메뉴 건너뛰기




Volumn 69, Issue 1, 2008, Pages 64-71

Incorporation in polymeric nanocapsules improves the antioxidant effect of melatonin against lipid peroxidation in mice brain and liver

Author keywords

Brain; Lipid peroxidation; Liver; Melatonin; Polymeric nanocapsules; Total antioxidant reactivity

Indexed keywords

DICHLOROFLUORESCEIN; FREE RADICAL; LIPID; LUMINOL; MELATONIN; NANOCAPSULE; POLYSORBATE 80; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

EID: 41549088846     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2007.11.010     Document Type: Article
Times cited : (66)

References (67)
  • 3
    • 0008477161 scopus 로고    scopus 로고
    • Mechanisms of disease - melatonin in humans
    • Epstein F.H. Mechanisms of disease - melatonin in humans. N. Engl. J. Med. 336 (1997) 186-195
    • (1997) N. Engl. J. Med. , vol.336 , pp. 186-195
    • Epstein, F.H.1
  • 6
    • 0030914428 scopus 로고    scopus 로고
    • Pharmacological actions of melatonin in oxygen radical pathophysiology
    • Reiter R.J., Tang L., Garcia J.J., and Muñoz-Hoyos A. Pharmacological actions of melatonin in oxygen radical pathophysiology. Life Sci. 60 (1997) 2255-2271
    • (1997) Life Sci. , vol.60 , pp. 2255-2271
    • Reiter, R.J.1    Tang, L.2    Garcia, J.J.3    Muñoz-Hoyos, A.4
  • 7
    • 0031845040 scopus 로고    scopus 로고
    • Oxidative damage in the cerebral nervous system: protection by melatonin
    • Reiter R.J. Oxidative damage in the cerebral nervous system: protection by melatonin. Prog. Neurobiol. 56 (1998) 359-384
    • (1998) Prog. Neurobiol. , vol.56 , pp. 359-384
    • Reiter, R.J.1
  • 9
    • 0034983585 scopus 로고    scopus 로고
    • Anticarcinogenic actions of melatonin which involve antioxidative process: comparison with other antioxidants
    • Karbownik M., Lewinski A., and Reiter R.J. Anticarcinogenic actions of melatonin which involve antioxidative process: comparison with other antioxidants. Int. J. Biochem. Cell Biol. 33 (2001) 735-753
    • (2001) Int. J. Biochem. Cell Biol. , vol.33 , pp. 735-753
    • Karbownik, M.1    Lewinski, A.2    Reiter, R.J.3
  • 10
    • 0037198063 scopus 로고    scopus 로고
    • Reactive oxygen and nitrogen species and cellular and organismal decline: amelioration with melatonin
    • Reiter R.J., Tan D.-X., and Burkhardt S. Reactive oxygen and nitrogen species and cellular and organismal decline: amelioration with melatonin. Mech. Ageing Dev. 123 (2002) 1007-1019
    • (2002) Mech. Ageing Dev. , vol.123 , pp. 1007-1019
    • Reiter, R.J.1    Tan, D.-X.2    Burkhardt, S.3
  • 13
    • 23044488162 scopus 로고    scopus 로고
    • Melatonin ameliorates carbon tetrachloride-induced hepatic fibrogenesis in rats via inhibition of oxidative stress
    • Wang H., Wei W., Wang N.-P., Gui S.-Y., Wu L., Sun W.-Y., and Xu S.-Y. Melatonin ameliorates carbon tetrachloride-induced hepatic fibrogenesis in rats via inhibition of oxidative stress. Life Sci. 77 (2005) 1902-1915
    • (2005) Life Sci. , vol.77 , pp. 1902-1915
    • Wang, H.1    Wei, W.2    Wang, N.-P.3    Gui, S.-Y.4    Wu, L.5    Sun, W.-Y.6    Xu, S.-Y.7
  • 14
    • 34247151073 scopus 로고    scopus 로고
    • Melatonin: therapeutic and clinic utilization
    • Altun A., and Ugur-Altun B. Melatonin: therapeutic and clinic utilization. Int. J. Clin. Pract. 61 (2007) 835-845
    • (2007) Int. J. Clin. Pract. , vol.61 , pp. 835-845
    • Altun, A.1    Ugur-Altun, B.2
  • 15
    • 0037378182 scopus 로고    scopus 로고
    • The utility of melatonin in reducing cerebral damage resulting from ischemia and reperfusion
    • Cheung R.T.F. The utility of melatonin in reducing cerebral damage resulting from ischemia and reperfusion. J. Pineal Res. 34 (2003) 153-160
    • (2003) J. Pineal Res. , vol.34 , pp. 153-160
    • Cheung, R.T.F.1
  • 17
    • 0346848865 scopus 로고    scopus 로고
    • Nanotech approaches to drug delivery and imaging
    • Sahoo S.K., and Labhasetwar V. Nanotech approaches to drug delivery and imaging. Drug Discov. Today 8 (2003) 1112-1120
    • (2003) Drug Discov. Today , vol.8 , pp. 1112-1120
    • Sahoo, S.K.1    Labhasetwar, V.2
  • 18
    • 21344451667 scopus 로고    scopus 로고
    • Colloidal carriers and blood-brain barrier (BBB) translocation: a way to deliver drugs to the brain?
