Betel nut extract and arecoline block insulin signaling and lipid storage in 3T3-L1 adipocytes

Cell Biology and Toxicology

Volumn 27, Issue 6, 2011, Pages 397-411

  Hsieh, Tusty Jiuan ^a   Hsieh, Pei Chen ^b   Wu, Ming Tsang ^b,c,d   Chang, Wei Chiao ^a   Hsiao, Pi Jung ^c   Lin, Kun Der ^c   Chou, Pong Chun ^c   Shin, Shyi Jang ^a,c  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d KAOHSIUNG MUNICIPAL HSIAO KANG HOSPITAL   (Taiwan)

Author keywords

Betel nut; Diabetes; Insulin resistance; IRS 1; Perilipin

Indexed keywords

ADIPOPHILIN; ARECOLINE; CCAAT ENHANCER BINDING PROTEIN BETA; FAT DROPLET; FATTY ACID SYNTHASE; GLUCOSE TRANSPORTER 4; HERBACEOUS AGENT; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; PERILIPIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SERINE; TYROSINE;

ARTICLE; BETEL NUT; CELL DIFFERENTIATION; CELL STIMULATION; CELL STRAIN 3T3; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIABETOGENESIS; DRUG MECHANISM; INSULIN RESISTANCE; INSULIN RESPONSE; INSULIN SIGNALING; LIPID STORAGE; METABOLIC INHIBITION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION; REAL TIME POLYMERASE CHAIN REACTION;

3T3-L1 CELLS; ADIPOCYTES; ANIMALS; ARECA; ARECOLINE; CARRIER PROTEINS; DIABETES MELLITUS, TYPE 2; FATTY ACID SYNTHETASE COMPLEX; GENE EXPRESSION; GLUCOSE; GLUCOSE TRANSPORTER TYPE 4; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; LIPID METABOLISM; MEMBRANE PROTEINS; MICE; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHOPROTEINS; PHOSPHORYLATION; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

PIPER BETEL;

EID: 82455199301     PISSN: 07422091     EISSN: 15736822     Source Type: Journal    
DOI: 10.1007/s10565-011-9195-5     Document Type: Article

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