Amino acids and their transporters in the retina

Neurochemistry International

Volumn 38, Issue 6, 2001, Pages 463-484

  Pow, David V ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; EPITOPE;

AMINO ACID TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; RETINA; RETINA BLOOD FLOW; REVIEW; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

AMINO ACID TRANSPORT SYSTEMS; AMINO ACIDS; ANIMALS; CARRIER PROTEINS; HUMANS; RETINA;

MAMMALIA;

EID: 0035102496     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-0186(00)00114-5     Document Type: Review

References (191)

1. (3H)-muscimol, (3H)-nipecotic acid and (3H)-isoguvacine as autoradiographic markers for GABA neurotransmission
2. Transporter-mediated GABA release induced by excitatory amino acid agonist is associated with GAD-67 but not GAD-65 immunoreactive cells of the primate retina
3. Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex
4. Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance
5. L-proline depolarized rat spinal motoneurons by an excitatory amino acid antagonist-sensitive mechanism
6. Taurine blocks spontaneous cone contraction but not horizontal cell dark suppression in isolated goldfish retina
7. Displaced amacrine and ganglion cells in the newt retina
8. Electrogenic uptake of glutamate and aspartate into glial cells isolated from the salamander Ambystoma retina
9. Antisense knockdown of GLAST, a Glial Glutamate Transporter, compromises retinal function
10. Inhibition of Müller cell glutamine synthetase rapidly impairs the retinal response to light
11. Glutamate and GABA in retinal circuitry
12. Modulation of N-methyl-D-aspartate receptor function by glycine transport
13. Glutamate is transported across the rat blood-brain barrier by a sodium-independent system
14. Anion conductance behavior of the glutamate uptake carrier in salamander retinal glial cells
15. Synaptosomal transport of radiolabel from N-acetyl-aspartyl-[3H]glutamate suggests a mechanism of inactivation of an excitatory neuropeptide
16. Hydrolysis of the brain dipeptide N-acetyl-L-aspartyl-L-glutamate, subcellular and regional distribution, ontogeny, and the effect of lesions on N-acetylated-alpha-linked acidic dipeptidase activity
17. Differential localization of radioactive gamma-aminobutyric acid and muscimol in isolated and in vivo mouse retina
18. Actin and localization of glycine and taurine in the cat retina
19. Molecular heterogeneity of the gamma-aminobutyric acid GABA. Transport system. Cloning of two novel high affinity GABA transporters from rat brain
20. Cloning and expression of a betaine/GABA transporter from human brain
21. Analysis of a gene encoding two glycine transporter variants reveals alternative promoter usage and a novel gene structure
22. Two glycine transporter variants with distinct localization in the CNS and peripheral tissues are encoded by a common gene
23. Electrogenic uptake of sulphur-containing analogues of glutamate and aspartate by Müller cells from the salamander retina
24. Parallel processing in the mammalian retina, the Proctor Lecture
25. Displaced starburst amacrine cells of the rabbit retina contain the 67-kDa isoform, but not the 65-kDa isoform, of glutamate decarboxylase
26. Xpression of GAT-1, a high-affinity gamma-aminobutyric acid plasma membrane transporter in the rat retina
27. Cellular distribution of L-glutamate decarboxylase GAD. And gamma-aminobutyric acidA GABAA. Receptor mRNAs in the retina
28. Uptake of the putative neurotransmitter, glycine, into the rabbit retina
29. Uptake of certain possible neurotransmitters into retinal neurons of some mammals
30. Effects of picrotoxin and strychnine on rabbit retinal ganglion cells, lateral interactions for cells with more complex receptive fields
31. Accumulation of 3H glycine by cone bipolar neurons in the cat retina
32. Inhibition of the high-affinity brain glutamate transporter GLAST-1 via direct phosphorylation
33. Glutamate immunoreactivity in rat cerebral cortex is reversibly abolished by 6-diazo-5-oxo-L-norleucine DON., an inhibitor of phosphate-activated glutaminase
34. GABA uptake and release by a mammalian cell line stably expressing a cloned rat brain GABA transporter
35. L-arginine uptake and release by cultured avian retinal cells, differential cellular localization in relation to nitric oxide synthase
36. Localization of the brain-specific high-affinity l-proline transporter in cultured hippocampal neurons, molecular heterogeneity of synaptic terminals
37. Localization and release of hmocystreic acid, an excitatory sulfur-containing amino acid
38. Effect of gamma-aminobutyric acid agonists, glycine, taurine and neuropeptides on acetylcholine release from the rabbit retina
39. Photoreceptor-bipolar cell transmission in the perfused retina eyecup of the mudpuppy
40. Serine transhydroxymethylase activity in vertebrate retina
