Expression of multidrug resistance-associated protein (MRP) in human retinal pigment epithelial cells and its interaction with BAPSG, a novel aldose reductase inhibitor

Pharmaceutical Research

Volumn 18, Issue 5, 2001, Pages 565-572

  Aukunuru, J V ^a   Sunkara, G ^a   Bandi, N ^a   Thoreson, W B ^b   Kompella, U B ^a,b  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Aldose reductase inhibitor; Fluorescein; MRP; RPE cells

Indexed keywords

ALDOSE REDUCTASE INHIBITOR; FLUORESCEIN; MULTIDRUG RESISTANCE PROTEIN; N [4 (BENZOYLAMINO)PHENYLSULFONYL]GLYCINE; UNCLASSIFIED DRUG; VISUAL PIGMENT;

ARTICLE; CELL LINE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG PROTEIN BINDING; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN INTERACTION;

ALDEHYDE REDUCTASE; ANTIMETABOLITES; BLOTTING, WESTERN; CELL LINE; COLD; ENZYME INHIBITORS; EPITHELIAL CELLS; FLUORESCEIN; GLYCINE; HUMANS; INDICATORS AND REAGENTS; P-GLYCOPROTEIN; PIGMENT EPITHELIUM OF EYE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SULFONES; TETRAZOLIUM SALTS; THIAZOLES;

EID: 0034950241     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011060705599     Document Type: Article

References (28)

1. Transport mechanisms in the retinal pigment epithelium
2. Movement of fluorescein and its glucuronide across retinal pigment epithelium-choroid
3. Membrane topology and glycosylation of the human multidrug resistance-associated protein
4. Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of multidrug resistance-associated protein gene (MRP1) in human cancer cell lines
5. Expression of human MRP 6, a homologue of multidrug resistance protein gene MRP1 in tissues and cancer cells
6. Transport properties of the multidrug resistance-associated protein (MRP) in human tumor cells
7. Expression of various multidrug resistance protein (MRP) homologues in brain microvessel endothelial cells
8. Choroid plexus epithelial expression of MDR1 P-glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid-permeability barrier
9. Expression of multidrug resistance-associated protein (MRP) in brain microvessel endothelial cells
10. ARPE- 19, a human retinal pigment epithelial cell line with differentiated properties
11. Use of the ARPE-19 cell line as a model of RPE polarity: Basolateral secretion of FGF 5
12. Polarized secretion of IL-6 and IL-8 by human retinal pigment epithelial cells
13. An aldose reductase inhibitor and aminoguanidine prevent vascular endothelial growth factor expression in rats with long-term galactosemia
14. Insulin-induced vascular endothelial growth factor expression in retina
15. In vitro inhibitory activity of substituted N-benzenesulfonylglycine derivatives
16. Influence of oxygen free radicals, 4-hydroxynonenal, 15-HETE, and aldose reductase pathway on vascular endothelial growth factor secretion from human retinal pigment epithelial cells
17. Inhibition of multidrug resistance-associated protein (MRP) functional activity with pluronic block copolymers
18. Lysophosphatidic acid stimulates proliferation of human retinal pigment epithelial cells
19. In-vitro hydrolysis, permeability, and ocular uptake of Prodrugs of N-[4-(benzoylamino) phenylsulfonyl]glycine, a novel aldose reductase inhibitor
20. The expression of multidrug resistance-associated protein (MRP) in pancreatic adenocarcinoma cell lines
21. Indomethacin-mediated reversal of multidrug resistance and drug efflux in human and murine cell lines over expressing MRP, but not P-glycoprotein
22. Probenecid reverses multidrug resistance in multidrug resistance associated-protein-overexpressing HL60/AR, H69/AR cells but not in P-glycoprotein-over expressing HL60/Tax and P388/ADR cells
23. Expression of the multidrug resistance-associated protein (MRP) and chemoresistance of human non-small-cell lung cancer cells
24. Chemosensitization and drug accumulation effects of cyclosporin A, PSC-833 and verapamil in human MDR large cell lung cancer cells expressing a 190 kD membrane protein distinct from P-glycoprotein
25. Detection of MRP1mRNA in human tumors and tumor cell lines by in situ RT-PCR
26. Organic anion transport in the central nervous system: A study of fluorescein CNS distribution kinetics
27. Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5, and MDR3 P-glycoprotein with a panel of monoclonal antibodies
28. Rabbit corneal and conjunctival permeability of the novel aldose reductase inhibitors: N-[4-(benzoylamino)phenyl] sulphonyl glycines and N-benzyoyl-N-phenyl glycines