Multichannel liquid chromatography-tandem mass spectrometry cocktail method for comprehensive substrate characterization of multidrug resistance-associated protein 4 transporter

Pharmaceutical Research

Volumn 24, Issue 12, 2007, Pages 2281-2296

  Uchida, Yasuo ^a   Kamiie, Junichi ^a,b   Ohtsuki, Sumio ^a,b   Terasaki, Tetsuya ^a,b  

^a TOHOKU UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

ATP binding cassette transporter; Human multidrug resistance associated protein 4; Liquid chromatography tandem mass spectrometry; Substrate screening; Vesicle uptake study

Indexed keywords

ABC TRANSPORTER; ALACEPRIL; ALLOPURINOL; AMPICILLIN; BACLOFEN; BEZAFIBRATE; BUMETANIDE; CEFMETAZOLE; CEFTAZIDIME; CEPHALOSPORIN C; ENALAPRIL; FUROSEMIDE; GLUTAMIC ACID; GLUTAMINE; HYDROCHLOROTHIAZIDE; MELOXICAM; MULTIDRUG RESISTANCE PROTEIN 4; NATEGLINIDE; PENICILLIN G; PIPEMIDIC ACID; PIPERACILLIN; PRAVASTATIN; REBAMIPIDE; SALICYLIC ACID; SULBACTAM; TETRACYCLINE; THEOBROMINE; THEOPHYLLINE; TRANEXAMIC ACID; UNINDEXED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG PROTEIN BINDING; DRUG SCREENING; DRUG TRANSPORT; DRUG UPTAKE; ENZYME SUBSTRATE COMPLEX; HUMAN; LIQUID CHROMATOGRAPHY; MEMBRANE VESICLE; PRIORITY JOURNAL; PROTEIN TRANSPORT; TANDEM MASS SPECTROMETRY;

BIOLOGICAL TRANSPORT; CELL LINE; CELL MEMBRANE; CEPHAMYCINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; KINETICS; METHOTREXATE; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; OSMOTIC PRESSURE; PHARMACEUTICAL PREPARATIONS; TANDEM MASS SPECTROMETRY; TECHNOLOGY, PHARMACEUTICAL; TRANSFECTION;

EID: 35948934719     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-007-9453-7     Document Type: Article

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