41. Glutamate, GABA, and glycine in the human retina, an immunocytochemical investigation
42. Co-localization of glutamate and homocysteic acid immunoreactivities in human photoreceptor terminals
43. Colocalization of glutamate and glycine in bipolar cell terminals of the human retina
44. Coincidence of L-glutamate/L-aspartate transporter GLAST and glutamine synthetase GS. Immunoreactions in retinal glia, evidence for coupling of GLAST and GS in transmitter clearance
45. +-dependent L-glutamate transport activity in C6 glioma cells by phorbol ester
46. Müller cells in vascular and avascular retinae, a survey of seven mammals
47. Glial uptake of taurine in the rabbit retina
48. Glial uptake of GABA, glutamic acid, glutamine and glutathione in the rabbit retina
49. Characterization of the glutamate transporter in retinal cones of the tiger salamander
50. Localization and function of five glutamate transporters cloned from the salamander retina
51. Glutamine uptake at the blood-brain barrier is mediated by N-system transport
52. An excitatory amino-acid transporter with properties of a ligand-gated chloride channel
53. Pituitary adenylate cyclase-activating polypeptide PACAP., a neuron-derived peptide regulating glial glutamate transport and metabolism
54. Localisation of amino acid neurotransmitters during postnatal development of the rat retina
55. Molecular cloning and expression of a high affinity L-proline transporter expressed in putative glutamatergic pathways of rat brain
56. Characterization of glycine transport in cultured Müller glial cells from the retina
57. Neuronal soluble factors differentially regulate the expression of the GLT1 and GLAST glutamate transporters in cultured astroglia
58. The high-affinity glutamate transporters GLT1, GLAST, and EAAT4 are regulated via different signalling mechanisms
59. The reactivity of the gamma-aminobutyric acid transporter GAT-1 toward sulfhydryl reagents is conformationally sensitive. Identification of a major target residue
60. Sodium-dependent glutamate transport in Müller glial cells, regulation by phorbol esters
61. Neuronal and glial plasma membrane carrier-mediated uptake of L-homocysteate is not selectively blocked by beta-p-chlorophenylglutamate
62. Cloning and expression of a rat brain GABA transporter
63. Cloning, expression, and localization of a rat brain high-affinity glycine transporter
64. GABA receptor rho1 subunit interacts with a novel splice variant of the glycine transporter, GLYT-1
65. Functions of the two glutamate transporters GLAST and GLT-1 in the retina
66. Colocalization of [3H]muscimol and antisera to GABA and glutamic acid decarboxylase within the same neurons in monkey retina
67. Localization of glycine-containing neurons in the Macaca monkey retina
68. Immunocytochemical localization of three subtypes of GABA transporter in rat retina
69. Localization of GABA- and GAD-like immunoreactivity in the turtle retina
70. Production of specific antibodies against GABA transporter subtypes GAT1, GAT2, GAT3 and their application to immunocytochemistry
71. Accumulation of gamma-aminobutyric acid in diabetic rat retinal Müller cells evidenced by electron microscopic immunocytochemistry
72. Localization of glycine uptake and receptors in the cat retina
73. Glutathione and signal transduction in the mammalian CNS
74. Multiple gamma-Aminobutyric acid plasma membrane transporters GAT-1, GAT-2, GAT-3. In the rat retina
75. Glutamate immunoreactivity in the cat retina, a quantitative study
76. --dependent neurotransmitter transporters in bovine retina, identification and localization by in situ hybridization histochemistry
77. Amino acid neurochemistry of the vertebrate retina
78. Primary structure and functional characterization of a high-affinity glutamate transporter
79. Cystine/glutamate antiporter expression in retinal Müller glial cells, implications for DL-alpha-aminoadipate toxicity
80. Cloning of the human glycine transporter type 1, molecular and pharmacological characterization of novel isoform variants and chromosomal localization of the gene in the human and mouse genomes
81. Postnatal development of glycinergic neurons in the rabbit retina
82. Utilization of cysteine and cysteine precursors for the synthesis of glutathione in astroglial cultures, preference for cystine
83. Immunocytochemical localization of taurine in the mammalian retina
84. Taurine and its trophic effects in the retina
85. Taurine effect on neuritic growth from goldfish retinal explants
86. Ultrastructural demonstration of L-glutamate decarboxylase and cysteinesulfinic acid decarboxylace in rat retina by immunocytochemistry
87. Molecular cloning and expression of the rat EAAT4 glutamate transporter subtype
88. A comparison of the inhibitory actions of glycine and GABA on acetylcholine release from the rabbit retina
