Limited Therapeutic Effect of N-Acetylcysteine on Hepatic Insulin Resistance in an Experimental Model of Alcohol-Induced Steatohepatitis

Alcoholism: Clinical and Experimental Research

Volumn 35, Issue 12, 2011, Pages 2139-2151

  Setshedi, Mashiko ^a,c   Longato, Lisa ^b   Petersen, Dennis R ^d   Ronis, Martin ^e   Chen, William C ^a   Wands, Jack R ^a,b   De la Monte, Suzanne M ^a,b  

^a BROWN UNIVERSITY   (United States)

^b BROWN UNIVERSITY   (United States)

^c UNIVERSITY OF CAPE TOWN   (South Africa)

^d UNIVERSITY OF COLORADO   (United States)

^e UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Antioxidants; Ceramides; Ethanol; GM3 Ganglioside; Hepatic Steatosis; Insulin Resistance; Lipotoxicity; Oxidative Stress; Steatohepatitis; Total Enteral Nutrition

Indexed keywords

ACETYLCYSTEINE; ALCOHOL; CERAMIDE; GANGLIOSIDE GM3; GLYCOGEN SYNTHASE KINASE 3; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; LIPID; PROTEIN KINASE B; S6 KINASE; SOMATOMEDIN B; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; SPHINGOMYELIN PHOSPHODIESTERASE; TRIACYLGLYCEROL;

ALCOHOL CONSUMPTION; ALCOHOLIC FATTY LIVER; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALORIC INTAKE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; ENZYME ACTIVITY; GENE EXPRESSION; HEPATITIS; HISTOPATHOLOGY; INSULIN RESISTANCE; LIPID STORAGE; LIPOTOXICITY; LIVER; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; THERAPY EFFECT;

ACETYLCYSTEINE; ALCOHOLISM; ANIMALS; CYTOKINES; DISEASE MODELS, ANIMAL; FATTY LIVER, ALCOHOLIC; INSULIN RESISTANCE; MALE; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 81855221836     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2011.01569.x     Document Type: Article

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