    • Garcia-Garcia E., Andrieux K., Gil S., and Couvreur P. Colloidal carriers and blood-brain barrier (BBB) translocation: a way to deliver drugs to the brain?. Int. J. Pharm. 298 (2005) 274-292
    • (2005) Int. J. Pharm. , vol.298 , pp. 274-292
    • Garcia-Garcia, E.1    Andrieux, K.2    Gil, S.3    Couvreur, P.4
  • 19
    • 0141794568 scopus 로고    scopus 로고
    • Caracterização e estabilidade fi{dotless}́sico-qui{dotless}́mica de sistemas poliméricos nanoparticulados para administração de fármacos
    • Schaffazick S.R., Guterres S.S., Lucca-Freitas L., and Pohlmann A.R. Caracterização e estabilidade fi{dotless}́sico-qui{dotless}́mica de sistemas poliméricos nanoparticulados para administração de fármacos. Quim. Nova 26 (2003) 726-737
    • (2003) Quim. Nova , vol.26 , pp. 726-737
    • Schaffazick, S.R.1    Guterres, S.S.2    Lucca-Freitas, L.3    Pohlmann, A.R.4
  • 21
    • 14844303762 scopus 로고    scopus 로고
    • Development and characterization of PLGA nanospheres and nanocapsules containing xanthone and 3-methoxyxanthone
    • Teixeira M., Alonso M.J., Pinto M.M.M., and Barbosa C.M. Development and characterization of PLGA nanospheres and nanocapsules containing xanthone and 3-methoxyxanthone. Eur. J. Pharm. Biopharm. 59 (2005) 491-500
    • (2005) Eur. J. Pharm. Biopharm. , vol.59 , pp. 491-500
    • Teixeira, M.1    Alonso, M.J.2    Pinto, M.M.M.3    Barbosa, C.M.4
  • 22
    • 0141830659 scopus 로고    scopus 로고
    • Polymeric nano- and microparticles for the oral delivery of peptides and peptidomimetics
    • Allémann E., Leroux J.-C., and Gurny R. Polymeric nano- and microparticles for the oral delivery of peptides and peptidomimetics. Adv. Drug Deliv. Rev. 34 (1998) 171-189
    • (1998) Adv. Drug Deliv. Rev. , vol.34 , pp. 171-189
    • Allémann, E.1    Leroux, J.-C.2    Gurny, R.3
  • 23
    • 0034949203 scopus 로고    scopus 로고
    • Gastro-intestinal tolerance following oral administration of spray-dried diclofenac-loaded nanocapsules and nanospheres
    • Guterres S.S., Muller C.R., Michalowski C.B., Pohlmann A.R., and Dalla Costa T. Gastro-intestinal tolerance following oral administration of spray-dried diclofenac-loaded nanocapsules and nanospheres. S.T.P. Pharma Sci. 11 (2001) 229-233
    • (2001) S.T.P. Pharma Sci. , vol.11 , pp. 229-233
    • Guterres, S.S.1    Muller, C.R.2    Michalowski, C.B.3    Pohlmann, A.R.4    Dalla Costa, T.5
  • 24
    • 0242320526 scopus 로고    scopus 로고
    • Freeze-drying polymeric colloidal suspensions: nanocapsules, nanospheres and nanodispersion. A comparative study
    • Schaffazick S.R., Pohlmann A.R., Dalla-Costa T., and Guterres S.S. Freeze-drying polymeric colloidal suspensions: nanocapsules, nanospheres and nanodispersion. A comparative study. Eur. J. Pharm. Biopharm. 56 (2003) 501-505
    • (2003) Eur. J. Pharm. Biopharm. , vol.56 , pp. 501-505
    • Schaffazick, S.R.1    Pohlmann, A.R.2    Dalla-Costa, T.3    Guterres, S.S.4
  • 27
    • 33645758753 scopus 로고    scopus 로고
    • Sustained release nanoparticulate formulation containing antioxidant-ellagic acid as potential prophylaxis system for oral administration
