Chronic alcohol consumption disrupted cholesterol homeostasis in rats: Down-regulation of low-density lipoprotein receptor and enhancement of cholesterol biosynthesis pathway in the liver

Alcoholism: Clinical and Experimental Research

Volumn 34, Issue 3, 2010, Pages 471-478

  Wang, Zhigang ^a,b   Yao, Tong ^a   Song, Zhenyuan ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Alcohol; Cholesterol; Extracellular Signal Regulated Kinase; Liver; Low Density Lipoprotein Receptor; Proprotein Convertase Subtilisin Kexin Type 9; Sterol Regulatory Element Binding Protein 2

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; ASPARTATE AMINOTRANSFERASE; CHOLESTEROL; DEXTRIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; KEXIN; LOW DENSITY LIPOPROTEIN RECEPTOR; MALTOSE; MITOGEN ACTIVATED PROTEIN KINASE; PROPROTEIN CONVERTING SUBTILISIN KEXIN TYPE 9; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBOHYDRATE INTAKE; CHOLESTEROL LIVER LEVEL; CHOLESTEROL METABOLISM; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME INACTIVATION; FAT INTAKE; FATTY LIVER; HUMAN; HUMAN CELL; HYPERCHOLESTEROLEMIA; IN VITRO STUDY; LIPID LIVER LEVEL; LIVER INJURY; LIVER LEVEL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN INTAKE; PROTEIN PROCESSING; PROTEIN SYNTHESIS INHIBITION; RAT;

ALCOHOL DRINKING; ANIMALS; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CHOLESTEROL; DOWN-REGULATION; ETHANOL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HOMEOSTASIS; HYPERCHOLESTEROLEMIA; LIPID METABOLISM; LIVER; LIVER DISEASES, ALCOHOLIC; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, LDL; SERINE ENDOPEPTIDASES;

RATTUS;

EID: 77749295129     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2009.01111.x     Document Type: Article

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