The medicinal Agaricus mushroom cultivated in Brazil: Biology, cultivation and non-medicinal valorisation

Applied Microbiology and Biotechnology

Volumn 92, Issue 5, 2011, Pages 897-907

  Largeteau, Michèle L ^a   Llarena Hernández, Régulo Carlos ^a   Regnault Roger, Catherine ^b   Savoie, Jean Michel ^a  

^a CEMAGREF   (France)

^b UNIVERSITÉ DE PAU ET DES PAYS DE L'ADOUR   (France)

Author keywords

Agaricus blazei; Agaricus brasiliensis; Agaricus subrufescens; Biology; Cultivation; Genetic variability; Marketing; Non medicinal use; Pathology; Production areas

Indexed keywords

AGARICUS BLAZEI; AGARICUS BRASILIENSIS; AGARICUS SUBRUFESCENS; GENETIC VARIABILITY; NON-MEDICINAL USE; PRODUCTION AREAS;

BIOLOGY; FUNGI; MARKETING; MOLECULAR BIOLOGY; PATHOLOGY;

CULTIVATION;

FOOD ADDITIVE; FRAGRANCE; LIGNOCELLULOSE;

AGRONOMY; CROP PRODUCTION; CULTIVATION; ENZYME ACTIVITY; FUNGUS; GENETIC VARIATION; LABORATORY METHOD; MEDICINAL PLANT; MUSHROOM; PATHOLOGY;

AGARICUS; AGARICUS BISPORUS; BIOLOGY; BRAZIL; CULTIVAR; ENZYME RELEASE; FRUITING; FUNGAL STRAIN; FUNGUS CULTURE; GENETIC POLYMORPHISM; GENETIC VARIABILITY; IN VITRO STUDY; LABORATORY; MARKETING; MUSHROOM; MYCELIUM; NONHUMAN; NUTRITIONAL VALUE; PLANT DISEASE; REVIEW; SPAWNING; SPECIES CULTIVATION; TASTE;

AGARICUS; BRAZIL; CULTURE TECHNIQUES; FUNCTIONAL FOOD; FUNGAL PROTEINS; NUTRITIVE VALUE; PLANT DISEASES;

BRAZIL;

AGARICUS; AGARICUS BISPORUS; AGARICUS BLAZEI; AGARICUS BRASILIENSIS; AGARICUS SUBRUFESCENS; BASIDIOMYCOTA; FUNGI;

EID: 82355181033     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-011-3630-7     Document Type: Review

References (83)