    • Bala I., Bhardwaj V., Hariharan S., Kharade S.V., Roy N., and Kumar M.N.V.R. Sustained release nanoparticulate formulation containing antioxidant-ellagic acid as potential prophylaxis system for oral administration. J. Drug Target. 14 (2006) 27-34
    • (2006) J. Drug Target. , vol.14 , pp. 27-34
    • Bala, I.1    Bhardwaj, V.2    Hariharan, S.3    Kharade, S.V.4    Roy, N.5    Kumar, M.N.V.R.6
  • 28
    • 0036147315 scopus 로고    scopus 로고
    • Improved antioxidant effect of idebenone-loaded polyethyl-2 cyanoacrylate nanocapsules tested on human fibroblasts
    • Palumbo M., Russo A., Cardile V., Renis M., Paolino D., Puglisi G., and Fresta M. Improved antioxidant effect of idebenone-loaded polyethyl-2 cyanoacrylate nanocapsules tested on human fibroblasts. Pharm. Res. 19 (2002) 71-78
    • (2002) Pharm. Res. , vol.19 , pp. 71-78
    • Palumbo, M.1    Russo, A.2    Cardile, V.3    Renis, M.4    Paolino, D.5    Puglisi, G.6    Fresta, M.7
  • 30
    • 23944454854 scopus 로고    scopus 로고
    • Nanosphere-mediated delivery of vitamin E increases its efficacy against oxidative stress resulting from exposure to amyloid beta
    • Shea T.B., Ortiz D., Nicolosi R.J., Kumar R., and Watterson A.C. Nanosphere-mediated delivery of vitamin E increases its efficacy against oxidative stress resulting from exposure to amyloid beta. J. Alzheimers Dis. 7 (2005) 297-301
    • (2005) J. Alzheimers Dis. , vol.7 , pp. 297-301
    • Shea, T.B.1    Ortiz, D.2    Nicolosi, R.J.3    Kumar, R.4    Watterson, A.C.5
  • 31
    • 0033993565 scopus 로고    scopus 로고
    • Increase of the duration of the anticonvulsive activity of a novel NMDA receptor antagonist using poly(butylcyanoacrylate) nanoparticles as a parenteral controlled release system
    • Friese A., Seiller E., Quack G., Lorenz B., and Kreuter J. Increase of the duration of the anticonvulsive activity of a novel NMDA receptor antagonist using poly(butylcyanoacrylate) nanoparticles as a parenteral controlled release system. Eur. J. Pharm. Biopharm. 49 (2000) 103-109
    • (2000) Eur. J. Pharm. Biopharm. , vol.49 , pp. 103-109
    • Friese, A.1    Seiller, E.2    Quack, G.3    Lorenz, B.4    Kreuter, J.5
  • 32
    • 33646460828 scopus 로고    scopus 로고
    • Application of nanoparticles for the delivery of drugs to the brain
    • Kreuter J. Application of nanoparticles for the delivery of drugs to the brain. Int. Congr. Ser. 1277 (2005) 85-94
    • (2005) Int. Congr. Ser. , vol.1277 , pp. 85-94
    • Kreuter, J.1
  • 33
    • 0343267787 scopus 로고    scopus 로고
    • Nanoparticles, a drug carrier system to pass the blood-brain barrier, permit central analgesic effects of i.v. dalargin injections
    • Schröder U., and Sabel B.A. Nanoparticles, a drug carrier system to pass the blood-brain barrier, permit central analgesic effects of i.v. dalargin injections. Brain Res. 710 (1996) 121-124
    • (1996) Brain Res. , vol.710 , pp. 121-124
    • Schröder, U.1    Sabel, B.A.2
  • 34
    • 0030853702 scopus 로고    scopus 로고
    • Influence of the type of surfactant on the analgesic effects induced by the peptide dalargin after its delivery across the blood-brain barrier using surfactant-coated nanoparticles
