1): 15-37.
    • (2007) Cancer Metastasis Rev , vol.26 , Issue.1 , pp. 15-37
    • Chang, X.B.1
  • 21
    • 4344677966 scopus 로고    scopus 로고
    • Expression of P-glycoprotein (ABCB1) and Mrp1 (ABCC1) in adult rat brain: Focus on astrocytes
    • DOI 10.1016/j.brainres.2004.06.034, PII S0006899304009448
    • Mercier C, Masseguin C, Roux F, et al. Expression of P-glycoprotein (ABCB1) and Mrpl (ABCC1) in adult rat brain:focus on astrocytes[J]. Brain Res, 2004, 1021(1) :32-40. (Pubitemid 39158654)
    • (2004) Brain Research , vol.1021 , Issue.1 , pp. 32-40
    • Mercier, C.1    Masseguin, C.2    Roux, F.3    Gabrion, J.4    Scherrmann, J.-M.5
  • 22
    • 0029995238 scopus 로고    scopus 로고
    • Basolateral locali-zation and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells [J]
    • Evers R, Zaman G J, van Deemter L, et al. Basolateral locali-zation and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells[J]. J Clin Invest, 1996, 97(5): 1211-1218.
    • (1996) J Clin Invest , vol.97 , Issue.5 , pp. 1211-1218
    • Evers, R.1    Zaman, G.J.2    Van Deemter, L.3
  • 23
    • 0031058993 scopus 로고    scopus 로고
    • Increased levels of the multidrug resistance protein in lateral membranes of proliferating hepatocyte-derived cells
    • DOI 10.1053/gast.1997.v112.pm9024305
    • Roelofsen H, Vos T A, Schippers IJ, et al. Increased levels of the multidrug resistance protein in lateral membranes of proliferating hepatocyte-derived cells [ J ]. Gastroenterology, 1997, 112(2): 511-521. (Pubitemid 27078838)
    • (1997) Gastroenterology , vol.112 , Issue.2 , pp. 511-521
    • Roelofsen, H.1    Vos, T.A.2    Schippers, I.J.3    Kuipers, F.4    Koning, H.5    Moshage, H.6    Jansen, P.L.M.7    Muller, M.8
  • 24
    • 62349110987 scopus 로고    scopus 로고
    • Characterization and analyses of multidrug resistance-associated protein 1 (MRP1/ ABCC1) polymorphisms in Chinese population [J]
    • Yin J Y, Huang Q, Yang Y, et al. Characterization and analyses of multidrug resistance-associated protein 1 (MRP1/ ABCC1) polymorphisms in Chinese population [ J ]. Pharmacogenet Genomics, 2009, 19(3) : 206-216.
    • (2009) Pharmacogenet Genomics , vol.19 , Issue.3 , pp. 206-216
    • Yin, J.Y.1    Huang, Q.2    Yang, Y.3
  • 25
    • 0035813012 scopus 로고    scopus 로고
    • Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters
    • DOI 10.1016/S0300-483X(01)00454-1, PII S0300483X01004541
    • Leslie E M, Deeley R G, Cole C P. Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters[J]. Toxicology, 2001, 167(1); 3-23. (Pubitemid 32830943)
    • (2001) Toxicology , vol.167 , Issue.1 , pp. 3-23
    • Leslie, E.M.1    Deeley, R.G.2    Cole, S.P.C.3
  • 26
    • 0032434272 scopus 로고    scopus 로고
    • Excretion of GSSG and glutathione conjugates mediated by MRP1 and cMOAT/MRP2
    • Suzuki H, Sugiyama Y. Excretion of GSSG and glutathione conjugates mediated by MRP1 and cmoat/MRP2 [J]. Semin Liver Dis, 1998, 18(4) : 359-376. (Pubitemid 29011040)
    • (1998) Seminars in Liver Disease , vol.18 , Issue.4 , pp. 359-376
    • Suzuki, H.1    Sugiyama, Y.2
  • 29
    • 62349095936 scopus 로고    scopus 로고
    • 5-lipoxygenase pharmacogenetics in asthma; overlap with cys-leukotriene receptor antagonist loci [J]
    • Tantisira K G, Lima J, Sylvia J, et al. 5-lipoxygenase pharmacogenetics in asthma; overlap with cys-leukotriene receptor antagonist loci [J]. Pharmacogenet Genomics, 2009, 19(3): 244-247.
