Multifunctional core-shell polymeric nanoparticles for transdermal DNA delivery and epidermal Langerhans cells tracking

Biomaterials

Volumn 31, Issue 8, 2010, Pages 2425-2434

  Lee, Po Wei ^a   Hsu, Sheng Hsiang ^a   Tsai, Jin Sheng ^b   Chen, Fu Rong ^a   Huang, Pei Jai ^a   Ke, Cherng Jyh ^a   Liao, Zi Xian ^a   Hsiao, Chun Wen ^a   Lin, Hao Jan ^c   Sung, Hsing Wen ^a  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b NATIONAL SYNCHROTRON RADIATION RESEARCH CENTER   (Taiwan)

^c INSTITUTE OF PLANT AND MICROBIAL BIOLOGY   (Taiwan)

Author keywords

Cell tracking; Gene delivery; Immunotherapy; Quantum dots; Stimuli responsive materials

Indexed keywords

ANTIGEN PRESENTING CELLS; CELL TRACKING; CORE AREA; CORE SHELL STRUCTURE; CORE-SHELL; CORE-SHELL NANOPARTICLES; DNA CARRIER; DNA DELIVERY; FLUORESCENCE SPECTROPHOTOMETRY; FLUORESCENT QUANTUM DOTS; FUNCTIONAL ASPECTS; GENE DELIVERY; GENE PRODUCTS; GLYCOL CHITOSAN; IMMUNE SYSTEMS; LANGERHANS CELLS; LYMPH NODE; MOUSE MODELS; NANOPARTICLE SYSTEMS; POLYMERIC NANOPARTICLES; QUANTUM DOT; REPORTER GENE; SHELL LAYERS; STIMULI-RESPONSIVE MATERIALS; TRANSDERMAL; TRANSDERMAL DELIVERY; ULTRASENSITIVE DETECTION; VACCINE DEVELOPMENT; X-RAY DIFFRACTION MEASUREMENTS;

CYTOLOGY; DNA; DRUG THERAPY; FLUORESCENCE; GENE TRANSFER; GENES; GLYCOLS; NANOPARTICLES; SHELLS (STRUCTURES); TRANSMISSION ELECTRON MICROSCOPY; X RAY DIFFRACTION ANALYSIS;

SEMICONDUCTOR QUANTUM DOTS;

CHITOSAN; DNA; ENHANCED GREEN FLUORESCENT PROTEIN; POLYGLACTIN; QUANTUM DOT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; DNA TRANSFECTION; GENE DELIVERY SYSTEM; GENE GUN; GENE TARGETING; HUMAN; HUMAN CELL; HYDROPHOBICITY; IMMUNOTHERAPY; LANGERHANS CELL; MOUSE; NONHUMAN; PH MEASUREMENT; PRIORITY JOURNAL; REPORTER GENE; SENSITIVITY ANALYSIS; SPECTROFLUOROMETRY; SURFACE CHARGE; TRANSMISSION ELECTRON MICROSCOPY; X RAY DIFFRACTION;

ADMINISTRATION, CUTANEOUS; ANIMALS; CELLS, CULTURED; DNA; DRUG CARRIERS; EPIDERMIS; FIBROBLASTS; HUMANS; HYDROGEN-ION CONCENTRATION; LACTIC ACID; LANGERHANS CELLS; MATERIALS TESTING; MICE; NANOPARTICLES; PARTICLE SIZE; POLYGLYCOLIC ACID; POLYMERS; QUANTUM DOTS; TRANSFECTION; VACCINES, DNA;

EID: 74449084205     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.11.100     Document Type: Article

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