    • Kreuter J., Petrov V.E., Kharkevich D.A., and Alyautdin R.N. Influence of the type of surfactant on the analgesic effects induced by the peptide dalargin after its delivery across the blood-brain barrier using surfactant-coated nanoparticles. J. Control. Release 49 (1997) 81-87
    • (1997) J. Control. Release , vol.49 , pp. 81-87
    • Kreuter, J.1    Petrov, V.E.2    Kharkevich, D.A.3    Alyautdin, R.N.4
  • 35
  • 36
    • 0033427851 scopus 로고    scopus 로고
    • Indirect evidence that drug brain targeting using polysorbate-80-coated polybutylcyanoacrylate nanoparticles is related to toxicity
    • Olivier J.-C., Fenart L., Chauvet R., Pariat C., Cecchelli R., and Couet W. Indirect evidence that drug brain targeting using polysorbate-80-coated polybutylcyanoacrylate nanoparticles is related to toxicity. Pharm. Res. 16 (1999) 1836-1842
    • (1999) Pharm. Res. , vol.16 , pp. 1836-1842
    • Olivier, J.-C.1    Fenart, L.2    Chauvet, R.3    Pariat, C.4    Cecchelli, R.5    Couet, W.6
  • 37
    • 0033649767 scopus 로고    scopus 로고
    • 3H-labelled dalargin bound to poly(butyl cyanoacrylate) nanoparticles after i.v. injections to mice
    • 3H-labelled dalargin bound to poly(butyl cyanoacrylate) nanoparticles after i.v. injections to mice. Life Sci. 66 (2000) 495-502
    • (2000) Life Sci. , vol.66 , pp. 495-502
    • Schroeder, U.1    Schroeder, H.2    Sabel, B.A.3
  • 38
    • 0037168963 scopus 로고    scopus 로고
    • Toxicological studies of doxorubicin bound to polysorbate 80-coated poly(butyl cyanoacrylate) nanoparticles in healthy rats and rats with intracranial glioblastoma
    • Gelperina S.E., Khalansky A.S., Skidan I.N., Smirnova Z.S., Bobruskin A.I., Severin S.E., Turowski B., Zanella F.E., and Kreuter J. Toxicological studies of doxorubicin bound to polysorbate 80-coated poly(butyl cyanoacrylate) nanoparticles in healthy rats and rats with intracranial glioblastoma. Toxicol. Lett. 126 (2002) 131-141
    • (2002) Toxicol. Lett. , vol.126 , pp. 131-141
    • Gelperina, S.E.1    Khalansky, A.S.2    Skidan, I.N.3    Smirnova, Z.S.4    Bobruskin, A.I.5    Severin, S.E.6    Turowski, B.7    Zanella, F.E.8    Kreuter, J.9
  • 39
    • 0037335187 scopus 로고    scopus 로고
    • Direct Evidence that polysorbate-80-coated poly(butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drug to the nanoparticles
    • Kreuter J., Ramge P., Petrov V., Hamm S., Gelperina S.E., Engelhardt B., Alyautdin R., von Briesen H., and Begley D.J. Direct Evidence that polysorbate-80-coated poly(butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drug to the nanoparticles. Pharm. Res. 20 (2003) 409-416
    • (2003) Pharm. Res. , vol.20 , pp. 409-416
    • Kreuter, J.1    Ramge, P.2    Petrov, V.3    Hamm, S.4    Gelperina, S.E.5    Engelhardt, B.6    Alyautdin, R.7    von Briesen, H.8    Begley, D.J.9
  • 40
    • 1142309721 scopus 로고    scopus 로고
    • Specific role of polysorbate 80 coating on the targeting of nanoparticles to the brain
    • Sun W., Xie C., Wang H., and Hu Y. Specific role of polysorbate 80 coating on the targeting of nanoparticles to the brain. Biomaterials 25 (2004) 3065-3071