    • (2009) Pharmacogenet Genomics , vol.19 , Issue.3 , pp. 244-247
    • Tantisira, K.G.1    Lima, J.2    Sylvia, J.3
  • 32
    • 0041410061 scopus 로고    scopus 로고
    • Frequency of MRP1 genetic polymorphisms and their functional significance in caucasians: Detection of a novel mutation G816A in the human MRP1 gene
    • DOI 10.1007/s00228-003-0625-z
    • Oselin K, Mrozikiewicz P M, Gaikovitch E, et al. Frequency of MRP1 genetic polymorphisms and their functional significance in Caucasians : detection of a novel mutation G816a in the human MRP1 gene[J]. Eur J Clin Pharmacol, 2003, 59(4) : 347-350. (Pubitemid 37100355)
    • (2003) European Journal of Clinical Pharmacology , vol.59 , Issue.4 , pp. 347-350
    • Oselin, K.1    Mrozikiewicz, P.M.2    Gaikovitch, E.3    Pahkla, R.4    Roots, I.5
  • 33
    • 34047276125 scopus 로고    scopus 로고
    • Genetic variations and haplotype structures of the ABC transporter gene ABCC1 in a japanese population [J]
    • Fukushima-Uesaka H, Saito Y, Tohkin M, et al. Genetic variations and haplotype structures of the ABC transporter gene ABCC1 in a japanese population[ J]. Drug Metab Pharmacokinet, 2007, 22(1): 48-60.
    • (2007) Drug Metab Pharmacokinet , vol.22 , Issue.1 , pp. 48-60
    • Fukushima-Uesaka, H.1    Saito, Y.2    Tohkin, M.3
  • 34
    • 0035212059 scopus 로고    scopus 로고
    • Identification of human multidrug resistance protein 1 (MRP1) mutations and characterization of a G671V substitution
    • DOI 10.1007/s100380170017
    • Conrad S, Kauffmann H M, Ito K, et al. Identification of human multidrug resistance protein 1(MRP1) mutations and characterization of a G671V substitution[J]. J Hum Genet, 2001, 46(11): 656-663. (Pubitemid 33134743)
    • (2001) Journal of Human Genetics , vol.46 , Issue.11 , pp. 656-663
    • Conrad, S.1    Kauffmann, H.-M.2    Ito, K.3    Deeley, R.G.4    Cole, S.P.C.5    Schrenk, D.6
  • 35
    • 0035219750 scopus 로고    scopus 로고
    • Identification of novel polymorphisms in the pM5 and MRP1 (ABCC1) genes at locus 16p13. 1 and exclusion of both genes as responsible for pseudoxanthoma elasticum [J]
    • Perdu J, Germain D P. Identification of novel polymorphisms in the pM5 and MRP1 (ABCC1) genes at locus 16p13. 1 and exclusion of both genes as responsible for pseudoxanthoma elasticum [J]. Hum Mutat, 2001, 17(1): 74-75.
    • (2001) Hum Mutat , vol.17 , Issue.1 , pp. 74-75
    • Perdu, J.1    Germain, D.P.2
  • 36
    • 11144329541 scopus 로고    scopus 로고
    • Linkage disequilibrium and haplotype architecture for two ABC transporter genes (ABCC1 and ABCG2) in Chinese population: Implications for pharmacogenomic association studies
    • DOI 10.1046/j.1529-8817.2003.00124.x
    • Wang H, Hao B, Zhou K, et al. Linkage disequilibrium and haplotype architecture for two ABC transporter genes (ABCC1 and ABCG2) in Chinese population : implications for pharmacogenomic association studies[J]. Ann Hum Genet, 2004, 68 (Pt 6): 563-573. (Pubitemid 40028442)
    • (2004) Annals of Human Genetics , vol.68 , Issue.6 , pp. 563-573
    • Wang, H.1    Hao, B.2    Zhou, K.3    Chen, X.4    Wu, S.5    Zhou, G.6    Zhu, Y.7    He, F.8
  • 37
    • 0035103009 scopus 로고    scopus 로고
    • Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects
    • DOI 10.1097/00008571-200103000-00008
    • Ito S, Ieiri I, Tanabe M, et al. Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cmoat, in healthy japanese subjects[ J]. Pharmacogenetics, 2001, 11(2); 175-184. (Pubitemid 32216128)
    • (2001) Pharmacogenetics , vol.11 , Issue.2 , pp. 175-184
    • Ito, S.1    Ieiri, I.2    Tanabe, M.3    Suzuki, A.4    Higuchi, S.5    Otsubo, K.6
  • 38
    • 33745769743 scopus 로고    scopus 로고
    • Nucleotide sequence analyses of the MRP1 gene in four populations suggest negative selection on its coding region [J]
    • Wang Z, Sew P H, Ambrose H, et al. Nucleotide sequence analyses of the MRP1 gene in four populations suggest negative selection on its coding region[J]. BMC Genomics, 2006, 7: 111.