1. MCN Andrade DC Zied MTA Minhoni J Kopytowski Filho 2008 Yield of four A. bisporus strains in three compost formulations and chemical composition analyses of the mushrooms Braz J Microbiol 39 593 598 10.1590/S1517-83822008000300034
2. MCN Andrade J Kopytowski Filho MTA Minhoni LN Coutinho MB Figueiredo 2007 Productivity, biological efficiency, and number of Agaricus blazei mushrooms grown in compost in the presence of Trichoderma sp. and Chaetomium olivaceum contaminants Braz J Microbiol 38 243 247 10.1590/S1517-83822007000200010 (Pubitemid 47037411)
3. GC Braga AF Eira 1999 Productivity of Agaricus blazei Murril in relation to the cultivation environment, the substrate mass, and the casing layer Energia na Agricultura 14 39 51
4. GC Braga RMC Montini AB Salibe 2006 Parâmetros da produção de Agaricus blazei sob diferentes condições ambientais de cultivo Scientia Agraria Paranaensis 5 47 56
5. CM Camelini M Maraschin M Matos de Mendonça C Zucco AG Ferreira LA Tavares 2005 Structural characterization of β-glucans of Agaricus brasiliensis in different stages of fruiting body maturity and their use in nutraceutical products Biotechnol Lett 27 1295 1299 1:CAS:528:DC%2BD2MXhtVyltbbI 10.1007/s10529-005-0222-6 (Pubitemid 41428179)
6. JLR Cavalcante VFF Gomes 2005 Cultivo do Agaricus blazei (Murrill) no Estrado do Ceará Rev Ciênc Agron 36 255 261
7. JLR Cavalcante VFF Gomes J Kopytowski Filho MTA Minhoni MCN Andrade 2008 Cultivation of Agaricus blazei in the environmental protection area of the Barturité region under three types of casing soils Acta Sci Agron 30 513 517
8. HL Chang GR Chao CC Chen JL Mau 2001 Non-volatile taste components of Agaricus blazei, Antrodia camphorata and Cordyceps militaris mycelia Food Chem 74 203 207 1:CAS:528:DC%2BD3MXkvFyis7c%3D 10.1016/S0308-8146(01)00127-3 (Pubitemid 32655467)
9. NB Colauto AR Silveira AF Eira GA Linde 2010 Alternative to peat for Agaricus brasiliensis yield Bioresour Technol 101 712 716 1:CAS:528: DC%2BD1MXht1amu7rO 10.1016/j.biortech.2009.08.052
10. NB Colauto ES Dias MA Gimenes AF Eira 2002 Genetic characterization of isolates of the basidiomycete Agaricus blazei by RAPD Braz J Microbiol 33 131 133 1:CAS:528:DC%2BD3sXmtFSqtLs%3D 10.1590/S1517-83822002000200006 (Pubitemid 40747584)
11. NB Colauto PM Aizono LRM Carvalho LD Paccola-Meirelles GA Linde 2008 Temperature and pH conditions for mycelial growth of Agaricus brasiliensis on axenic cultivation Cienc Agrár 29 307 312
12. AC Da Silva MD Oliveira PV Del Ré N Jorge 2009 Utilização de extrato de cogumelo como antioxidante natural em óleo vegetal Ciênc Agrotec 33 1103 1108
13. ES Dias 2010 Mushroom cultivation in Brazil: challenges and potential for growth Ciênc Agrotec 34 795 803 10.1590/S1413-70542010000400001
14. ES Dias C Abe RF Schwan 2004 Truths and myths about the mushroom Agaricus blazei Sci Agric 61 545 549 10.1590/S0103-90162004000500014 (Pubitemid 39660012)
15. ES Dias SE Guimarães FG Siqueira R Silva LR Batista 2009 Fungos alergênicos e toxigênicos in the compost de cultivo de Agaricus brasiliensis Sci Agrár 10 507 511
16. RM Di Piero QS Novaes SF Pascholati 2010 Effect of Agaricus brasiliensis and Lentinula edodes mushrooms on the infection of passionflower with Cowpea aphid-borne mosaic virus Braz Arch Biol Technol 53 269 278 10.1590/S1516- 89132010000200004
17. Eira AF (2003) Cultivo do cogumelo medicinal Agaricus blazei (Murril) ss. Heinemann. Viçosa, BR, Aprenda Fácil (ed)
18. L Fan T Soccol A Pandey CR Soccol 2007 Effect of nutritional and environmental conditions on the production of exo-polysaccharide of Agaricus brasiliensis by submerged fermentation and its antitumor activity LWT-Food Sci Technol 40 30 35 1:CAS:528:DC%2BD28Xns1Kiu7w%3D 10.1016/j.lwt.2005.09.006 (Pubitemid 44150588)