    • (2004) Biomaterials , vol.25 , pp. 3065-3071
    • Sun, W.1    Xie, C.2    Wang, H.3    Hu, Y.4
  • 41
    • 33344460518 scopus 로고    scopus 로고
    • Influence of particle size on transport of methotrexate across blood brain barrier by polysorbate 80-coated polybutylcyanoacrylate nanoparticles
    • Gao K., and Jiang X. Influence of particle size on transport of methotrexate across blood brain barrier by polysorbate 80-coated polybutylcyanoacrylate nanoparticles. Int. Pharm. 310 (2006) 213-219
    • (2006) Int. Pharm. , vol.310 , pp. 213-219
    • Gao, K.1    Jiang, X.2
  • 44
    • 33744730305 scopus 로고    scopus 로고
    • Development of nanocapsule suspensions and nanocapsule spray-dried powders containing melatonin
    • Schaffazick S.R., Pohlmann A.R., Mezzalira G., and Guterres S.S. Development of nanocapsule suspensions and nanocapsule spray-dried powders containing melatonin. J. Braz. Chem. Soc. 17 (2006) 562-569
    • (2006) J. Braz. Chem. Soc. , vol.17 , pp. 562-569
    • Schaffazick, S.R.1    Pohlmann, A.R.2    Mezzalira, G.3    Guterres, S.S.4
  • 45
    • 0024457576 scopus 로고
    • Nanocapsule formation by interfacial polymer deposition following solvent displacement
    • Fessi H., Puisieux F., Devissaguet J.-P., Ammoury N., and Benita S. Nanocapsule formation by interfacial polymer deposition following solvent displacement. Int. J. Pharm. 55 (1989) r1-r4
    • (1989) Int. J. Pharm. , vol.55
    • Fessi, H.1    Puisieux, F.2    Devissaguet, J.-P.3    Ammoury, N.4    Benita, S.5
  • 46
    • 0036741553 scopus 로고    scopus 로고
    • Spray-dried indometacin-loaded polyester nanocapsules and nanospheres: development, stability evaluation and nanostructure models
    • Pohlmann A.R., Weiss V., Mertins O., Pesce da Silveira N., and Guterres S.S. Spray-dried indometacin-loaded polyester nanocapsules and nanospheres: development, stability evaluation and nanostructure models. Eur. J. Pharm. Sci. 16 (2002) 305-312
    • (2002) Eur. J. Pharm. Sci. , vol.16 , pp. 305-312
    • Pohlmann, A.R.1    Weiss, V.2    Mertins, O.3    Pesce da Silveira, N.4    Guterres, S.S.5
  • 47
    • 0017872475 scopus 로고
    • Microssomal lipid peroxidation
    • Buege J.A., and Aust S.D. Microssomal lipid peroxidation. Methods Enzymol. 52 (1978) 302-310
    • (1978) Methods Enzymol. , vol.52 , pp. 302-310
    • Buege, J.A.1    Aust, S.D.2
  • 48
    • 27644596252 scopus 로고    scopus 로고
    • Aging affects oxidative state in hippocampus, hypothalamus and adrenal glands of Wistar rats
    • Siqueira I.R., Fochesatto C., da Silva Torres I.L., Dalmaz C., and Netto C.A. Aging affects oxidative state in hippocampus, hypothalamus and adrenal glands of Wistar rats. Life Sci. 78 (2005) 271-278
    • (2005) Life Sci. , vol.78 , pp. 271-278
    • Siqueira, I.R.1    Fochesatto, C.2    da Silva Torres, I.L.3    Dalmaz, C.4    Netto, C.A.5
  • 49
    • 0027015035 scopus 로고
    • Luminol luminescence induced by 2,2′-Azo-bis(2-amidinopropane) thermolysis
    • Lissi E., Pascual C., and del Castillo M.D. Luminol luminescence induced by 2,2′-Azo-bis(2-amidinopropane) thermolysis. Free Radic. Res. Commun. 17 (1992) 299-311