    • (2006) BMC Genomics , vol.7 , pp. 111
    • Wang, Z.1    Sew, P.H.2    Ambrose, H.3
  • 39
    • 23444447815 scopus 로고    scopus 로고
    • Functional characterization of non-synonymous single nucleotide polymorphisms in the gene encoding human multidrug resistance protein 1 (MRP1/ABCC1)
    • Létourneau I J, Deeley R G, Cole S P. Functional characterization of non-synonymous single nucleotide polymorphisms in the gene encoding human multidrug resistance protein 1 (MRP1/ABCC1) [J]. Pharmacogenet Genomics, 2005, 15 (9) : 647-657. (Pubitemid 41113337)
    • (2005) Pharmacogenetics and Genomics , vol.15 , Issue.9 , pp. 647-657
    • Letourneau, I.J.1    Deeley, R.G.2    Cole, S.P.C.3
  • 41
    • 26444438734 scopus 로고    scopus 로고
    • A functional polymorphism within the MRP1 gene locus identified through its genomic signature of positive selection
    • DOI 10.1093/hmg/ddi212
    • Wang Z, Wang B, Tang K, et al. A functional polymorphism within the MRP1 gene locus identified through its genomic signature of positive selection [ J ]. Hum Mol Genet, 2005, 14 (14): 2075-2087. (Pubitemid 41418043)
    • (2005) Human Molecular Genetics , vol.14 , Issue.14 , pp. 2075-2087
    • Wang, Z.1    Wang, B.2    Tang, K.3    Lee, E.J.D.4    Chong, S.S.5    Lee, C.G.L.6
  • 42
    • 56649105136 scopus 로고    scopus 로고
    • ABCB1 and ABCC1 expression in peripheral mononuclear cells is influenced by gene polymorphisms and atorvastatin treatment [J]
    • Moretti I R, Cristina A R, Sorkin S A, et al. ABCB1 and ABCC1 expression in peripheral mononuclear cells is influenced by gene polymorphisms and atorvastatin treatment [J]. Biochem Pharmacol, 2009, 77 (1) : 66-75.
    • (2009) Biochem Pharmacol , vol.77 , Issue.1 , pp. 66-75
    • Moretti, I.R.1    Cristina, A.R.2    Sorkin, S.A.3
  • 43
    • 59449089550 scopus 로고    scopus 로고
    • MRP1 polymorphisms(T2684C, C2007T, C2012T, and C2665T) are not associated with multidrug resistance in leukemic patients [J]
    • Mahjoubi F, Akbari S, Montazeri M, et al. MRP1 polymorphisms(T2684C, C2007T, C2012T, and C2665T) are not associated with multidrug resistance in leukemic patients[J]. Genet Mol Res, 2008, 7(4) : 1369-1374.
    • (2008) Genet Mol Res , vol.7 , Issue.4 , pp. 1369-1374
    • Mahjoubi, F.1    Akbari, S.2    Montazeri, M.3
  • 44
    • 79151468933 scopus 로고    scopus 로고
    • Pharmacogenetics of telatinib, a VEGFR-2 and VEGFR-3 tyrosine kinase inhibitor, used in patients with solid tumors [J]
    • Steeghs N, Gelderblom H, Wessels J, et al. Pharmacogenetics of telatinib, a VEGFR-2 and VEGFR-3 tyrosine kinase inhibitor, used in patients with solid tumors[J]. Invest New Drugs, 2011, 29(1); 137-143.