89. Cloning and expression of a cDNA encoding the transporter of taurine and beta-alanine in mouse brain
90. Cloning and expression of a glycine transporter from mouse brain
91. Molecular characterization of four pharmacologically distinct gamma-aminobutyric and transporters in mouse brain
92. Cloning and expression of a spinal cord- and brain-specific glycine transporter with novel structural features
93. Expression of a mouse brain cDNA encoding novel gamma-aminobutyric acid transporter
94. Transport-mediated release of endogenous glutamate in the vertebrate retina
95. Glycinergic synaptic inputs to bipolar cells in the salamander retina
96. Uptake of aspartic and glutamic acid by photoreceptors in goldfish retina
97. 3H glycine-accumulating neurons of the human retina
98. Patterns of glutamate immunoreactivity in the goldfish retina
99. Amino acid signatures in the normal cat retina
100. Cell types using glutamate as a neurotransmitter in the vertebrate retina
101. Transmitter circuits in the vertebrate retina
102. Selective retrograde labeling with D-[3H]-aspartate in afferents to the mammalian superior colliculus
103. Glycinergic amacrine cells of the rat retina
104. Taurine uptake activity in the rat retina, protein kinase C-independent inhibition by chelerythrine
105. Labeling and distribution of AII amacrine cells in the rabbit retina
106. Neuronal and glial localization of the GABA transporter GAT-1 in the carebellar cortex
107. Molecular cloning and functional expression of the human glycine transporter GlyT2 and chromosomal localisation of the gene in the human genome
108. Colocalization of GAD-like immunoreactivity and 3H-GABA uptake in amacrine cells of rabbit retina
109. GABA-ergic and glycinergic pathways in the inner plexiform layer of the goldfish retina
110. Concurrent downregulation of a glutamate transporter and receptor in glaucoma
111. Amino acid transmitter substances in the vertebrate retina
112. L-homocysteic acid - A possible bipolar cell transmitter in the rabbit retina
113. L-homocysteic acid, an endogenous excitotoxic ligand of the NMDA receptor
114. What constitutes a serotonergic neuron in the retina?
115. Involvement of the cystine transport system xc-in the macrophage-induced glutamate-dependent cytotoxicity to neurons
116. The axonal gamma-aminobutyric acid transporter GAT-1 is sorted to the apical membranes of polarized epithelial cells
117. Cloning and expression of a rat brain L-glutamate transporter
118. Transient expression of the glial glutamate transporters GLAST and GLT in hippocampal neurons in primary culture
119. Characterization of the 5′ region of the rat brain glycine transporter GLYT2 gene, identification of a novel isoform
120. Distribution of [35S]taurine in mouse retina after intravitreal and intravascular injection
121. Uptake of [3H]glycine and [3H]GABA by amacrine cells in the cat retina
122. [3H]taurine-accumulating neurons in the cat retina
123. Neurotransmitters in the retina
124. A combined Golgi and autoradiographic study of 3H-glycine-accumulating cone bipolar cells in the cat retina
125. Autoradiographic and immunocytochemical studies of glycine-containing neurons in the retina
126. Connectivity of glycine immunoreactive amacrine cells in the cat retina
127. Taurine, amino acid transmitters, and related molecules in the retina of the Australian lungfish Neoceratodus forsteri, a light-microscopic immunocytochemical and electron-microscopic study
128. Transport is the primary determinant of glycine content in retinal neurons
129. Changing patterns of spatial buffering of glutamate in developing rat retinae are mediated by the Müller and glutamate transporter GLAST
130. Developmental expression of excitatory amino acid transporter 5, a photoreceptor and bipolar cell glutamate transporter in rat retina
131. Aminoadipic acid transport, probing the role of the cystine-glutamate antiporter in the retina
132. Immunocytochemical analysis of the transport of arginine analogues into nitrergic neurons and other cells in the retina and pituitary
133. Tryptophan is present in glial cells and photoreceptors in the chicken retina
134. Distribution of the glycine transporter glyt-1 in mammalian and non-mammalian retinae
135. Distribution of glycine and the glycine transporter glyt-1 in the developing retina
136. Glutamate in some retinal neurons is derived solely from glia
137. GABA transamination regulates neuronal glutamate content in the retina
138. Blockade of glycine transport depletes retinal neurons of glycine and reveals a glycine accumulating system in rabbit cholinergic amacrine cells
139. Activity-dependent transport of GABA analogues into specific cell types demonstrated at high resolution using a novel immunocytochemical strategy
140. Localisation of a taurine transporter in the retina and other taurine-rich regions of the brain
141. Are neuronal glutamate transporters relevant in retinal glutamate homeostasis?