    • (1992) Free Radic. Res. Commun. , vol.17 , pp. 299-311
    • Lissi, E.1    Pascual, C.2    del Castillo, M.D.3
  • 50
    • 0028837204 scopus 로고
    • Evaluation of total antioxidant potential (TRAP) and total antioxidant reactivity from luminol-enhanced chemiluminescence measurements
    • Lissi E., Salim-Hanna M., Pascual C., and del Castillo M.D. Evaluation of total antioxidant potential (TRAP) and total antioxidant reactivity from luminol-enhanced chemiluminescence measurements. Free Radic. Biol. Med. 18 (1995) 153-158
    • (1995) Free Radic. Biol. Med. , vol.18 , pp. 153-158
    • Lissi, E.1    Salim-Hanna, M.2    Pascual, C.3    del Castillo, M.D.4
  • 51
    • 0034603580 scopus 로고    scopus 로고
    • Age-related in reactive oxygen species production in rat brain homogenates
    • Driver A.S., Kodavanti P.R.S., and Mundy W.R. Age-related in reactive oxygen species production in rat brain homogenates. Neurotoxicol. Teratol. 22 (2000) 175-181
    • (2000) Neurotoxicol. Teratol. , vol.22 , pp. 175-181
    • Driver, A.S.1    Kodavanti, P.R.S.2    Mundy, W.R.3
  • 52
    • 0031036391 scopus 로고    scopus 로고
    • Evidence for generation of oxidative stress in brain by MPTP: in vitro and in vivo studies in mice
    • Sriram K., Pai K.S., Boyd M.R., and Ravindranath V. Evidence for generation of oxidative stress in brain by MPTP: in vitro and in vivo studies in mice. Brain Res. 749 (1997) 44-52
    • (1997) Brain Res. , vol.749 , pp. 44-52
    • Sriram, K.1    Pai, K.S.2    Boyd, M.R.3    Ravindranath, V.4
  • 54
    • 0025300990 scopus 로고
    • Modification on the body distribution of poly(methylmethacrylate) nanoparticles in rats by coating with surfactants
    • Tröster S.D., Müller U., and Kreuter J. Modification on the body distribution of poly(methylmethacrylate) nanoparticles in rats by coating with surfactants. Int. J. Pharm. 61 (1990) 85-100
    • (1990) Int. J. Pharm. , vol.61 , pp. 85-100
    • Tröster, S.D.1    Müller, U.2    Kreuter, J.3
  • 55
    • 0035937595 scopus 로고    scopus 로고
    • Nanoparticulate systems for brain delivery of drugs
    • Kreuter J. Nanoparticulate systems for brain delivery of drugs. Adv. Drug Deliv. Rev. 47 (2001) 65-81
    • (2001) Adv. Drug Deliv. Rev. , vol.47 , pp. 65-81
    • Kreuter, J.1
  • 56
    • 0032897017 scopus 로고    scopus 로고
    • In vivo performance of parenteral theophylline-loaded polyisobutylcyanoacrylate nanoparticles in rats
    • Radwan M.A., Zaghloul I.Y., and Aly Z.H. In vivo performance of parenteral theophylline-loaded polyisobutylcyanoacrylate nanoparticles in rats. Eur. J. Pharm. Sci. 8 (1999) 95-98
    • (1999) Eur. J. Pharm. Sci. , vol.8 , pp. 95-98
    • Radwan, M.A.1    Zaghloul, I.Y.2    Aly, Z.H.3
  • 58
    • 0037246648 scopus 로고    scopus 로고
    • Inhibitory effects of melatonin on neural lipid peroxidation induced by intracerebroventricularly administered homocysteine
    • Baydas G., Kutlu S., Naziroglu M., Canpolat S., Sandal S., Ozcan M., and Kelestimur H. Inhibitory effects of melatonin on neural lipid peroxidation induced by intracerebroventricularly administered homocysteine. J. Pineal Res. 34 (2003) 36-39