    • (2011) Invest New Drugs , vol.29 , Issue.1 , pp. 137-143
    • Steeghs, N.1    Gelderblom, H.2    Wessels, J.3
  • 45
    • 79551690986 scopus 로고    scopus 로고
    • Association of multidrug resistance gene polymorphisms with pancreatic cancer outcome [J]
    • Tanaka M, Okazaki T, Suzuki H, et al. Association of multidrug resistance gene polymorphisms with pancreatic cancer outcome[J]. Cancer, 2011, 117(4): 744-751.
    • (2011) Cancer , vol.117 , Issue.4 , pp. 744-751
    • Tanaka, M.1    Okazaki, T.2    Suzuki, H.3
  • 47
    • 35648997048 scopus 로고    scopus 로고
    • Pharmacogenetic assessment of toxicity and outcome after platinum plus taxane chemotherapy in ovarian cancer: The scottish randomised trial in ovarian cancer
    • DOI 10.1200/JCO.2006.10.4752
    • Marsh S, Paul J, King C R, et al. Pharmacogenetic assessment of toxicity and outcome after platinum plus taxane chemotherapy in ovarian cancer :the scottish randomised trial in ovarian cancer [J]. J Clin Oncol, 2007, 25(29) : 4528-4535. (Pubitemid 350035308)
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.29 , pp. 4528-4535
    • Marsh, S.1    Paul, J.2    King, C.R.3    Gifford, G.4    McLeod, H.L.5    Brown, R.6
  • 48
    • 77952162644 scopus 로고    scopus 로고
    • MRP1 polymorphisms associated with citalopram response in patients with major depression [J]
    • Lee S H, Lee M S, Lee J H, et al. MRP1 polymorphisms associated with citalopram response in patients with major depression[J]. J Clin Psychopharmacol, 2010, 30(2) : 116-125.
    • (2010) J Clin Psychopharmacol , vol.30 , Issue.2 , pp. 116-125
    • Lee, S.H.1    Lee, M.S.2    Lee, J.H.3
  • 49
    • 47349093732 scopus 로고    scopus 로고
    • Genetic variation in efflux transporters influences outcome to methotrexate therapy in patients with psoriasis [J]
    • Warren R B, Smith R L, Campalani E, et al. Genetic variation in efflux transporters influences outcome to methotrexate therapy in patients with psoriasis[ J]. J Invest Dermatol, 2008, 128 (8): 1925-1929.
    • (2008) J Invest Dermatol , vol.128 , Issue.8 , pp. 1925-1929
    • Warren, R.B.1    Smith, R.L.2    Campalani, E.3
  • 50
    • 33745535229 scopus 로고    scopus 로고
    • Association between single nucleotide polymorphisms of drug resistance-associated genes and response to chemotherapy in advanced ovarian cancer
    • Obata H, Yahata T, Quan J, et al. Association between single nucleotide polymorphisms of drug resistance-associated genes and response to chemotherapy in advanced ovarian cancer[ J ]. Anticancer Res, 2006, 26(3B) : 2227-2232. (Pubitemid 43980177)
    • (2006) Anticancer Research , vol.26 , Issue.3 B , pp. 2227-2232
    • Obata, H.1    Yahata, T.2    Quan, J.3    Sekine, M.4    Tanaka, K.5
  • 51
    • 70249108809 scopus 로고    scopus 로고
    • ABCC1 polymorphisms contribute to level and decline of lung function in two population-based cohorts [J]
    • Siedlinski M, Boezen H M, Boer J M, et al. ABCC1 polymorphisms contribute to level and decline of lung function in two population-based cohorts [J]. Pharmacogenet Genomics, 2009, 19(9): 675-684.
    • (2009) Pharmacogenet Genomics , vol.19 , Issue.9 , pp. 675-684
    • Siedlinski, M.1    Boezen, H.M.2    Boer, J.M.3
  • 52
    • 79955483887 scopus 로고    scopus 로고
    • ABCC1 G2012T single nucleotide polymorphism is associated with patient outcome in primary neuroblastoma and altered stability of the ABCC1 gene transcript [J]
    • Pajic M, Murray J, Marshall G M, et al. ABCC1 G2012T single nucleotide polymorphism is associated with patient outcome in primary neuroblastoma and altered stability of the ABCC1 gene transcript[ J]. Pharmacogenet Genomics, 2011, 21 (5) : 270-279.