19. ACG Fiori-Tutida KRF Schwan-Estrada JR Stangarlin SF Pascholati 2007 Extratos de Lentinula edodes e Agaricus blazei sobre Bipolaris sorokinioana and Puccinia recondita f. sp. tritici, in vitro Summa Phytopathol 33 113 118 10.1590/S0100-54052007000300013
20. F Firenzuoli L Gori G Lombardo 2008 The Medicinal mushroom Agaricus blazei Murill Review of literature and pharmaco-toxicological problems eCAM 5 3 15 1:STN:280:DC%2BD1c7lvVKiuw%3D%3D (Pubitemid 351301956)
21. Fletcher JT, White PF, Gaze RH (1989) Mushrooms: pest and Disease Control. 2nd edn. Newcastle upon Tyne, GB, Intercept Limited (ed)
22. M Foulongne-Oriol C Spataro J-M Savoie 2009 Novel microsatellite markers suitable for genetic studies in the white button mushroom Agaricus bisporus Appl Microbiol Biotechnol 84 1125 1135 1:CAS:528:DC%2BD1MXht1Sqs7jE 10.1007/s00253-009-2030-8
23. M Fukuda S Ohno M Kato 2003 Genetic variation in cultivated strains of Agaricus blazei Mycoscience 44 431 436 1:CAS:528:DC%2BD2cXitFWhtbo%3D 10.1007/s10267-003-0136-x (Pubitemid 38258743)
24. H Gao W-Y Gu 2007 Optimization of polysaccharide and ergosterol production from A. brasiliensis by fermentation process Biochem Eng J 33 202 210 1:CAS:528:DC%2BD2sXhvVyrsL8%3D 10.1016/j.bej.2006.10.022 (Pubitemid 46241011)
25. FJ Gea A Pardo-Giménez A MartÍnez-Carrasco MJ Navarro DC Zied 2010 Daños ocasionados por falsa trufa (Diehliomyces microsporus) en Agaricus blazei en España Bol. San. Veg. Plagas 36 233 238
26. Gene B (2009) Medicinal mushrooms. Smart supplementation™. www.hchs.edu/freeliterature.htm
27. A Gregori B Pahor R Glaser F Pohleven 2008 Influence of carbon dioxide, inoculum rate, amount and mixing of casing soil on Agaricus blazei fruiting bodies yield Acta agriculturae Slovenica 91 371 378 10.2478/v10014-008-0017-2
28. X-J Guan L Xu Y-C Shao Z-R Wang F-S Chen X-C Luo 2008 Differentiation of commercial strains of Agaricus species in China with inter-simple sequence repeat marker World J Microbiol Biotechnol 24 1617 1622 1:CAS:528: DC%2BD1cXnsVCqtr4%3D 10.1007/s11274-007-9647-5
29. V Horm S Ohga 2008 Potential of compost with some added supplementary materials on the development of Agaricus blazei Murill J Fac Agr Kyushu Univ 53 417 422 1:CAS:528:DC%2BD1MXisFCjtLc%3D
30. H Kawagishi RI Ryuichi T Kanao TM Keishiro S Hitoshi IT Hagiwara T Nakamura 1989 Fractionation and antitumor activity of the water-insoluble residue of Agaricus blazei fruiting body Carbohyd Res 186 267 273 1:CAS:528:DyaL1MXhslShuro%3D 10.1016/0008-6215(89)84040-6
31. RW Kerrigan 2005 Agaricus subrufescens, a cultivated edible and medicinal mushroom, and its synonyms Mycologia 97 12 24 10.3852/mycologia.97.1.12 (Pubitemid 40722059)
32. RW Kerrigan 2007 Inclusive and exclusive concepts of Agaricus subrufescens peck: a reply to Wasser et al Int J Med Mush 9 79 83 10.1615/IntJMedMushr.v9.i1.100 (Pubitemid 46573035)
33. Kerrigan RW, Wach MP (2008) Agaricus subsrufescens mushroom plant named 'H1X1'. US Patent USPP19, 313P3
34. T Koge W Komatsu K Sorimachi 2011 Heat stability of agaritine in water extracts from Agaricus blazei and other edible fungi, and removal of agaritine by ethanol fractionation Food Chem 126 1172 1177 1:CAS:528: DC%2BC3MXmtVGgsw%3D%3D 10.1016/j.foodchem.2010.11.153
35. J Kopytowski Filho MTA Minhoni AER Estrada 2006 Agaricus blazei: 'The almond Portobello' cultivation and commercialisation Mush News 54 22 28