    • (2003) J. Pineal Res. , vol.34 , pp. 36-39
    • Baydas, G.1    Kutlu, S.2    Naziroglu, M.3    Canpolat, S.4    Sandal, S.5    Ozcan, M.6    Kelestimur, H.7
  • 59
    • 23744457490 scopus 로고    scopus 로고
    • Melatonin reduces oxidative stress and increases gene expression in the cerebral cortex and cerebellum of aluminum-exposed rats
    • Esparza J.L., Gómez M., Nogués M.R., Paternain L., Mallol J., and Domingo J.L. Melatonin reduces oxidative stress and increases gene expression in the cerebral cortex and cerebellum of aluminum-exposed rats. J. Pineal Res. 39 (2005) 129-136
    • (2005) J. Pineal Res. , vol.39 , pp. 129-136
    • Esparza, J.L.1    Gómez, M.2    Nogués, M.R.3    Paternain, L.4    Mallol, J.5    Domingo, J.L.6
  • 60
    • 19344377507 scopus 로고    scopus 로고
    • Protective effects of melatonin against ethanol-induced reactive gliosis in hippocampus and cortex of young and aged rats
    • Baydas G., and Tuzcu M. Protective effects of melatonin against ethanol-induced reactive gliosis in hippocampus and cortex of young and aged rats. Exp. Neurol. 194 (2005) 175-181
    • (2005) Exp. Neurol. , vol.194 , pp. 175-181
    • Baydas, G.1    Tuzcu, M.2
  • 61
    • 27744598886 scopus 로고    scopus 로고
    • Comparison of the impact of melatonin on chronic ethanol-induced learning and memory impairment between young and aged rats
    • Baydas G., Yasar A., and Tuzcu M. Comparison of the impact of melatonin on chronic ethanol-induced learning and memory impairment between young and aged rats. J. Pineal Res. 39 (2005) 346-352
    • (2005) J. Pineal Res. , vol.39 , pp. 346-352
    • Baydas, G.1    Yasar, A.2    Tuzcu, M.3
  • 63
    • 0030929407 scopus 로고    scopus 로고
    • Melatonin protects against lipid peroxidation induced by δ-aminolevulinic acid in rat cerebellum, cortex and hippocampus
    • Carneiro R.C.G., and Reiter R.J. Melatonin protects against lipid peroxidation induced by δ-aminolevulinic acid in rat cerebellum, cortex and hippocampus. Neuroscience 82 (1998) 293-299
    • (1998) Neuroscience , vol.82 , pp. 293-299
    • Carneiro, R.C.G.1    Reiter, R.J.2
  • 64
    • 20444488772 scopus 로고    scopus 로고
    • Protective role of melatonin in cyclosporine A-induced oxidative stress in rat liver
    • Rezzani R., Buffoli B., Rodella L., Stacchiotti A., and Bianchi R. Protective role of melatonin in cyclosporine A-induced oxidative stress in rat liver. Int. Immunopharmacol. 5 (2005) 1397-1405
    • (2005) Int. Immunopharmacol. , vol.5 , pp. 1397-1405
    • Rezzani, R.1    Buffoli, B.2    Rodella, L.3    Stacchiotti, A.4    Bianchi, R.5
  • 65
    • 17644389906 scopus 로고    scopus 로고
    • Role of melatonin in reducing water avoidance stress-induced degeneration of the liver
    • Contuk G., Ercan F., Çetinel S., Çikler E., and Sener G. Role of melatonin in reducing water avoidance stress-induced degeneration of the liver. Dig. Dis. Sci. 50 (2005) 738-744
    • (2005) Dig. Dis. Sci. , vol.50 , pp. 738-744
    • Contuk, G.1    Ercan, F.2    Çetinel, S.3    Çikler, E.4    Sener, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.