    • (2011) Pharmacogenet Genomics , vol.21 , Issue.5 , pp. 270-279
    • Pajic, M.1    Murray, J.2    Marshall, G.M.3
  • 53
    • 78650793130 scopus 로고    scopus 로고
    • Promoter polymorphism of MRPl associated with reduced survival in hepatocellular carcinoma [J]
    • Zhao J, Yu B Y, Wang D Y, et al. Promoter polymorphism of MRPl associated with reduced survival in hepatocellular carcinoma[J]. World J Gastroenterol, 2010, 16(48); 6104-6110.
    • (2010) World J Gastroenterol , vol.16 , Issue.48 , pp. 6104-6110
    • Zhao, J.1    Yu, B.Y.2    Wang, D.Y.3
  • 54
    • 66849111193 scopus 로고    scopus 로고
    • Comprehensive pharmacogenetic analysis of irinotecan neutropenia and pharmacokinetics [J]
    • Innocenti F, Kroetz D L, Schuetz E, et al. Comprehensive pharmacogenetic analysis of irinotecan neutropenia and pharmacokinetics[J]. J Clin Oncol, 2009, 27(16); 2604-2614.
    • (2009) J Clin Oncol , vol.27 , Issue.16 , pp. 2604-2614
    • Innocenti, F.1    Kroetz, D.L.2    Schuetz, E.3
  • 55
    • 78049528598 scopus 로고    scopus 로고
    • Mechanisms of peripheral neuropathy associated with bortezomib and vincristine in patients with newly diagnosed multiple myeloma: A prospective analysis of data from the hovon-65/GMMG-HD4 trial [J]
    • Annemiek B, Corthals S L, Jongen L J, et al. Mechanisms of peripheral neuropathy associated with bortezomib and vincristine in patients with newly diagnosed multiple myeloma : a prospective analysis of data from the hovon-65/GMMG-HD4 trial [J]. Lancet Oncol, 2010, 11(11): 1057-1065.
    • (2010) Lancet Oncol , vol.11 , Issue.11 , pp. 1057-1065
    • Annemiek, B.1    Corthals, S.L.2    Jongen, L.J.3
  • 57
    • 0041968944 scopus 로고    scopus 로고
    • Subcellular localization and activity of multidrug resistance proteins
    • DOI 10.1091/mbc.E02-11-0704
    • Rajagopal A, Simon S M. Subcellular localization and activity of multidrug resistance proteins[J]. Mol Biol Cell, 2003, 14 (8): 3389-3399. (Pubitemid 37013135)
    • (2003) Molecular Biology of the Cell , vol.14 , Issue.8 , pp. 3389-3399
    • Rajagopal, A.1    Simon, S.M.2
  • 58
    • 60049083014 scopus 로고    scopus 로고
    • Genetic susceptibility of lung cancer associated with common variants in the 3 untranslated regions of the adenosine triphosphate-binding cassette B1 (ABCB1)and ABCC1 candidate transporter genes for carcinogen export [J]
    • Wang H, Jin G, Wang H, et al. Genetic susceptibility of lung cancer associated with common variants in the 3 untranslated regions of the adenosine triphosphate-binding cassette B1 (ABCB1)and ABCC1 candidate transporter genes for carcinogen export[J]. Cancer, 2009, 115(3); 595-607.
    • (2009) Cancer , vol.115 , Issue.3 , pp. 595-607
    • Wang, H.1    Jin, G.2    Wang, H.3
  • 59
    • 80052078323 scopus 로고    scopus 로고
    • ABCC1 polymorphism Arg723Gln (2168G > A) is associated with lung cancer susceptibility in a Chinese population [J]
    • Yin J Y, Han L F, Huang Q, et al. ABCC1 polymorphism Arg723Gln (2168G > A) is associated with lung cancer susceptibility in a Chinese population [J]. Clin Exp Pharmacol Physiol, 2011, 38(9) :632-637.
    • (2011) Clin Exp Pharmacol Physiol , vol.38 , Issue.9 , pp. 632-637
    • Yin, J.Y.1    Han, L.F.2    Huang, Q.3
  • 60
    • 79958274672 scopus 로고    scopus 로고
    • Impact of polymorphism of multidrug resistance-associated protein 1 ABCC1 gene on the severity of cystic fibrosis [J]
    • Mafficini A, Ortombina M, Sermet-Gaudelius I, et al. Impact of polymorphism of multidrug resistance-associated protein 1 ABCC1 gene on the severity of cystic fibrosis[J]. J Cyst Fibros, 2011, 10(4) :228-233.