36. J Kopytowski Filho MTA Minhoni MCN Andrade D Zied 2008 Effect of compost supplementation (soybean meal and Champfood) at different phases (spawning and before casing) on productivity of Agaricus blazei ss. Heinemann (A. brasiliensis) Mush Sci 17 260 270
37. Y Kuroiwa A Nishikawa T Imazawa K Kanki Y Kitamura T Unemura M Hirose 2005 Lack of subchronic toxicity of an aqueous extract of Agaricus blazei Murill in F344 rats Food Chem Toxicol 43 1047 1053 1:CAS:528:DC%2BD2MXjt1Sru7c%3D 10.1016/j.fct.2005.02.007
38. Laborde J, Lanzi G, Francescutti B, Giordani E (1993) Indoor composting: general principles and large development in Italy. In: Chang ST, Buswell JA, Chiu SW (eds) Mushroom biology and mushroom products. Chinese University Press, Hong Kong, pp 93-113
39. AMB Machado ES Dias EC Santos RTF Freitas 2007 Composto exaurido do cogumelo Agaricus blazei na dieta de frangos de corte Rev Bras Zootec 36 1113 1118 10.1590/S1516-35982007000500018 (Pubitemid 47358353)
40. MA Mahmud H Kitaura M Fukuda 2007 AFLP analysis for examing genetic differences in cultivated strains and their single-spore isolates and for confirming successful crosses in Agaricus blazei Mycoscience 48 297 304 1:CAS:528:DC%2BD2sXhsVCmtLnJ 10.1007/s10267-007-0372-6 (Pubitemid 47556538)
41. TRD Mantovani GA Linde NB Colauto 2007 Effect of the addition of nitrogen sources to cassava fiber and carbon-to-nitrogen ratios on Agaricus brasiliensis growth Can J Microbiol 53 139 143 1:CAS:528:DC%2BD2sXkt1ChsLc%3D 10.1139/w06-112 (Pubitemid 46640220)
42. Marques JM, Urben AF, Buso GSC (2006) Estudo de diferenças genotípicas entre indivíduos de Agaricus blazei baseado em marcadores RAPD. XI Encontro do talento estudiantil. Embrapa Recursos genéticos e biotecnologia. BR, Brasilia Univ, Brasilia, p 187
43. RG Matute D Figlas N Curvetto 2010 Sunflower seed hull based compost for Agaricus blazei Murill cultivation Int Biodeterioration Biodegradation 64 742 747 10.1016/j.ibiod.2010.08.008
44. Mendonça M, Kasuya MC, Cadorin A, Vieira AJ (2005) Agaricus blazei cultivation for a living in Brazil. Mushroom growers' handbook 2, Shiitake cultivation, Seoul, Korea, MushWorld (ed), pp.247-257
45. Minhoni MTA, Kopytowski Filho J, Andrade MCN (2005) Cultivo de Agaricus blazei Murrill ss. Heinemann. 3 rd ed rev. FEPAF, Bocatu, BR
46. T Mizuno 2000 Cultivation of the medicinal mushroom royal sun agaricus-Agaricus blazei Murr. (Agaricomycetideae) Int J Med Mushrm 2 215 220
47. T Mizuno T Hagiwara T Nakamura H Ito K Shimura T Sumiya A Asakura 1990 Antitumor activity and some properties of water-soluble polysaccharides from 'Himematsutake', the fruiting body of Agaricus blazei Murrill Agric Biol Chem 54 2889 2896 1:CAS:528:DyaK3MXjsFGltQ%3D%3D 10.1271/bbb1961.54.2889
48. JS Nascimento AF Eira 2003 Occurrence of the false truffle (Diehlomyces microsporus Gilkey) and damage on the Himematsutake medicinal mushroom (Agaricus brasiliensis S. Wasser et al.) Int J Med Mushrm 5 87 94 10.1615/ InterJMedicMush.v5.i1.100
49. JS Nascimento AF Eira 2007 Isolation and mycelial growth of Diehlomyces microsporus: effect of culture medium and incubation temperature Braz Arch Biol Technol 50 587 595 10.1590/S1516-89132007000400004 (Pubitemid 47631090)
50. MA Neves MCM Kasuya E Araújo CL Leite CM Camelini LCC Ribas MM Mendonça 2005 Physiological and genetic variability of commercial isolates of culinary-medicinal mushroom Agaricus brasiliensis S. Wasser et al. (Agaricomycetidae) cultivated in Brazil Int J Med Mushrm 7 553 563 1:CAS:528:DC%2BD28XpslWit7w%3D 10.1615/IntJMedMushr.v7.i4.50
51. ECM Oliveira ER Oliveira LCO Lima EVB Villas Boas 1999 Composição centisimal do cogumelo do sol (Agaricus blazei) R Uni Alfenas 5 169 172
