Lecithin/chitosan nanoparticles for transdermal delivery of melatonin

Journal of Microencapsulation

Volumn 28, Issue 8, 2011, Pages 807-815

  Hafner, Anita ^a   Lovrić, Jasmina ^a   Pepić, Ivan ^a   Filipović Grčić, Jelena ^a  

^a UNIVERSITY OF ZAGREB   (Croatia)

Author keywords

Chitosan; Lecithin; Melatonin; Nanoparticles; Transdermal permeability

Indexed keywords

CHITOSAN; MELATONIN; NANOPARTICLE; PHOSPHATIDYLCHOLINE; PROTEIN S 100;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG TRANSPORT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; KERATINOCYTE; NONHUMAN; PARTICLE SIZE; SKIN FIBROBLAST; SKIN PERMEABILITY; SKIN TOXICITY; SWINE; TRANSDERMAL DRUG ADMINISTRATION; ZETA POTENTIAL;

ADMINISTRATION, CUTANEOUS; ANIMALS; CELL LINE; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CHITOSAN; DRUG CARRIERS; HUMANS; LECITHINS; MELATONIN; NANOPARTICLES; SKIN; SKIN ABSORPTION; SWINE;

EID: 82255196165     PISSN: 02652048     EISSN: 14645246     Source Type: Journal    
DOI: 10.3109/02652048.2011.622053     Document Type: Article

References (44)