142. The glycine transporter GLYT2 is a reliable marker for glycine-immunoreactive neurons
143. Reabsorption of betaine in Henle's loops of rat kidney in vivo
144. Isolation and characterization of a skate retinal GABA transporter cDNA
145. Second messengers, trafficking-related proteins, and amino acid residues that contribute to the functional regulation of the rat brain GABA transporter GAT1
146. Localization of the glutamate transporter GLT-1 in rat and macaque monkey retinae
147. Fine tuning of glutamate uptake and degradation in glial cells, common transcriptional regulation of GLAST1 and GS
148. Differential expression of three glutamate transporter subtypes in the rat retina
149. High-affinity glutamate transporters in the rat retina, a major role of the glial glutamate transporter GLAST-1 in transmitter clearance
150. Neurotransmitter systems in the outer plexiform layer of mammalian retina
151. The mammalian brain high-affinity L-proline transporter is enriched preferentially in synaptic vesicles in a subpopulation of excitatory nerve terminals in rat forebrain
152. A study of possible excitatory effects of N-acetylaspartylglutamate in different in vivo and in vitro brain preparations
153. The family of sodium-dependent glutamate transporters, a focus on the GLT-1/EAAT2 subtype
154. Localization of neuronal and glial glutamate transporters
155. Pharmacological identification of retinal cells releasing taurine by light stimulation
156. Immunocytochemical localization of glutamate in normal and detached cat retina
157. Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins
158. Immunocytochemical localization of the high-affinity glutamate transporter, EAAC1, in the retina of representative vertebrate species
159. Competitive inhibition of N-acetylated-alpha-linked acidic dipeptidase activity by N-acetyl-L-aspartyl-beta-linked L-glutamate
160. Cloning and expression of a glycine transporter reveal colocalization with NMDA receptors
161. Cloning and expression of a high affinity taurine transporter from rat brain
162. Modulation by zinc of the glutamate transporters in glial cells and cones isolated from the tiger salamander retina
163. The actions of gamma-aminobutyric acid, glycine and their antagonists upon horizontal cells of the Xenopus retina
164. Control of NMDA receptor activation by a glycine transporter co-expressed in Xenopus oocytes
165. Glutamate receptors and circuits in the vertebrate retina
166. Analysis of excitatory and inhibitory spontaneous synaptic activity in mouse retinal ganglion cells
167. N-acetylaspartylglutamate immunoreactivity in neurons of the monkey's visual pathway
168. Anticonvulsant effects of some inhibitory neurotransmitter amino acids
169. Characterization of L-alpha-aminoadipic acid transport in cultured rat astrocytes
170. The dendritic architecture of the Cholinergic plexus in the rabbit retina, selective labeling by glycine accumulation in the presence of sarcosine
171. Neurotransmitter coupling through gap junctions in the retina
172. Molecular basis for differential inhibition of glutamate transporter subtypes by zinc ions
173. Cloning and functional identification of a neuronal glutamine transporter
174. The uptake of [3H]gamma-amino butyric acid and [3H]glycine by the isolated retina of the frog
175. Blockade of NAALADase, a novel neuroprotective strategy based on limiting glutamate and elevating NAAG
176. Electrophysiological characteristics of proton-coupled peptide transporter PEPT2 cloned from rat brain
177. Modulation of extracellular glutamate concentration in rat brain slices by cystine-glutamate exchange
178. Analysis of a glycinergic inhibitory pathway in the cat retina
179. Autoradiographic demonstration of ocular-dominance columns in the monkey striate cortex by means of transneuronal transport
180. Uptake, metabolism, and release of N-[3H]acetylaspartylgultamate by the avian retina
181. Transport of cysteate by synaptosomes isolated from rat brain, evidence that it utilizes the same transporter as aspartate, glutamate, and cysteine sulfinate
182. The DAPI amacrine cells of the rabbit retina
183. EAAT4 is a post-synaptic glutamate transporter at Purkinje cell synapses
184. Glutamate-, GABA-, and GAD-immunoreactivities co-localize in bipolar cells of tiger salamander retina
185. Localization of aspartate-like immunoreactivity in the retina of the turtle Pseudemys scripta
186. GABAergic mechanisms in the retina
187. Glycine transporters are differentially expressed among CNS cells
188. Glycine transporters are differentially expressed among CNS cells
189. Neuronal dependency of the glycine transporter GLYT1 expression in glial cells
190. Age-related macular degeneration, review of pathogenesis
191. L-homocysteic acid selectively activates N-methyl-D-aspartate receptors of rat retinal ganglion cells