52. CUJ Oliveira Lima CO de Almeida Cordova NO de Toledo SS Funghetto G de Oliveira M Karnikowski 2011 Does the Agaricus blazei Murill mushroom have properties that affect the immune system? An integrative review J Med Food 14 2 8 10.1089/jmf.2010.0017
53. SF Pascholati L Toffano MB Fialho 2007 Potential of Lentinula edodes, Agaricus blazei and Saccharomyces cerevisiae in the control of Guignardia citricarpa, the causal agent of post-harvest citrus black spot Bull OILB/SROP 30 47
54. 13C NMR. J Agric Food Chem. doi: 10.1021/jf2017622
55. LCC Ribas MM Mendoça CM Camelini CHL Soares 2009 Use of spent mushroom substrate from Agaricus subrufescens (syn. A. blazei, A. brasiliensis) and Lentinula edodes productions in the enrichment of a soil-based potting media for lettuce (Lactuva sativa) cultivation: growth promotion and soil remediation Bioresour Technol 100 4750 4757 1:CAS:528:DC%2BD1MXnvVCgsr0%3D 10.1016/j.biortech.2008.10.059
56. J-M Savoie 1998 Changes in enzyme activities during early growth of the edible mushroom, Agaricus bisporus, in compost Mycol Res 102 1113 1118 1:CAS:528:DyaK1cXmtlWhtb4%3D 10.1017/S0953756298006121 (Pubitemid 28489974)
57. CKR Shibata IM Demiate 2003 Cultivo e análise da composição química do cogumelo do sol (Agaricus blazei Murril) Publ UEPG Ci Biol Saúde 9 21 32
58. CH Shu CJ Xu 2007 Medium optimization for producing exopolysaccharides by Agaricus brasiliensis S. Wasser et al. (= A. Blazei Murill ss. Heinem) in submerged culture Food Technol Biotechnol 45 327 333 1:CAS:528: DC%2BD2sXhtFGksrnK
59. RF Silva SF Pascholati IP Bedendo 2008 Indução de resistência em plantas de berinjela por Lentinula edodes e Agaricus blazei contra Ralstonia solanacearum: aspectos bioquímicos e biomassa vegetal Summa Phytopathol 34 137 144 10.1590/S0100-54052008000200005
60. FG Siqueira ES Dias R da Silva ET Martos DL Rinker 2009 Cultivation of Agaricus blazei ss. Heinemann using different soils as source of casing materials Sci Agric 66 827 830 10.1590/S0103-90162009000600016
61. FG Siqueira AG Siqueira EG Siqueira MA Carvalho BMP Peretti PMD Jaramillo RSS Teixeira ES Dias CR Félix EXF Filho 2010 Evaluation of holocellulase production by plant-degrading fungi grown on agro-industrial residues Biodegradation 21 815 824 10.1007/s10532-010-9346-z
62. Sonnenberg ASM, Baars JJP, Hendrickx PM (2004) Retrotransposons as molecular markers in basidiomycetes. Programme and abstracts of the COST-Meeting Role of Mycorrhiza in sustainable land management. In: Baar J, Josten E (eds.) Applied Plant Research. WUR, Netherlands p. 200
63. T Stijve MALD Amazonas V Giller 2003 Characterization of flavour and taste compounds in Agaricus blazei Murill sensu Heinem., the cultivated almond mushroom Austr Mycologist 22 116 122
64. T Takadu Y Kimura H Okuda 2001 Isolation of antitumor compound from Agaricus blazei Murrill and its mechanism of action Nutritional Sci 131 1409 1413 (Pubitemid 32422958)
65. MM Tomizawa ES Dias LJ de Assi PHO Gomide JB dos Santos 2007 Genetic variability of mushroom isolates Agaricus blazei using markers rapd Ciênc Agrotec 31 1242 1249 1:CAS:528:DC%2BD1cXhvVChu78%3D 10.1590/S1413- 70542007000400045
66. SY Tsai HL Tsai JL Mau 2008 Non-volatile taste components of Agaricus blazei, Agrocybe cylindracea and Boletus edulis Food Chem 107 977 983 1:CAS:528:DC%2BD2sXhtlOisLnN 10.1016/j.foodchem.2007.07.080 (Pubitemid 350161189)
67. YH Tseng JL Mau 1999 Contents of sugars, free amino acids and free 5′-nucleotides in mushrooms, Agaricus bisporus, during postharvest storage J Sci Food Agric 79 1519 1523 1:CAS:528:DyaK1MXlt12rsr0%3D 10.1002/(SICI)1097- 0010(199908)79:11<1519::AID-JSFA399>3.0.CO;2-M (Pubitemid 29373305)