1. Amidi M, Romeijn SG, Borchard G, Junginger HE, Hennink WE, Jiskoot W. Preparation and characterization of protein-loaded N-trimethyl chitosan nanoparticles as nasal delivery system. J Controlled Release, 2006;111:107-16. (Pubitemid 43290000)
2. Amidi M, Romeijn SG, Verhoef JC, Junginger HE, Bungener L, Huckriede A, Crommelin DJ, Jiskoot W. N-trimethyl chitosan (TMC) nanoparticles loaded with influenza subunit antigen for intranasal vaccination: Biological properties and immunogenicity in a mouse model. Vaccine, 2007;25:144-53. (Pubitemid 44855251)
3. Baldrick P. The safety of chitosan as a pharmaceutical excipient. Regul Toxicol Pharmacol, 2010;56:290-9.
4. Bjorklund S, Engblom J, Thuresson K, Sparr E. A water gradient can be used to regulate drug transport across skin. J Controlled Release, 2010;143:191-200.
5. CarrenoGomez B, Duncan R. Evaluation of the biological properties of soluble chitosan and chitosan microspheres. Int J Pharm, 1997;148:231-40.
6. Ceraulo L, Fanara S, Liverib VT, Ruggirello A, Panzeri W, Mele A. Orientation and molecular contacts of melatonin confined into AOT and lecithin reversed micellar systems. Colloids Surf A, 2008;316:307-12. (Pubitemid 351173734)
7. Cevc G. Lipid vesicles and other colloids as drug carriers on the skin. Adv Drug Delivery Rev, 2004;56:675-711. (Pubitemid 38326939)
8. Cevc G, Vierl U. Nanotechnology and the transdermal route: A state of the art review and critical appraisal. J Controlled Release, 2010;141:277-99.
9. Chae SY, Jang MK, Nah JW. Influence of molecular weight on oral absorption of water soluble chitosans. J Controlled Release, 2005;102:383-94. (Pubitemid 40093761)
10. Dreher F, Denig N, Gabard B, Schwindt DA, Maibach HI. Effect of topical antioxidants on UV-induced erythema formation when administered after exposure. Dermatology, 1999;198:52-5. (Pubitemid 29086335)
11. Dreher F, Gabard B, Schwindt DA, Maibach HI. Topical melatonin in combination with vitamins E and C protects skin from ultraviolet-induced erythema: a human study in vivo. Br J Dermatol, 1998;139:332-9. (Pubitemid 28389414)
12. Dreher F, Maibach H. Protective effects of topical antioxidants in humans. Curr Probl Dermatol, 2001;29:157-64.
13. Dubey V, Mishra D, Asthana A, Jain NK. Transdermal delivery of a pineal hormone: Melatonin via elastic liposomes. Biomaterials, 2006;27:3491-6.
14. Dubey V, Mishra D, Jain NK. Melatonin loaded ethanolic liposomes: Physicochemical characterization and enhanced transdermal delivery. Eur J Pharm Biopharm, 2007;67:398-405. (Pubitemid 47211909)
15. Dubey V, Mishra D, Nahar M, Jain NK. Elastic liposomes mediated trans-dermal delivery of an anti-jet lag agent: Preparation, characterization and in vitro human skin transport study. Curr Drug Deliv, 2008;5:199-206. (Pubitemid 351977883)
16. Gerelli Y, Barbieri S, Di Bari MT, Deriu A, Cantu L, Brocca P, Sonvico F, Colombo P, May R, Motta S. Structure of self-organized multilayer nano-particles for drug delivery. Langmuir, 2008;24:11378-84.
17. Hafner A, Lovric J, Voinovich D, Filipovic-Grcic J. Melatonin-loaded leci-thin/chitosan nanoparticles: Physicochemical characterisation and permeability through Caco-2 cell monolayers. Int J Pharm, 2009;381:205-13.
18. He W, Guo X, Xiao L, Feng M. Study on the mechanisms of chitosan and its derivatives used as transdermal penetration enhancers. Int J Pharm, 2009;382:234-43.
19. He W, Guo X, Zhang M. Transdermal permeation enhancement of N-trimethyl chitosan for testosterone. Int J Pharm, 2008;356:82-7.
20. Jacobi U, Kaiser M, Toll R, Mangelsdorf S, Audring H, Otberg N, Sterry W, Lademann J. Porcine ear skin: An in vitro model for human skin. Skin Res Technol, 2007;13:19-24. (Pubitemid 46152448)
21. Kanikkannan N, Jackson T, Shaik MS, Singh M. Evaluation of skin sensiti-zation potential of melatonin and nimesulide by murine local lymph node assay. Eur J Pharm Sci, 2001;14:217-20. (Pubitemid 32888174)
22. Kelmann RG, Kuminek G, Teixeira HF, Koester LS. Carbamazepine paren-teral nanoemulsions prepared by spontaneous emulsification process. Int J Pharm, 2007;342:231-9. (Pubitemid 47271896)
23. Lee PW, Hsu SH, Tsai JS, Chen FR, Huang PJ, Ke CJ, Liao ZX, Hsiao CW, Lin HJ, Sung HW. Multifunctional core-shell polymeric nanoparticles for transdermal DNA delivery and epidermal Langerhans cells tracking. Biomaterials, 2010;31:2425-34.