    • (2011) J Cyst Fibros , vol.10 , Issue.4 , pp. 228-233
    • Mafficini, A.1    Ortombina, M.2    Sermet-Gaudelius, I.3
  • 61
    • 77956736290 scopus 로고    scopus 로고
    • Multidrug resistance-associated protein-1 (MR1Pl) genetic variants, MRP1 protein levels and severity of COPD [J]
    • Budulac S E, Postma D S, Hiemstra P S, et al. Multidrug resistance-associated protein-1 (MR1Pl) genetic variants, MRP1 protein levels and severity of COPD [ J ]. Respir Res, 2010, 11 : 60.
    • (2010) Respir Res , vol.11 , pp. 60
    • Budulac, S.E.1    Postma, D.S.2    Hiemstra, P.S.3
  • 62
    • 79959503826 scopus 로고    scopus 로고
    • The international hapmap project [J]
    • International HapMap Consortium.
    • International HapMap Consortium. The international hapmap project[J]. Nature, 2003, 426(6968) :789-796.
    • (2003) Nature , vol.426 , Issue.6968 , pp. 789-796
  • 63
    • 78049359286 scopus 로고    scopus 로고
    • Genomics. 1000 genomes project gives new map of genetic diversity [J]
    • Pennisi E. Genomics. 1000 genomes project gives new map of genetic diversity[J]. Science, 2010, 330(6004) :574-575.
    • (2010) Science , vol.330 , Issue.6004 , pp. 574-575
    • Pennisi, E.1
  • 65
    • 0035026704 scopus 로고    scopus 로고
    • Predicting deleterious amino acid substitutions
    • DOI 10.1101/gr.176601
    • Ng P C, Henikoff S. Predicting deleterious amino acid substitutions[J]. Genome Res, 2001, 11(5) :863-874. (Pubitemid 32447869)
    • (2001) Genome Research , vol.11 , Issue.5 , pp. 863-874
    • Ng, P.C.1    Henikoff, S.2
  • 66
    • 66949150575 scopus 로고    scopus 로고
    • Predicting potentially functional SNPs in drug-response genes [J]
    • Pang G S, Wang J, Wang Z, et al. Predicting potentially functional SNPs in drug-response genes [J]. Pharmacogenomics, 2009, 10(4): 639-653.
    • (2009) Pharmacogenomics , vol.10 , Issue.4 , pp. 639-653
    • Pang, G.S.1    Wang, J.2    Wang, Z.3
  • 68
    • 0037307413 scopus 로고    scopus 로고
    • Signatures of natural selection in the human genome
    • DOI 10.1038/nrg999
    • Bamshad M, Wooding S P. Signatures of natural selection in the human genome[J]. Nat Rev Genet, 2003, 4(2); 99-111. (Pubitemid 36150682)
    • (2003) Nature Reviews Genetics , vol.4 , Issue.2 , pp. 99-111
    • Bamshad, M.1    Wooding, S.P.2
  • 71
    • 40949121607 scopus 로고    scopus 로고
    • ABC multidrug transporters: Structure, function and role in chemoresistance
    • DOI 10.2217/14622416.9.1.105
    • Sharom F J. ABC multidrug transporters; structure, function and role in chemoresistance[ J]. Pharmacogenomics, 2008, 9(1); 105-127. (Pubitemid 351560534)
    • (2008) Pharmacogenomics , vol.9 , Issue.1 , pp. 105-127
    • Sharom, F.J.1
  • 72
    • 32944480006 scopus 로고    scopus 로고
    • The GCC repeat length in the 5'UTR of MRP1 gene is polymorphic; a functional characterization of its relevance for cystic fibrosis [J]
    • Nicolis E, Pasetto M, Cigana C, et al. The GCC repeat length in the 5'UTR of MRP1 gene is polymorphic; a functional characterization of its relevance for cystic fibrosis [J]. BMC Med Genet, 2006, 7-7.
    • (2006) BMC Med Genet , pp. 7-7
    • Nicolis, E.1    Pasetto, M.2    Cigana, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.