68. M Ueda KRF Schwan-Estrada AT Itako RR Oliveira BM Aguiar 2008 Extrato etanólico obtido do composto exaurido de Agaricus blazei no crescimento, esporulação e germinação in vitro de Corynespora cassiicola e na indução da enzima peroxidase em plantas de pepino 'japonês' Scientia Agraria Paranaensis 7 65 73
69. R Ullrich LM Huong NL Dung M Hofrichter 2005 Laccase from the medicinal mushroom Agaricus blazei: production, purification and characterization Appl Microbiol Biotechnol 67 357 363 1:CAS:528:DC%2BD2MXjs1Omu7c%3D 10.1007/s00253-004-1861-6 (Pubitemid 40684737)
70. JC Wang WJ Ho CH Wu 2008 Heavy metal contents of the cultivated culinary-medicinal royal sin agaricus (the Himematsutake mushroom) Agaricus brasiliensis S. Wasser et al. (Agaricomycetidae) using different casing materials Int J Med Mushrm 10 181 188 10.1615/IntJMedMushr.v10.i2.90 (Pubitemid 351549558)
71. Q Wang BB Li H Li JR Han 2010 Yield, dry matter and polysaccharides content of the mushroom Agaricus blazei produced on asparagus straw substrate Sci Hortic 125 16 18 1:CAS:528:DC%2BC3cXkvFCgt74%3D 10.1016/j.scienta.2010.02. 022
72. SP Wasser 2002 Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides Appl Microbiol Biotechnol 60 258 274 1:CAS:528:DC%2BD38XoslOrtrk%3D 10.1007/s00253-002-1076-7
73. SP Wasser MY Didukh MAL Amazonas E Nevo P Stamets AF Eira 2002 Is a widely cultivated culinary-medicinal Royal Sun Agaricus (the Himematsutake mushroom) indeed Agaricus blazei Murill? Int J Med Mushrm 4 267 290
74. SP Wasser MY Didukh MAL Amazonas E Nevo P Stamets AF Eira 2005 Is a widely cultivated culinary-medicinal Royal Sun Agaricus (Champignon do Brazil, or the Himematsutake mushroom) Agaricus brasiliensis S. Wasser et al indeed a synonym of A. subrufescens peck? Int J Med Mushrm 7 507 511 10.1615/ IntJMedMushr.v7.i3.70 (Pubitemid 43087399)
75. JH Yang HC Lin JL Mau 2001 Non-volatile taste components of several commercial mushrooms Food Chem 72 465 471 1:CAS:528:DC%2BD3MXhtV2msL8%3D 10.1016/S0308-8146(00)00262-4 (Pubitemid 32120097)
76. S Yamagushi T Yoshikawa S Ikeda T Ninomiya 1971 Measurement of the relative taste intensity of some α-amino acid and 5′-nucleotides J Food Sci 36 846 849 10.1111/j.1365-2621.1971.tb15541.x
77. LL Zaghi Junior GA Linde NB Colauto 2010 Carbon-to-nitrogen ratios for Agaricus brasiliensis on the axenic method Acta Scientiarum. Agronomy 32 55 60
78. Q Zhou X Tang Z Huang P Song J Zhou 2010 Novel method for cultivating Agaricus blazei Acta Edulis Fungi 17 29 42
79. DC Zied MTA Minhoni 2009 Influência do ambiente de cultivo na produção do cogumelo Agaricus blazei ss. Heineman (A. Brasiliensis) Energia na Agricultura 24 17 36
80. DC Zied MTA Minhoni J Kopytowski-Filho MCN Andrade 2010 Production of Agaricus blazei ss. Heinemann (A. brasiliensis) on different casing layers and environments World J Microbiol Biotechnol 26 1857 1863 10.1007/s11274-010-0367-x
81. DC Zied MTA Minhoni J Kopytowski-Filho L Barbosa MCN Andrade 2011 Medicinal mushroom growth as affected by non-axenic casing soil Pedosphere 21 146 153 1:CAS:528:DC%2BC3MXkvVyrs7Y%3D 10.1016/S1002-0160(11)60112-4
82. X Zou 2005 Effect of Zn supplementation on the growth, amino acid composition, polysaccharide yields and anti-tumour activity of Agaricus brasiliensis World J Microbiol Biotechnol 21 261 264 1:CAS:528: DC%2BD2MXmt1GnsLc%3D 10.1007/s11274-004-2614-5 (Pubitemid 41124132)
83. X Zou 2006 Fed-batch fermentation for hyperproduction of polysaccharide and ergosterol by medicinal mushroom Agaricus brasiliensis Process Biochem 41 970 974 1:CAS:528:DC%2BD28XhvVWmsLs%3D 10.1016/j.procbio.2005.10.030 (Pubitemid 43286905)