24. Lorenz M, Saretzki G, Sitte N, Metzkow S, von Zglinicki T. BJ fibro-blasts display high antioxidant capacity and slow telomere shortening independent of hTERT transfection. Free Radic Biol Med, 2001;31:824-31. (Pubitemid 32835264)
25. Ong SY, Wu J, Moochhala SM, Tan MH, Lu J. Development of a chitosan-based wound dressing with improved haemostatic and antimicrobial properties. Biomaterials, 2008;29:4323-32.
26. Opanasopit P, Aumklad P, Kowapradit J, Ngawhiranpat T, Apirakaramwong A, Rojanarata T, Puttipipatkhachorn S. Effect of salt forms and molecular weight of chitosans on in vitro permeability enhancement in intestinal epithelial cells (Caco-2). Pharm Dev Technol, 2007;12:447-55. (Pubitemid 350034877)
27. Pavelić Z, Skalko-Basnet N, Filipović-Grcić J, Martinac A, Jalsenjak I. Development and in vitro evaluation of a liposomal vaginal delivery system for acyclovir. J Controlled Release, 2005;106:34-43.
28. Priano L, Esposti D, Esposti R, Castagna G, De Medici C, Fraschini F, Gasco MR, Mauro A. Solid lipid nanoparticles incorporating melatonin as new model for sustained oral and transdermal delivery systems. J Nanosci Nanotechnol, 2007;7:3596-601.
29. Sadeghi AM, Dorkoosh FA, Avadi MR, Weinhold M, Bayat A, Delie F, Gurny R, Larijani B, Rafiee-Tehrani M, Junginger HE. Permeation enhancer effect of chitosan and chitosan derivatives: Comparison of formulations as soluble polymers and nanoparticulate systems on insulin absorption in Caco-2 cells. Eur J Pharm Biopharm, 2008;70:270-8.
30. Santander-Ortega MJ, Stauner T, Loretz B, Ortega-Vinuesa JL, Bastos-Gonzalez D, Wenz G, Schaefer UF, Lehr CM. Nanoparticles made from novel starch derivatives for transdermal drug delivery. J Controlled Release, 2010;141:85-92.
31. Schaffazick SR, Pohlmann AR, de Cordova CA, Creczynski-Pasa TB, Guterres SS. Protective properties of melatonin-loaded nanoparticles against lipid peroxidation. Int J Pharm, 2005;289:209-13. (Pubitemid 40093555)
32. Schaffazick SR, Siqueira IR, Badejo AS, Jornada DS, Pohlmann AR, Netto CA, Guterres SS. Incorporation in polymeric nanocapsules improves the antioxidant effect of melatonin against lipid peroxidation in mice brain and liver. Eur J Pharm Biopharm, 2008;69:64-71.
33. Schubert MA, Harms M, Muller-Goymann CC. Structural investigations on lipid nanoparticles containing high amounts of lecithin. Eur J Pharm Sci, 2006;27:226-36. (Pubitemid 41831258)
34. Sekkat N, Kalia YN, Guy RH. Biophysical study of porcine ear skin in vitro and its comparison to human skin in vivo. J Pharm Sci, 2002;91:2376-81. (Pubitemid 35231200)
35. Senyigit T, Sonvico F, Barbieri S, Ozer O, Santi P, Colombo P. Lecithin/chitosan nanoparticles of clobetasol-17-propionate capable of accumulation in pig skin. J Controlled Release, 2010;142:368-73.
36. Sheihet L, Chandra P, Batheja P, Devore D, Kohn J, Michniak B. Tyrosine-derived nanospheres for enhanced topical skin penetration. Int J Pharm, 2008;350:312-9.
37. Singla AK, Chawla M. Chitosan. Some pharmaceutical and biological aspects-an update. J Pharm Pharmacol, 2001;53:1047-67. (Pubitemid 32754936)
38. Sonvico F, Cagnani A, Rossi A, Motta S, Di Bari MT, Cavatorta F, Alonso MJ, Deriu A, Colombo P. Formation of self-organized nanoparticles by lec-ithin/chitosan ionic interaction. Int J Pharm, 2006;324:67-73. (Pubitemid 44548291)
39. Tursilli R, Casolari A, Iannuccelli V, Scalia S. Enhancement of melatonin photostability by encapsulation in lipospheres. J Pharm Biomed Anal, 2006;40:910-4. (Pubitemid 43257895)
40. Ueno H, Mori T, Fujinaga T. Topical formulations and wound healing applications of chitosan. Adv Drug Delivery Rev, 2001;52:105-15. (Pubitemid 33079166)
41. Unfried K, Albrecht C, Klotz LO, Von Mikecz A, Grether-Beck S, Schins RPF. Cellular responses to nanoparticles: Target structures and mechanisms. Nanotoxicology, 2007;1:52-71. (Pubitemid 46570247)
42. Wiegand C, Hipler UC. Evaluation of biocompatibility and cytotoxicity using keratinocyte and fibroblast cultures. Skin Pharmacol Physiol, 2009;22:74-82.
43. Wiegand C, Winter D, Hipler UC. Molecular-weight-dependent toxic effects of chitosans on the human keratinocyte cell line HaCaT. Skin Pharmacol Physiol, 2010;23:164-70.
44. Williams A, 2003. Transdermal and topical drug delivery. London: Pharmaceutical Press.